KR20240116486A - 파괴된 tdp-43 결합 부위를 갖는 인간화 스타트민2 마우스 모델과 관련된 방법 및 조성물 - Google Patents

파괴된 tdp-43 결합 부위를 갖는 인간화 스타트민2 마우스 모델과 관련된 방법 및 조성물 Download PDF

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KR20240116486A
KR20240116486A KR1020247020449A KR20247020449A KR20240116486A KR 20240116486 A KR20240116486 A KR 20240116486A KR 1020247020449 A KR1020247020449 A KR 1020247020449A KR 20247020449 A KR20247020449 A KR 20247020449A KR 20240116486 A KR20240116486 A KR 20240116486A
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stmn2
sequence
tdp
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캐슬린 마리 루츠
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더 잭슨 래보라토리
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KR1020247020449A 2021-11-22 2022-11-21 파괴된 tdp-43 결합 부위를 갖는 인간화 스타트민2 마우스 모델과 관련된 방법 및 조성물 Pending KR20240116486A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163282023P 2021-11-22 2021-11-22
US63/282,023 2021-11-22
PCT/US2022/080224 WO2023092118A1 (en) 2021-11-22 2022-11-21 Methods and compositions relating to humanized stathmin2 mouse model with disrupted tdp-43 binding sites

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KR20240116486A true KR20240116486A (ko) 2024-07-29

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US (1) US20250040523A1 (https=)
EP (1) EP4436586A4 (https=)
JP (1) JP2024539458A (https=)
KR (1) KR20240116486A (https=)
CN (1) CN118284707A (https=)
IL (1) IL312770A (https=)
WO (1) WO2023092118A1 (https=)

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CN120519523A (zh) * 2025-05-21 2025-08-22 首都医科大学附属北京天坛医院 一种基于Sptlc-E260K点突变构建的ALS小鼠模型及其构建方法和用途

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US20120192298A1 (en) * 2009-07-24 2012-07-26 Sigma Aldrich Co. Llc Method for genome editing
AU2020466994A1 (en) * 2019-09-17 2022-04-21 Rutgers, The State University Of New Jersey Highly efficient DNA base editors mediated by RNA-aptamer recruitment for targeted genome modification and uses thereof

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JP2024539458A (ja) 2024-10-28
IL312770A (en) 2024-07-01
US20250040523A1 (en) 2025-02-06
EP4436586A4 (en) 2025-10-08
EP4436586A1 (en) 2024-10-02
WO2023092118A1 (en) 2023-05-25
CN118284707A (zh) 2024-07-02

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