KR20230028605A - Liquid composition comprising saccharides system surfactant - Google Patents

Abstract

The present invention relates to a liquid composition using a saccharide-based surfactant and, more specifically, to a liquid composition, wherein alkyl polyglucoside, which is a nonionic surfactant among saccharide-based surfactants, and alkylglucose carboxylate salt, which is an anionic surfactant, are used together to show excellent detergency, foaming power and rinsing performance, and low skin irritation and cytotoxicity.

Description

Liquid composition containing sugar-based surfactant {LIQUID COMPOSITION COMPRISING SACCHARIDES SYSTEM SURFACTANT}

The present invention relates to a liquid composition using a saccharide-based surfactant, and more particularly, among saccharide-based surfactants, an alkyl polyglucoside, which is a nonionic surfactant, and an alkyl glucose carboxylate salt, which is an anionic surfactant, are used together. It is directed to a liquid composition with excellent detergency, foaming power, and rinsing performance, and low skin irritation and cytotoxicity.

Surfactants are compounds that have both hydrophilic and lipophilic groups in one molecule, and there are more than tens of thousands of types that exist in natural ecosystems or are made synthetically.

Surfactants have functions such as emulsification, solubilization, dispersion, cleaning, wetting, foaming, antistatic, and sterilization, and are used in detergents, textiles, cosmetics, medicines, foods, paints, pesticides, paper, mining, lubricants, civil engineering, construction, It is used in various industries such as rubber, plastic, oil extraction, and soil regeneration.

In particular, household and industrial detergents used for the purpose of hygiene and cleanliness contain surfactants as a main component and play a key role in cleaning.

However, sodium lauryl sulfate (SLS) anionic surfactants, which are commonly used the most throughout the industry, have excellent cleaning ability, but cause skin irritation. Specifically, it damages skin proteins and hair follicles, causes itching and dryness, and shampoos have problems with irritation of the scalp and eyes.

Sodium Laureth Sulfate (SLES) anionic surfactant was designed to reduce the irritation of the sodium lauryl sulfate (SLS) anionic surfactant. Specifically, in order to reduce the irritation of sodium lauryl sulfate (SLS), it undergoes an ethoxylation reaction, and through this reaction, ethylene oxide is added to lighten and soften the ingredients, thereby solving the problem of the anionic surfactant itself. wanted to solve it.

However, irritants such as 1,4-dioxane are generated by ethylene oxide added during the synthesis of sodium laureth sulfate (SLES) anionic surfactant, which causes skin irritation and cytotoxicity. There is a problem that causes it.

Therefore, the development of surfactants with higher stability and excellent biodegradability is required.

As a specific alternative, alkyl polyglucoside nonionic surfactants synthesized from fatty acids extracted from plants such as palm and coconut and sugar-based glucose have been proposed.

Alkyl polyglucoside nonionic surfactants, which are naturally derived substances, are widely used in various industrial fields due to their good decontamination and low biodegradability and low skin irritation when used in detergents.

However, alkyl polyglucoside nonionic surfactants have a problem in that they have relatively low detergency and foaming power compared to conventional anionic surfactants such as sodium lauryl sulfate (SLS) and sodium laureth sulfate (SLES).

Therefore, there is a need to develop a liquid composition that exhibits excellent detergency and foaming power, yet exhibits excellent cell viability with less skin irritation compared to sodium lauryl sulfate (SLS) and sodium laureth sulfate (SLES) anionic surfactants.

Korean Patent Publication No. 10-2021-0063532 Korean Patent Registration No. 10-1125893

Accordingly, the present inventors of the present invention use alkyl polyglucoside nonionic surfactants, which are naturally derived substances that can replace existing anionic surfactants such as sodium lauryl sulfate (SLS) and sodium laureth sulfate (SLES), When applied to detergents, it was confirmed that the biodegradability was excellent, but the detergency and foaming power tended to be lower than those of conventional surfactants. In order to solve this problem, it was confirmed that when the alkyl polyglucoside anionic surfactant and the alkylglucose carboxylate salt anionic surfactant are used together, the cleaning power, foaming power, and rinsing property are increased compared to the use of the alkyl polyglucoside anionic surfactant alone. Thus, the present invention was completed.

In order to solve the above problems, the present invention discloses the following means.

Specifically, the present invention provides a liquid composition comprising (a) an alkylpolyglucoside nonionic surfactant represented by Formula 1; and (b) an alkylglucose carboxylate salt anionic surfactant represented by Formula 2.

The liquid composition of the present invention has excellent detergency and foaming power, and has the advantage of exhibiting excellent cell viability with less skin irritation compared to sodium lauryl sulfate (SLS) and sodium laureth sulfate (SLES) anionic surfactants.

The present invention discloses a product comprising the liquid composition.

In the liquid composition of the present invention, by using an alkyl polyglucoside nonionic surfactant and an alkylglucoose carboxylate salt anionic surfactant together, the cleaning power, foaming power, and rinsing property can be increased compared to the case of using the alkyl polyglucoside alone.

In addition, it may be safer in terms of skin irritation and cytotoxicity compared to sodium laureth sulfate (SLES) anionic surfactants.

Therefore, if the characteristics of the liquid composition are used, it can be usefully applied to household chemicals such as kitchen detergents, laundry detergents, and detergents, as well as cosmetics.

Hereinafter, the present specification will be described in more detail.

A detailed description of this is as follows. Meanwhile, each description and embodiment disclosed in the present invention may also be applied to other descriptions and embodiments for each. That is, all combinations of the various elements disclosed herein fall within the scope of the present invention. In addition, it cannot be seen that the scope of the present invention is limited by the specific descriptions described below.

Expressions such as “comprising” used in this specification are understood as open-ended terms that include the possibility of including other embodiments, unless specifically stated otherwise in a phrase or sentence in which the expression is included. It should be.

The terms or words used in the description and claims of the present invention should not be construed as being limited to ordinary or dictionary meanings, and the inventors use the concept of terms appropriately in order to explain their invention in the best way. Based on the principle that it can be defined, it should be interpreted as meaning and concept consistent with the technical spirit of the present invention.

liquid composition

The present invention provides a liquid composition comprising (a) an alkylpolyglucoside nonionic surfactant represented by Formula 1; and (b) an alkylglucose carboxylate salt anionic surfactant represented by Formula 2.

[Formula 1]

[Formula 2]

In Formula 1,

m is an integer from 1 to 5;

n is an integer from 5 to 17;

In Formula 2,

R is C ₈ to C ₁₈ alkyl;

p is an integer from 1 to 5;

M is sodium.

In the present invention, the term "alkylpolyglucoside nonionic surfactant" refers to a nonionic surfactant derived from a common natural organic monomer found in starch, fat and sugar, most preferably derived from a D-glucose monomer. means surfactant.

In the present invention, the term "alkylglucose carboxylate salt anionic surfactant" refers to a naturally-derived anionic surfactant made by combining an aliphatic alcohol extracted from coconut with glucose.

In the present invention, the alkylpolyglucoside nonionic surfactant represented by Formula 1 and the alkylglucose carboxylate salt anionic surfactant represented by Formula 2 have a weight ratio of 7.5:2.5 to 9.5:0.5, preferably 8: It may be included in a weight ratio of 2 to 9: 1, but is not limited thereto.

The inventors of the present invention studied an alkyl polyglucoside nonionic surfactant represented by Formula 1 developed to replace existing sodium lauryl sulfate (SLS) and sodium laureth sulfate (SLES) anionic surfactants. When the alkyl polyglucoside nonionic surfactant represented by Chemical Formula 1 is used alone, deterioration in detergency, foaming power, and rinsing properties occur, making it difficult to apply to various household chemical products and cosmetics.

Under these circumstances, the inventors of the present invention found that when another nonionic surfactant, an alkylglucose carboxylate salt anionic surfactant represented by Formula 2, is combined with an alkylpolyglucoside nonionic surfactant represented by Formula 1, the detergency , foaming power and rinsability can be remarkably improved, and the present invention has been completed.

At this time, the combination ratio of the alkyl polyglucoside nonionic surfactant represented by Formula 1 and the alkylglucose carboxylate salt anionic surfactant represented by Formula 2 is also an important factor. , there is a problem that the foaming power and rinsability are reduced.

Therefore, it is necessary to combine the alkyl polyglucoside nonionic surfactant represented by Formula 1 and the anionic alkylglucose carboxylate salt anionic surfactant represented by Formula 2 in an optimal weight ratio to solve the previously pointed out problems. In the liquid composition of the present invention, the weight ratio of the alkylpolyglucoside nonionic surfactant represented by Chemical Formula 1 and the alkylglucose carboxylate salt anionic surfactant represented by Chemical Formula 2 can be regarded as a means for solving the problems of the present invention.

Expressed in another way, the liquid composition of the present invention contains 7.5 to 9.5% by weight of an alkyl polyglucoside nonionic surfactant represented by Formula 1 based on the weight of the total liquid composition, and an anion of an alkylglucose carboxylate represented by Formula 2 It may be a liquid composition consisting of 0.5 to 2.5% by weight of a surfactant and the rest purified water.

In the present invention, in the alkyl polyglucoside nonionic surfactant represented by Formula 1, m may be an integer of 1 to 3, and n may be an integer of 7 to 13, but is not limited thereto.

In the present invention, in the alkylglucose carboxylate salt anionic surfactant represented by Formula 2, R is C ₁₀ to C ₁₄ alkyl, p is an integer of 1 to 3, and M may be sodium, limited thereto it is not going to be

In the present invention, the alkyl polyglucoside nonionic surfactant represented by Formula 1 may be any one selected from the group consisting of decyl glucoside, lauryl glucoside, myristyl glucoside and mixtures thereof, and is limited thereto It is not.

In particular, among the alkyl polyglucoside nonionic surfactants represented by Formula 1, decyl glucoside (synonym: D-Glucopyranose, oligomeric, C8-16-alkyl glycosides, CAS No.141464-42-8) has the following formula As a nonionic surfactant represented by 1-1, it has the best detergency and foaming power.

[Formula 1-1]

(In the decyl glucoside represented by Formula 1-1, m is an integer of 1 and n is an integer of 9 in Formula 1.)

In addition, among the alkyl polyglucoside nonionic surfactants represented by Formula 1, lauryl glucoside (CAS No. 59122-55-3) is a nonionic surfactant represented by Formula 1-2 below, and has a detergency There is an advantage that the foaming force is the best.

[Formula 1-2]

(In the lauryl glucoside represented by Chemical Formula 1-2, m is an integer of 1 and n is an integer of 11 in Chemical Formula 1.)

In addition, among the alkyl polyglucoside nonionic surfactants represented by Formula 1, myristyl glucoside (Synonym: n-Tetradecyl D-glucoside, CAS No. 54549-26-7) is represented by the following Formula 1-3 As a nonionic surfactant, it has the best detergency and foaming power.

[Formula 1-3]

In the present invention, when the alkyl polyglucoside nonionic surfactant represented by Formula 1 corresponds to a mixture of decyl glucoside, lauryl glucoside and/or myristyl glucoside, (1) a combination of decyl glucoside and lauryl glucoside; (2) a combination of decyl glucoside and myristyl glucoside, (3) a combination of lauryl glucoside and myristyl glucoside, (4) a combination of decyl glucoside, lauryl glucoside and myristyl glucoside.

Specifically, (1) when the alkyl polyglucoside nonionic surfactant represented by Formula 1 is a mixture of decyl glucoside and lauryl glucoside, the weight ratio of decyl glucoside and lauryl glucoside is 3.5: 6.5 to 6.5: 3.5 It may be mixed, preferably in a weight ratio of 4.5: 5.5 to 5.5: 4.5, but is not limited thereto.

In addition, (2) when the alkyl polyglucoside nonionic surfactant represented by Formula 1 is a mixture of decyl glucoside and myristyl glucoside, decyl glucoside and myristyl glucoside are mixed at a weight ratio of 3.5: 6.5 to 6.5: 3.5. It may be, preferably mixed in a weight ratio of 4.5: 5.5 ~ 5.5: 4.5, but is not limited thereto.

In addition, (3) when the alkyl polyglucoside nonionic surfactant represented by Formula 1 is a mixture of lauryl glucoside and myristyl glucoside, the weight ratio of lauryl glucoside and myristyl glucoside is 3.5: 6.5 to 6.5: 3.5 It may be mixed, preferably in a weight ratio of 4.5: 5.5 to 5.5: 4.5, but is not limited thereto.

In addition, (4) When the alkyl polyglucoside nonionic surfactant represented by Formula 1 is a mixture of decyl glucoside, lauryl glucoside and myristyl glucoside, the mixture is mixed at a weight ratio of 1: 1: 1 to 2: 1: 1 It may have been, but is not limited thereto.

In the present invention, the alkylglucose carboxylate salt anionic surfactant represented by Formula 2 is sodium decyl glucose carboxylate, sodium lauryl glucose carboxylate, sodium myristyl It may be any one selected from the group consisting of glucose carboxylate (Sodium Myristyl Glucose Carboxylate) and mixtures thereof, but is not limited thereto.

(The myristyl is synonymous with n-tetradecyl.)

In particular, the alkylglucose carboxylate salt anionic surfactant represented by Formula 2 is sodium lauryl glucose carboxylate represented by Formula 2-1 below, and has excellent detergency and foaming power.

[Formula 2-1]

(In the sodium lauryl glucose carboxylate represented by Formula 2-1, in Formula 2, p is an integer of 1, and R is a lauryl group (-(CH ₂ ) ₁₁ CH ₃ ).)

In addition, the alkylglucose carboxylate salt anionic surfactant represented by Chemical Formula 2 is sodium decyl glucose carboxylate represented by Chemical Formula 2-2, and has excellent detergency and foaming power.

[Formula 2-2]

(In the sodium decyl glucose carboxylate represented by Formula 2-2, in Formula 2, p is an integer of 1, and R is a decyl group (-(CH ₂ ) ₉ CH ₃ ).)

In addition, the alkylglucose carboxylate salt anionic surfactant represented by Formula 2 is sodium myristyl glucose carboxylate represented by Formula 2-3 below, and has excellent detergency and foaming power.

[Formula 2-3]

(In the sodium myristyl glucose carboxylate represented by Formula 2-3, in Formula 2, p is an integer of 1, and R is a myristyl group (-(CH ₂ ) ₁₃ CH ₃ ).)

In the present invention, when the alkylglucose carboxylate salt anionic surfactant represented by Formula 2 corresponds to a mixture of sodium decyl glucose carboxylate, sodium lauryl glucose carboxylate and/or sodium myristyl glucose carboxylate (1 ) a combination of sodium decyl glucose carboxylate and sodium lauryl glucose carboxylate, (2) a combination of sodium decyl glucose carboxylate and sodium myristyl glucose carboxylate, (3) a combination of sodium lauryl glucose carboxylate and sodium myristyl glucose carboxylate (4) a combination of sodium decyl glucose carboxylate, sodium lauryl glucose carboxylate and sodium myristyl glucose carboxylate.

Specifically, (1) in the case of a combination of sodium decyl glucose carboxylate and sodium lauryl glucose carboxylate, they may be mixed at a weight ratio of 3.5:6.5 to 6.5:3.5.

(2) In the case of a combination of sodium decyl glucose carboxylate and sodium myristyl glucose carboxylate, they may be mixed in a weight ratio of 3.5:6.5 to 6.5:3.5.

(3) In the case of a combination of sodium lauryl glucose carboxylate and sodium myristyl glucose carboxylate, they may be mixed in a weight ratio of 3.5:6.5 to 6.5:3.5.

(4) In the case of a combination of sodium decyl glucose carboxylate, sodium lauryl glucose carboxylate, and sodium myristyl glucose carboxylate, they may be mixed in a weight ratio of 1:1:1 to 2:1:1.

Products containing liquid compositions

The present invention provides a product containing the liquid composition.

In the present invention, the product may be a sanitary product, a household chemical product, or a cosmetic product, but is not limited thereto.

In the present invention, the term "sanitary products" means products that require special hygiene management in order to ensure health hygiene.

In the present invention, the term "daily chemical product" refers to a chemical product used in everyday living spaces such as homes, offices, and multi-use facilities, which may cause exposure of chemicals to people or the environment.

In the present invention, the term "cosmetics" is used in a similar way, such as applying to the human body, rubbing, spraying, etc., to clean and beautify the human body to add charm and brighten the appearance, or to maintain or promote the health of the skin and hair. It refers to a product that has a slight effect on the human body.

In the present invention, according to the Sanitary Product Management Act, the sanitary product may be one selected from the group consisting of dish detergent, dishwasher detergent, fruit or vegetable detergent, and wet tissue, but is not limited thereto.

In the present invention, according to the Act on the Safety Management of Household Chemical Products and Biocides, the household chemical products are laundry detergents for clothes, residential space cleaners, deodorants, air cleaners, room fragrances, flavoring agents, and multi-purpose cleaners (bathroom cleaners). , mold remover, oil stain remover, kitchen cleaner, etc.), disinfectant, and disinfectant may be selected from the group consisting of, but is not limited thereto.

In the present invention, the cosmetic may be prepared in any formulation commonly prepared in the art according to the Cosmetics Act, and may be prepared as a solution, suspension, emulsion, paste, gel, cream, lotion, fact, powder, soap, surfactant- It may be formulated in any one selected from the group consisting of containing cleansing, oil, emulsion foundation, wax foundation and spray, but is not limited thereto.

In the present invention, the cosmetics may be any one or more selected from the group consisting of soap, shampoo, rinse, cleansing foam, cleansing lotion, cleansing water, cleansing cream, and body cleanser, but is not limited thereto.

In the present invention, the product may be at least one selected from the group consisting of kitchen detergent, laundry detergent, detergent, deodorant, fragrance, shampoo, rinse, body wash, hand soap, face wash, and soap, but is not limited thereto.

In the present invention, when the liquid composition is used in sanitary products such as dishwashing detergent, laundry detergent, or cleaning agent, or household chemical products, it may include not only the liquid composition but also agents for exhibiting cleaning and cleaning activities. The specific formulation is defined as including all of the configurations and mixing ranges that can be selected and mixed by those skilled in the art.

In the present invention, when the liquid composition is used in cosmetics such as shampoo, rinse, body wash, hand soap, face wash or soap, not only the liquid composition but also an abrasive, a viscosity modifier, a viscosity increasing agent, a stabilizer, an antifoaming agent, and an antioxidant , buffering agent, solvent, etc., and its specific type can be used in various ways as long as it can be used in general cosmetics.

In the present invention, the liquid composition may be included in an amount of 0.01 to 10% by weight based on the total weight of sanitary products, household chemical products, or cosmetics, but is not limited thereto.

Matters mentioned in the liquid composition and products containing the liquid composition of the present invention are equally applied unless contradictory to each other.

Hereinafter, the present invention was evaluated by applying it to various products so that those skilled in the art can easily implement the present invention with reference to preferred embodiments. However, the present invention may be embodied in many different forms and is not limited to the examples described below.

Example

Example 1.

Decyl glucoside represented by Chemical Formula 1-1 and lauryl glucoside represented by Chemical Formula 1-2 are mixed in a weight ratio of 4.5 : 5.5 Alkyl polyglucoside nonionic surfactant and sodium lauryl glucose represented by Chemical Formula 2-1 A liquid composition was prepared by mixing the carboxylate with purified water in a weight ratio of 9:1.

Example 2.

Decyl glucoside represented by Chemical Formula 1-1 and lauryl glucoside represented by Chemical Formula 1-2 are mixed in a weight ratio of 4.5 : 5.5 Alkyl polyglucoside nonionic surfactant and sodium lauryl glucose represented by Chemical Formula 2-1 Carboxylate was mixed with purified water in a weight ratio of 8:2 to prepare a liquid composition.

comparative example

Comparative Example 1.

A liquid composition was prepared by mixing only alkyl polyglucoside nonionic surfactants in which decyl glucoside represented by Chemical Formula 1-1 and lauryl glucoside represented by Chemical Formula 1-2 were mixed in a weight ratio of 4.5:5.5 with purified water.

Comparative Example 2.

A liquid composition was prepared by mixing only sodium lauryl glucose carboxylate represented by Chemical Formula 2-1 with purified water.

Comparative Example 3.

Decyl glucoside represented by Chemical Formula 1-1 and lauryl glucoside represented by Chemical Formula 1-2 are mixed in a weight ratio of 4.5 : 5.5 Alkyl polyglucoside nonionic surfactant and sodium lauryl glucose represented by Chemical Formula 2-1 Carboxylate was mixed with purified water in a weight ratio of 7:3 to prepare a liquid composition.

Comparative Example 4.

Decyl glucoside represented by Chemical Formula 1-1 and lauryl glucoside represented by Chemical Formula 1-2 are mixed in a weight ratio of 4.5 : 5.5 Alkyl polyglucoside nonionic surfactant and sodium lauryl glucose represented by Chemical Formula 2-1 Carboxylate was mixed with purified water in a weight ratio of 3:7 to prepare a liquid composition.

Comparative Example 5.

Decyl glucoside represented by Chemical Formula 1-1 and lauryl glucoside represented by Chemical Formula 1-2 are mixed in a weight ratio of 4.5 : 5.5 Alkyl polyglucoside nonionic surfactant and sodium lauryl glucose represented by Chemical Formula 2-1 A liquid composition was prepared by mixing the carboxylate with purified water in a weight ratio of 5:5.

Comparative Example 6.

A liquid composition was prepared by mixing only sodium laureth sulfate (SLES) with purified water.

Example 1 Example 2 Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 Comparative Example 6 ingredient APG 9 8 10 0 7 3 5 - AGC One 2 0 10 3 7 5 - SLES - - - - - - - 10 Purified water 90 90 90 90 90 90 90 90

(In Table 1, APG is an alkyl polyglucoside nonionic surfactant in which decyl glucoside represented by Chemical Formula 1-1 and lauryl glucoside represented by Chemical Formula 1-2 are mixed in a weight ratio of 4.5: 5.5, and AGC is chemical formula Sodium lauryl glucose carboxylate represented by 2-1, SLES is sodium laureth sulfate, and the unit of content of each component is weight%, and weight% is expressed based on the weight of the entire liquid composition.)

Experimental example

Experimental Example 1. Evaluation of detergency

(1) Evaluation method

In order to evaluate the detergency of the liquid compositions according to Examples 1 and 2 and Comparative Examples 1 to 6, a method for removing contaminants in a water system was selected. Contaminants were oleic acid, oleic acid salt, triolein, cholesterol, liquid paraffin, squalene, gelatin, red-yellow clay, and carbon black contaminants. The washing power was determined using a wet artificial soiling cloth of the JIS C 9606 standard of the Japan Laundry Science Association. , the wet artificial pollution cloths used were 5 cm x 5 cm in size, and 8 sheets were used per sample.

The detergency test method was operated under the conditions of 100 revolutions per minute (100 r/min) at 25 ° C using a detergency tester (Terg-O-Tomer; T.O.T), and the sample amount was Examples 1 and 2, Comparative Examples 1 to 2 10 g/L of the liquid composition according to No. 6 was used, washing time was 10 minutes, rinsing was done twice for 3 minutes each, and after drying for 5 minutes, a colorimeter (Konica Minolta Co.) was used. In addition, when measuring the value, the whiteness was calculated by measuring the central part of the front and back of the test cloth, respectively, and calculated based on Equation 1 below, and the results are shown in Table 2 below.

[Equation 1]

Detergency (%) = {(C-B)/(A-B)}×100

A: Whiteness of white cloth

B: Whiteness of contaminated cloth before washing

C: Whiteness of contaminated cloth after washing

(2) Evaluation results

Example 1 Example 2 Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 Comparative Example 6 castle
minute APG 9 8 10 0 7 3 5 - AGC One 2 0 10 3 7 5 - SLES - - - - - - - 10 Purified water 90 90 90 90 90 90 90 90 cleaning power
(%) 28.3 29.5 25.4 25.9 27.5 26.4 27.2 29.3

(Description of abbreviations in Table 2 is the same as that described in Table 1.)

Referring to Table 2, it can be seen that the cleaning power of the liquid compositions of Examples 1 and 2 according to the present invention is superior to that of the liquid compositions of Comparative Examples 1 to 5. In particular, in Comparative Examples 1 and 2, an alkyl polyglucoside nonionic surfactant in which decyl glucoside represented by Chemical Formula 1-1 and lauryl glucoside represented by Chemical Formula 1-2 are mixed, and represented by Chemical Formula 2-1 It can be seen that there is a difference in detergency depending on the presence or absence of the combination of sodium lauryl glucose carboxylate.

In addition, in Comparative Examples 3 to 5, an alkyl polyglucoside nonionic surfactant in which decyl glucoside represented by Chemical Formula 1-1 and lauryl glucoside represented by Chemical Formula 1-2 are mixed, and represented by Chemical Formula 2-1 It can be seen that there is a difference in detergency according to the weight ratio when the sodium lauryl glucose carboxylate is combined. That is, even if the same material is used, it can be seen that there is a difference in detergency due to a difference in weight ratio.

In addition, it was confirmed that the liquid compositions of Examples 1 and 2 according to the present invention are at the same level as the liquid composition of Comparative Example 6 in terms of detergency, while showing the same level of detergency as the liquid composition according to Comparative Example 6 containing SLES It can also be confirmed that the liquid composition has low skin irritation and low cytotoxicity.

Experimental Example 2. Evaluation of foaming force

(1) Evaluation method

In order to measure the foaming force of the compositions of Examples and Comparative Examples, 250 mL of the 0.1% liquid composition was put into a 500 mL measuring cylinder and a rotor of a foam tester (SITA foam tester R-2000, manufacturer: SITA Messtechnik GmbH) The mixture was stirred at 1500 rpm for 1 minute to generate bubbles. After stopping the rotor, the volume (mL) of bubbles generated was measured, and the results are shown in Table 3.

(2) Evaluation results

Example 1 Example 2 Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 Comparative Example 6 castle
minute APG 9 8 10 0 7 3 5 - AGC One 2 0 10 3 7 5 - SLES - - - - - - - 10 Purified water 90 90 90 90 90 90 90 90 bubble power
(ml) 160 155 60 130 117 145 134 158

(Description of abbreviations in Table 3 is the same as that described in Table 1.)

Referring to Table 3, it can be seen that the foaming power of the liquid compositions of Examples 1 and 2 according to the present invention is superior to that of the liquid compositions of Comparative Examples 1 to 5. In particular, in Comparative Examples 1 and 2, an alkyl polyglucoside nonionic surfactant in which decyl glucoside represented by Chemical Formula 1-1 and lauryl glucoside represented by Chemical Formula 1-2 are mixed, and represented by Chemical Formula 2-1 It can be seen that there is a difference in foaming power depending on the presence or absence of the combination of sodium lauryl glucose carboxylate to be.

In addition, in Comparative Examples 3 to 5, an alkyl polyglucoside nonionic surfactant in which decyl glucoside represented by Chemical Formula 1-1 and lauryl glucoside represented by Chemical Formula 1-2 are mixed, and represented by Chemical Formula 2-1 It can be seen that there is a difference in foaming power according to the weight ratio when combining sodium lauryl glucose carboxylate to be. That is, it can be seen that even if the same material is used, there is a difference in foaming force due to a difference in weight ratio.

In addition, it was confirmed that the liquid compositions of Examples 1 and 2 according to the present invention were at the same level as the liquid composition of Comparative Example 6 in terms of foaming power, and the liquid composition according to Comparative Example 6 containing SLES had foaming power equivalent to that of the liquid composition of Comparative Example 6. It can be confirmed that the liquid composition has low skin irritation and low cytotoxicity while showing.

Experimental Example 3. Evaluation of rinseability

(1) Evaluation method

As a method for rinsing evaluation, soil prepared from tallow, lard, and soybean oil at a ratio of 1:1:1 was uniformly applied to 5 slide glasses. Using an agitation type washer, 1 g of the liquid composition of Examples and Comparative Examples was added to 1 L of purified water, washed at a speed of 100 rpm for 5 minutes, and the feeling of rubbing the wiped slide glass by hand was as shown in Table 4. As a standard, sensory evaluation was performed on 20 panelists, and the averaged result values are shown in Table 5.

mark Crispy Judgment - very soft + soft ++ slightly slippery +++ slipperiness

(2) Evaluation results

Example 1 Example 2 Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 Comparative Example 6 castle
minute APG 9 8 10 0 7 3 5 - AGC One 2 0 10 3 7 5 - SLES - - - - - - - 10 Purified water 90 90 90 90 90 90 90 90 rinseability - - +++ + ++ + + ++

(Description of abbreviations in Table 5 is the same as that described in Table 1.)

Referring to Table 5, it can be seen that the rinsing properties of the liquid compositions of Examples 1 and 2 according to the present invention are superior to those of the liquid compositions of Comparative Examples 1 to 6. In particular, in Comparative Examples 1 and 2, an alkyl polyglucoside nonionic surfactant in which decyl glucoside represented by Chemical Formula 1-1 and lauryl glucoside represented by Chemical Formula 1-2 are mixed, and represented by Chemical Formula 2-1 It can be seen that there is a difference in rinseability depending on the presence or absence of the combination of sodium lauryl glucose carboxylate.

In addition, in Comparative Examples 3 to 5, an alkyl polyglucoside nonionic surfactant in which decyl glucoside represented by Chemical Formula 1-1 and lauryl glucoside represented by Chemical Formula 1-2 are mixed, and represented by Chemical Formula 2-1 It can be seen that there is a difference in rinseability according to the weight ratio when the sodium lauryl glucose carboxylate is combined. That is, it can be seen that there is a difference in rinseability due to a difference in weight ratio even when the same material is used.

In addition, it was confirmed that the liquid compositions of Examples 1 and 2 according to the present invention were superior in terms of rinseability to the liquid composition of Comparative Example 6, and the liquid composition according to Comparative Example 6 containing SLES had excellent detergency and foaming power Even if it was shown, it can be confirmed that there is difficulty in using it as a detergent due to poor rinseability.

Therefore, it can be confirmed that the liquid compositions of Examples 1 and 2 according to the present invention are liquid compositions having excellent ability as detergents and low skin irritation and low cell toxicity compared to the liquid composition of Comparative Example 6.

Experimental Example 4. Evaluation of skin irritation

(1) Evaluation method

32 adult men and women between the ages of 20 and 60 were selected as test subjects, and the test site of the test subject was wiped with 70% ethanol, dried, and IQ loaded with 20 μL of the 0.5% liquid composition of Examples and Comparative Examples. An Ultra patch was attached to the back and fixed with 3M Micropore Tape. After 24 hours of patch attachment, it was removed, and after 1 hour, the first degree of skin irritation was evaluated by visual evaluation, and the second degree of skin irritation was evaluated after 24 hours of patch removal. The criterion for determining the degree of irritation on the skin was scored by the symptoms in Table 6 according to the criteria of Frosch & Kligman and Colipa guideline, which applied the reading criteria of the International Contact Determatitis Research Group (ICDRG), and The results are shown in Table 8 according to the criteria.

[Equation 2]

Average skin reactivity = ∑(reactive subjects * grade) * 100 / (maximum grade * total number of subjects) / 2

mark Rating standard - 0.0 No reaction (Negative) ± 0.5 mild erythema + One Mild erythema, edema, papules ++ 2 Marked erythema with edema +++ 3 cannon

average skin reactivity skin irritation index 0.0 - 0.9 hypoallergenic 1.0 - 2.9 light stimulation 3.0 - 4.9 moderate stimulation 5.0 or higher strong stimulation

(2) Evaluation results

Example 1 Example 2 Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 Comparative Example 6 castle
minute APG 9 8 10 0 7 3 5 - AGC One 2 0 10 3 7 5 - SLES - - - - - - - 10 Purified water 90 90 90 90 90 90 90 90 skin irritation index hypoallergenic hypoallergenic hypoallergenic hypoallergenic hypoallergenic hypoallergenic hypoallergenic light stimulation

(Description of abbreviations in Table 8 is the same as that described in Table 1.)

When the liquid composition of Comparative Example 6 was applied to a detergent product, it was predicted as a test product with a high possibility of causing significant skin irritation.

That is, it can be confirmed that the liquid compositions of Examples 1 and 2 according to the present invention have low skin irritation compared to the liquid composition containing SLES of Comparative Example 6.

Experimental Example 5. Cytotoxicity evaluation

(1) Evaluation method

Cell toxicity was evaluated at a concentration of 0.1% of the liquid composition according to Examples and Comparative Examples for skin fibroblasts. For the evaluation of cytotoxicity, fibroblasts were cultured by adding 10% Fetal Bovine Serum (FBS) to DMEM (Dulbecco's Modified Eagle's Medium) as a basal medium. Cytotoxicity was performed using the 3-(4,5-dimethythiazol-2-yl)-2,5-diphenyl tetrazolium bromide (hereinafter referred to as 'MTT') method. Using DMEM medium supplemented with 10% FBS, cell lines were seeded on a 48 WELL PLATE at a concentration of 2-5 x 10 ⁴ cells/ml and cultured for 24 hours in a 5% CO₂incubator. The sample was replaced with a diluted new medium and cultured for 24 hours. Thereafter, the medium was removed, and MTT solution was added at a concentration of 1 μg/ml, followed by reaction at 37° C. for 3 hours. After removing the unreacted MTT solution and dissolving the reactant formed by adding 100 μL of DMSO (Dimethyl Sulfoxide), the absorbance was measured at 540 nm to confirm the cytotoxicity of the sample, and it is shown in Table 9.

(2) Evaluation results

Example 1 Example 2 Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 Comparative Example 6 castle
minute APG 9 8 10 0 7 3 5 - AGC One 2 0 10 3 7 5 - SLES - - - - - - - 10 Purified water 90 90 90 90 90 90 90 90 Cell viability (%) 68.25 68.94 53.13 67.52 61.25 66.17 63.15 31.54

(Description of abbreviations in Table 9 is the same as that described in Table 1.)

Referring to Table 9, it can be seen that the cell viability of the liquid compositions of Examples 1 and 2 according to the present invention is superior to that of the liquid compositions of Comparative Examples 1 to 6. In particular, in Comparative Examples 1 and 2, an alkyl polyglucoside nonionic surfactant in which decyl glucoside represented by Chemical Formula 1-1 and lauryl glucoside represented by Chemical Formula 1-2 are mixed, and represented by Chemical Formula 2-1 It can be seen that there is a difference in cell viability depending on the presence or absence of the combination of sodium lauryl glucose carboxylate to be used.

In addition, in Comparative Examples 3 to 5, an alkyl polyglucoside nonionic surfactant in which decyl glucoside represented by Chemical Formula 1-1 and lauryl glucoside represented by Chemical Formula 1-2 are mixed, and represented by Chemical Formula 2-1 It can be seen that there is a difference in cell viability depending on the weight ratio when the sodium lauryl glucose carboxylate is combined. That is, even if the same material is used, it can be seen that there is a difference in cell viability due to a difference in weight ratio.

In addition, when the liquid composition of Comparative Example 6 was applied to detergent products, it was predicted as a test product with a high possibility of causing significant cytotoxicity.

That is, it can be confirmed that the liquid compositions of Examples 1 and 2 according to the present invention have low cytotoxicity compared to the liquid composition containing SLES of Comparative Example 6.

Claims (10)

As a liquid composition,
(a) an alkyl polyglucoside nonionic surfactant represented by Formula 1; and
(b) A liquid composition comprising an anionic surfactant of an alkylglucose carboxylate salt represented by Formula 2:
[Formula 1]

[Formula 2]

In Formula 1,
m is an integer from 1 to 5;
n is an integer from 5 to 17;
In Formula 2,
R is C ₈ to C ₁₈ alkyl;
p is an integer from 1 to 5;
M is sodium.
According to claim 1,
A liquid composition comprising an alkylpolyglucoside nonionic surfactant represented by Formula 1 and an anionic alkylglucose carboxylate salt anionic surfactant represented by Formula 2 in a weight ratio of 7.5:2.5 to 9.5:0.5.
According to claim 1,
In the alkyl polyglucoside nonionic surfactant represented by Formula 1,
m is an integer from 1 to 3;
n is an integer of 7 to 13 liquid composition.
According to claim 1,
In the alkylglucose carboxylate salt anionic surfactant represented by Formula 2,
R is C ₁₀ to C ₁₄ alkyl;
p is an integer from 1 to 3;
A liquid composition in which M is sodium.
According to claim 1,
The alkyl polyglucoside nonionic surfactant represented by Formula 1,
A liquid composition that is any one selected from the group consisting of decyl glucoside, lauryl glucoside, myristyl glucoside, and mixtures thereof.
According to claim 1,
The alkylglucose carboxylate salt anionic surfactant represented by Formula 2,
Any one selected from the group consisting of Sodium Decyl Glucose Carboxylate, Sodium Lauryl Glucose Carboxylate, Sodium Myristyl Glucose Carboxylate, and mixtures thereof Phosphorus liquid composition.
A product comprising the liquid composition according to claim 1 .
According to claim 7,
The product is a sanitary product, a household chemical product, or a product that will be cosmetics.
According to claim 8,
The product is any one or more selected from the group consisting of kitchen detergent, laundry detergent, fabric softener, detergent, deodorant, fragrance, shampoo, conditioner, body wash, hand soap, face wash, and soap.
According to claim 8,
The liquid composition is a product characterized in that it comprises 0.01 to 10% by weight based on the weight of the total sanitary products, household chemical products or cosmetics.