KR870010040A - Method for preparing N- (2-pyrimidinyl) piperazinyl butyl azaspiro decanedione - Google Patents

Method for preparing N- (2-pyrimidinyl) piperazinyl butyl azaspiro decanedione Download PDF

Info

Publication number
KR870010040A
KR870010040A KR1019860002799A KR860002799A KR870010040A KR 870010040 A KR870010040 A KR 870010040A KR 1019860002799 A KR1019860002799 A KR 1019860002799A KR 860002799 A KR860002799 A KR 860002799A KR 870010040 A KR870010040 A KR 870010040A
Authority
KR
South Korea
Prior art keywords
azaspiro
preparing
decanedione
pyrimidinyl
formula
Prior art date
Application number
KR1019860002799A
Other languages
Korean (ko)
Other versions
KR890000727B1 (en
Inventor
김기원
이병석
김정수
Original Assignee
이금기
일 동 제 약 주식회사
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 이금기, 일 동 제 약 주식회사 filed Critical 이금기
Priority to KR8602799A priority Critical patent/KR890000727B1/en
Publication of KR870010040A publication Critical patent/KR870010040A/en
Application granted granted Critical
Publication of KR890000727B1 publication Critical patent/KR890000727B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

내용 없음No content

Description

N-(2-피리미닐) 피페라지닐 부틸 아자스피로 데칸디온의 제조방법Process for preparing N- (2-pyriminyl) piperazinyl butyl azaspiro decanedione

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (2)

구조식(ⅩⅡ)로 표시되는 8-(4-아미노부틸)-8-아자스피로 [4,5]-데칸-,7,9-디온과 구조식(ⅩⅢ)로 표시되는 2-(N,N-디할로에틸아미노)피리미딘을 반응시켜서 구조식(Ⅰ)의 8-[4-[4-(2-피리미피디닐)-1-페라지닐]-부틸]-8-아자스피로 [4,5]-데칸-7,9-디온을 제조하는 방법.8- (4-aminobutyl) -8-azaspiro [4,5] -decane-, 7,9-dione represented by formula (XII) and 2- (N, N-dihal represented by formula (XIII) Reacting with ethylethyl) pyrimidine to yield 8- [4- [4- (2-pyrimidydinyl) -1-ferazinyl] -butyl] -8-azaspiro [4,5]-of formula (I). Method for preparing decan-7,9-dione. 윗식에서, X1, 및 X2는 각각 염소, 브롬, 요오드 등의 할로겐 원자를 나타낸다.In the above formula, X 1 and X 2 each represent a halogen atom such as chlorine, bromine, iodine or the like. 제1항에서 반응을 염기존재하에 행하는 방법.The method of claim 1 wherein the reaction is carried out in the presence of a base. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR8602799A 1986-04-12 1986-04-12 Process for preparing n-(2-pyrimidinyl) piperazinyl buthylazaspirodecanedion KR890000727B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR8602799A KR890000727B1 (en) 1986-04-12 1986-04-12 Process for preparing n-(2-pyrimidinyl) piperazinyl buthylazaspirodecanedion

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR8602799A KR890000727B1 (en) 1986-04-12 1986-04-12 Process for preparing n-(2-pyrimidinyl) piperazinyl buthylazaspirodecanedion

Publications (2)

Publication Number Publication Date
KR870010040A true KR870010040A (en) 1987-11-30
KR890000727B1 KR890000727B1 (en) 1989-03-30

Family

ID=19249377

Family Applications (1)

Application Number Title Priority Date Filing Date
KR8602799A KR890000727B1 (en) 1986-04-12 1986-04-12 Process for preparing n-(2-pyrimidinyl) piperazinyl buthylazaspirodecanedion

Country Status (1)

Country Link
KR (1) KR890000727B1 (en)

Also Published As

Publication number Publication date
KR890000727B1 (en) 1989-03-30

Similar Documents

Publication Publication Date Title
RU1838308C (en) Method of synthesis of derivatives of substituted (1h-azole-1-ylmethyl)-benztriazole or their pharmaceutically acceptable salts of acid addition
ATE67497T1 (en) PROCESS FOR THE PREPARATION OF THIAZOLIDINEDIONE DERIVATIVES.
KR860003206A (en) Method for preparing benzoyl phenylurea
FR2647787B1 (en) NOVEL THIAZOLYLALKOXYACRYLATES, THEIR PREPARATION PROCESS, THEIR APPLICATION AS FUNGICIDES AND THEIR PREPARATION INTERMEDIATES
SE8600174L (en) NEW PROCEDURE FOR THE PREPARATION OF N- (2-PYRIMIDINYL) -PIPERAZINYLALKYLAZASPIROALCANDIONS
FI882919A0 (en) FOERFARANDE.
KR880005136A (en) Quinoline compound, preparation method thereof, and anticancer agent containing the compound as an active ingredient
ATE78269T1 (en) ELECTROCOAT.
ES2054037T3 (en) SYNTHESIS PROCEDURE OF AZIDO-3'-DESOXI-3'-THYMIDINE AND ANALOGS.
KR870010040A (en) Method for preparing N- (2-pyrimidinyl) piperazinyl butyl azaspiro decanedione
KR850000442A (en) Method for preparing 7-piperidino-1,2,3,5-tetrahydro imidazo [2,1-b] quinazolin-2-one
KR850000412A (en) Method for preparing pyrimidine derivative
PT74293B (en) CHEMICAL METHODS AND INTERMEDIATES FOR PREPARING SUBSTITUTED PYRIMIDINONES
KR930700435A (en) Salts of dithiocarbamic acid, a method for producing the same, and a method for producing isothiocyanates using the salts of the dithiocarbamic acid
KR870010041A (en) Method for preparing N- (2-pyrimidinyl) piperazinyl butyl azaspiro decandionone
SE8602523D0 (en) 2-ALKYL OR -ARALKYLTIO-1-CYCLOALKEN-1-CARBOXAMIDES AND THEIR SULPHOXIDES, SET FOR THEIR PREPARATION AND THEIR USE FOR THE SYNTHESIS OF TRI- AND 4,5-TETRAMETHYLENE-4-ISOTIAZE
KR870008857A (en) Indenopyrimidine Derivatives
IT1212140B (en) PROCESS FOR THE PREPARATION OF 2,4-DIAMINE-6- (1-PIPERIDINYL) -PIRI MI-DIN-N-OXIDE.
KR880013921A (en) Method for preparing 4,4-dimethyl-l- [4- [4- (2-pyrimidinyl) -l-piperazinyl] butyl] -2,6-piperidine dione
KR880001628A (en) Synthesis of Bicyclic Aromatic Sulfonyl Chloride
KR880013922A (en) Method for preparing 4,4-dimethyl-l- [4- [4- (2-pyrimidinyl) -l-piperazinyl] butyl] -2,6-piperidine dione
KR870007136A (en) Method for preparing 2,4-diamino-6-halo alkylpyrimidine
KR870007908A (en) Manufacturing method of indene compound
KR870005989A (en) Novel isoindolin derivatives and preparation method thereof
KR890006605A (en) Halogen Substituted Isothiazolone Process

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
G160 Decision to publish patent application
O035 Opposition [patent]: request for opposition
E701 Decision to grant or registration of patent right
O073 Decision to grant registration after opposition [patent]: decision to grant registration
GRNT Written decision to grant
FPAY Annual fee payment

Payment date: 19930330

Year of fee payment: 12

LAPS Lapse due to unpaid annual fee