KR20240019244A - Apoe 및 apob 변형 지질 나노입자 조성물, 및 이의 용도 - Google Patents

Apoe 및 apob 변형 지질 나노입자 조성물, 및 이의 용도 Download PDF

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KR20240019244A
KR20240019244A KR1020247000414A KR20247000414A KR20240019244A KR 20240019244 A KR20240019244 A KR 20240019244A KR 1020247000414 A KR1020247000414 A KR 1020247000414A KR 20247000414 A KR20247000414 A KR 20247000414A KR 20240019244 A KR20240019244 A KR 20240019244A
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pharmaceutical composition
lipid
peg
polypeptide
dspe
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KR1020247000414A
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Korean (ko)
Inventor
미쉘 르블랑
그레고리 파인스타인
랜달 뉴턴 토이
비르테 놀팅
나다니엘 실버
필립 사마요아
존 에드워드 채터톤
매튜 망가니엘로
더글라스 에이. 로즈
라이언 엠. 델라니
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제너레이션 바이오 컴퍼니
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    • A61K48/0025—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid
    • A61K48/0041—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid the non-active part being polymeric
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KR1020247000414A 2021-06-07 2022-06-07 Apoe 및 apob 변형 지질 나노입자 조성물, 및 이의 용도 Pending KR20240019244A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163197881P 2021-06-07 2021-06-07
US63/197,881 2021-06-07
PCT/US2022/032510 WO2022261101A1 (en) 2021-06-07 2022-06-07 Apoe and apob modified lipid nanoparticle compositions and uses thereof

Publications (1)

Publication Number Publication Date
KR20240019244A true KR20240019244A (ko) 2024-02-14

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KR1020247000414A Pending KR20240019244A (ko) 2021-06-07 2022-06-07 Apoe 및 apob 변형 지질 나노입자 조성물, 및 이의 용도

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US (1) US20240299580A1 (https=)
EP (1) EP4351533A4 (https=)
JP (1) JP2024520756A (https=)
KR (1) KR20240019244A (https=)
CN (1) CN117897143A (https=)
AU (1) AU2022288618A1 (https=)
CA (1) CA3221454A1 (https=)
IL (1) IL308928A (https=)
WO (1) WO2022261101A1 (https=)

Families Citing this family (15)

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WO2024119103A1 (en) 2022-12-01 2024-06-06 Generation Bio Co. Lipid nanoparticles comprising nucleic acids and lipid-anchored polymers
EP4626400A1 (en) 2022-12-01 2025-10-08 Generation Bio Co. Novel polyglycerol-conjugated lipids and lipid nanoparticle compositions comprising the same
WO2024119074A1 (en) 2022-12-01 2024-06-06 Generation Bio Co. Stealth lipid nanoparticle compositions for cell targeting
AU2023406303A1 (en) 2022-12-01 2025-05-29 Generation Bio Co. Lipid nanoparticles comprising nucleic acids, ionizable lipids, sterols, lipid anchored polymers and helper lipids, their uses
US20240226133A1 (en) * 2023-01-09 2024-07-11 Claudia Chimisso Dos Santos Microrna-based particle for the treatment of dysregulated immune response
WO2024200820A1 (en) 2023-03-30 2024-10-03 Ose Immunotherapeutics Method of synthesis of targeted lipid nanoparticle and uses thereof
EP4687991A1 (en) 2023-03-30 2026-02-11 Ose Immunotherapeutics Lipid-based nanoparticle targeted at activated immune cells for the expression of immune cell enhancing molecule and use thereof
WO2024226779A1 (en) * 2023-04-26 2024-10-31 Saliogen Therapeutics, Inc. Lipid nanoparticle (lnp) formulations
IT202300015291A1 (it) * 2023-07-20 2025-01-20 Fond Riccardo Terzi E Silvio Albini Sistema di rilascio comprendente nanoparticelle lipidiche o polimeriche comprendenti ormoni tiroidei
WO2025052180A2 (en) 2023-09-07 2025-03-13 Axelyf ehf. Lipids and lipid nanoparticles
WO2025230906A1 (en) * 2024-04-29 2025-11-06 Saliogen Therapeutics, Inc. Lipid nanoparticle (lnp) formulations
WO2026003582A2 (en) 2024-06-27 2026-01-02 Axelyf ehf. Lipids and lipid nanoparticles
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