KR830007090A - How to prepare human adrenal cortex stimulating hormone - Google Patents

How to prepare human adrenal cortex stimulating hormone Download PDF

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Publication number
KR830007090A
KR830007090A KR1019810004772A KR810004772A KR830007090A KR 830007090 A KR830007090 A KR 830007090A KR 1019810004772 A KR1019810004772 A KR 1019810004772A KR 810004772 A KR810004772 A KR 810004772A KR 830007090 A KR830007090 A KR 830007090A
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KR
South Korea
Prior art keywords
human
producing
stimulating hormone
cell
corticosteroids
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KR1019810004772A
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Korean (ko)
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KR860001591B1 (en
Inventor
가나메 스기모도
Original Assignee
하야시바라 겡
가부시기가이샤 하야시바라 세이부쓰 가가꾸 겡뀨우죠
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Publication of KR830007090A publication Critical patent/KR830007090A/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/695—Corticotropin [ACTH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/91—Cell lines ; Processes using cell lines

Abstract

내용 없음No content

Description

인체 부신피질 자극호르몬의 제법방법How to prepare human adrenal cortex stimulating hormone

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (9)

인체 부신피질 자극호르몬의 산생능이 있는 인체로서 연유하는 림프아세포를 인체 이외의 온혈동물에 이식하고 또한 그 온혈동물의 체액의 공급을 받으면서 증식시킨 세포에서 인체 부신피질 자극호르몬을 산생시키는 것을 특징으로 하는 인체 부신피질 자극 호르몬의 제법.It is characterized by grafting lymphocytes derived from human body with the ability to produce human adrenal cortical stimulating hormone into warm-blooded animals other than the human body, and producing human adrenal cortical-stimulating hormone from the cells proliferated under the supply of fluid of the warm-blooded animal. Manufacturing method of human corticosteroids. 인체 부신피질 자극호르몬의 산생능이 있는 인체로서 연유하는 림프아세포를 인체 이외의 온혈동물에 이식하고 또한 그 온혈동물의 체액의 공급을 받으면서 증식시킨 세포에서 인체 부신피질 자극호르몬 혹은 인체 리포트로핀의 어느 것인가를 산생시키는 것을 특징으로 하는 인체 분신피질 자극 호르몬을 함유하는 복합호르몬의 제법.Lymphocytes derived from humans with acid production of human adrenal cortical stimulating hormone were transplanted into warm-blooded animals other than the human body, and proliferated under the supply of fluid from the warm-blooded animal. A method of producing a complex hormone containing human body cortical stimulating hormone, characterized in that which one is produced. 제1항 또는 제2항에 있어서 인체 림프아세포가 인체 부신피질 자극호르몬을 생산할 수 있는 인간 림프라에 세포융합 수단에 의하여 얻어지는 융합세포인 특허청구인 범위 제1항 또는 제2항에 따르는 인체 부신피질 자극 호르몬의 제법.The human adrenal cortex according to claim 1 or 2, wherein the human lymphoblasts are fusion cells obtained by means of cell fusion to human lymphocytes capable of producing human adrenal cortical stimulating hormone. Preparation of stimulating hormones. 제3항에 있어서 융합세포가 인간혐성선 증세포로서 인간 림프아의 세포융합에 의하여 얻어지는 특허청구 제3항에 따르는 인체 부신피질 자극호르몬의 제법.The method for producing human corticosteroids according to claim 3, wherein the fusion cell is a human anaerobic adenocarcinoma cell, which is obtained by cell fusion of a human lymphoid cell. 제3항에 있어서 융합세포가 인체폐암세포로서 인간 림프아의 세포융합에 의하여 얻어지는 특허청구 제3항에 따르는 인체 부신피질 자극호르몬의 제법.The method for producing human corticosteroids according to claim 3, wherein the fusion cell is a human lung cancer cell obtained by cell fusion of human lymphatic cells. 제3항에 있어서 인체 림프아가 인체 림프아구인 특허청구의 범위 제3항에 따르는 인체 부신피질 자극호르몬의 제법.The preparation method of the human adrenal cortex stimulating hormone according to claim 3, wherein the human lymphocyte is human lymphocyte. 제3항에 있어서 인체 림프아가 Namalwa, BALL-1, NALL-1, TALL-1 또는 JBL인 특허청구의 범위 제3항에 따르는 인체 부신피질 자극호르몬의 제법.The method for producing human corticosteroids according to claim 3, wherein the human lymphatic is Namalwa, BALL-1, NALL-1, TALL-1, or JBL. 제1항 또는 제2항에 있어서 증식되는 인간 림프아세포가 배소프리싱, 아트로핀, 인슐린 글루카곤, 세균성내독소, 세로토닌 또는 프로프라노롤로 된 구성중에서 하나 또는 그 이상의 멤버로서 인체 부신피질 자극호르몬의 유도체인 특허청구의 범위 제1항 또는 제2항에 따르는 인체 부신피질 자극호르몬의 제법.The human lymphoblast to be propagated according to claim 1 or 2 is a derivative of human corticosteroids as one or more members of the composition consisting of roasting frying, atropine, insulin glucagon, bacterial endotoxin, serotonin or propranolol. Method of producing a human corticosteroid hormone according to claim 1 or 2. 제1항 또는 제2항에 있어서, 인간 이외의 온혈동물인 닭, 비둘기, 개, 고양이, 원숭이, 산양, 돼지, 소, 말, 토끼, 몰모트, 쥐, 햄스터, 보통마우스, 누우드마우스인 특허청구의 범위 제1항 또는 제2항에 따르는 인체 부신피질 자극호르몬의 제법.The patent according to claim 1 or 2, which is a chicken, a pigeon, a dog, a cat, a monkey, a goat, a pig, a cow, a horse, a rabbit, a malt, a rat, a hamster, a common mouse, and a nude mouse which are warm-blooded animals other than humans. A method for producing human corticosteroids according to claim 1 or 2. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019810004772A 1980-12-13 1981-12-07 Process for the production of human adrenocorticotropic hormone KR860001591B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP55176185A JPS6045850B2 (en) 1980-12-13 1980-12-13 Production method of human adrenocorticotropic hormone
JP176185 1980-12-13

Publications (2)

Publication Number Publication Date
KR830007090A true KR830007090A (en) 1983-10-14
KR860001591B1 KR860001591B1 (en) 1986-10-13

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KR1019810004772A KR860001591B1 (en) 1980-12-13 1981-12-07 Process for the production of human adrenocorticotropic hormone

Country Status (6)

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JP (1) JPS6045850B2 (en)
KR (1) KR860001591B1 (en)
CH (1) CH652745A5 (en)
FR (1) FR2495938B1 (en)
GB (1) GB2091741B (en)
IT (1) IT1195331B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6338675A (en) * 1986-08-05 1988-02-19 Suzuki Motor Co Ltd Intake unit for multi-cylinder engine
GB9015327D0 (en) * 1990-07-12 1990-08-29 Tan Kim S Hybridomas
GB9105532D0 (en) * 1991-03-15 1991-05-01 Imutran Ltd Antibody production

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2016015B (en) * 1978-01-22 1982-05-06 Hayashibara Co Method of preparing interferon and preparations containing interferon

Also Published As

Publication number Publication date
GB2091741A (en) 1982-08-04
IT8149852A0 (en) 1981-12-07
GB2091741B (en) 1984-07-04
FR2495938B1 (en) 1985-06-21
JPS6045850B2 (en) 1985-10-12
FR2495938A1 (en) 1982-06-18
CH652745A5 (en) 1985-11-29
JPS5799526A (en) 1982-06-21
KR860001591B1 (en) 1986-10-13
IT1195331B (en) 1988-10-12

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