KR830008989A - Process for preparing substituted carboxylic acid ammonium salts - Google Patents

Process for preparing substituted carboxylic acid ammonium salts Download PDF

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Publication number
KR830008989A
KR830008989A KR1019820000650A KR820000650A KR830008989A KR 830008989 A KR830008989 A KR 830008989A KR 1019820000650 A KR1019820000650 A KR 1019820000650A KR 820000650 A KR820000650 A KR 820000650A KR 830008989 A KR830008989 A KR 830008989A
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KR
South Korea
Prior art keywords
carboxylic acid
methyl
ammonium salts
acid ammonium
substituted carboxylic
Prior art date
Application number
KR1019820000650A
Other languages
Korean (ko)
Inventor
엑케르트 테오로드
Original Assignee
아놀드 자일러, 에른스트 알테르
시바-가이기 에이지
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 아놀드 자일러, 에른스트 알테르, 시바-가이기 에이지 filed Critical 아놀드 자일러, 에른스트 알테르
Publication of KR830008989A publication Critical patent/KR830008989A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

내용 없음No content

Description

치환된 카복실산 암모니움 염의 제조방법Process for preparing substituted carboxylic acid ammonium salts

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (3)

0-(2,6-디클로로아닐리노)-페닐 아세트산 또는 일반식(I)의 염과는 다른 그의 염을 N-메틸-D-글루카민 또는 그의 산부가염과 반응시킴을 특징으로 하여 일반식(I)의 N-메틸-D-글루크암모니움-[0-(2,6-디클로로아닐리노)]페닐 아세테이트를 제조하는 방법.0- (2,6-dichloroanilino) -phenyl acetic acid or a salt thereof different from the salt of formula (I) is reacted with N-methyl-D-glucamine or its acid addition salt A process for the preparation of N-methyl-D-glucanammonium- [0- (2,6-dichloroanilino)] phenyl acetate of I). 상기 식에서는 N-메틸-D-글루카민의 N-메틸-D-글루크암모니움을 양이온을 나타낸다.In the above formula Represents a cation N-methyl-D-glucammonium of N-methyl-D-glucamine. 제1항에 있어서, 각각 적어도 동몰량의 N-메틸-D-글루카민 또는 그의 산부가염이 사용함이 특징인 방법.The method of claim 1, wherein at least equimolar amounts of N-methyl-D-glucamine or acid addition salts thereof are used respectively. 제1항에 있어서, 실시예 1에 기술된 방법.The method of claim 1 wherein the method is described in Example 1. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019820000650A 1981-02-16 1982-02-15 Process for preparing substituted carboxylic acid ammonium salts KR830008989A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU83138A LU83138A1 (en) 1981-02-16 1981-02-16 TOPICAL PHARMACEUTICAL PREPARATIONS, CONTAINING SALTS OF ALKANCARBONIC ACIDS AND NEW CARBONIC ACID SALTS AND METHOD FOR THE PRODUCTION THEREOF
LU83138 1981-02-16

Publications (1)

Publication Number Publication Date
KR830008989A true KR830008989A (en) 1983-12-16

Family

ID=19729585

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019820000650A KR830008989A (en) 1981-02-16 1982-02-15 Process for preparing substituted carboxylic acid ammonium salts

Country Status (20)

Country Link
KR (1) KR830008989A (en)
AU (1) AU8049982A (en)
BE (1) BE892146R (en)
BG (1) BG37225A3 (en)
CS (1) CS227038B2 (en)
DE (1) DE3205077A1 (en)
FI (1) FI820465L (en)
FR (1) FR2499980A1 (en)
GB (1) GB2093449A (en)
GR (1) GR81389B (en)
IT (1) IT8247797A0 (en)
LU (1) LU83138A1 (en)
MA (1) MA19380A1 (en)
MC (1) MC1492A1 (en)
MT (1) MTP906B (en)
PL (1) PL136406B1 (en)
PT (1) PT74427A (en)
WO (1) WO1982002889A1 (en)
ZM (1) ZM882A1 (en)
ZW (1) ZW2782A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU83138A1 (en) * 1981-02-16 1981-09-11 T Eckert TOPICAL PHARMACEUTICAL PREPARATIONS, CONTAINING SALTS OF ALKANCARBONIC ACIDS AND NEW CARBONIC ACID SALTS AND METHOD FOR THE PRODUCTION THEREOF
AT370721B (en) * 1981-02-24 1983-04-25 Ciba Geigy Ag METHOD FOR PRODUCING NEW SALTS OF 2- (2,6-DICHLORANILINO) -PHENYLACETIC ACID, THE
ZA828453B (en) * 1981-12-08 1983-12-28 Boots Co Plc Therapeutic agents
IT1207994B (en) * 1986-01-03 1989-06-01 Therapicon Srl WATER SOLUBLE SALTS OF ANTI-INFLAMMATORY AND ANALGESIC ADAPTITY COMPOUNDS, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS.
IT1228242B (en) * 1986-11-13 1991-06-05 Ricerfarma Srl Milano DICLOFENAC SALT WITH HYDROXYETHYLPYRROLIDINE AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT
US4960799A (en) * 1988-09-13 1990-10-02 Ciba-Geigy Corporation Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use
HUT59692A (en) * 1990-11-15 1992-06-29 Puetter Medice Chem Pharm Process for producing complexes containing s/+/-phenyl-alkanoic acids and aminosugars
IT1250636B (en) * 1991-07-04 1995-04-21 Ricerche Di Schiena Del Dr Mic SALT OF DICLOFENAC, METHOD OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT.

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT290523B (en) * 1962-01-05 1971-06-11 Merck & Co Inc Process for the production of new α- (3-indolyl) -carboxylic acids
US3558690A (en) * 1965-04-08 1971-01-26 Gelgy Chemical Corp Substituted derivatives of 2-anilinophenylacetic acids and a process of preparation
CH470349A (en) * 1966-10-07 1969-03-31 Geigy Ag J R Process for the production of new substituted phenylacetic acids
US3904682A (en) * 1967-01-13 1975-09-09 Syntex Corp 2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid
NL6817965A (en) * 1967-12-20 1969-06-24
US4031243A (en) * 1975-07-03 1977-06-21 Juste, S.A. Quimico-Farmaceutica 2-(4-Isobutyl phenyl)butyric acid, salts thereof, and pharmaceutical compositions containing the same
JPS549240A (en) * 1977-06-23 1979-01-24 Asahi Chem Ind Co Ltd New derivative of phenylglycolic acid, its preparation and analgesic and antiinflammatory agent contining it as effective component
BE871335A (en) * 1978-10-18 1979-04-18 Bago Sa Labor SOLUBLE DERIVATIVES OF 2-ANILINO-ARYL-CARBOXYLIC ACIDS SUBSTITUTED BY THE ORAL ROUTE AS ANTI-INFLAMMATORY AGENTS.
DE2935776A1 (en) * 1979-09-05 1981-04-16 Theodor Prof. Dr. 4400 Münster Eckert Indomethacin, naproxen and diclofenac salts - with organic bases, esp. di:ethylamine, tri:ethanol-amine or tri:ethylamine
LU83138A1 (en) * 1981-02-16 1981-09-11 T Eckert TOPICAL PHARMACEUTICAL PREPARATIONS, CONTAINING SALTS OF ALKANCARBONIC ACIDS AND NEW CARBONIC ACID SALTS AND METHOD FOR THE PRODUCTION THEREOF
AT370721B (en) * 1981-02-24 1983-04-25 Ciba Geigy Ag METHOD FOR PRODUCING NEW SALTS OF 2- (2,6-DICHLORANILINO) -PHENYLACETIC ACID, THE

Also Published As

Publication number Publication date
CS227038B2 (en) 1984-04-16
WO1982002889A1 (en) 1982-09-02
ZM882A1 (en) 1983-04-21
MC1492A1 (en) 1983-09-12
PL136406B1 (en) 1986-02-28
AU8049982A (en) 1982-09-09
ZW2782A1 (en) 1982-09-01
MA19380A1 (en) 1982-10-01
PT74427A (en) 1982-03-01
FI820465L (en) 1982-08-17
FR2499980A1 (en) 1982-08-20
GR81389B (en) 1984-12-11
FR2499980B1 (en) 1985-03-22
GB2093449A (en) 1982-09-02
IT8247797A0 (en) 1982-02-15
DE3205077A1 (en) 1982-10-21
MTP906B (en) 1983-02-28
PL235083A1 (en) 1982-10-11
BE892146R (en) 1982-08-16
LU83138A1 (en) 1981-09-11
BG37225A3 (en) 1985-04-15

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