KR20240134971A - 나노바디-약물 부가물 및 그의 용도 - Google Patents

나노바디-약물 부가물 및 그의 용도 Download PDF

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KR20240134971A
KR20240134971A KR1020247027127A KR20247027127A KR20240134971A KR 20240134971 A KR20240134971 A KR 20240134971A KR 1020247027127 A KR1020247027127 A KR 1020247027127A KR 20247027127 A KR20247027127 A KR 20247027127A KR 20240134971 A KR20240134971 A KR 20240134971A
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cell
conjugate
cancer
vhh
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Korean (ko)
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히데 엘. 플로그
신 류
노발리아 피셰샤
엘리샤 베르하르
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더 칠드런스 메디칼 센터 코포레이션
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Publication of KR20240134971A publication Critical patent/KR20240134971A/ko
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    • C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2833Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
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    • C07K16/30Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K2317/569Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
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    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734Complement-dependent cytotoxicity [CDC]

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KR1020247027127A 2022-01-19 2023-01-19 나노바디-약물 부가물 및 그의 용도 Pending KR20240134971A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202263300995P 2022-01-19 2022-01-19
US63/300,995 2022-01-19
US202263423667P 2022-11-08 2022-11-08
US63/423,667 2022-11-08
PCT/US2023/060893 WO2023141500A2 (en) 2022-01-19 2023-01-19 Nanobody-drug adducts and uses thereof

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KR20240134971A true KR20240134971A (ko) 2024-09-10

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