KR20240027724A - 폴리뉴클레오티드 표적화를 위한 신규한 rna-프로그래밍 가능 시스템 - Google Patents

폴리뉴클레오티드 표적화를 위한 신규한 rna-프로그래밍 가능 시스템 Download PDF

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KR20240027724A
KR20240027724A KR1020247002706A KR20247002706A KR20240027724A KR 20240027724 A KR20240027724 A KR 20240027724A KR 1020247002706 A KR1020247002706 A KR 1020247002706A KR 20247002706 A KR20247002706 A KR 20247002706A KR 20240027724 A KR20240027724 A KR 20240027724A
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protein
tnpb
rna
sequence
lys
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비르지니우스 식스니스
타우트비다스 카르벨리스
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빌뉴스 우니베르시티
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KR1020247002706A 2021-07-02 2021-07-02 폴리뉴클레오티드 표적화를 위한 신규한 rna-프로그래밍 가능 시스템 Pending KR20240027724A (ko)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB2021/055958 WO2023275601A1 (en) 2021-07-02 2021-07-02 A novel rna-programmable system for targeting polynucleotides

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KR20240027724A true KR20240027724A (ko) 2024-03-04

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US (1) US20240368630A1 (https=)
EP (1) EP4363566A1 (https=)
JP (1) JP2024524514A (https=)
KR (1) KR20240027724A (https=)
WO (1) WO2023275601A1 (https=)

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Publication number Priority date Publication date Assignee Title
CN116355878B (zh) * 2023-02-28 2024-04-26 华中农业大学 新型TnpB编程性核酸酶及其应用
CN116355938A (zh) * 2023-03-01 2023-06-30 山东大学 基于微型RNA引导核酸酶TnpB的基因编辑载体系统及其构建方法和应用
WO2024192291A1 (en) 2023-03-15 2024-09-19 Renagade Therapeutics Management Inc. Delivery of gene editing systems and methods of use thereof
WO2024199134A1 (en) * 2023-03-27 2024-10-03 Beijing Astragenomics Technology Co., Ltd. Isolated nuclease and use thereof
AU2024335327A1 (en) 2023-09-01 2026-03-26 Renagade Therapeutics Management Inc. Gene editing systems, compositions, and methods for treatment of vexas syndrome
CN116970590B (zh) * 2023-09-22 2024-01-30 北京科芙兰德生物科学有限责任公司 小于380个氨基酸的超级迷你型基因编辑器及其应用
WO2025117544A1 (en) * 2023-11-29 2025-06-05 The Broad Institute, Inc. Engineered omega guide molecule and iscb compositions, systems, and methods of use thereof
WO2025174765A1 (en) 2024-02-12 2025-08-21 Renagade Therapeutics Management Inc. Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents

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CA3012607A1 (en) * 2015-06-18 2016-12-22 The Broad Institute Inc. Crispr enzymes and systems
EP4159856A1 (en) * 2015-06-18 2023-04-05 The Broad Institute, Inc. Novel crispr enzymes and systems
US12431216B2 (en) * 2016-08-17 2025-09-30 Broad Institute, Inc. Methods for identifying class 2 crispr-cas systems
US20230040216A1 (en) * 2019-11-19 2023-02-09 The Broad Institute, Inc. Retrotransposons and use thereof
EP4281567A4 (en) * 2021-01-25 2025-03-05 The Broad Institute Inc. REPROGRAMMABLE TNPB POLYPEPTIDES AND THEIR USE

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JP2024524514A (ja) 2024-07-05
EP4363566A1 (en) 2024-05-08
US20240368630A1 (en) 2024-11-07
WO2023275601A1 (en) 2023-01-05

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