KR20240161974A - 암을 치료하기 위한 il-10을 포함하는 이중 시토카인 융합체 및 입양 세포 요법 또는 이중특이적 t-세포 연관체 - Google Patents

암을 치료하기 위한 il-10을 포함하는 이중 시토카인 융합체 및 입양 세포 요법 또는 이중특이적 t-세포 연관체 Download PDF

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KR20240161974A
KR20240161974A KR1020247023470A KR20247023470A KR20240161974A KR 20240161974 A KR20240161974 A KR 20240161974A KR 1020247023470 A KR1020247023470 A KR 1020247023470A KR 20247023470 A KR20247023470 A KR 20247023470A KR 20240161974 A KR20240161974 A KR 20240161974A
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cancer
cell
cells
antibody
car
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존 멈
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데카 바이오사이언시즈, 인크.
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
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    • C07K14/52—Cytokines; Lymphokines; Interferons
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KR1020247023470A 2021-12-16 2022-12-16 암을 치료하기 위한 il-10을 포함하는 이중 시토카인 융합체 및 입양 세포 요법 또는 이중특이적 t-세포 연관체 Pending KR20240161974A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163265521P 2021-12-16 2021-12-16
US63/265,521 2021-12-16
PCT/US2022/081862 WO2023115033A2 (en) 2021-12-16 2022-12-16 Use of dual cytokine fusion proteins comprising il-10 and adoptive cell therapies or bispecific t-cell engagers to treat cancer

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KR20240161974A true KR20240161974A (ko) 2024-11-13

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KR1020247023470A Pending KR20240161974A (ko) 2021-12-16 2022-12-16 암을 치료하기 위한 il-10을 포함하는 이중 시토카인 융합체 및 입양 세포 요법 또는 이중특이적 t-세포 연관체

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US (1) US20230210953A1 (https=)
EP (1) EP4447996A4 (https=)
JP (1) JP2024546999A (https=)
KR (1) KR20240161974A (https=)
CN (1) CN118695868A (https=)
AU (1) AU2022413694A1 (https=)
CA (1) CA3240977A1 (https=)
IL (1) IL313588A (https=)
MX (1) MX2024007404A (https=)
WO (1) WO2023115033A2 (https=)

Families Citing this family (4)

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JP7641912B2 (ja) 2019-04-19 2025-03-07 シナーキン・ファーマ・ベスローテン・フエンノートシャップ Ｉｌ１３を含む融合タンパク質
CA3186753A1 (en) * 2020-07-20 2022-01-27 John Mumm Dual cytokine fusion proteins comprising il-10
CN118900697A (zh) * 2022-02-22 2024-11-05 德卡生物科学公司 使用白细胞介素减轻双特异性t细胞接合器或嵌合抗原受体t细胞介导的细胞因子释放综合征的方法
CN117327184B (zh) * 2023-12-01 2024-03-05 赛奥斯博生物科技(北京)有限公司 一种靶向msln的嵌合抗原受体及其应用

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US5989867A (en) * 1996-09-23 1999-11-23 Knappe; Andrea DNA encoding IL-10-like homologue; related reagents
JP4793971B2 (ja) * 1999-08-09 2011-10-12 メルク パテント ゲーエムベーハー 複合サイトカイン−抗体複合体
WO2018156791A1 (en) * 2017-02-22 2018-08-30 Aleta Biotherapeutics Inc. Compositions and methods for tumor transduction
JP2022524018A (ja) * 2019-03-06 2022-04-27 デカ バイオサイエンシーズ， インコーポレイテッド Ｉｌ－１０バリアント分子ならびに炎症性疾患および腫瘍を処置する方法
CA3186753A1 (en) * 2020-07-20 2022-01-27 John Mumm Dual cytokine fusion proteins comprising il-10

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IL313588A (en) 2024-08-01
CA3240977A1 (en) 2023-06-22
CN118695868A (zh) 2024-09-24
EP4447996A4 (en) 2025-12-03
WO2023115033A3 (en) 2023-08-17
EP4447996A2 (en) 2024-10-23
MX2024007404A (es) 2024-06-28
AU2022413694A1 (en) 2024-07-11
JP2024546999A (ja) 2024-12-26
WO2023115033A2 (en) 2023-06-22
US20230210953A1 (en) 2023-07-06

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