KR20240046524A - 미만성 거대 b-세포 림프종을 치료하기 위해 항-cd79b 면역접합체를 사용하는 방법 - Google Patents

미만성 거대 b-세포 림프종을 치료하기 위해 항-cd79b 면역접합체를 사용하는 방법 Download PDF

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KR20240046524A
KR20240046524A KR1020247006570A KR20247006570A KR20240046524A KR 20240046524 A KR20240046524 A KR 20240046524A KR 1020247006570 A KR1020247006570 A KR 1020247006570A KR 20247006570 A KR20247006570 A KR 20247006570A KR 20240046524 A KR20240046524 A KR 20240046524A
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treatment
day
rituximab
cyclophosphamide
doxorubicin
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Korean (ko)
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제이미 하루 히라타
캘빈 카 인 리
후안 진
리지아 왕
지아헹 치우
칭샹 얀
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제넨테크, 인크.
에프. 호프만-라 로슈 아게
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Publication of KR20240046524A publication Critical patent/KR20240046524A/ko
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    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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    • A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
    • A61K47/6867—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from a cell of a blood cancer
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    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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KR1020247006570A 2021-08-07 2022-08-05 미만성 거대 b-세포 림프종을 치료하기 위해 항-cd79b 면역접합체를 사용하는 방법 Pending KR20240046524A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163230735P 2021-08-07 2021-08-07
US202163230725P 2021-08-07 2021-08-07
US63/230,725 2021-08-07
US63/230,735 2021-08-07
US202163282002P 2021-11-22 2021-11-22
US63/282,002 2021-11-22
PCT/US2022/074634 WO2023019092A1 (en) 2021-08-07 2022-08-05 Methods of using anti-cd79b immunoconjugates to treat diffuse large b-cell lymphoma

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KR20240046524A true KR20240046524A (ko) 2024-04-09

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KR1020247006570A Pending KR20240046524A (ko) 2021-08-07 2022-08-05 미만성 거대 b-세포 림프종을 치료하기 위해 항-cd79b 면역접합체를 사용하는 방법

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US (2) US20240336697A1 (https=)
EP (1) EP4380978A1 (https=)
JP (1) JP2024530189A (https=)
KR (1) KR20240046524A (https=)
CN (1) CN119113101A (https=)
TW (1) TW202337499A (https=)
WO (1) WO2023019092A1 (https=)

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KR20260021689A (ko) * 2023-06-08 2026-02-13 제넨테크, 인크. 림프종 진단 및 치료 방법을 위한 대식세포 시그니처
WO2025162364A1 (zh) * 2024-02-02 2025-08-07 江苏恒瑞医药股份有限公司 抗CD79b抗体药物偶联物联合免疫治疗剂、化疗剂治疗肿瘤
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