KR860002527A - Method for preparing α-L-aspartyl-L-phenylalanine alkyl ester - Google Patents

Method for preparing α-L-aspartyl-L-phenylalanine alkyl ester Download PDF

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Publication number
KR860002527A
KR860002527A KR1019840005804A KR840005804A KR860002527A KR 860002527 A KR860002527 A KR 860002527A KR 1019840005804 A KR1019840005804 A KR 1019840005804A KR 840005804 A KR840005804 A KR 840005804A KR 860002527 A KR860002527 A KR 860002527A
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KR
South Korea
Prior art keywords
formula
aspartyl
preparing
alkyl ester
phenylalanine alkyl
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Application number
KR1019840005804A
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Korean (ko)
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KR880002303B1 (en
Inventor
1) 박현필(외
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임철수
서울미원 주식회사
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Priority to KR1019840005804A priority Critical patent/KR880002303B1/en
Publication of KR860002527A publication Critical patent/KR860002527A/en
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Publication of KR880002303B1 publication Critical patent/KR880002303B1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)

Abstract

내용 없음No content

Description

α-L-아스파틸-L-페닐알라닌 알킬 에스테르 제조방법Method for preparing α-L-aspartyl-L-phenylalanine alkyl ester

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

Claims (2)

구조식(Ⅱ)의 아스파라긴산과 구조식(Ⅲ)의 플로오레닐-메톡시 클로라이드를 공지의 에칠에테르, 에칠프로피온네이트, 테트라하이드로후란, 디옥산, 에칠에테르 클로로포름, N-N-디메틸포름아미드, 벤젠, 톨루엔, 빙초산등의 의유기용매중에서 구조식(Ⅴ)의 디싸이클로헥실 카보이미드와 반응시켜 구조식(Ⅳ)의 산무수물을 제조한후 구조식(Ⅳ)의-페닐알라닌 메칠에스 테르와 반응시켜 구조식(Ⅰ)의 α-L-아스파틸-L-페닐알라닌 메틸에스테르를 제조하는 방법.Aspartic acid of formula (II) and fluorenyl-methoxy chloride of formula (III) are known as ethyl ether, ethyl propionate, tetrahydrofuran, dioxane, ethyl ether chloroform, NN-dimethylformamide, benzene, toluene , An acid anhydride of formula (IV) was prepared by reacting with dicyclohexyl carbodiimide of formula (V) in an organic solvent such as glacial acetic acid, and then reacted with -phenylalanine methyl ester of formula (IV). Process for preparing α-L-aspartyl-L-phenylalanine methyl ester. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019840005804A 1984-09-21 1984-09-21 Process for the preparation of d-l-aspartyl-l-phenylalkylester KR880002303B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019840005804A KR880002303B1 (en) 1984-09-21 1984-09-21 Process for the preparation of d-l-aspartyl-l-phenylalkylester

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019840005804A KR880002303B1 (en) 1984-09-21 1984-09-21 Process for the preparation of d-l-aspartyl-l-phenylalkylester

Publications (2)

Publication Number Publication Date
KR860002527A true KR860002527A (en) 1986-04-26
KR880002303B1 KR880002303B1 (en) 1988-10-22

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ID=19235488

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840005804A KR880002303B1 (en) 1984-09-21 1984-09-21 Process for the preparation of d-l-aspartyl-l-phenylalkylester

Country Status (1)

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KR (1) KR880002303B1 (en)

Also Published As

Publication number Publication date
KR880002303B1 (en) 1988-10-22

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Free format text: OPPOSITION NUMBER: 001988001066; OPPOSITION DATE: 19881221