KR20240167885A - 산후 우울증 치료에 사용하기 위한 5-meo-dmt - Google Patents

산후 우울증 치료에 사용하기 위한 5-meo-dmt Download PDF

Info

Publication number
KR20240167885A
KR20240167885A KR1020247035760A KR20247035760A KR20240167885A KR 20240167885 A KR20240167885 A KR 20240167885A KR 1020247035760 A KR1020247035760 A KR 1020247035760A KR 20247035760 A KR20247035760 A KR 20247035760A KR 20240167885 A KR20240167885 A KR 20240167885A
Authority
KR
South Korea
Prior art keywords
dmt
meo
pharmaceutically acceptable
acceptable salt
score
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020247035760A
Other languages
English (en)
Korean (ko)
Inventor
타이스 테르바이
코너 버크
나오이즈 가프니
Original Assignee
지에이치 리서치 아일랜드 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 지에이치 리서치 아일랜드 리미티드 filed Critical 지에이치 리서치 아일랜드 리미티드
Priority claimed from PCT/EP2023/057873 external-priority patent/WO2023186826A1/en
Publication of KR20240167885A publication Critical patent/KR20240167885A/ko
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020247035760A 2022-03-27 2023-03-27 산후 우울증 치료에 사용하기 위한 5-meo-dmt Pending KR20240167885A (ko)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
EP22000083.0 2022-03-27
EP22000086 2022-03-27
EP22000086.3 2022-03-27
EP22000083 2022-03-27
EP23153995.8 2023-01-30
EP23153939 2023-01-30
EP23153995 2023-01-30
EP23153939.6 2023-01-30
PCT/EP2023/057873 WO2023186826A1 (en) 2022-03-27 2023-03-27 5-meo-dmt for use in the treatment of postpartum depression

Publications (1)

Publication Number Publication Date
KR20240167885A true KR20240167885A (ko) 2024-11-28

Family

ID=93294635

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020247035760A Pending KR20240167885A (ko) 2022-03-27 2023-03-27 산후 우울증 치료에 사용하기 위한 5-meo-dmt

Country Status (7)

Country Link
US (1) US20250221963A1 (https=)
EP (1) EP4499079A1 (https=)
JP (1) JP2025511072A (https=)
KR (1) KR20240167885A (https=)
AU (1) AU2023246547A1 (https=)
CA (1) CA3255644A1 (https=)
IL (1) IL315893A (https=)

Also Published As

Publication number Publication date
JP2025511072A (ja) 2025-04-15
AU2023246547A1 (en) 2024-11-07
CA3255644A1 (en) 2023-10-05
US20250221963A1 (en) 2025-07-10
EP4499079A1 (en) 2025-02-05
IL315893A (en) 2024-11-01

Similar Documents

Publication Publication Date Title
WO2023186826A1 (en) 5-meo-dmt for use in the treatment of postpartum depression
WO2023186827A1 (en) 5-methoxy-n,n-dimethyltryptamine for the treatment of postpartum depression
KR20250135903A (ko) 산후 우울증의 치료를 위한 5-메톡시-n,n-다이메틸트립타민
KR20250134717A (ko) 산후 우울증의 치료에 사용하기 위한 5-meo-dmt
KR20240167885A (ko) 산후 우울증 치료에 사용하기 위한 5-meo-dmt
JP2025510915A (ja) 産後うつ病の処置のための5-メトキシ-n,n-ジメチルトリプタミン
CN118946354A (zh) 用于治疗产后抑郁的5-MeO-DMT
JP2025510911A (ja) 精神障害の治療
CN118973568A (zh) 精神障碍的治疗
CN118973569A (zh) 用于治疗双相情感障碍的5-甲氧基-n,n-二甲基色胺

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

E13 Pre-grant limitation requested

Free format text: ST27 STATUS EVENT CODE: A-2-3-E10-E13-LIM-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11 Amendment of application requested

Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-NAP-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000