KR840009306A - Method for preparing pyrazino isoquinoline derivatives substituted with rings - Google Patents

Method for preparing pyrazino isoquinoline derivatives substituted with rings Download PDF

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Publication number
KR840009306A
KR840009306A KR1019830001895A KR830001895A KR840009306A KR 840009306 A KR840009306 A KR 840009306A KR 1019830001895 A KR1019830001895 A KR 1019830001895A KR 830001895 A KR830001895 A KR 830001895A KR 840009306 A KR840009306 A KR 840009306A
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KR
South Korea
Prior art keywords
rings
preparing
derivatives substituted
isoquinoline derivatives
pyrazino
Prior art date
Application number
KR1019830001895A
Other languages
Korean (ko)
Inventor
이한구, (외 2)
Original Assignee
이성훈
주식회사 중외제약
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 이성훈, 주식회사 중외제약 filed Critical 이성훈
Priority to KR1019830001895A priority Critical patent/KR840009306A/en
Publication of KR840009306A publication Critical patent/KR840009306A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

내용 없음No content

Description

환으로 치환된 피라지노 이소퀴놀린 유도체의 제조방법Method for preparing pyrazino isoquinoline derivatives substituted with rings

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (4)

구조식(4) 화합물인 1-클로로메틸-1,2,3,4-테트라하이드로이 소퀴놀린과 클로로아세틸클로라이드를 축합반응을 하여 구조식(3) 화합물을 제조한후, 이를 구조식(2)로 표시되는 싸이클로헥실카르보닐 아민금속염과 축합반응시켜 구조식(1) 화합물을 제조하는 방법.Condensation reaction of 1-chloromethyl-1,2,3,4-tetrahydroisoquinoline and chloroacetyl chloride as a compound of formula (4) to prepare a compound of formula (3), which is represented by formula (2) A condensation reaction with cyclohexylcarbonyl amine metal salt to prepare the compound of formula (1). 상기식중 M은 K,Na,Li등이다.Wherein M is K, Na, Li, or the like. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019830001895A 1983-05-04 1983-05-04 Method for preparing pyrazino isoquinoline derivatives substituted with rings KR840009306A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019830001895A KR840009306A (en) 1983-05-04 1983-05-04 Method for preparing pyrazino isoquinoline derivatives substituted with rings

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019830001895A KR840009306A (en) 1983-05-04 1983-05-04 Method for preparing pyrazino isoquinoline derivatives substituted with rings

Publications (1)

Publication Number Publication Date
KR840009306A true KR840009306A (en) 1984-12-26

Family

ID=55176747

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019830001895A KR840009306A (en) 1983-05-04 1983-05-04 Method for preparing pyrazino isoquinoline derivatives substituted with rings

Country Status (1)

Country Link
KR (1) KR840009306A (en)

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Legal Events

Date Code Title Description
E902 Notification of reason for refusal
E601 Decision to refuse application