KR830005089A - 퀴논 화합물의 제조방법 - Google Patents
퀴논 화합물의 제조방법 Download PDFInfo
- Publication number
- KR830005089A KR830005089A KR1019810001048A KR810001048A KR830005089A KR 830005089 A KR830005089 A KR 830005089A KR 1019810001048 A KR1019810001048 A KR 1019810001048A KR 810001048 A KR810001048 A KR 810001048A KR 830005089 A KR830005089 A KR 830005089A
- Authority
- KR
- South Korea
- Prior art keywords
- integer
- quinone compound
- compound
- preparing
- tetrahydrofuryloxy
- Prior art date
Links
- -1 quinone compound Chemical class 0.000 title claims 7
- AZQWKYJCGOJGHM-UHFFFAOYSA-N para-benzoquinone Natural products O=C1C=CC(=O)C=C1 AZQWKYJCGOJGHM-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 claims 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 125000004423 acyloxy group Chemical group 0.000 claims 1
- 125000003277 amino group Chemical group 0.000 claims 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
- 125000004093 cyano group Chemical group *C#N 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims 1
- 125000004184 methoxymethyl group Chemical group [H]C([H])([H])OC([H])([H])* 0.000 claims 1
- 230000001590 oxidative effect Effects 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 125000006239 protecting group Chemical group 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
- C07C50/28—Quinones containing groups having oxygen atoms singly bound to carbon atoms with monocyclic quinoid structure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/02—Quinones with monocyclic quinoid structure
- C07C50/04—Benzoquinones, i.e. C6H4O2
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (1)
- 다음 구조식(Ⅱ)화합물의 보호기를 제거하고, 필요하면 산화시킴을 특징으로 하는 다음 구조식(1a) 또는 (1b) 화합물 또는 그 약학적으로 사용가능한 염의 제조방법.상기 식에서,R1은 메틸 또는 메톡시이거나, 또는 두 R1이 함께 -CH=CH-CH=CH-기를 나타내며,R2는 수소, 메톡시, 메톡시메틸옥시, 2-테트라히드로피라닐옥시 또는 2-테트라히드로후릴옥시:R3는 메틸, 메톡시메틸, 2-테트라히드로피라닐 또는 2-테트라히드로후릴.X는 -CH=CH-, 또는 -C≡C-:Y1은 수소, 히드록실, 카르복실, 시아노, 아실옥시 또는 -COZ(여기에서 Z는 아미노 또는 치환된 아미노기이다).Y2는 Y1과 같거나 또는 2-테트라히드로피라닐 옥시 또는 2-테트라히드로후릴옥시.m은 0-3의 정수.n은 0-10의 정수.k는 1-3의 정수이고, k가 2 또는 3일때 n'는 1-5범위 내에서의 2 또는 3배의 임의의 변수이다.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55186622A JPS57109739A (en) | 1980-12-27 | 1980-12-27 | Quinone compound and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
KR830005089A true KR830005089A (ko) | 1983-07-23 |
KR840001717B1 KR840001717B1 (ko) | 1984-10-17 |
Family
ID=16191796
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019810001048A KR840001717B1 (ko) | 1980-12-27 | 1981-03-31 | 퀴논 화합물의 제조 방법 |
Country Status (2)
Country | Link |
---|---|
JP (1) | JPS57109739A (ko) |
KR (1) | KR840001717B1 (ko) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5910541A (ja) * | 1982-07-09 | 1984-01-20 | Takeda Chem Ind Ltd | キノン化合物 |
JPH0637388B2 (ja) * | 1986-02-17 | 1994-05-18 | 千寿製薬株式会社 | 水性液剤 |
JPH03118858U (ko) * | 1990-03-15 | 1991-12-09 | ||
EP3520860A1 (en) * | 2011-05-26 | 2019-08-07 | Indiana University Research & Technology Corporation | Quinone compounds for treating ape1 mediated diseases |
WO2014039917A1 (en) * | 2012-09-07 | 2014-03-13 | Edison Pharmaceuticals, Inc. | Benzoquinone derivatives for treating oxidative stress disorders |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3974187A (en) * | 1975-02-28 | 1976-08-10 | Wan Yieh Ping | Synthetic analogs having the activity of naturally occurring forms of coenzyme Q |
-
1980
- 1980-12-27 JP JP55186622A patent/JPS57109739A/ja active Granted
-
1981
- 1981-03-31 KR KR1019810001048A patent/KR840001717B1/ko active
Also Published As
Publication number | Publication date |
---|---|
KR840001717B1 (ko) | 1984-10-17 |
JPS6332056B2 (ko) | 1988-06-28 |
JPS57109739A (en) | 1982-07-08 |
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