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Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Title compds. (I; R = halogen, lower alkyl, fourth carbon in ring A is substituted by F, second and fourth carbon in ring B can be substituted for R group and -Coalkyl, respectively), useful as central nervous depressant and tranquillizer, were prepd. by the reaction of IX(W = free or ketalized carbonyl, Y = activated acid group) and piperazines X (n = 2, 3 integer) in the presence of acid-coupling agent at 50-150≰C, followed by reaction with a acid-addition compd.
KR7401773A1974-03-121974-03-12Method for preparing 1,4-disubstituted piperazin derivatives
KR790000200B1
(en)