JP2025511072A - 産後うつ病の処置に使用するための5-MeO-DMT - Google Patents

産後うつ病の処置に使用するための5-MeO-DMT Download PDF

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Publication number
JP2025511072A
JP2025511072A JP2024557737A JP2024557737A JP2025511072A JP 2025511072 A JP2025511072 A JP 2025511072A JP 2024557737 A JP2024557737 A JP 2024557737A JP 2024557737 A JP2024557737 A JP 2024557737A JP 2025511072 A JP2025511072 A JP 2025511072A
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JP
Japan
Prior art keywords
dmt
meo
pharma
acceptable salt
score
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Pending
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JP2024557737A
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English (en)
Japanese (ja)
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JP2025511072A5 (https=
Inventor
タイス・ターヴィ
コナー・バーク
ニーシャ・ガフニー
Original Assignee
ジーエイチ・リサーチ・アイルランド・リミテッド
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Priority claimed from PCT/EP2023/057873 external-priority patent/WO2023186826A1/en
Publication of JP2025511072A publication Critical patent/JP2025511072A/ja
Publication of JP2025511072A5 publication Critical patent/JP2025511072A5/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2024557737A 2022-03-27 2023-03-27 産後うつ病の処置に使用するための5-MeO-DMT Pending JP2025511072A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
EP22000083.0 2022-03-27
EP22000086 2022-03-27
EP22000086.3 2022-03-27
EP22000083 2022-03-27
EP23153995.8 2023-01-30
EP23153939 2023-01-30
EP23153995 2023-01-30
EP23153939.6 2023-01-30
PCT/EP2023/057873 WO2023186826A1 (en) 2022-03-27 2023-03-27 5-meo-dmt for use in the treatment of postpartum depression

Publications (2)

Publication Number Publication Date
JP2025511072A true JP2025511072A (ja) 2025-04-15
JP2025511072A5 JP2025511072A5 (https=) 2026-04-07

Family

ID=93294635

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024557737A Pending JP2025511072A (ja) 2022-03-27 2023-03-27 産後うつ病の処置に使用するための5-MeO-DMT

Country Status (7)

Country Link
US (1) US20250221963A1 (https=)
EP (1) EP4499079A1 (https=)
JP (1) JP2025511072A (https=)
KR (1) KR20240167885A (https=)
AU (1) AU2023246547A1 (https=)
CA (1) CA3255644A1 (https=)
IL (1) IL315893A (https=)

Also Published As

Publication number Publication date
AU2023246547A1 (en) 2024-11-07
CA3255644A1 (en) 2023-10-05
US20250221963A1 (en) 2025-07-10
EP4499079A1 (en) 2025-02-05
IL315893A (en) 2024-11-01
KR20240167885A (ko) 2024-11-28

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