KR20230066023A - p53의 R273C 또는 Y220C 돌연변이를 인식하는 T 세포 수용체 - Google Patents

p53의 R273C 또는 Y220C 돌연변이를 인식하는 T 세포 수용체 Download PDF

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KR20230066023A
KR20230066023A KR1020237011380A KR20237011380A KR20230066023A KR 20230066023 A KR20230066023 A KR 20230066023A KR 1020237011380 A KR1020237011380 A KR 1020237011380A KR 20237011380 A KR20237011380 A KR 20237011380A KR 20230066023 A KR20230066023 A KR 20230066023A
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amino acid
acid sequence
seq
polypeptide chain
chain comprises
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상현 김
니콜라오스 자카라키스
스티븐 에이 로젠버그
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더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈
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Application filed by 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 filed Critical 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈
Publication of KR20230066023A publication Critical patent/KR20230066023A/ko
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KR1020237011380A 2020-09-04 2021-09-02 p53의 R273C 또는 Y220C 돌연변이를 인식하는 T 세포 수용체 Pending KR20230066023A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063074747P 2020-09-04 2020-09-04
US63/074,747 2020-09-04
PCT/US2021/048786 WO2022051449A2 (en) 2020-09-04 2021-09-02 T cell receptors recognizing r273c or y220c mutations in p53

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KR20230066023A true KR20230066023A (ko) 2023-05-12

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KR1020237011380A Pending KR20230066023A (ko) 2020-09-04 2021-09-02 p53의 R273C 또는 Y220C 돌연변이를 인식하는 T 세포 수용체

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US (1) US20230321240A1 (https=)
EP (1) EP4208473A2 (https=)
JP (1) JP2023540123A (https=)
KR (1) KR20230066023A (https=)
CN (1) CN116472050A (https=)
AU (1) AU2021336399A1 (https=)
CA (1) CA3191186A1 (https=)
GB (1) GB2614166A (https=)
TW (1) TWI900647B (https=)
WO (1) WO2022051449A2 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024206274A2 (en) 2023-03-27 2024-10-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services T cell receptors targeting y220c or r175h mutation in p53

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003265948B8 (en) 2002-09-06 2009-09-03 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Immunotherapy with in vitro-selected antigen-specific lymphocytes after nonmyeloablative lymphodepleting chemotherapy
US8383099B2 (en) 2009-08-28 2013-02-26 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Adoptive cell therapy with young T cells
WO2012129201A1 (en) 2011-03-22 2012-09-27 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of growing tumor infiltrating lymphocytes in gas-permeable containers
IL290655B2 (en) 2014-05-29 2024-05-01 Us Health Anti-human papillomavirus 16 E7 T-cell chelates
WO2018102585A1 (en) * 2016-11-30 2018-06-07 Advaxis, Inc. Personalized immunotherapy in combination with immunotherapy targeting recurrent cancer mutations
AU2018318303A1 (en) * 2017-08-18 2020-04-09 Gritstone Bio, Inc. Antigen-binding proteins targeting shared antigens
CA3080274A1 (en) * 2017-09-29 2019-04-04 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods of isolating t cells having antigenic specificity for a p53 cancer-specific mutation
EA202090757A1 (ru) * 2017-09-29 2020-08-21 Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез T-КЛЕТОЧНЫЕ РЕЦЕПТОРЫ, РАСПОЗНАЮЩИЕ МУТАНТНЫЙ p53

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GB2614166A (en) 2023-06-28
JP2023540123A (ja) 2023-09-21
CA3191186A1 (en) 2022-03-10
TWI900647B (zh) 2025-10-11
EP4208473A2 (en) 2023-07-12
CN116472050A (zh) 2023-07-21
WO2022051449A3 (en) 2022-04-14
WO2022051449A2 (en) 2022-03-10
AU2021336399A1 (en) 2023-05-18
US20230321240A1 (en) 2023-10-12
TW202227477A (zh) 2022-07-16
AU2021336399A9 (en) 2023-07-13

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