KR830005121A - Method for preparing 1- (acylamino-aryloxy) -2-hydroxy-3-alkynyl-aminopropane - Google Patents

Method for preparing 1- (acylamino-aryloxy) -2-hydroxy-3-alkynyl-aminopropane Download PDF

Info

Publication number
KR830005121A
KR830005121A KR1019810000750A KR810000750A KR830005121A KR 830005121 A KR830005121 A KR 830005121A KR 1019810000750 A KR1019810000750 A KR 1019810000750A KR 810000750 A KR810000750 A KR 810000750A KR 830005121 A KR830005121 A KR 830005121A
Authority
KR
South Korea
Prior art keywords
formula
carbon atoms
alkyl group
preparing
compound
Prior art date
Application number
KR1019810000750A
Other languages
Korean (ko)
Other versions
KR850000699B1 (en
Inventor
쾨페 헤르베르트
쿰머 베르너
쉬텔 헬무트
무아세픽 고코
타우네커 베르너
Original Assignee
기젤라 벨만 · 오토 핀케
쎄. 하. 베링거 존
오토 핀케
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 기젤라 벨만 · 오토 핀케, 쎄. 하. 베링거 존, 오토 핀케 filed Critical 기젤라 벨만 · 오토 핀케
Priority to KR1019810000750A priority Critical patent/KR850000699B1/en
Publication of KR830005121A publication Critical patent/KR830005121A/en
Application granted granted Critical
Publication of KR850000699B1 publication Critical patent/KR850000699B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

내용 없음No content

Description

1-(아실아미노-아릴옥시)-2-하이드록시-3-알키닐-아미노프로판의 제조방법Method for preparing 1- (acylamino-aryloxy) -2-hydroxy-3-alkynyl-aminopropane

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

Claims (1)

다음 구조식(Ⅱ)의 화합물을 다음 구조식(Ⅲ)의 아민과 반응시키거나, 다음 구조식(Ⅳ)의 옥사졸리딘유도체를 가수분해 시키거나, 다음 구조식(Ⅴ)의 화합물 또는 이의 염을 다음 구조식(Ⅵ)의 아세티디놀유도체와 반응시킴을 특징으로 하여 다음 구조식(Ⅰ)의 화합물 및 이의 생리학적으로 무독한 산부가염을 제조하는 방법.Reacting a compound of formula (II) with an amine of formula (III), or hydrolyzing an oxazolidine derivative of formula (IV), or a compound of formula (V) or a salt thereof A process for preparing the compound of formula (I) and its physiologically toxic acid addition salt, characterized in that it reacts with the acetidinol derivative of VI. 상기 구조식에서In the above structural formula R1은 탄소수 4 내지 20의 직쇄 또는 측쇄알킬그룹이고R 1 is a straight or branched chain alkyl group having 4 to 20 carbon atoms R2는 수소, 할로겐, 탄소수 1 내지 4의 알킬 또는 알콕시그룹이거나 O-위치에서의 유리원자가 결합을 가진 2가 그룹 -CH=CH-CH=CH 또는 (CH2)n(여기서 n은 3 내지 5의 정수)이고R 2 is hydrogen, halogen, an alkyl or alkoxy group having 1 to 4 carbon atoms or a divalent group having free valence bonds at the O-position —CH═CH—CH═CH or (CH 2 ) n where n is 3 to Is an integer of 5) R3는 수소 또는 탄소수 1 내지 3의 알킬그룹이고R 3 is hydrogen or an alkyl group having 1 to 3 carbon atoms R4는 탄소수 1 내지 3의 알킬그룹이거나 R3와 함께 (CH2)p(여기서 p는 4 내지 6이다)를 나타내고R 4 is an alkyl group having 1 to 3 carbon atoms or represents (CH 2 ) p (where p is 4 to 6) together with R 3 ; Z는또는 -CHOH-CH2-Hal(여기서 Hal은 할로겐임)이고Z is Or -CHOH-CH 2 -Hal, where Hal is halogen X는 -CO-, -CH2- 또는 -CH- 저급알킬그룹이다.X is -CO-, -CH 2 -or -CH- lower alkyl group. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019810000750A 1981-03-07 1981-03-07 Process for preparing 1-(acylamino-aryloxy)-2-hydroxy-3-alkinyl-aminopropanes KR850000699B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019810000750A KR850000699B1 (en) 1981-03-07 1981-03-07 Process for preparing 1-(acylamino-aryloxy)-2-hydroxy-3-alkinyl-aminopropanes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019810000750A KR850000699B1 (en) 1981-03-07 1981-03-07 Process for preparing 1-(acylamino-aryloxy)-2-hydroxy-3-alkinyl-aminopropanes

Publications (2)

Publication Number Publication Date
KR830005121A true KR830005121A (en) 1983-07-23
KR850000699B1 KR850000699B1 (en) 1985-05-15

Family

ID=19220378

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019810000750A KR850000699B1 (en) 1981-03-07 1981-03-07 Process for preparing 1-(acylamino-aryloxy)-2-hydroxy-3-alkinyl-aminopropanes

Country Status (1)

Country Link
KR (1) KR850000699B1 (en)

Also Published As

Publication number Publication date
KR850000699B1 (en) 1985-05-15

Similar Documents

Publication Publication Date Title
KR830010060A (en) Preparation of Sulfonate Derivatives
KR840004425A (en) Method for preparing N-alkyl-noscopene
KR830007686A (en) Method for preparing cephalosporin derivative
KR830005090A (en) 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaene acid
KR850004959A (en) Process for preparing aryloxy-N- (aminoalkyl) -1-pyrrolidine and piperidine carbox amide and carbothio amide
KR850002460A (en) Process for preparing carbamate compound
KR830005121A (en) Method for preparing 1- (acylamino-aryloxy) -2-hydroxy-3-alkynyl-aminopropane
KR830005225A (en) Method for preparing piperazine derivatives of deophylline
KR840002821A (en) Method for preparing N- (2,3-epoxypropylene) -N-aralkylsulfonamide derivative
KR860004051A (en) Method for preparing substituted phenylpiperazine derivatives
KR830005122A (en) Method for producing 1-aryloxy-3-alkylamino-2-propanols
KR830005120A (en) Method for preparing 1- (acylamino-aryloxy) -2-hydroxy-3-alkynyl-aminopropane
KR860006461A (en) Method for preparing a compound having antiallergic action
KR860002451A (en) Method for preparing an amide compound
KR840008004A (en) Method for preparing tropon derivatives
KR870008838A (en) Method for preparing aryl sulfone compound
KR840004105A (en) Process for preparing N, N-substituted azole carboxamide derivatives
KR840002848A (en) Method for preparing organophosphate
KR840005136A (en) Method for preparing urea compound
KR880000384A (en) Method for preparing benzoic acid derivatives
KR850004583A (en) Method for preparing phenylacetanilide derivative
KR860007215A (en) Method for preparing benzoamide derivative
KR850004746A (en) Method for preparing 1-phenylimidazolidin-2-one derivative
KR830005182A (en) Process for preparing substituted novel acetanilides
KR890002176A (en) New Cefem Compounds