KR20250009975A - 재조합 파르보바이러스 생산을 위한 조성물 및 방법 - Google Patents

재조합 파르보바이러스 생산을 위한 조성물 및 방법 Download PDF

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Publication number
KR20250009975A
KR20250009975A KR1020247037537A KR20247037537A KR20250009975A KR 20250009975 A KR20250009975 A KR 20250009975A KR 1020247037537 A KR1020247037537 A KR 1020247037537A KR 20247037537 A KR20247037537 A KR 20247037537A KR 20250009975 A KR20250009975 A KR 20250009975A
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South Korea
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aav
coding region
adenovirus
expression construct
sequence
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Korean (ko)
Inventor
치즈하오 왕
다오즈한 유
유 리유
큐이핑 첸
롱제 양
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아브너진 인코포레이티드
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
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    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14151—Methods of production or purification of viral material
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14311—Parvovirus, e.g. minute virus of mice
    • C12N2750/14322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof

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  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020247037537A 2022-05-12 2023-03-10 재조합 파르보바이러스 생산을 위한 조성물 및 방법 Pending KR20250009975A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263341201P 2022-05-12 2022-05-12
US63/341,201 2022-05-12
PCT/US2023/064152 WO2023220502A1 (en) 2022-05-12 2023-03-10 Compositions and methods for recombinant parvovirus production

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KR20250009975A true KR20250009975A (ko) 2025-01-20

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KR1020247037537A Pending KR20250009975A (ko) 2022-05-12 2023-03-10 재조합 파르보바이러스 생산을 위한 조성물 및 방법

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US (1) US20230365991A1 (https=)
EP (1) EP4522729A1 (https=)
JP (1) JP2025516599A (https=)
KR (1) KR20250009975A (https=)
CN (1) CN119487183A (https=)
AU (1) AU2023269763A1 (https=)
WO (1) WO2023220502A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024211780A1 (en) * 2023-04-07 2024-10-10 Regenxbio Inc. Compositions and methods for recombinant aav production
WO2025090962A1 (en) * 2023-10-25 2025-05-01 Regenxbio Inc. Compositions and methods for recombinant aav production
TW202548023A (zh) * 2024-03-14 2025-12-16 美商雅菲納治療公司 用於生產重組腺相關病毒的質體系統

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5139941A (en) 1985-10-31 1992-08-18 University Of Florida Research Foundation, Inc. AAV transduction vectors
US5945335A (en) * 1995-11-09 1999-08-31 Avigen, Inc. Adenovirus helper-free system for producing recombinant AAV virions lacking oncogenic sequences
US6114148C1 (en) 1996-09-20 2012-05-01 Gen Hospital Corp High level expression of proteins
DE60336736D1 (de) 2002-07-16 2011-05-26 VGX Pharmaceuticals LLC Codon-optimierte synthetische plasmide
US20130095558A1 (en) * 2011-07-19 2013-04-18 Wenlin Huang Process for producing recombinant human endostatin adenovirus
EP3870148A4 (en) * 2018-10-25 2022-11-09 Takeda Pharmaceutical Company Limited AAV TRIPLE PLASMID SYSTEM
EP3722434B1 (en) * 2019-04-12 2022-07-27 Freeline Therapeutics Limited Plasmid system
EP4085143B1 (en) * 2019-12-31 2025-08-13 Swanbio Therapeutics Limited Improved aav-abcd1 constructs and use for treatment or prevention of adrenoleukodystrophy (ald) and/or adrenomyeloneuropathy (amn)

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Publication number Publication date
US20230365991A1 (en) 2023-11-16
WO2023220502A1 (en) 2023-11-16
CN119487183A (zh) 2025-02-18
EP4522729A1 (en) 2025-03-19
AU2023269763A1 (en) 2024-10-31
JP2025516599A (ja) 2025-05-30

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