CA3240044A1 - Nitric oxide-releasing nasal compositions and methods of use thereof - Google Patents

Nitric oxide-releasing nasal compositions and methods of use thereof Download PDF

Info

Publication number
CA3240044A1
CA3240044A1 CA3240044A CA3240044A CA3240044A1 CA 3240044 A1 CA3240044 A1 CA 3240044A1 CA 3240044 A CA3240044 A CA 3240044A CA 3240044 A CA3240044 A CA 3240044A CA 3240044 A1 CA3240044 A1 CA 3240044A1
Authority
CA
Canada
Prior art keywords
composition
buffer
sodium
berdazimer
nitric oxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3240044A
Other languages
English (en)
French (fr)
Inventor
Daniel Albert Riccio
Carri Brodnax Geer
Benjamin Joseph Monroe Privett
Shaylyn Elizabeth Walter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LNHC Inc
Original Assignee
LNHC Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LNHC Inc filed Critical LNHC Inc
Publication of CA3240044A1 publication Critical patent/CA3240044A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/04—Nitro compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA3240044A 2021-12-17 2022-12-16 Nitric oxide-releasing nasal compositions and methods of use thereof Pending CA3240044A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163290928P 2021-12-17 2021-12-17
US63/290,928 2021-12-17
PCT/US2022/081754 WO2023114971A1 (en) 2021-12-17 2022-12-16 Nitric oxide-releasing nasal compositions and methods of use thereof

Publications (1)

Publication Number Publication Date
CA3240044A1 true CA3240044A1 (en) 2023-06-22

Family

ID=86773604

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3240044A Pending CA3240044A1 (en) 2021-12-17 2022-12-16 Nitric oxide-releasing nasal compositions and methods of use thereof

Country Status (9)

Country Link
US (1) US20250049841A1 (https=)
EP (1) EP4447946A4 (https=)
JP (1) JP2024547022A (https=)
KR (1) KR20240125633A (https=)
CN (1) CN118742298A (https=)
AU (1) AU2022409833A1 (https=)
CA (1) CA3240044A1 (https=)
IL (1) IL313526A (https=)
WO (1) WO2023114971A1 (https=)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602006006432D1 (de) * 2005-03-24 2009-06-04 Nolabs Ab Kosmetische behandlung mit stickoxid, vorrichtung zur durchführung dieser behandlung und herstellungsverfahren dafür
ES2731298T3 (es) * 2005-05-27 2019-11-14 Univ North Carolina Chapel Hill Partículas de liberación de óxido nítrico para agentes terapéuticos de óxido nítrico y aplicaciones biomédicas
EP2334279A4 (en) * 2008-10-16 2013-03-20 Novan Inc STAIN OXIDE RELEASING PARTICLES FOR MOUTH CARE APPLICATIONS
WO2015138406A1 (en) * 2014-03-14 2015-09-17 12th Man Technologies, Inc. Treating diseases using nitric oxide releasing solutions
WO2016160089A1 (en) * 2015-03-27 2016-10-06 Novan, Inc. Topical antiviral compositions, delivery systems, and methods of using the same
CA2919733A1 (en) * 2014-08-08 2016-02-08 Novan, Inc. Topical compositions and methods of using the same
CN109310630A (zh) * 2016-04-13 2019-02-05 诺万公司 用于治疗感染的组合物、系统、试剂盒和方法
BR112021023632A2 (pt) * 2019-06-04 2022-04-19 Thirty Respiratory Ltd Métodos e composições para gerar óxido nítrico e usos do mesmo para entregar óxido nítrico através do trato respiratório
CN112791096A (zh) * 2020-12-31 2021-05-14 南京诺令生物科技有限公司 一种可自提供一氧化氮的洗鼻盐及其应用

Also Published As

Publication number Publication date
EP4447946A4 (en) 2026-01-07
US20250049841A1 (en) 2025-02-13
KR20240125633A (ko) 2024-08-19
IL313526A (en) 2024-08-01
CN118742298A (zh) 2024-10-01
EP4447946A1 (en) 2024-10-23
WO2023114971A1 (en) 2023-06-22
AU2022409833A1 (en) 2024-06-20
JP2024547022A (ja) 2024-12-26

Similar Documents

Publication Publication Date Title
BRPI0707641A2 (pt) antibiàticos nebulizados para terapia de inalaÇço
HK1249415B (en) Liquid inhalation formulation comprising rpl554
US11844823B2 (en) Beta-hairpin peptidomimetic with elastase inhibitory activity and aerosol dosage forms thereof
US20260090992A1 (en) Compositions and applications thereof
US11826382B2 (en) Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses
TW202207952A (zh) 病毒感染
US20220110968A1 (en) Compositions and methods to disinfect, treat and prevent microbial infections
ES2860098T3 (es) Composición para la aplicación nasal
US20250049841A1 (en) Nitric oxide-releasing nasal compositions and methods of use thereof
US11642372B2 (en) Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses
JP2024128022A (ja) 微生物感染を消毒、処置および予防するための組成物および方法
US20230105599A1 (en) Aqueous Formulations Containing Povidone Iodine for Effective Treatment and Prevention of Virus Infections
US12042514B2 (en) Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses
WO2023021329A1 (en) Compositions and methods to disinfect, treat and prevent microbial infections
AU2022410715B2 (en) Pharmaceutical combination for the treatment of the respiratory infection caused by sars-cov-2
US11986516B2 (en) Compositions and methods for treatment of SARS-COV-2
CN102369012B (zh) 氧化氘用于治疗病毒性呼吸道疾病的用途
US20240091253A1 (en) THERAPEUTIC MATERIAL WITH LOW pH AND LOW TOXICITY ACTIVE AGAINST AT LEAST ONE PATHOGEN FOR ADDRESSING PATIENTS WITH RESPIRATORY ILLNESSES
US20240000878A1 (en) Methods for treatment and/or prevention of viral infections
WO2023012224A1 (en) Peptidase formulation for treatment of microbial infections in the upper respiratory tract
HK40007474A (en) Liquid inhalation formulation comprising rpl554

Legal Events

Date Code Title Description
MFA Maintenance fee for application paid

Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 2ND ANNIV.) - STANDARD

Year of fee payment: 2

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-1-1-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20241213

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-1-1-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20241213

P22 Classification modified

Free format text: ST27 STATUS EVENT CODE: A-1-1-P10-P22-P110 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: CLASSIFICATION MODIFIED

Effective date: 20250331

R11 Change to the name of applicant or owner or transfer of ownership requested

Free format text: ST27 STATUS EVENT CODE: A-1-1-R10-R11-R127 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: TRANSFER RECORDAL REQUEST OR RESPONSE

Effective date: 20250722

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-1-1-W10-W00-W111 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: CORRESPONDENT DETERMINED COMPLIANT

Effective date: 20250722