KR20240134971A - 나노바디-약물 부가물 및 그의 용도 - Google Patents
나노바디-약물 부가물 및 그의 용도 Download PDFInfo
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- KR20240134971A KR20240134971A KR1020247027127A KR20247027127A KR20240134971A KR 20240134971 A KR20240134971 A KR 20240134971A KR 1020247027127 A KR1020247027127 A KR 1020247027127A KR 20247027127 A KR20247027127 A KR 20247027127A KR 20240134971 A KR20240134971 A KR 20240134971A
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- conjugate
- cancer
- vhh
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6839—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting material from viruses
- A61K47/6841—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting material from viruses the antibody targeting a RNA virus
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K16/20—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Zoology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263300995P | 2022-01-19 | 2022-01-19 | |
| US63/300,995 | 2022-01-19 | ||
| US202263423667P | 2022-11-08 | 2022-11-08 | |
| US63/423,667 | 2022-11-08 | ||
| PCT/US2023/060893 WO2023141500A2 (en) | 2022-01-19 | 2023-01-19 | Nanobody-drug adducts and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20240134971A true KR20240134971A (ko) | 2024-09-10 |
Family
ID=87349125
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020247027127A Pending KR20240134971A (ko) | 2022-01-19 | 2023-01-19 | 나노바디-약물 부가물 및 그의 용도 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20250144228A1 (https=) |
| EP (1) | EP4466292A2 (https=) |
| JP (1) | JP2025504481A (https=) |
| KR (1) | KR20240134971A (https=) |
| AU (1) | AU2023209439A1 (https=) |
| CA (1) | CA3249160A1 (https=) |
| IL (1) | IL314208A (https=) |
| WO (1) | WO2023141500A2 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| WO2025085675A1 (en) * | 2023-10-17 | 2025-04-24 | Mary Lynn Niedrauer | Conjugates, compositions and methods for treating rsv infection |
| WO2026011056A1 (en) | 2024-07-02 | 2026-01-08 | Cerberus Therapeutics | Compositions and methods for improving immune response |
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| US9751945B2 (en) * | 2012-04-13 | 2017-09-05 | Whitehead Institute For Biomedical Research | Sortase-modified VHH domains and uses thereof |
| EP4157883A4 (en) * | 2020-06-02 | 2024-12-04 | Children's Medical Center Corporation | NANOBODY CONJUGATES (VHH) AND THEIR USES |
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| WO2023141500A8 (en) | 2024-07-25 |
| IL314208A (en) | 2024-09-01 |
| WO2023141500A2 (en) | 2023-07-27 |
| CA3249160A1 (en) | 2023-07-27 |
| AU2023209439A1 (en) | 2024-07-18 |
| EP4466292A2 (en) | 2024-11-27 |
| WO2023141500A3 (en) | 2023-09-21 |
| JP2025504481A (ja) | 2025-02-12 |
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