KR840004366A - 과불소탄화수소류 투약용 부형제 - Google Patents
과불소탄화수소류 투약용 부형제 Download PDFInfo
- Publication number
- KR840004366A KR840004366A KR1019830001426A KR830001426A KR840004366A KR 840004366 A KR840004366 A KR 840004366A KR 1019830001426 A KR1019830001426 A KR 1019830001426A KR 830001426 A KR830001426 A KR 830001426A KR 840004366 A KR840004366 A KR 840004366A
- Authority
- KR
- South Korea
- Prior art keywords
- perfluorohydrocarbon
- excipient
- composition
- excipient consists
- therapeutic agent
- Prior art date
Links
- 239000000546 pharmaceutical excipient Substances 0.000 title claims 24
- 239000000203 mixture Substances 0.000 claims 12
- 239000004215 Carbon black (E152) Substances 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 229930195733 hydrocarbon Natural products 0.000 claims 3
- 150000002430 hydrocarbons Chemical class 0.000 claims 3
- 229940124597 therapeutic agent Drugs 0.000 claims 3
- LWRNQOBXRHWPGE-UHFFFAOYSA-N 1,1,2,2,3,3,4,4,4a,5,5,6,6,7,7,8,8a-heptadecafluoro-8-(trifluoromethyl)naphthalene Chemical compound FC1(F)C(F)(F)C(F)(F)C(F)(F)C2(F)C(C(F)(F)F)(F)C(F)(F)C(F)(F)C(F)(F)C21F LWRNQOBXRHWPGE-UHFFFAOYSA-N 0.000 claims 2
- GFVSQLYBVUOTHL-UHFFFAOYSA-N 2,3,4,5,6-pentafluoro-2-[1,1,2,2,3,4,4,4-octafluoro-3-(trifluoromethyl)butyl]pyran Chemical group FC1=C(F)C(F)=C(F)C(F)(C(F)(F)C(F)(F)C(F)(C(F)(F)F)C(F)(F)F)O1 GFVSQLYBVUOTHL-UHFFFAOYSA-N 0.000 claims 2
- CJFUEPJVIFJOOU-UHFFFAOYSA-N 2-perfluorobutyltetrahydrofuran Chemical compound FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C1CCCO1 CJFUEPJVIFJOOU-UHFFFAOYSA-N 0.000 claims 2
- 229950011087 perflunafene Drugs 0.000 claims 2
- UWEYRJFJVCLAGH-IJWZVTFUSA-N perfluorodecalin Chemical compound FC1(F)C(F)(F)C(F)(F)C(F)(F)[C@@]2(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)[C@@]21F UWEYRJFJVCLAGH-IJWZVTFUSA-N 0.000 claims 2
- LIXDPHHZLNLBGW-UHFFFAOYSA-N 1,2,2,3,3,4,4,5,5,6,6-undecafluoro-N,N-bis(trifluoromethyl)cyclohexan-1-amine Chemical compound FC(F)(F)N(C(F)(F)F)C1(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C1(F)F LIXDPHHZLNLBGW-UHFFFAOYSA-N 0.000 claims 1
- REBUAPRBRNJQKD-UHFFFAOYSA-N FC(C(C(F)(F)F)(F)F)(C(N(C(F)(F)F)F)(F)F)F Chemical compound FC(C(C(F)(F)F)(F)F)(C(N(C(F)(F)F)F)(F)F)F REBUAPRBRNJQKD-UHFFFAOYSA-N 0.000 claims 1
- 150000001335 aliphatic alkanes Chemical class 0.000 claims 1
- JWDVRIOQNXFNES-UHFFFAOYSA-N n,1,1,1-tetrafluoro-n-(trifluoromethyl)methanamine Chemical compound FC(F)(F)N(F)C(F)(F)F JWDVRIOQNXFNES-UHFFFAOYSA-N 0.000 claims 1
- RVZRBWKZFJCCIB-UHFFFAOYSA-N perfluorotributylamine Chemical compound FC(F)(F)C(F)(F)C(F)(F)C(F)(F)N(C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F RVZRBWKZFJCCIB-UHFFFAOYSA-N 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/02—Halogenated hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (23)
- 37℃에서 약 1-16mmHg의 증가압을 가진 과불소탄화수소 부형제와 치료약제로 구성된 제약용 조성물
- 37℃에서 약 1-16mmHg의 증기압을 가진 과불소탄화수소 부형제와 치료약제로 구성된 국소치료제용 조성물
- 제1항 또는 제2항에 있어서 상기 과불소탄화수소 부형제가 과불소 알칸으로 구성된 조성물
- 제1항 또는 제2항에 있어서 상기 과불소탄화수소 부형제가 과불소사이클로알칸으로 구성된 조성물
- 제1항 또는 제2항에 있어서 상기 과불소탄화수소 부형제가 C9-15의 과불소트리알킬아민으로 구성된 조성물
- 제1항 또는 제2항에 있어서 과불소탄화수소 부형제가 과불소데칼린으로 구성된 조성물
- 제1항 또는 제2항에 있어서 과불소탄화수소 부형제가 과불소트리불틸아민으로 구성된 조성물
- 제1항 또는 제2항에 있어서 상기 과불소탄화수소 부형제가 과불소메틸데칼린으로 구성된 조성물
- 제1항 또는 제2항에 있어서 상기 과불소탄화수소 부형제가 과불소사이클로헥실티에틸아민으로 구성된 조성물
- 제1항 또는 제2항에 있어서 상기 과불소탄화수소 부형제가 과불소이소펜틸피란인 조성물
- 제1항 또는 제2항에 있어서 상기 과불소탄화수소 부형제가 과불소디메틸아민으로 구성된 조성물
- 제1항 또는 제2항에 있어서 과불소탄화수소 부형제가 과불소부틸테트라하이드로푸란으로 구성된 조성물
- 37℃에서 약 1-16mmHg의 증가압을 갖는 과불탄화수소 부형제와 치료약제 유효량으로 구성된 조성물을 투여하는 것으로 구성된 치료약제의 적용법
- 제13항에 있어서, 상기 과불소탄화수소 부형제가 과불소알칸으로 구성된 방법
- 제13항에 있어서, 상기 과불소탄화수소 부형제가 과불소사이클로알칸으로 구성된 방법
- 제13항에 있어서, 상기 과불소탄화수소 부형제가 C9-15의 과불소트리알킬아민으로 구성된 방법
- 제13항에 있어서, 상기 과불소탄화수소 부형제가 과불소데칼린으로 구성된 방법
- 제13항에 있어서, 상기 과불소탄화수소 부형제가 과불소트리부틸아민으로 구성된 방법
- 제13항에 있어서, 상기 과불소탄화수소 부형제가 과불소메틸데칼린으로 구성된 방법
- 제13항에 있어서, 상기 과불소탄화수소 부형제가 과불소사이클로헥실디메틸아민으로 구성된 방법
- 제13항에 있어서, 상기 과불소탄화수소 부형제가 과불소이소펜틸피란으로 구성된 방법
- 제13항에 있어서, 상기 과불소탄화수소 부형제가 과불소부틸메틸아민으로 구성된 방법
- 제13항에 있어서, 상기 과불소탄화수소 부형제가 과불소부틸테트라하이드로푸란으로 구성된 방법※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36553982A | 1982-04-05 | 1982-04-05 | |
US365,539 | 1982-04-05 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR840004366A true KR840004366A (ko) | 1984-10-15 |
KR880002038B1 KR880002038B1 (ko) | 1988-10-13 |
Family
ID=23439275
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019830001426A KR880002038B1 (ko) | 1982-04-05 | 1983-04-06 | 과불소-치환 화합물을 부형제로서 포함하는 약제 조성물 |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0091313B1 (ko) |
KR (1) | KR880002038B1 (ko) |
AT (1) | ATE56138T1 (ko) |
AU (1) | AU557980B2 (ko) |
CA (1) | CA1295948C (ko) |
DE (1) | DE3381854D1 (ko) |
GR (1) | GR78151B (ko) |
IE (1) | IE56412B1 (ko) |
IL (1) | IL68456A (ko) |
NZ (1) | NZ203802A (ko) |
PT (1) | PT76504B (ko) |
WO (1) | WO1983003544A1 (ko) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU559559B2 (en) * | 1982-08-17 | 1987-03-12 | Suntech, Inc. | Perfluorocarbon emulsions and their preparation and use in therapy |
US5124154A (en) * | 1990-06-12 | 1992-06-23 | Insite Vision Incorporated | Aminosteroids for ophthalmic use |
US6458376B1 (en) | 1990-09-27 | 2002-10-01 | Allergan, Inc. | Nonaqueous fluorinated drug delivery suspensions |
US5518731A (en) * | 1990-09-27 | 1996-05-21 | Allergan, Inc. | Nonaqueous fluorinated drug delivery vehicle suspensions |
US5173298A (en) * | 1990-09-27 | 1992-12-22 | Allergan, Inc. | Nonaqueous fluorinated drug delivery vehicle suspensions |
DE69226372T2 (de) * | 1991-11-14 | 1999-04-01 | Alliance Pharma | Vorrichtung zur teilweisen flüssigen beatmung mit fluorkohlenwasserstoffen |
DE4221268C2 (de) * | 1992-06-26 | 1997-06-12 | Lancaster Group Ag | Verwendung eines Dermatikums zur Unterstützung des Sauerstofftransportes in der Haut |
US5643601A (en) * | 1992-06-26 | 1997-07-01 | Lancaster Group Ag | Phospholipid-and fluorocarbon-containing cosmetic |
DE4221256C2 (de) * | 1992-06-26 | 1997-07-10 | Lancaster Group Ag | Galenische Zusammensetzung für die topische Anwendung |
US5340572A (en) * | 1993-02-08 | 1994-08-23 | Insite Vision Incorporated | Alkaline ophthalmic suspensions |
ATE196734T1 (de) * | 1993-08-18 | 2000-10-15 | Alcon Lab Inc | Zusammensetzungen von ergolinderivaten zur behandlung des glaukoms |
ATE206441T1 (de) | 1994-03-04 | 2001-10-15 | Univ Washington | Block- und pfropfcopolymere und dazu gehöriges verfahren |
US5480914A (en) * | 1994-05-06 | 1996-01-02 | Allergan, Inc. | Nonaqueous thixotropic drug delivery suspensions and methods of their use |
US5874469A (en) * | 1996-01-05 | 1999-02-23 | Alcon Laboratories, Inc. | Fluoroalkyl hydrocarbons for administering water insoluble or unstable drugs |
AU2001211986B2 (en) * | 2000-10-13 | 2007-04-26 | Cambridge Biostability Ltd. | Composition and method for stable injectable liquids |
DE60043459D1 (de) * | 2000-10-13 | 2010-01-14 | Cambridge Biostability Ltd | Pharmazeutische flüssige Suspensionen |
DE102006040450B3 (de) * | 2006-08-24 | 2008-04-24 | Coty Prestige Lancaster Group Gmbh | Verwendung einer Zusammensetzung für die Hautbehandlung nach Röntgenbestrahlung |
CN104755073B (zh) * | 2012-09-12 | 2017-12-26 | 诺瓦利克有限责任公司 | 半氟化烷烃组合物 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2968628A (en) * | 1958-10-17 | 1961-01-17 | Shulton Inc | Propellant composition |
US3282781A (en) * | 1960-11-25 | 1966-11-01 | Merck & Co Inc | Inhalant compositions |
BE629985A (ko) * | 1962-11-29 | |||
US3490923A (en) * | 1966-07-28 | 1970-01-20 | Du Pont | Aerosol propellant composition used in dispensing foods |
US3958014A (en) * | 1970-09-05 | 1976-05-18 | The Green Cross Corporation | Process for preparing injection-purpose fluorocarbon emulsion capable of carrying oxygen |
US3823091A (en) * | 1971-05-19 | 1974-07-09 | Green Cross Corp | Stable emulsion of fluorocarbon particles |
US3929662A (en) * | 1973-12-18 | 1975-12-30 | Wave Energy Systems | Liquid or gas phase sterilizing and cleaning composition containing an aldehyde and a fluoro or perfluoro compound |
US4187252A (en) * | 1977-08-26 | 1980-02-05 | Suntech, Inc. | Tetramethylpentane blood substitutes |
US4110474A (en) * | 1977-08-26 | 1978-08-29 | Suntech, Inc. | Tetramethylpentane blood substitutes |
US4252827A (en) * | 1979-05-23 | 1981-02-24 | The Green Cross Corporation | Oxygen-transferable fluorocarbon emulsion |
US4352789A (en) * | 1980-03-17 | 1982-10-05 | Minnesota Mining And Manufacturing Company | Aerosol compositions containing finely divided solid materials |
US4452818A (en) * | 1982-03-19 | 1984-06-05 | Haidt Sterling J | Extraocular method of treating the eye with liquid perfluorocarbons |
JPH08221312A (ja) * | 1995-02-14 | 1996-08-30 | Hitachi Ltd | メモリカード装置 |
-
1983
- 1983-04-04 GR GR70977A patent/GR78151B/el unknown
- 1983-04-05 WO PCT/US1983/000484 patent/WO1983003544A1/en unknown
- 1983-04-05 EP EP83301908A patent/EP0091313B1/en not_active Expired - Lifetime
- 1983-04-05 AT AT83301908T patent/ATE56138T1/de not_active IP Right Cessation
- 1983-04-05 AU AU13138/83A patent/AU557980B2/en not_active Ceased
- 1983-04-05 CA CA000425162A patent/CA1295948C/en not_active Expired - Lifetime
- 1983-04-05 DE DE8383301908T patent/DE3381854D1/de not_active Expired - Lifetime
- 1983-04-05 PT PT76504A patent/PT76504B/pt not_active IP Right Cessation
- 1983-04-06 KR KR1019830001426A patent/KR880002038B1/ko not_active IP Right Cessation
- 1983-04-06 IE IE776/83A patent/IE56412B1/en not_active IP Right Cessation
- 1983-04-06 NZ NZ203802A patent/NZ203802A/en unknown
- 1983-04-21 IL IL68456A patent/IL68456A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IL68456A0 (en) | 1983-07-31 |
EP0091313A2 (en) | 1983-10-12 |
EP0091313B1 (en) | 1990-09-05 |
IL68456A (en) | 1989-09-28 |
ATE56138T1 (de) | 1990-09-15 |
CA1295948C (en) | 1992-02-18 |
NZ203802A (en) | 1985-07-31 |
DE3381854D1 (de) | 1990-10-11 |
AU557980B2 (en) | 1987-01-15 |
PT76504A (en) | 1983-05-01 |
IE56412B1 (en) | 1991-07-31 |
EP0091313A3 (en) | 1985-05-22 |
GR78151B (ko) | 1984-09-26 |
WO1983003544A1 (en) | 1983-10-27 |
PT76504B (en) | 1986-02-27 |
KR880002038B1 (ko) | 1988-10-13 |
AU1313883A (en) | 1983-10-13 |
IE830776L (en) | 1983-10-05 |
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