KR20240125633A - 산화질소-방출 비강 조성물 및 이의 사용 방법 - Google Patents

산화질소-방출 비강 조성물 및 이의 사용 방법 Download PDF

Info

Publication number
KR20240125633A
KR20240125633A KR1020247024094A KR20247024094A KR20240125633A KR 20240125633 A KR20240125633 A KR 20240125633A KR 1020247024094 A KR1020247024094 A KR 1020247024094A KR 20247024094 A KR20247024094 A KR 20247024094A KR 20240125633 A KR20240125633 A KR 20240125633A
Authority
KR
South Korea
Prior art keywords
composition
buffer
optionally
nitric oxide
paragraphs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020247024094A
Other languages
English (en)
Korean (ko)
Inventor
다니엘 앨버트 리쵸
캐리 브로드넥스 기어
벤자민 죠셉 몬로 프라이벳
셰일린 엘리자베스 월터
Original Assignee
엘엔에이치씨 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 엘엔에이치씨 인코포레이티드 filed Critical 엘엔에이치씨 인코포레이티드
Publication of KR20240125633A publication Critical patent/KR20240125633A/ko
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/04—Nitro compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020247024094A 2021-12-17 2022-12-16 산화질소-방출 비강 조성물 및 이의 사용 방법 Pending KR20240125633A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163290928P 2021-12-17 2021-12-17
US63/290,928 2021-12-17
PCT/US2022/081754 WO2023114971A1 (en) 2021-12-17 2022-12-16 Nitric oxide-releasing nasal compositions and methods of use thereof

Publications (1)

Publication Number Publication Date
KR20240125633A true KR20240125633A (ko) 2024-08-19

Family

ID=86773604

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020247024094A Pending KR20240125633A (ko) 2021-12-17 2022-12-16 산화질소-방출 비강 조성물 및 이의 사용 방법

Country Status (9)

Country Link
US (1) US20250049841A1 (https=)
EP (1) EP4447946A4 (https=)
JP (1) JP2024547022A (https=)
KR (1) KR20240125633A (https=)
CN (1) CN118742298A (https=)
AU (1) AU2022409833A1 (https=)
CA (1) CA3240044A1 (https=)
IL (1) IL313526A (https=)
WO (1) WO2023114971A1 (https=)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1871433B1 (en) * 2005-03-24 2009-04-22 NOLabs AB Cosmetic treatment with nitric oxide, device for performing said treatment and manufacturing method therefor
EP1888510A4 (en) * 2005-05-27 2013-01-16 Univ North Carolina NITROGEN OXIDE-RELATED PARTICLES FOR NITROGEN OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS
WO2010044875A2 (en) * 2008-10-16 2010-04-22 Novan, Inc. Nitric oxide releasing particles for oral care applications
AU2015229626B2 (en) * 2014-03-14 2021-05-20 Sanotize Research And Development Corp. Treating diseases using nitric oxide releasing solutions
WO2016160089A1 (en) * 2015-03-27 2016-10-06 Novan, Inc. Topical antiviral compositions, delivery systems, and methods of using the same
EP3177262A4 (en) * 2014-08-08 2018-04-18 Novan Inc. Topical emulsions
US11166980B2 (en) * 2016-04-13 2021-11-09 Novan, Inc. Compositions, systems, kits, and methods for treating an infection
GB2599818B (en) * 2019-06-04 2024-01-31 Thirty Respiratory Ltd Methods and compositions for generating nitric oxide and uses thereof to deliver nitric oxide via the respiratory tract
CN112791096A (zh) * 2020-12-31 2021-05-14 南京诺令生物科技有限公司 一种可自提供一氧化氮的洗鼻盐及其应用

Also Published As

Publication number Publication date
EP4447946A4 (en) 2026-01-07
IL313526A (en) 2024-08-01
AU2022409833A1 (en) 2024-06-20
WO2023114971A1 (en) 2023-06-22
US20250049841A1 (en) 2025-02-13
CA3240044A1 (en) 2023-06-22
EP4447946A1 (en) 2024-10-23
CN118742298A (zh) 2024-10-01
JP2024547022A (ja) 2024-12-26

Similar Documents

Publication Publication Date Title
US11826382B2 (en) Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses
AU2017273508A1 (en) Beta-hairpin peptidomimetic with elastase inhibitory activity and aerosol dosage forms thereof
US20220110968A1 (en) Compositions and methods to disinfect, treat and prevent microbial infections
KR20240125633A (ko) 산화질소-방출 비강 조성물 및 이의 사용 방법
US11642372B2 (en) Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses
TW201350138A (zh) 妥布黴素調配物
JP2024128022A (ja) 微生物感染を消毒、処置および予防するための組成物および方法
US12042514B2 (en) Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses
CN113244262A (zh) 一种用于预防及治疗呼吸道感染性疾病的吸入粉雾制剂
WO2021191904A1 (en) Methods for preventing and treating viral infection
WO2023021329A1 (en) Compositions and methods to disinfect, treat and prevent microbial infections
AU2022410715B2 (en) Pharmaceutical combination for the treatment of the respiratory infection caused by sars-cov-2
CN102369012B (zh) 氧化氘用于治疗病毒性呼吸道疾病的用途
US11986516B2 (en) Compositions and methods for treatment of SARS-COV-2
RU2860904C1 (ru) Способ ингибирования вируса SARS-CoV-2 в тканях легких, являющихся органом-мишенью, путем ингаляции водного раствора диэтилдитиокарбамата натрия в аэрозольной форме
US20230226136A1 (en) A synergistic formulation for management of respiratory pathogens including coronaviruses
US20240091253A1 (en) THERAPEUTIC MATERIAL WITH LOW pH AND LOW TOXICITY ACTIVE AGAINST AT LEAST ONE PATHOGEN FOR ADDRESSING PATIENTS WITH RESPIRATORY ILLNESSES
EP4380549A1 (en) Peptidase formulation for treatment of microbial infections in the upper respiratory tract
US20240000878A1 (en) Methods for treatment and/or prevention of viral infections
EP4580598A1 (en) Pharmaceutical dry powder composition and methods for treating respiratory tract infections
JP2024547022A5 (https=)
CN113244263A (zh) 一种用于预防及治疗呼吸道感染性疾病的雾化吸入制剂

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

P11 Amendment of application requested

Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-NAP-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000