KR20230150833A - 세포 배양 방법 - Google Patents

세포 배양 방법 Download PDF

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KR20230150833A
KR20230150833A KR1020237032289A KR20237032289A KR20230150833A KR 20230150833 A KR20230150833 A KR 20230150833A KR 1020237032289 A KR1020237032289 A KR 1020237032289A KR 20237032289 A KR20237032289 A KR 20237032289A KR 20230150833 A KR20230150833 A KR 20230150833A
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cells
medium
fold
concentration
mosm
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Korean (ko)
Inventor
수만 쿠마르 보드날라
요긴 파텔
니콜라스 피. 레스티포
로버트 랭글런드 에일
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라이엘 이뮤노파마, 인크.
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A61K39/4611
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/30Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31Chimeric antigen receptors [CAR]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • A61K40/4202Receptors, cell surface antigens or cell surface determinants
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • A61K40/4202Receptors, cell surface antigens or cell surface determinants
    • A61K40/421Immunoglobulin superfamily
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N2501/727Kinases (EC 2.7.)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
KR1020237032289A 2021-02-25 2022-02-24 세포 배양 방법 Pending KR20230150833A (ko)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US202163153920P 2021-02-25 2021-02-25
US202163153905P 2021-02-25 2021-02-25
US63/153,905 2021-02-25
US63/153,920 2021-02-25
US202163165042P 2021-03-23 2021-03-23
US202163165021P 2021-03-23 2021-03-23
US63/165,021 2021-03-23
US63/165,042 2021-03-23
US202163167606P 2021-03-29 2021-03-29
US202163167608P 2021-03-29 2021-03-29
US63/167,608 2021-03-29
US63/167,606 2021-03-29
US202163181224P 2021-04-28 2021-04-28
US63/181,224 2021-04-28
US202163273141P 2021-10-28 2021-10-28
US63/273,141 2021-10-28
PCT/US2022/017774 WO2022182915A1 (en) 2021-02-25 2022-02-24 Methods for culturing cells

Publications (1)

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KR20230150833A true KR20230150833A (ko) 2023-10-31

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US (1) US20240228957A9 (https=)
EP (1) EP4298208A1 (https=)
JP (1) JP2024509095A (https=)
KR (1) KR20230150833A (https=)
AU (1) AU2022226660A1 (https=)
CA (1) CA3172318A1 (https=)
IL (1) IL304349A (https=)
TW (1) TW202302842A (https=)
WO (1) WO2022182915A1 (https=)

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WO2021189008A1 (en) 2020-03-20 2021-09-23 Lyell Immunopharma, Inc. Novel recombinant cell surface markers
CA3158133A1 (en) 2020-04-28 2021-11-04 Lyell Immunopharma, Inc. Methods for culturing cells
US12144827B2 (en) 2021-02-25 2024-11-19 Lyell Immunopharma, Inc. ROR1 targeting chimeric antigen receptor
IL312204A (en) * 2021-10-28 2024-06-01 Lyell Immunopharma Inc Methods for culturing cells expressing ror1-binding protein
NL2035656B1 (en) * 2023-08-23 2025-03-06 Cimaas B V Method of preparing a solution of mitotically suppressed cells
CN118165933B (zh) * 2024-05-14 2024-07-16 成都美杰赛尔生物科技有限公司 组合物、提高cd39-cd69-t细胞比例的方法

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IL86278A (en) 1988-05-04 2003-06-24 Yeda Res & Dev Endowing cells with antibody specificity using chimeric t cell receptor
WO2015157636A1 (en) 2014-04-10 2015-10-15 H. Lee Moffitt Cancer Center And Research Institute, Inc. Enhanced expansion of tumor-infiltrating lymphocytes for adoptive cell therapy
GB2592821B (en) 2015-07-31 2022-01-12 Univ Minnesota Modified cells and methods of therapy
MX2018004721A (es) 2015-10-23 2018-07-06 Eureka Therapeutics Inc Construcciones quimericas anticuerpo/receptor de celulas t y usos de las mismas.
TWI788307B (zh) 2016-10-31 2023-01-01 美商艾歐凡斯生物治療公司 用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞
MX2019007963A (es) 2017-01-06 2019-10-21 Iovance Biotherapeutics Inc Expansion de linfocitos infiltrantes de tumor (til) con agonistas de la superfamilia de recptor de factor de necrosis tumoral (tnfrsf) y combinaciones terapeuticas de til- y agonistas de tnfrsf.
JOP20190224A1 (ar) 2017-03-29 2019-09-26 Iovance Biotherapeutics Inc عمليات من أجل إنتاج الخلايا اللمفاوية المرتشحة للأورام واستخداماتها في العلاج المناعي
JP7538601B2 (ja) 2017-04-26 2024-08-22 ユーリカ セラピューティックス, インコーポレイテッド キメラ活性化受容体及びキメラ刺激受容体を発現する細胞並びにその使用
CA3090795A1 (en) 2018-02-13 2019-08-22 Iovance Biotherapeutics, Inc. Expansion of tumor infiltrating lymphocytes (tils) with adenosine a2a receptor antagonists and therapeutic combinations of tils and adenosine a2a receptor antagonists
WO2019217753A1 (en) 2018-05-10 2019-11-14 Iovance Biotherapeutics, Inc. Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
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BR112022011795A2 (pt) 2019-12-20 2022-08-30 Instil Bio Uk Ltd Métodos para preparar e isolar uma população terapêutica de linfócitos e para tratar câncer em um indivíduo, população terapêutica de linfócitos, bolsa criopreservada, recipiente flexível, e, sistema para extração de linfócitos
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AU2022226660A9 (en) 2024-05-16
AU2022226660A1 (en) 2023-07-27
US20240132840A1 (en) 2024-04-25
CA3172318A1 (en) 2022-09-01
IL304349A (en) 2023-09-01
EP4298208A1 (en) 2024-01-03
TW202302842A (zh) 2023-01-16
US20240228957A9 (en) 2024-07-11
JP2024509095A (ja) 2024-02-29
WO2022182915A1 (en) 2022-09-01

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