KR20230107454A - Near-infrared blocking antibacterial eye patch and the method of manufacturing eye patch therof - Google Patents

Abstract

The near-infrared ray blocking eye patch of the present invention includes a pad, a wearing band, and an inner surface of the pad and an outer surface of the pad in contact with the eye of the face, and is worn and used on the human eye, the pad component of the pad It is characterized in that a deposition film is formed by depositing 5% by weight or 6% by weight of zinc oxide nanopowder (Nanoparticle-decorated ZnO) on the inner surface of the pad based on 100% by weight of the total material. further forming a deposition film of α-Al ₂ O ₃ :Eu ₃ + powder on the deposited film; The color of the outer surface of the pad is characterized in that green or khaki.
According to the present invention, it has antibacterial properties to prevent transmission of near-infrared rays and to prevent mold and the like. Also, by depositing α-Al ₂ O ₃ :Eu ₃ + powder, there is an effect of blocking near-infrared rays.

Description

Near-infrared blocking antibacterial eye patch and the method of manufacturing eye patch therof}

The present invention relates to a near infrared (hereinafter referred to as ") blocking eye patch and a method for manufacturing the eye patch. More specifically, the present invention prevents transmission of near-infrared rays by using the characteristics of zinc oxide (ZnO, hereinafter referred to as “ZnO”) to block near-infrared rays and antibacterial properties, and the antibacterial properties of 6% by weight of ZnO nano powder. It is a technology related to a near-infrared ray blocking eye patch and a method for manufacturing an eye patch.

In the Korean dictionary, an eye patch is defined as "a piece of cloth such as gauze that covers the sore eye when an eye disease occurs." A conventional eye patch is a cold compress, a warm compress, or a piece of cloth such as gauze used to cover the eyes of an eye disease patient for the purpose of protection, such as a cold compress or a warm compress in ophthalmology. It is used for cloth and is also used after surgical treatment such as surgery for acid cyst or removal of corneal foreign body.

In general, an eye patch is mainly used to prevent eye disease or to prevent ambient light during rest or sleep. The material of the eye patch is manufactured and sold including cotton and hemp, which are natural materials, and synthetic resin, which is an artificial chemical substance, as well as sponge, latex, and rubber poly. Conventional eye bands are mostly made of natural cotton, synthetic resin, or foam latex material, and once used, sweat or sebum of the facial area is stained on the inner side of the eye band, so bacterial infection may cause eye diseases.

As a background art of the present invention, Republic of Korea Utility Model Registration No. 20-0409597 “Functional Eyepatch” (hereinafter referred to as “Prior Art 1”) has been disclosed. Prior Art 1 is an eye patch used for the eyes containing silver nano, tourmaline material, and fragrance, which have a dense structure to increase antibacterial power, negative ions and far-infrared rays, and increase adhesion and warmth in the body of the eye mask made of natural or artificial materials. It's about manufacturing methods. Since the prior art 1 has antibacterial power in itself, the eye patch itself has antibacterial power even after long-term use, so it is possible to block bacterial infection.

Republic of Korea Utility Model Registration No. 20-0395881 “sleep eye patch” hereinafter referred to as “prior art 2”) has been disclosed. Prior Art 2 relates to a sleep eye patch in which an anion-emitting material is included in the sleep eye patch and a magnet is provided to induce a deep sleep of the sleep eye patch wearer so that the wearer can have a comfortable and comfortable sleep to improve health.

1 is a view of an embodiment of the sleep mask of the prior art 2. In the sleeping mask 1, wearable bands 11 are attached to both sides of the pad 10, the pad 10 and the wearable band 11 are formed of a flexible material, and the length of the wearable band 11 is adjusted. A ring 12 is provided, tourmaline grains generating negative ions are built in the inner space of the pad 10, and a fabric cover 20 is covered on the outside of the pad 10. to be characterized

Republic of Korea Patent Registration No. 10-1964165 “Method for manufacturing non-woven fabric having blood circulation and antibacterial properties” hereinafter referred to as “Prior Art 3”) has been published. In prior art 3, the electrospinning solution prepared in the electrospinning solution composition step contains 2.5% by weight of zinc oxide powder having a nanoparticle size, 5.5% by weight of pegmatite powder pulverized to a particle size of 0.1 μm, and the remainder of PVDF (polyvinylidene difluoride: polyvinylidene difluoride). fluoride) in a solvent.

Here, the zinc oxide (Zinc Oxide) is known to have an effect of helping cell division by being involved in the synthesis of DNA and RNA when ingested and strengthening immune function, and when applied to the skin, it is said to have a sunscreen effect. It is known.

However, it is used to increase antibacterial, deodorizing, and deodorizing properties by being contained in the filament itself constituting the eye patch. In particular, since zinc oxide has a very high melting point, it is not used in a molten state when manufacturing nonwoven fabrics, but nano zinc oxide processed into nano sizes is used, which is commonly used in the market. However, such prior art has a problem in that it does not have effective antibacterial properties.

Korea Utility Model Registration No. 20-0409597 Korean Utility Model Registration No. 20-0395881 Republic of Korea Patent No. 10-1964165

An object of the present invention is to find a specific form among various forms of zinc oxide (ZnO) to block near infrared rays (NIR) and to provide a near infrared ray blocking antibacterial eye patch to prevent near infrared ray transmission and mold.

Another object of the present invention is to provide an eyepatch in which α-Al ₂ O ₃ :Eu ₃ + powder is deposited on which zinc oxide nanofire is deposited in order to more effectively block near-infrared rays.

Another object of the present invention is to provide a method for manufacturing a near-infrared ray blocking eye patch in which seaweed nano-carbonized powder is added as a far-infrared emitting material.

The near-infrared ray blocking eye patch of the present invention includes a pad, a wearing band, and an inner surface of the pad and an outer surface of the pad in contact with the eye of the face, and is worn and used on the human eye, the pad component of the pad It is characterized in that a deposition film is formed by depositing 5% by weight or 6% by weight of zinc oxide nanopowder (Nanoparticle-decorated ZnO) on the inner surface of the pad based on 100% by weight of the total material.

In addition, the near-infrared ray blocking eye patch of the present invention further forms a deposition film of α-Al ₂ O ₃ :Eu ₃ + powder on the deposition film; The color of the outer surface of the pad is green or khaki; It is characterized in that it further comprises seaweed nano-carbonized powder as an additive.

The method for manufacturing a near-infrared ray blocking eye patch of the present invention comprises the steps of depositing zinc oxide on a carbon fiber substrate using an RF magnetron deposition process; Growing zinc oxide nanopowder on carbon fibers using hydrothermal synthesis; Standard cleaning in the order of acetone, methanol, and distilled water for 5 minutes each to remove organic matter and impurities present in the carbon fiber with an ultrasonic plate washer; drying with nitro nitrogen gas (N2 gas); It is characterized in that it comprises the step of depositing a silver nanowire electrode by a spray coating method.

In addition, the near-infrared ray blocking eye patch of the present invention is manufactured by the manufacturing method of the near-infrared ray blocking eye patch.

The near-infrared (NIR) blocking eye patch of the present invention effectively prevents transmission of near-infrared rays and has antibacterial properties to prevent mold and the like. Also, by depositing α-Al ₂ O ₃ :Eu ₃ + powder, there is an effect of blocking near-infrared rays.

In addition, the near-infrared ray blocking eye patch of the present invention can effectively block near-infrared rays by using a green or khaki color. In addition, the near-infrared ray blocking eye patch of the present invention has the effect of emitting far-infrared rays by adding seaweed nano-carbonized powder, which is a natural material.

1 is a perspective view of a sleep mask in the prior art.
Figure 2 (a) shows the results when not using the eye patch, and FIG. 2 (b) shows the result when using the near infrared ray blocking eye patch.
3(a) shows surface reflection, FIG. 3(b) shows internal reflection, and FIG. 3(c) shows transmission NIR.
4 shows near-infrared reflectance according to color.
5 is a near infrared (NIR) reflectance spectrum of synthesized ZnO.
6(a) is a SEM image of carbon fiber before depositing a ZnO seed layer.
6(b) is a SEM picture of carbon fiber after depositing a ZnO seed layer.
7 is E. coli (plate (A) and
It shows antibacterial activity against Staphylococcus aureus (plate (B)).
8(a) is a TEM photograph, and FIG. 8(b) is a Eu3+ doped α-Al ₂ O ₃ nanophosphor distribution.
9 is a diffuse reflectance (DR) and absorption of the synthesized Al ₂ O ₃ :Eu ₃₊ (1 mol.%) nanophosphor.
represents the spectrum
10 shows a manufacturing process of the near-infrared ray blocking eye patch of the present invention.

In the following description, only parts necessary for understanding the contents of the present invention are described, and descriptions of other well-known technologies are omitted so as not to obscure the subject matter of the present invention.

Figure 2 (a) shows the results when not using the eye patch, and FIG. 2 (b) shows the result when using the near infrared ray blocking eye patch. 3(a) shows surface reflection, FIG. 3(b) shows internal reflection, FIG. 3(c) shows transmission NIR, and FIG. 4 shows near-infrared reflectance according to color. 5 is a NIR reflectance spectrum of synthesized ZnO, FIG. 6(a) is a SEM picture of carbon fibers before depositing a ZnO seed layer, and FIG. 6(b) is a SEM picture of carbon fibers after depositing a ZnO seed layer. Figure 7 shows the antibacterial activity of PCL membranes prepared with different concentrations of ZnO nanoparticles against Escherichia coli (plate (A) and Staphylococcus aureus (plate (B)), and Figure 8 (a) is a TEM photograph, Figure 8 (b) shows the distribution of Eu3+ doped α-Al ₂ O ₃ nanophosphor Figure 9 shows the diffuse reflectance (DR) and absorption spectrum of the synthesized Al ₂ O ₃ :Eu ₃₊ (1 mol.%) nanophosphor 10 shows a manufacturing process of the near-infrared ray blocking eye patch of the present invention.

The light reaching the ground from sunlight consists of 10% ultraviolet rays, 40% visible rays, and 50% infrared rays, and harmful rays exposed in daily life can be largely divided into ultraviolet rays, blue rays, and near-infrared rays.

<ultraviolet rays>

Ultraviolet rays have a wavelength range of 10nm-400nm, and have a shorter wavelength than visible light that can be seen by the human eye, and the cornea and lens of the eye absorb ultraviolet rays.

Ultraviolet light can generally be divided into UV-A, UV-B and UV-C.

Most of UV-C is absorbed in the ozone layer and has no significant effect on the human body, but UV-A and UV-B penetrate through the atmosphere and, when excessively exposed, damage the DNA of the skin cells and cause genetic mutations that cause skin cancer.

When the eye is exposed to ultraviolet rays like the skin, the cells on the surface of the cornea and conjunctiva are damaged and exfoliated, and inflammation occurs as the skin is burned, as if the skin is burned. And it causes symptoms such as eye pain, tearing, and glare. As the cornea, which blocks ultraviolet rays, becomes thinner at the time when refractive surgery, such as LASIK and LASEK, becomes more active, it is necessary to pay more attention to UV protection. Light passing through the eye as well as outside passes through the pupil, lens and vitreous to reach the retina.

In this case, it can cause cataracts in the lens and macular degeneration in the retina. If you look closely at each wavelength range, UV-A has a wavelength range of 320-400 nm, which is the longest among ultraviolet wavelengths. It accounts for up to 95% of the UV rays that reach the Earth and passes through the ozone layer to reach Earth. UV-A shows relatively the same intensity throughout the year regardless of the weather and has a strong penetrating power, penetrating some clothing, clouds and even glass. Compared to other rays, it can cause skin aging and wrinkles.

UV-B has a wavelength range of 290-320 nm, and the intensity is not always the same because the amount of light varies depending on the season. Excessive exposure to UV-B damages the epidermal layer of the skin, causing red flushing, and UV-B is more often cited as the cause of skin cancer than UV-A rays.

It blocks 99% of UV rays up to 400 nm, and as the number of patients undergoing eye-related surgeries such as LASIK, LASEK, and cataract increases, interest in UV protection after surgery is increasing. Therefore, UV-blocking lenses are widely used as prescription glasses and eye protection glasses. As the sunlight gets stronger in the summer, many people wear sunglasses to block UV rays and prevent glare. Sunglass lenses are also released with UV blocking function added, and as the media mentions the UV blocking rate and lifespan of sunglasses lenses, there are many cases in which the sunglasses frame is used as it is and only the spectacle lens is replaced with one that blocks UV rays.

<blue light>

Blue light is a region tinged with blue light in the visible light region. The wavelength range is 400-500nm, and it is generated from sunlight as well as digital devices such as smartphones, monitors, and TVs.

Blue light has a very close relationship in the lives of modern people who use a lot of smart devices. Exposure to blue light for a long time increases eye fatigue, causes dry eyes, and in severe cases may cause damage to the lens or retina. In addition, when using digital devices such as smartphones, monitors, and TVs in a dark environment late at night, the secretion of melatonin, a sleep-inducing hormone, is reduced, which can cause sleep disorders.

There are retinal ganglion cells in the retina, which play a very important role in the body's rhythm of day and night. However, these cells respond to blue light, and if they are continuously exposed even at night, these cells can be activated and adversely affect the body rhythm.

In a study using rat eyes to find out how exposure to blue light affects visual cells, blue light increases the amount of active oxygen in the eye, accelerates the aging of visual cells, and has a detrimental effect on the retina.

A case has also been reported in which a student was exposed to blue light for a long time and became colorblind. If you use your smartphone a lot even late at night, your pupils will dilate in a dark environment, which increases your exposure to blue light, which can pose a risk to your eye health. At Harvard Medical School in the United States, exposure to blue light at night can be dangerous, so caution is required. As above, many studies on the harmful effects of blue light have been conducted.

The spectacle lens industry also recognizes the harmfulness of blue light and adds a function to block some blue light to the spectacle lens, which is commercialized as a spectacle lens that blocks harmful rays.

Manufacturing methods of blue light blocking lenses are largely divided into dye coloring and coating methods. In the case of dye coloring, there is an advantage in that the blue light blocking rate can be increased through special dyes, but there is a disadvantage in that the luminous transmittance is lowered and the visibility is lowered when the color is entered.

Therefore, it does not matter to wearers who use tinted lenses such as sunglasses, but dye coloring is not suitable for wearers who use achromatic lenses or have color-sensitive industries. In the case of the coating method, the advantage is that there is no sense of difference in seeing the color of the object because it is transparent. However, the higher the reflectance, the more stray light is generated and the image quality deteriorates, so the blue light blocking rate is lower than that of dye coloring.

<near infrared rays>

Near infrared rays (NIR) belong to the wavelength range of 780-1400 nm and are located outside of red, so they are called infrared rays. Infrared rays have a higher luminous body temperature than visible rays or ultraviolet rays, so they are also called “thermal rays”. It is commonly used for medical and industrial purposes.

The near-infrared ray is a region of 780-1400 nm with a short wavelength among infrared rays. Its penetration is very high, so for medical purposes, it penetrates deeply into the local affected area to activate mitochondria and expand blood vessels by increasing body temperature to help regeneration by promoting metabolism and removing wastes.

In particular, in the case of infrared medical devices widely used in ophthalmology, they are widely used to relieve dry eye syndrome and inflammation. It has been reported that dry eye symptoms were improved by stimulating meibomian glands through thermal therapy using near-infrared rays twice a day for 2 weeks in patients complaining of dry eye.

However, continuous and excessive exposure to near-infrared rays can lead to adverse effects. Near-infrared rays have high penetrating power, so when exposed to the skin, they penetrate up to about 6 mm, increase the internal temperature of the skin, and cause degeneration in the dermal layer, accelerating skin aging such as loss of elasticity and dryness.

Some studies have suggested that it is necessary to prevent photoaging and carcinogenesis by blocking not only ultraviolet rays but also near-infrared rays. When our eyes are exposed to near-infrared rays for a long time, the temperature inside the eyeball increases, which can adversely affect the cornea, lens, and inner retina. This can cause various eye diseases such as dry eyes, cataracts, and macular degeneration.

Recognizing the above harmfulness, the spectacle lens industry has recently launched a near-infrared ray blocking lens to protect the eyes.

The eye patch of the embodiment of the present invention has a structure similar to that of FIG. 1 sleeping eye patch.

In the structure of the near-infrared ray blocking eye patch in Example 1 of the present invention, a wearable band is attached to both sides of the pad, a ring for adjusting the length is provided on the wearable band, and a near-infrared ray blocking material such as zinc oxide nanopowder is provided on the inner surface of the pad. and additives are deposited.

Figure 2 (a) shows when not using the eye patch, Figure 2 (b) shows the use of the near-infrared ray blocking eye patch.

When the eye patch is not used, near-infrared rays are transmitted as it is, which can cause various eye diseases such as dry eye, cataract, and macular degeneration.

3 is a NIR measurement mode. FIG. 3(a) shows surface reflection, FIG. 3(b) shows internal reflection, and FIG. 3(c) shows transmitted NIR.

4 shows near-infrared reflectance according to color.

Green and khaki are the colors with the highest reflectance in the near-infrared region. Therefore, it is preferable to use a green or khaki color for the eye patch fiber according to an embodiment of the present invention to prevent transmission of near-infrared rays.

5 shows the NIR reflection spectrum of the synthesized ZnO.

Zinc oxide (ZnO) is a white powder pigment commonly used as a pigment. Because of the dependence of ZnO's electronic and optical properties on size and dimensionality (granular, planar, rod shape), the fabrication of structures with controlled crystal morphology is required. The optical properties of ZnO powder are greatly influenced by the particle size and shape.

The scattering efficiency of ZnO pigments can be greatly improved by using nanostructured pigments.

Samples coated with ZnO nanopowder showed improved reflectivity compared to other materials.

In the near-infrared region (780-1400 nm), it can be seen that ZnO-coated nanoparticles have the highest reflectance compared to other materials. The results showed that the optical properties of the ZnO nanopowder were strongly influenced by the particle size and shape.

Zinc oxide nanopowder (Nanoparticle-decorated ZnO) showed the highest NIR reflectance. Next, Scale-like ZnO and Submicrorods ZnO (submicrorod ZnO) showed similar near-infrared reflectance, followed by Nanorods ZnO (nanorod ZnO) and Microrods ZnO (microrod ZnO). ) showed similar near-infrared reflectance.

As a result of the above experiment, it can be seen that ZnO nanoparticle-decorated exhibits the strongest near-infrared reflectance, so that ZnO nanoparticle-decorated can greatly improve the near-infrared scattering efficiency of optimized ZnO pigments.

The ZnO nanopowder has the following properties in order to have antibacterial properties on the eye patch according to Example 1 of the present invention. Zinc (Zn) is an essential trace element that plays an important role in cell biological functions such as calcification, hormone activity, and DNA synthesis. Zinc oxide (ZnO) is a widely used inorganic substance and is classified as a GRAS substance (generally recognized as safe: a chemical substance recognized as a generally safe substance recognized by the FDA) by the US Food and Drug Administration (FDA).

Recently, ZnO nanopowder has been applied to research for various uses such as dental restorative materials, wound dressing materials, and tissue engineering due to its various functions, especially antibacterial activity.

ZnO nanopowder causes oxidative stress by generating reactive oxygen species (ROS), especially H ₂ O ₂ , and has antibacterial activity against a wide range of gram-positive and gram-negative bacteria through a mechanism in which nanoparticles accumulate in the cytoplasm and membrane of bacteria. is known to have According to previous studies, ZnO has been reported to have a positive effect on the activity of fibroblasts and osteoblasts as well as antibacterial properties.

<Example 1> Preparation of ZnO nanopowder

Pure ZnO nanopowder (Nanoparticle-decorated ZnO) is synthesized using an autocombustion method. An appropriate amount of zinc nitrate (Zn(NO3)2*?* and glycine is mixed in 100 mL of distilled water. The whole system is transferred to a hot plate at 300° under constant agitation (fixed at 550 rpm). Then 1 hour After 30 minutes, the solution turns into a gel.

After a few minutes, combustion starts, during combustion, a lot of volatile gases such as CO ₂ and N2 are generated, and an off-white powder of ZnO is obtained. The dry powder is further ground to obtain a fine powder.

The manufacturing process of the ZnO near-infrared eye patch according to Example 1 of the present invention is (1) depositing zinc oxide using a carbon fiber substrate using an RF magnetron sputtering process, and then (2) oxidizing it using a hydrothermal synthesis method Zinc nanopowder (Nanoparticle-decorated ZnO) is grown on carbon fiber. (3) In order to remove unnecessary organic substances and impurities present in the carbon fiber substrate, standard cleaning is performed using an ultrasonic cleaner in the order of acetone, methanol, and deionized water (DI water) for 5 minutes each, and dried with N2 gas. (4) Then, silver nanowire electrodes are deposited by the spray coating method.

Specifically, RF magnetron sputtering requires a zinc oxide seed layer to grow a zinc oxide powder structure. The RF magnetron sputtering process is used to construct the zinc oxide seed layer on the carbon fiber. The degree of vacuum in the chamber before deposition is maintained at 2 torr, and 10 sccm of Ar gas is injected at room temperature.

The RF plasma power is 150W and the deposition working pressure is 15mtorr. The pre-sputtering process time is 10 minutes, and the sputtering process is performed for 20 minutes to sufficiently create an Ar atmosphere in the chamber, and the substrate is rotated 50 times per minute for uniformity of the thin film. After the deposition, the seed layer of zinc oxide has a thickness of about 100 nm when analyzed by SEM (Scanning Electron Microscopy: a microscope that observes the surface of a sample placed in a vacuum with a 1 to 100 nm electron beam).

10 shows a manufacturing process of the near-infrared ray blocking eye patch of the present invention.

The manufacturing process of the near-infrared transmission-blocking eye patch of the present invention includes the steps of preparing zinc oxide nanopowder; Depositing zinc oxide on a carbon fiber substrate using an RF magnetron deposition process; Growing zinc oxide nanopowder on carbon fibers using hydrothermal synthesis; Standard cleaning in the order of acetone, methanol, and distilled water for 5 minutes each to remove organic matter and impurities present in the carbon fiber with an ultrasonic plate washer; drying with nitro nitrogen gas (N2 gas); It is configured to include the step of depositing a silver nanowire electrode by a spray coating method.

FIG. 6 is an SEM picture, FIG. 6(a) is an SEM picture of carbon fiber before depositing a ZnO seed layer, and FIG. 6(b) is a SEM picture of carbon fiber after depositing a ZnO seed layer.

The following [Table 1] summarizes the RF sputtering process conditions used for the deposition of the zinc oxide seed layer.

Target ZnO Substrate Carbon fibers Base pressure 1.5 ^-6 Torr Deposition pressure 3.5 mTorr Plasma power 150w Gas Ar Deposition temperature RT

7 shows the antibacterial activity of polycaprolactone (PCL) membranes prepared by varying the concentration of ZnO nanopowder against Escherichia coli (plate (A)) and Staphylococcus aureus (plate (B)).

PCL solutions with various concentrations of ZnO nanoparticles were prepared in acetone. That is, the ZnO nanoparticles were properly dispersed in acetone by sonication for 15 min at various concentrations. Both plates show only (a) 2wt%, (b) 3wt%, (c) 4wt%, (d) 5wt% and (e) 6wt% ZnO nanopowders and (f) PCL membrane.

The added zinc oxide is a nanopowder with a diameter of less than 50 nm.

As a solvent, dichlorometane (99.9%), Extra Dry, Stabilized, Acros organics, USA) is used. The antibacterial activity of polycaprolactone fiber mats filled with ZnO nanopowder was observed against gram-negative (Escherichia coli) and gram-positive (Staph-ylococcus aureus) bacteria (based on the disk diffusion method). The activity of a pure polycaprolactone (PCL) membrane against these bacteria was used as a control.

It was demonstrated that the membrane prepared according to Example 1 of the present invention had excellent antibacterial activity against both Escherichia coli and Staphylococcus aureus.

According to the results obtained, pure PCL membrane and ZnO nanopowder content of less than 5% by weight show no activity against bacteria. The PCL membrane containing 5% ZnO nanopowder showed statistically significant antibacterial activity against Escherichia coli and Staphylococcus aureus with inhibition zone diameters of 8.76*?* and 9.98*?*, respectively.

PCL membranes containing 6% ZnO nanopowders exhibited inhibition zone diameters of 9.81*?* and 10.22*?* for E. coli and Staphylococcus aureus, respectively.

Antibacterial activity was evident only at 5 and 6% by weight of ZnO nano powders.

This is because at low concentrations, the nanoparticles are trapped inside the polymer matrix, and very few nanoparticles come into direct contact with the bacterial cells. The antibacterial activity of ZnO nanoparticles occurs only when the nanoparticles are in direct contact with the bacterial cell wall.

In the eye patch applied in Example 1 of the present invention, the eye patch component contains 5% by weight or 6% by weight of zinc oxide nanopowder (Nanoparticle-decorated ZnO) based on 100% by weight of the total material of the eye patch. It is deposited on the surface of the inner side, and the color of the outer side of the eye patch is characterized in that green or khaki.

The following [Table 2] shows the inhibition zone diameter of the disk diffusion method.

sample Inhibition zone diameter (mm) Escherichia coli Staphylococcus aureus Neat PCL membrane 6.00*?* 6.00*?* PCL/2%ZnO 6.00*?* 6.00*?* PCL/3%ZnO 6.00*?* 6.00*?* PCL/4%ZnO 6.00*?* 6.00*?* PCL/5%ZnO 8.76*?* 9.98±0.6 PCL/6%ZnO 9.81*?* 10.22 *?*

<Example 2>

As another embodiment of the present invention, Example 2 is a method of depositing α-Al ₂ O ₃ :Eu ₃ + powder on green or khaki fibers of an eye patch. The manufacturing method of α-Al ₂ O ₃ powder doped with Eu ₃₊ is as follows.

High-purity aluminum nitrate nanohydrate [Al(NO ₃ ) ₃ ?9H ₂ O], europium (III) nitrate hexahydrate [Eu(NO ₃ ) ₃ ?6H ₂ O], and urea (H ₂ NCONH ₂ ) are combined in a solution combustion method. is used as a starting material for the synthesis of α-Al ₂ O ₃ :Eu ₃ + nanophosphor (1 mol.%). The drug used is included according to the chemical reaction by the following formula (1) in a molar ratio of 2:5.

Equation (1): (2-x)Al(NO ₃ ) ₃ *** ₂ O+xEu(NO ₃ ) ₃ *** ₂ O+5CO(NH ₂ ) ₂

→ Al ₂ -xEuxO ₃ +biproducts

In the case of complete combustion, the oxidant to fuel ratio remains unity because the maximum heat is produced at this ratio. These nitrates and urea are first mixed with a minimum amount of deionized water in an agate mortar to obtain a clear viscous gel.

Transfer the gel into a preheated muffle furnace maintained at 550°.

The gel quickly dehydrates with the evolution of large amounts of gas and burns with a white flame, producing a bulky white product. The entire combustion process is completed within 3 minutes. Thereafter, the resultant product is taken out of the muffle furnace and pulverized into fine powder to prepare a synthetic nanophosphor.

The shape and size of the synthesized nanophosphors were analyzed by electron microscopy using a Transmission Electron Microscopy (TEM). It was measured using a spectrophotometer in the 190-1400 nm region using a spectrometer spectrum.

FIG. 8 (a) TEM image, (b) shows the particle size distribution of Eu ₃₊ doped Al ₂ O ₃ nanophosphors. The morphology and crystallinity of the nanophosphors were analyzed by TEM measurement.

8(a) shows a TEM image of the α-Al ₂ O ₃ :Eu ₃₊ nanophosphor having a spherical shape. The size distribution of the nanopowder is shown in FIG. 8(b). A change in particle distribution is observed from 7 to 33 nm with an average particle size of 18 nm as determined by statistical analysis.

9 shows the diffuse reflectance (DR) and absorption spectrum of the synthesized Al ₂ O ₃ :Eu ₃₊ (1 mol.%) nanophosphor. As shown in the graph, it can be seen that the near-infrared ray (780 to 1400 nm) shielding property of the α-Al ₂ O ₃ powder doped with Eu ₃₊ is almost 100% shielding.

<Example 3>

In Example 3 of the present invention, the zinc oxide nanopowder (Nanoparticle-decorated ZnO) prepared in Example 1 is deposited on the inner surface of green or khaki fiber, and the α-Al ₂ O ₃ prepared in Example 2 is deposited thereon. :Eu ₃ + powder is deposited to produce an eye patch.

As shown in FIG. 4, green or khaki has the highest near-infrared shielding characteristics, and as shown in FIG. 9, α-Al ₂ O ₃ powder doped with Eu ₃₊ has a near-infrared shielding characteristic. am.

A small amount of seaweed nano-carbonized powder or tourmaline powder, which is a far-infrared ray emitting material, may be added as an additive to each of the above examples. In addition, additives are deposited by adding as additives together with nanoparticle-decorated ZnO or α-Al ₂ O ₃ :Eu ₃ + powder.

The color of the outer surface of the eye patch used in Example 3 of the present invention is green or khaki.

In addition, in the present invention, seaweed nano-carbonized powder and tourmaline powder may be added as far-infrared ray emitters. In addition, in detail, Example 3 of the present invention has various forms of ZnO, that is, nanoparticle-decorated ZnO, scale-like ZnO, submicrorods Zn (ZnO), and nanorods. There are ZnO (Nanorods ZnO) and microrods ZnO (microrods ZnO). In Example 3 of the present invention, an eyepatch is manufactured using zinc oxide nanopowder (Nanoparticle-decorated ZnO) having the highest reflectance.

On dl, the present invention is described through Examples 1 to 3 of the present invention and described in the claims. Matters described in the claims should be construed as belonging to the scope of the present invention as equivalents that have been changed within the scope of technical matters.

The components of the near-infrared ray blocking eye patch of the present invention block near-infrared rays by depositing 5% or 6% by weight of zinc oxide nanopowder (Nanoparticle-decorated ZnO) on the inner surface of the pad in contact with the eye, based on 100% by weight of the total pad material, As an eye patch that emits natural far-infrared rays with antibacterial properties, it is an industrially useful invention because its effect is superior.

Claims (6)

In the eye patch, which includes a pad, a wearing band, and an inner surface of the pad and an outer surface of the pad in contact with the eyes of the face, and is worn and used on the human eye,
The pad component is near-infrared blocking, characterized in that a deposition film is formed by depositing 5% by weight or 6% by weight of zinc oxide nanopowder (Nanoparticle-decorated ZnO) on the inner surface of the pad based on 100% by weight of the total material of the pad. eye patch.
The near-infrared ray blocking eye patch according to claim 1, wherein a deposition film of α-Al ₂ O ₃ :Eu ₃ + powder is further formed on the deposition film.
The near-infrared ray blocking eye patch according to claim 1, wherein the color of the outer surface of the pad is green or khaki.
. The near-infrared ray blocking eye patch according to claim 1, further comprising seaweed nano-carbonized powder as an additive.
In the near-infrared ray blocking eye patch manufacturing method,
Depositing zinc oxide on a carbon fiber substrate using an RF magnetron deposition process; Growing zinc oxide nanopowder on carbon fibers using hydrothermal synthesis; Standard cleaning in the order of acetone, methanol, and distilled water for 5 minutes each to remove organic matter and impurities present in the carbon fiber with an ultrasonic plate washer; drying with nitro nitrogen gas (N2 gas); A method for manufacturing a near-infrared ray blocking eye patch, comprising the step of depositing a silver nanowire electrode by a spray coating method.
A near-infrared ray blocking eye patch manufactured by the method of manufacturing a near-infrared ray blocking eye patch of claim 5.

Images