KR840009308A - Method for preparing pyrazino isoquinoline derivatives substituted with rings - Google Patents

Method for preparing pyrazino isoquinoline derivatives substituted with rings Download PDF

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Publication number
KR840009308A
KR840009308A KR1019830001897A KR830001897A KR840009308A KR 840009308 A KR840009308 A KR 840009308A KR 1019830001897 A KR1019830001897 A KR 1019830001897A KR 830001897 A KR830001897 A KR 830001897A KR 840009308 A KR840009308 A KR 840009308A
Authority
KR
South Korea
Prior art keywords
rings
preparing
derivatives substituted
isoquinoline derivatives
pyrazino
Prior art date
Application number
KR1019830001897A
Other languages
Korean (ko)
Inventor
이한구, (외 2)
Original Assignee
이성훈
주식회사 중외제약
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 이성훈, 주식회사 중외제약 filed Critical 이성훈
Priority to KR1019830001897A priority Critical patent/KR840009308A/en
Publication of KR840009308A publication Critical patent/KR840009308A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

내용 없음No content

Description

환으로 치환된 피라지노 이소퀴놀린 유도체의 제조방법Method for preparing pyrazino isoquinoline derivatives substituted with rings

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (5)

구조식(4) 화합물에 구조식(3) 화합물을 반응시켜 구조식(2) 화합물을 제조한 후 포스포러스옥시클로라이드로 환화반응을 시킨다음, 소디움보로하이드라이드로 환원시켜 구조식(1) 화합물을 제조하는 방법.A compound of formula (3) is reacted with a compound of formula (4) to prepare a compound of formula (2), and then cyclized with phosphorus oxychloride, followed by reduction with sodium borohydride to produce compound (1). Way. 상기식중 M은 K,Na,Li등이다.Wherein M is K, Na, Li, or the like. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019830001897A 1983-05-04 1983-05-04 Method for preparing pyrazino isoquinoline derivatives substituted with rings KR840009308A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019830001897A KR840009308A (en) 1983-05-04 1983-05-04 Method for preparing pyrazino isoquinoline derivatives substituted with rings

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019830001897A KR840009308A (en) 1983-05-04 1983-05-04 Method for preparing pyrazino isoquinoline derivatives substituted with rings

Publications (1)

Publication Number Publication Date
KR840009308A true KR840009308A (en) 1984-12-26

Family

ID=55176749

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019830001897A KR840009308A (en) 1983-05-04 1983-05-04 Method for preparing pyrazino isoquinoline derivatives substituted with rings

Country Status (1)

Country Link
KR (1) KR840009308A (en)

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Legal Events

Date Code Title Description
E902 Notification of reason for refusal
E601 Decision to refuse application