KR20240024175A - 피부 신경섬유종의 치료에 사용하기 위한 니트록솔린 - Google Patents

피부 신경섬유종의 치료에 사용하기 위한 니트록솔린 Download PDF

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Publication number
KR20240024175A
KR20240024175A KR1020247000745A KR20247000745A KR20240024175A KR 20240024175 A KR20240024175 A KR 20240024175A KR 1020247000745 A KR1020247000745 A KR 1020247000745A KR 20247000745 A KR20247000745 A KR 20247000745A KR 20240024175 A KR20240024175 A KR 20240024175A
Authority
KR
South Korea
Prior art keywords
composition
nitroxolin
treatment
cells
administered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020247000745A
Other languages
English (en)
Korean (ko)
Inventor
데이빗 브라운
Original Assignee
힐렉스 엘티디
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 힐렉스 엘티디 filed Critical 힐렉스 엘티디
Publication of KR20240024175A publication Critical patent/KR20240024175A/ko
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020247000745A 2021-06-09 2022-06-09 피부 신경섬유종의 치료에 사용하기 위한 니트록솔린 Pending KR20240024175A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB2108224.3A GB202108224D0 (en) 2021-06-09 2021-06-09 Treatment
GB2108224.3 2021-06-09
PCT/GB2022/051442 WO2022258972A1 (en) 2021-06-09 2022-06-09 Nitroxoline for use in the treatment of cutaneous neurofibroma

Publications (1)

Publication Number Publication Date
KR20240024175A true KR20240024175A (ko) 2024-02-23

Family

ID=76838879

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020247000745A Pending KR20240024175A (ko) 2021-06-09 2022-06-09 피부 신경섬유종의 치료에 사용하기 위한 니트록솔린

Country Status (12)

Country Link
US (1) US20240261276A1 (https=)
EP (1) EP4351576A1 (https=)
JP (1) JP2024520690A (https=)
KR (1) KR20240024175A (https=)
CN (1) CN117769419A (https=)
AU (1) AU2022290019A1 (https=)
BR (1) BR112023025789A2 (https=)
CA (1) CA3221964A1 (https=)
GB (1) GB202108224D0 (https=)
IL (1) IL309177A (https=)
MX (1) MX2023014530A (https=)
WO (1) WO2022258972A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202116743D0 (en) * 2021-11-19 2022-01-05 Healx Ltd Treatment
GB202218460D0 (en) * 2022-12-08 2023-01-25 Healx Ltd Treatment

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3039822C (en) * 2016-10-14 2026-02-17 Wake Forest University Health Sciences Compositions, cell constructs, and methods of making and using the same

Also Published As

Publication number Publication date
GB202108224D0 (en) 2021-07-21
CN117769419A (zh) 2024-03-26
CA3221964A1 (en) 2022-12-15
EP4351576A1 (en) 2024-04-17
AU2022290019A1 (en) 2023-12-14
MX2023014530A (es) 2024-04-10
WO2022258972A1 (en) 2022-12-15
JP2024520690A (ja) 2024-05-24
BR112023025789A2 (pt) 2024-02-27
US20240261276A1 (en) 2024-08-08
IL309177A (en) 2024-02-01

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20240108

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20250530

Comment text: Request for Examination of Application