KR20240167886A - 산후 우울증의 치료를 위한 5-메톡시-n,n-다이메틸트립타민 - Google Patents

산후 우울증의 치료를 위한 5-메톡시-n,n-다이메틸트립타민 Download PDF

Info

Publication number
KR20240167886A
KR20240167886A KR1020247035761A KR20247035761A KR20240167886A KR 20240167886 A KR20240167886 A KR 20240167886A KR 1020247035761 A KR1020247035761 A KR 1020247035761A KR 20247035761 A KR20247035761 A KR 20247035761A KR 20240167886 A KR20240167886 A KR 20240167886A
Authority
KR
South Korea
Prior art keywords
dmt
meo
pharmaceutically acceptable
acceptable salt
score
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020247035761A
Other languages
English (en)
Korean (ko)
Inventor
타이스 테르바이
코너 버크
나오이즈 가프니
Original Assignee
지에이치 리서치 아일랜드 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 지에이치 리서치 아일랜드 리미티드 filed Critical 지에이치 리서치 아일랜드 리미티드
Priority claimed from PCT/EP2023/057874 external-priority patent/WO2023186827A1/en
Publication of KR20240167886A publication Critical patent/KR20240167886A/ko
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020247035761A 2022-03-27 2023-03-27 산후 우울증의 치료를 위한 5-메톡시-n,n-다이메틸트립타민 Pending KR20240167886A (ko)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
EP22000085 2022-03-27
EP22000084.8 2022-03-27
EP22000085.5 2022-03-27
EP22000084 2022-03-27
EP23154014.7 2023-01-30
EP23153996 2023-01-30
EP23154014 2023-01-30
EP23153996.6 2023-01-30
PCT/EP2023/057874 WO2023186827A1 (en) 2022-03-27 2023-03-27 5-methoxy-n,n-dimethyltryptamine for the treatment of postpartum depression

Publications (1)

Publication Number Publication Date
KR20240167886A true KR20240167886A (ko) 2024-11-28

Family

ID=93292078

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020247035761A Pending KR20240167886A (ko) 2022-03-27 2023-03-27 산후 우울증의 치료를 위한 5-메톡시-n,n-다이메틸트립타민

Country Status (8)

Country Link
US (1) US20250205200A1 (https=)
EP (1) EP4499080A1 (https=)
JP (1) JP2025510915A (https=)
KR (1) KR20240167886A (https=)
CN (1) CN119156213A (https=)
AU (1) AU2023242438A1 (https=)
CA (1) CA3255671A1 (https=)
IL (1) IL315894A (https=)

Also Published As

Publication number Publication date
AU2023242438A1 (en) 2024-11-07
EP4499080A1 (en) 2025-02-05
US20250205200A1 (en) 2025-06-26
JP2025510915A (ja) 2025-04-15
CA3255671A1 (en) 2023-10-05
IL315894A (en) 2024-11-01
CN119156213A (zh) 2024-12-17

Similar Documents

Publication Publication Date Title
WO2023186827A1 (en) 5-methoxy-n,n-dimethyltryptamine for the treatment of postpartum depression
KR20250134717A (ko) 산후 우울증의 치료에 사용하기 위한 5-meo-dmt
WO2023186826A1 (en) 5-meo-dmt for use in the treatment of postpartum depression
KR20250135903A (ko) 산후 우울증의 치료를 위한 5-메톡시-n,n-다이메틸트립타민
KR20240167886A (ko) 산후 우울증의 치료를 위한 5-메톡시-n,n-다이메틸트립타민
KR20240167885A (ko) 산후 우울증 치료에 사용하기 위한 5-meo-dmt
JP2025510911A (ja) 精神障害の治療

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

E13 Pre-grant limitation requested

Free format text: ST27 STATUS EVENT CODE: A-2-3-E10-E13-LIM-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11 Amendment of application requested

Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-NAP-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000