KR20230140791A - Cell management service system and method thereof - Google Patents

Abstract

The present invention relates to a cell management service system and method. The cell management service system according to the present invention includes a cell culture control device that collects and transmits measurement data regarding cell culture, and a cell culture control device that generates and transmits requirement data for cell management. It includes a service server that generates cell management data using the user terminal and requirement data, measurement data, and pre-stored reference data transmitted from the user terminal, and transmits the generated cell management data to the cell culture control device and the administrator terminal. . According to the present invention, multiple cell cultivators can be shared and used by multiple users, and can be managed more efficiently while satisfying the different cell management requirements of multiple users.

Description

Cell management service system and method {CELL MANAGEMENT SERVICE SYSTEM AND METHOD THEREOF}

The present invention relates to a cell management service system and method, and more specifically, to a cell management service system and method that can manage a plurality of cell cultivators while sharing them.

In general, cell culture involves aseptically removing tissue pieces from multicellular organisms, providing them with nutrients, and culturing and proliferating them in a container. For cell culture, a culture chamber provides a certain space for cells to be cultured, and nutrients for the cells. Culture medium or various gases that supply are required. In particular, culture media and various gases are injected into the culture chamber and used for cell culture, and then exchanged at appropriate intervals to keep the cell tissue in a fresh state.

This cell culture is a process of placing cells in a physiological environment, and includes stimulation treatment to change their characteristics and curing treatment to prevent their characteristics from changing. In other words, cell culture is a field that creates cells for a specific purpose by changing the characteristics by adding growth factors and engineered genes or viruses. There is also a simple amplification culture for use in cell therapy or cultured meat, pharmaceutical production, etc. It can be used in a variety of fields such as plant breeding, alternative meat, or feed production.

In this way, large-scale amplified curing facilities are required for curing for use in treatment or producing small quantities of substitute meat and synthetic meat, but the manpower and systems that manage them are rarely built on a small scale, so they can meet the needs of consumers in a variety of ways. There was a problem that couldn't be done.

Accordingly, there was a problem of having to bear relatively high costs for small-scale activities required for research cells.

In order to solve the above problems, a system to dramatically reduce curing costs and satisfy the diverse needs of consumers by allowing multiple users to share and manage devices, equipment, various technologies, knowledge, and software for cell curing. This is being demanded.

Korean Patent Publication No. 2014-0014494

The present invention provides a cell management service system and method that allows multiple cell culture devices to be shared and used by multiple users and can be managed more efficiently while satisfying the different cell management requirements of multiple users. The purpose is to

The problems of the present invention are not limited to the problems mentioned above, and other problems not mentioned will be clearly understood by those skilled in the art from the description below.

A cell management service system according to an embodiment of the present invention to solve the above technical problems includes a cell culture control device that collects and transmits measurement data on cell culture, and a user terminal that generates and transmits requirement data for cell management. And a service server that generates cell management data using the requirement data transmitted from the user terminal, the measurement data, and pre-stored reference data, and transmits the generated cell management data to the cell culture control device and the manager terminal. Includes.

The service server stores a plurality of manager data according to the type of cell management, searches for manager data matching the generated cell management data among the stored plurality of manager data, and sends the manager terminal corresponding to the searched manager data. The cell management data can be transmitted.

The type of cell management may include at least one of providing cells, maintaining, repairing, disinfecting, cleaning, replacing consumables, managing the cell culture environment, determining cell status, collecting cells, transporting and storing the cells.

The service server may calculate management cost data using the requirement data and the cell management data, and transmit the calculated management cost data to the user terminal and the manager terminal.

The service server may reflect at least one of cell management time, cell management type, and management difficulty to calculate the management cost data.

The service server can use blockchain coins to make payment for the management cost data.

The requirement data may include data on a shared space accessible by an administrator and a non-shareable space accessible by a robot.

Meanwhile, a cell management service method performed by a service server supporting a cell management service through communication with a cell culture control device, a user terminal, and an administrator terminal according to an embodiment of the present invention is performed from the cell culture control device and the user terminal. Receiving measurement data related to cell culture and requirement data for cell management, respectively, generating cell management data using the transmitted requirement data, the measurement data, and pre-stored reference data, and generating cells It includes transmitting management data to the cell culture control device and the manager terminal.

The cell management service method according to an embodiment of the present invention further includes the step of storing a plurality of manager data according to the type of cell management, and transmitting the generated cell management data to the cell culture control device and the manager terminal. The step may include searching for manager data matching the generated cell management data among the plurality of stored manager data, and transmitting the cell management data to a manager terminal corresponding to the searched manager data.

The type of cell management may include at least one of providing cells, maintaining, repairing, disinfecting, cleaning, replacing consumables, managing the cell culture environment, determining cell status, collecting cells, transporting and storing the cells.

The cell management service method according to an embodiment of the present invention includes calculating management cost data using the requirement data and the cell management data and transmitting the calculated management cost data to the user terminal and the manager terminal. It may further include.

To calculate the management cost data, at least one of cell management time, type of cell management, and management difficulty may be reflected.

The cell management service method according to an embodiment of the present invention may further include the step of ensuring that payment for the management cost data is made using a blockchain coin.

The requirement data may include data on a shared space accessible by an administrator and a non-shareable space accessible by a robot.

According to the cell management service system and method according to an embodiment of the present invention, a plurality of cell cultivators can be shared and used by multiple users, and more efficiently while satisfying the different cell management requirements of multiple users. It has the advantage of being manageable.

In other words, by allowing multiple cell cultivators to be shared with different users and pay for management costs, users' diverse cell cultivation and management needs are met, management costs for shared personnel and equipment are lowered, and each user's needs are met. It has the advantage of being able to operate different culture types and scales.

In this way, multiple users can share and manage various technologies, knowledge, and software, such as group purchasing of devices or equipment for cell culture, culture medium, supply or replacement of consumables, action after checking the culture status, and transportation to maintain activity. This has the advantage of dramatically reducing cultivation costs and satisfying the diverse needs of multiple users.

In addition, as the user or manager requesting management has more experience, curing results, which can vary depending on the cell, can be further improved to meet demand, and the cost to pay is reduced accordingly, increasing the level of curing skills and knowledge of the user. The higher the level, the lower the overall cost, which has the advantage of providing social motivation to acquire curing technology.

The effects according to the present invention are not limited to the contents exemplified above, and further various effects are included in the present specification.

Figure 1 is a configuration diagram showing a cell management service system according to an embodiment of the present invention.
FIG. 2 is a detailed configuration diagram of the cell cultivator and cell culture control device shown in FIG. 1.
Figure 3 is an operational flowchart showing a cell management service process according to an embodiment of the present invention.

The advantages and features of the present invention and methods for achieving them will become clear by referring to the embodiments described in detail below along with the accompanying drawings.

However, the present invention is not limited to the embodiments disclosed below and will be implemented in various different forms.

The examples herein are provided to ensure that the disclosure of the present invention is complete and to fully inform those skilled in the art of the scope of the invention.

And the present invention is only defined by the scope of the claims.

Accordingly, in some embodiments, well-known components, well-known operations and well-known techniques are not specifically described in order to avoid ambiguous interpretation of the present invention.

In addition, the same reference numerals refer to the same elements throughout the specification, and the terms used (mentioned) in the specification are for explaining embodiments and are not intended to limit the present invention.

In this specification, the singular also includes the plural unless specifically stated in the phrase, and elements and operations referred to as 'including (or, including)' do not exclude the presence or addition of one or more other elements and operations. .

Unless otherwise defined, all terms (including technical and scientific terms) used in this specification may be used with meanings that can be commonly understood by those skilled in the art to which the present invention pertains.

Additionally, terms defined in commonly used dictionaries are not interpreted ideally or excessively unless they are defined.

Hereinafter, preferred embodiments of the present invention will be described with reference to the attached drawings.

FIG. 1 is a configuration diagram showing a cell management service system according to an embodiment of the present invention, and FIG. 2 is a detailed configuration diagram of the cell cultivator and cell culture control device shown in FIG. 1.

As shown in FIGS. 1 and 2, the cell management service system 1 includes a cell culture control device 100, a user terminal 200, an administrator terminal 300, and a service server 400.

The cell culture control device 100 can control a plurality of cell cultivators 50 and may be composed of a plurality of cell culture devices 50 . The plurality of cell cultivators 50 may include a chamber 51 having a certain space therein for culturing cells, a cell culture container 52 accommodated inside the chamber 51, and the like. The interior of the cell incubator 50 is optimized for culturing cells, maintains an environment suitable for cell culture, differentiation, or curing, and cell growth, and includes a device 120 for irradiating light to cells, and a device for photographing cells. The device 110a, a device for supplying culture medium to cells, a device for supplying various gases, a device for controlling temperature, or a device for suppressing contamination may be installed.

The cell culture control device 100 may include a collection unit 110, a communication unit 130, and a control unit 150.

The collection unit 110 may collect measurement data related to cell culture.

In more detail, the collection unit 110 may collect measurement data including first measurement data about cells, second measurement data about culture conditions, and third measurement data about culture operations. Here, the first measurement data is a cell image representing the culture state of the cell, and may include parameters such as the number of cells, cell size, cell shape, cell movement distance, number of cell divisions, or cell brightness.

The collection unit 110 for this may include an image acquisition means for acquiring a video image of the cell and an image editing means for editing the video image of the cell into a desired form. Image acquisition means are generally means for observing cell video images, such as applying a phase contrast microscope using direct illumination, a CCD (Charge Coupled Device) camera using indirect illumination and a reflector, a CMOS (Complementary Metal Oxide Semiconductor) sensor, or A microscope for cell observation can be applied. Cell video images can be easily acquired using such a microscope, and at this time, the cell video images can be in the form of photos or videos. The image editing means can enlarge, reduce, move, rotate, change lighting or background settings of the acquired cell image image so that the user can easily observe the acquired cell image image.

The collection unit 110 may collect second measurement data on culture conditions such as temperature, acidity (pH), osmotic pressure, pressure, or turbidity, which is environmental information inside the cell culture device 50, and electrical conductivity or centrifugal force, etc. Likewise, third measurement data on the operation of the device for operating the cell culture device 50 can be continuously collected.

The communication unit 130 may exchange various information with a plurality of cell cultivators 50, the user terminal 200, the administrator terminal 300, and the service server 400 through the communication network 10.

Here, the communication network 10 includes a Local Area Network (LAN), a Metropolitan Area Network (MAN), a Wide Area Network (WAN), the Internet, and 3G/4G/5G (generation). ) It may include various data communication networks, including mobile communication networks, Wi-Fi, WIBRO (Wireless Broadband Internet), or LTE (Long Term Evolution), etc., regardless of whether wired or wireless, and it does not matter which communication method is used. does not exist.

The control unit 150 may generally control the operation of the cell culture control device 100. For example, when cell management data is received from the service server 400, which will be described below, cell management is performed according to the cell management data. For example, if the cell management data is a measure to reduce the intensity of light irradiated to cells, the control unit 150 may control the operation of the device 120 for irradiating light to cells to reduce the intensity of light irradiated to cells.

The user terminal 200 consists of a plurality of devices, including a personal computer (PC), a smart phone, a tablet PC, a personal digital assistant (PDA), or a web pad. ), etc., it may be a terminal equipped with a memory means and equipped with a microprocessor to have computing capabilities.

The user terminal 200 is a terminal used by a user who requests cell management, such as cell culture or curing, and may be installed with an application or program that provides cell management services. When a user executes an application or program installed on the user terminal 200, a screen is created where requirement data for cell management can be entered, allowing the user to request desired cell management.

That is, the user terminal 200 may generate requirement data related to cell management according to the user's request and transmit it to the service server 400. At this time, the requirement data for cell management may include requests for cell management, such as provision, care, manipulation, observation, judgment, collection, re-dispatch, transport, or storage of cells.

The user terminal 200 may receive cell management data, including cell management history, from the service server 400 to determine the cell management status or the management status of the cell incubator 50. Here, the cell management data may include data managed by manipulating the devices in the cell cultivator 100, such as device maintenance, repair, disinfection, cleaning, and replacement of consumables, or may include action data regarding cell culture.

The administrator terminal 300 is a terminal used by an administrator who performs management by a user who has requested cell management, and an application or program that provides cell management services may be installed. Here, the manager may include a device manufacturer/importer or lessor responsible for maintenance of the cell culture device or cell culture control device, and may include a manager who temporarily or continuously manages the culture at the request of the user. Additionally, managers may include providers who provide clean rooms, biological safety management facilities, secure office or home spaces, and observers who observe cell conditions such as cell density, size, and shape may be included as managers. Of course.

The manager terminal 300 can receive cell management data from the service server 400, and the manager who confirms the received cell management data provides cells, maintains, repairs, disinfects, cleans, replaces consumables, and cultivates cells. Cell management may be performed, including management of the environment, determination of cell status, cell collection, transportation, or storage.

The service server 400 can exchange various information with a plurality of cell culture control devices 100, user terminal 200, and administrator terminal 300 through the communication network 10.

More specifically, the service server 400 may store reference data regarding cell culture. Here, the service server 400 can receive and store reference data on cell culture from an external reference database, and collect data provided by external reference databases such as cell culture specialized organizations to provide standards for management of cell culture. It can be used as data.

The service server 400 may store a plurality of manager data according to the type of cell management. For example, the plurality of manager data may include data about a first manager responsible for first management performing maintenance, repair, etc. of the device, data about a second manager responsible for second management performing disinfection, cleaning, etc., It may include data on a third manager in charge of third management performing consumable exchange, and data on a fourth manager in charge of fourth management in checking cell culture status and generating action data.

In this way, the service server 400 can store data about the manager in charge according to the type of cell management.

The service server 400 may receive requirement data related to cell management from the user terminal 200, and generate cell management data using the results of analysis by comparing the received requirement data and measurement data with reference data. there is. Here, the requirement data may include environmental requirements such as temperature/humidity/carbon dioxide, etc. within the cell incubator 50, operation requirements such as intensity of irradiated light, irradiation time, etc., requests for matters requiring management, etc. may include.

And the requirement data may include data about a shared space accessible by the administrator, a non-shareable space accessible by the administrator, and a non-shareable space accessible by the robot. In other words, space that can be shared by multiple users and space that cannot be shared are monitored to monitor the access or manipulation of users or robots, and observation information on the state of cells can be collected by administrators who are allowed to view them through the Internet. make it possible

Additionally, the service server 400 may search for manager data matching the generated cell management data among the plurality of stored manager data, and transmit the cell management data to the manager terminal 300 corresponding to the searched manager data.

In more detail, the service server 400 may detect the type of cell management corresponding to the generated cell management data among the plurality of stored manager data and search for manager data matching the detected type of cell management. Then, the service server 400 may transmit cell management data to the manager terminal 300 corresponding to the searched manager data.

For example, when the service server 400 receives requirement data for determining the state of cells from the user terminal 200, the cell video images collected at regular intervals are compared and analyzed with pre-stored reference video images to measure It is possible to determine whether the target cell is differentiated normally. The video image of the target cell is recognized through an image processing program, and then compared with a reference video image stored in advance according to the time elapsed after differentiation or measurement was started, the normality of the target cell is determined. You can decide whether to differentiate or not.

If it is determined that the cell to be measured is normally differentiated, the service server 400 stores the operation information of the cell culture device 50, the video image of the cell to be measured, and the differentiation result, and the result information is stored in the cell culture control device 100. ), can be controlled to be transmitted to the user terminal 200 and the administrator terminal 300.

Meanwhile, if it is not determined that the cell to be measured is normally differentiated, the service server 400 controls the abnormal video image to be transmitted to the cell culture control device 100, the user terminal 200, and the administrator terminal 300. And, cell management data can be generated to take action on measurement target cells that have abnormalities. Then, the service server 400 may detect cell collection, which is a type of cell management corresponding to the generated cell management data, among the plurality of stored manager data, and search for manager data that performs the detected cell collection. Then, the service server 400 can transmit cell management data to the terminal 300 of the manager performing cell collection to quickly perform cell collection. At this time, when an abnormality occurs in a cell, the service server 400 can control the output of a warning message or warning sound to inform the user terminal 200 and the administrator terminal 300 that an abnormality has occurred. For example, the service server 400 can automatically warn when a serious abnormality occurs in the cell, such as temperature, acidity, osmotic pressure, image, etc., and matters that require automatic adjustment are pre-entered in each cell culture control device 100. It can be configured to automatically adjust as required.

In addition, the service server 400 generates action data that can control the environment inside the cell culture device 50 as cell management data to control the cell culture control device 100, the user terminal 200, and the administrator terminal 300. can be provided to. That is, the service server 400 provides cell management data that includes at least one of the strength, frequency, time, and pattern of different magnetic fields in order to control the light irradiation device or the magnetic field irradiation device provided inside the cell incubator 50. Can be generated and provided to the cell culture control device 100, the user terminal 200, and the administrator terminal 300.

In this way, the service server 400 generates cell management data that can correct abnormalities occurring in the cell culture device 50 or during the cell management process, and uses the cell culture control device 100, the user terminal 200, and the administrator terminal ( 300) can be controlled to be transmitted. Here, the cell management data may include operational data for operating the cell culture device. For example, the service server 400 generates operational data for controlling the intensity of light irradiated for cell culture, irradiation time, etc., and transmits it to the cell culture control device 100, the user terminal 200, and the administrator terminal 300. It can be controlled as much as possible, and details about the operation of the cell culture device can be controlled to be transmitted to the cell culture control device 100, the user terminal 200, and the administrator terminal 300.

And the final verification items of cell management based on the premise of management history, safety management, and delivery verification include the security of dangerous substance input fraud, that is, the security of maintaining management records and location records, and the security of active maintenance verification of transportation records and visual inspection. . Additionally, there is numerical authentication security for microscopic findings and density meters, and identity verification security for storage, transportation, and comparison of genetic findings. In addition, there is security against contamination by bacteria, security against mixing with animal ingredients, security against mixing with other people and heterogeneous cells, and delivery. These include external safety and security of the container and storage state maintenance security.

In this way, cell management data may include information necessary to manage cells, such as operation, maintenance, repair, disinfection, cleaning, and replacement of consumables, and may require operator manipulation, such as maintenance of the cell incubator or replacement of consumables. In the case of management, the relevant cell management data can be transmitted to the manager terminal 300 and the manager can control it to be performed directly.

Meanwhile, the service server 400 can receive analysis results by comparing the collected measurement data and reference data from an external analysis server, and generate cell management data based on the received analysis results. At this time, the external analysis server may be a server operated by an expert in cell culture or a server operated by a professional analysis program or artificial intelligence algorithm.

In this way, a network is formed between the cell culture control device 100, the user terminal 200, the administrator terminal 300, and the service server 400 to monitor and manage the cell management process in real time to manage cell culture more efficiently. can do.

At this time, when there are a plurality of user terminals 200, requirement data can be received for each of the plurality of user terminals 200, and different cell management data can be generated in response to the received requirement data, thereby managing different cells. It has the advantage of satisfying the diverse needs of users who have requirements for.

The service server 400 may calculate management cost data using requirement data and cell management data, and transmit the calculated management cost data to the user terminal 200 and the manager terminal 300. At this time, the service server 400 may reflect at least one of cell management time, cell management type, and management difficulty to calculate management cost data.

More specifically, the service server 400 can determine whether to use the regular payment service according to the requirement data, and can calculate management cost data differently depending on the difficulty of using and managing the regular payment service. For example, when using a regular payment service, management cost data is calculated taking into account the number of users using the regular payment service, and when using analysis results received from an external analysis server, it is managed by dividing it into a separate amount. Cost data can be calculated, and if direct manipulation by the manager is required in the management of cell culture, management cost data can be calculated by setting the manager's cost separately.

In this way, the management cost to be paid varies depending on the type and difficulty of cell management entrusted to each functional location, and each user pays for the entrusted cell management, thereby meeting the needs of various cell care and research. , lowers the cost of shared management personnel and devices, and enables the operation of research types and scales with different needs for each user. In addition, the indirect management function through the Internet allows users and managers to share situational awareness and knowledge about cultivation.

At this time, the service server 400 can use blockchain coins to make payment for management cost data. Here, blockchain uses a peer-to-peer (P2P) network, rather than the traditional method of storing specific information on a specific central server, to distribute and record information to all users and manage it jointly, thereby improving the stability of information. , refers to technology that ensures reliability, integrity, and transparency. In a blockchain, information is connected into blocks and stored on multiple distributed servers, and a process of frequently comparing and checking whether the information on each server matches is carried out. This process is continuously carried out for servers participating in the blockchain. Therefore, the reliability and stability of information have the advantage of being relatively higher than existing centralized networks.

In the following, a cell management service method according to an embodiment of the present invention will be described.

Figure 3 shows an operational flowchart showing a cell management service process according to an embodiment of the present invention.

Referring to FIG. 3, the service server may receive measurement data on cell culture and requirement data for cell management from the cell culture control device and the user terminal, respectively (S300).

More specifically, the cell culture control device collects measurement data including first measurement data about cells, second measurement data about culture conditions, and third measurement data about culture operation, and sends the collected measurement data to the service server. can be transmitted to. Here, the first measurement data is a cell image representing the culture state of the cell and may include parameters such as the number of cells, cell size, cell shape, cell movement distance, number of cell divisions, or cell brightness, and the second measurement data is It may be data about culture conditions such as temperature, acidity (pH), osmotic pressure, pressure, or turbidity, which is environmental information inside the cell culture device 50, and the third measurement data may be data about the cell culture device 50, such as electrical conductivity or centrifugal force. It may contain data about the operation of the device to operate.

The user terminal may generate requirement data related to cell management according to the user's request and transmit it to the service server. At this time, the requirement data for cell management may include requests for cell management, such as provision, care, manipulation, observation, judgment, collection, re-dispatch, transport, or storage of cells. In addition, the requirement data may include environmental requirements such as temperature/humidity/carbon dioxide, etc. within the cell incubator 50, operation requirements such as intensity of irradiated light, irradiation time, etc., requests for matters requiring management, etc. may include. And the requirement data may include data about a shared space accessible by the administrator, a non-shareable space accessible by the administrator, and a non-shareable space accessible by the robot. In other words, space that can be shared by multiple users and space that cannot be shared are monitored to monitor the access or manipulation of users or robots, and observation information on the state of cells can be collected by administrators who are allowed to view them through the Internet. make it possible

Next, cell management data can be generated using the transmitted requirement data, measurement data, and pre-stored reference data (S310), and the generated cell management data can be transmitted to the cell culture control device and the manager terminal (S320).

In more detail, the service server may search for manager data matching the generated cell management data among a plurality of pre-stored manager data, and transmit the cell management data to the manager terminal corresponding to the searched manager data.

That is, the service server can detect the type of cell management corresponding to the generated cell management data among the plurality of stored manager data, and search for manager data matching the detected type of cell management. Then, the service server may transmit cell management data to the manager terminal corresponding to the retrieved manager data.

For example, when the service server receives requirement data for determining cell status from the user terminal, it compares and analyzes cell image images collected at regular intervals with pre-stored reference image images to determine whether the cell to be measured is normally differentiated. This can be determined by recognizing the video image of the cell to be measured through an image processing program and then comparing it with a reference video image stored in advance according to differentiation or the time elapsed since the start of measurement to determine whether the cell to be measured is normally differentiated. .

If it is determined that the cell to be measured is normally differentiated, the service server stores the operation information of the cell culture device, the video image of the cell to be measured, and the differentiation result, and transmits the result information to the cell culture control device, user terminal, and administrator terminal. It can be controlled as much as possible.

On the other hand, if it is not determined that the cell to be measured is normally differentiated, the service server controls the video image with the abnormality to be transmitted to the cell culture control device, user terminal, and administrator terminal, and takes action on the cell to be measured with the abnormality. Cell management data can be generated for Then, the service server may detect cell collection, which is a type of cell management corresponding to the generated cell management data, among the plurality of stored manager data, and search for manager data that performs the detected cell collection. Then, the service server can transmit cell management data to the terminal of the manager performing cell collection to quickly perform cell collection. At this time, when an abnormality occurs in a cell, the service server can control output of a warning message or warning sound to inform the user terminal and administrator terminal that an abnormality has occurred. For example, the service server can automatically warn if a serious abnormality occurs in the cell, such as temperature, acidity, osmotic pressure, image, etc., and each cell culture control device can automatically adjust matters that require automatic adjustment as pre-entered. It can be.

In addition, the service server can generate action data that can control the environment inside the cell culture device as cell management data and provide it to the cell culture control device, user terminal, and administrator terminal. That is, the service server controls cell culture by generating cell management data including at least one of the strength, frequency, time, and pattern of different magnetic fields in order to control the light irradiation device or the magnetic field irradiation device provided inside the cell culture device. It can be provided to devices, user terminals, and administrator terminals.

In this way, the service server can generate cell management data that can correct abnormalities occurring in the cell culture or cell management process and control the data to be transmitted to the cell culture control device, user terminal, and administrator terminal. Here, the cell management data may include operational data for operating the cell culture device. For example, the service server can generate operating data for controlling the intensity of light irradiated for cell culture, irradiation time, etc., and control it to be transmitted to the cell culture control device, user terminal, and administrator terminal, and may control the operation of the cell culture device. History information can be controlled to be transmitted to the cell culture control device, user terminal, and administrator terminal.

And the final verification items of cell management based on the premise of management history, safety management, and delivery verification include the security of dangerous substance input fraud, that is, the security of maintaining management records and location records, and the security of active maintenance verification of transportation records and visual inspection. . Additionally, there is numerical authentication security for microscopic findings and density meters, and identity verification security for storage, transportation, and comparison of genetic findings. In addition, there is security against contamination by bacteria, security against mixing with animal ingredients, security against mixing with other people and heterogeneous cells, and delivery. These include external safety and security of the container and storage state maintenance security.

In this way, cell management data may include information necessary to manage cells, such as operation, maintenance, repair, disinfection, cleaning, and replacement of consumables, and may require operator manipulation, such as maintenance of the cell incubator or replacement of consumables. In the case of management, the cell management data can be transmitted to the administrator terminal and the administrator can control it to be performed directly.

Meanwhile, the service server can receive analysis results by comparing the collected measurement data and reference data from an external analysis server, and generate cell management data based on the received analysis results. At this time, the external analysis server may be a server operated by an expert in cell culture or a server operated by a professional analysis program or artificial intelligence algorithm.

In this way, cell culture can be managed more efficiently by configuring a network between the cell culture control device, user terminal, administrator terminal, and service server to monitor and manage the cell management process in real time.

At this time, when there are a plurality of user terminals, requirement data can be received for each of the plurality of user terminals, and different cell management data can be generated in response to the received requirement data, so that each user terminal has different requirements for cell management. It has the advantage of satisfying various needs of users.

Next, the service server may calculate management cost data using the requirement data and cell management data (S330), and transmit the calculated management cost data to the user terminal and the administrator terminal (S340). At this time, the service server may reflect at least one of cell management time, cell management type, and management difficulty to calculate management cost data.

More specifically, the service server can determine whether to use the regular payment service according to the requirement data, and can calculate management cost data differently depending on the difficulty of using and managing the regular payment service. For example, when using a regular payment service, management cost data is calculated taking into account the number of users using the regular payment service, and when using analysis results received from an external analysis server, it is managed by dividing it into a separate amount. Cost data can be calculated, and if direct manipulation by the manager is required in the management of cell culture, management cost data can be calculated by setting the manager's cost separately.

In this way, the management cost to be paid varies depending on the type and difficulty of cell management entrusted to each functional location, and each user pays for the entrusted cell management, thereby meeting the needs of various cell care and research. , lowers the cost of shared management personnel and devices, and enables the operation of research types and scales with different needs for each user. In addition, the indirect management function through the Internet allows users and managers to share situational awareness and knowledge about cultivation.

At this time, the service server can use blockchain coins to make payment for management cost data.

Those skilled in the art to which the present invention pertains will understand that the present invention can be implemented in other specific forms without changing its technical idea or essential features. Therefore, the embodiments described above should be understood in all respects as illustrative and not restrictive. The scope of the present invention is indicated by the claims described below rather than the detailed description above, and all changes or modified forms derived from the meaning and scope of the claims and their equivalent concepts should be construed as being included in the scope of the present invention. do.

The present invention can be used in cell management service systems and methods.

1: Cell management service system 50: Cell incubator
100: Cell culture control device 200: User terminal
300: Administrator terminal 400: Service server

Claims (14)

A cell culture control device that collects and transmits measurement data regarding cell culture;
A user terminal that generates and transmits requirement data for cell management, and
A service server that generates cell management data using the requirement data transmitted from the user terminal, the measurement data, and pre-stored reference data, and transmits the generated cell management data to the cell culture control device and the manager terminal.
Cell management service system including. According to claim 1,
The service server is,
Stores multiple manager data according to the type of cell management,
Search for manager data matching the generated cell management data among the plurality of stored manager data,
A cell management service system that transmits the cell management data to an administrator terminal corresponding to the retrieved administrator data. According to claim 2,
The types of cell management are:
A cell management service system that includes at least one of providing cells, maintaining, repairing, disinfecting, cleaning, replacing consumables, managing the cell culture environment, determining cell status, collecting cells, transporting and storing cells. According to claim 1,
The service server is,
A cell management service system that calculates management cost data using the requirement data and the cell management data, and transmits the calculated management cost data to the user terminal and the manager terminal. According to claim 4,
The service server is,
A cell management service system that reflects at least one of cell management time, type of cell management, and management difficulty to calculate the management cost data. According to claim 4,
The service server is,
A cell management service system that allows payment for the management cost data using blockchain coins. According to claim 1,
The above requirement data is,
A cell management service system that includes data on shared spaces accessible by administrators and non-shareable spaces accessible by robots. In the cell management service method performed by a service server supporting cell management service through communication with a cell culture control device, user terminal, and administrator terminal,
Receiving measurement data on cell culture and requirement data for cell management from the cell culture control device and the user terminal, respectively;
Generating cell management data using the transmitted requirement data, the measurement data, and pre-stored reference data, and
Transmitting the generated cell management data to the cell culture control device and the manager terminal
A cell management service method comprising: According to claim 8,
Further comprising the step of storing a plurality of manager data according to the type of cell management,
The step of transmitting the generated cell management data to the cell culture control device and the manager terminal,
Search for manager data matching the generated cell management data among the plurality of stored manager data,
A cell management service method for transmitting the cell management data to an administrator terminal corresponding to the retrieved administrator data. According to clause 9,
The types of cell management are:
A cell management service method including at least one of providing cells, maintaining, repairing, disinfecting, cleaning, replacing consumables, managing the cell culture environment, determining cell status, collecting, transporting, and storing cells. According to claim 8,
Calculating management cost data using the requirement data and the cell management data, and
Cell management service method further comprising transmitting the calculated management cost data to the user terminal and the manager terminal. According to claim 11,
A cell management service method that reflects at least one of cell management time, type of cell management, and management difficulty to calculate the management cost data. According to claim 11,
A cell management service method further comprising the step of allowing payment for the management cost data using a blockchain coin. According to claim 8,
The above requirement data is,
A cell management service method including data on shared spaces accessible by an administrator and non-shareable spaces accessible by a robot.

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