KR20240107147A - Nk 세포 및 다중특이적 인게이저를 이용한 암의 치료 - Google Patents

Nk 세포 및 다중특이적 인게이저를 이용한 암의 치료 Download PDF

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Publication number
KR20240107147A
KR20240107147A KR1020247018559A KR20247018559A KR20240107147A KR 20240107147 A KR20240107147 A KR 20240107147A KR 1020247018559 A KR1020247018559 A KR 1020247018559A KR 20247018559 A KR20247018559 A KR 20247018559A KR 20240107147 A KR20240107147 A KR 20240107147A
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South Korea
Prior art keywords
cells
pharmaceutical composition
seq
natural killer
cell
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KR1020247018559A
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Korean (ko)
Inventor
피터 플린
제이슨 비. 리튼
토마스 제임스 파렐
헤더 카렌 래이몬
스리니바스 사이 소만치
리사 구레타즈
톨스텐 그래프
요아힘 코흐
옌스 팔
민보경
김효진
이상현
Original Assignee
아티바 바이오테라퓨틱스, 인크.
주식회사 지씨셀
아피메트 게엠베하
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Publication of KR20240107147A publication Critical patent/KR20240107147A/ko
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
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    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
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    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/283—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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KR1020247018559A 2021-11-04 2022-11-03 Nk 세포 및 다중특이적 인게이저를 이용한 암의 치료 Pending KR20240107147A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163275890P 2021-11-04 2021-11-04
US63/275,890 2021-11-04
PCT/US2022/048887 WO2023081317A2 (en) 2021-11-04 2022-11-03 Treatment of cancer with nk cells and multispecific engagers

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KR20240107147A true KR20240107147A (ko) 2024-07-08

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US (1) US20240424099A1 (https=)
EP (1) EP4426350A4 (https=)
JP (1) JP2024542159A (https=)
KR (1) KR20240107147A (https=)
CN (1) CN118613271A (https=)
AU (1) AU2022380926A1 (https=)
CA (1) CA3237016A1 (https=)
IL (1) IL312555A (https=)
WO (1) WO2023081317A2 (https=)

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WO2018124766A2 (ko) 2016-12-28 2018-07-05 주식회사 녹십자랩셀 키메라 항원 수용체 및 이를 발현하는 자연 살해 세포
EP3633029A4 (en) 2017-05-26 2021-06-09 Green Cross Lab Cell Corporation METHOD OF DEVELOPING A NATURAL KILLER CELL USING A T-CELL
US12116417B2 (en) 2017-11-14 2024-10-15 GC Cell Corporation Anti-HER2 antibody or antigen-binding fragment thereof, and chimeric antigen receptor comprising same
US11649294B2 (en) 2017-11-14 2023-05-16 GC Cell Corporation Anti-HER2 antibody or antigen-binding fragment thereof, and chimeric antigen receptor comprising same
MY199770A (en) 2018-11-14 2023-11-22 Green Cross Lab Cell Corp Method for culturing cord blood-derived natural killer cells using transformed t cells
JP2024540347A (ja) * 2021-11-09 2024-10-31 ウーゲン，インコーポレイテッド 記憶ｎｋ細胞と抗癌性二重特異性分子とによる組み合わせ癌療法

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US20240424099A1 (en) 2024-12-26
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