KR20220152554A - 코로나바이러스-유도된 급성 호흡 곤란 증후군의 치료 및/또는 예방을 위해 masp-2를 억제하는 방법 - Google Patents

코로나바이러스-유도된 급성 호흡 곤란 증후군의 치료 및/또는 예방을 위해 masp-2를 억제하는 방법 Download PDF

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KR20220152554A
KR20220152554A KR1020227034690A KR20227034690A KR20220152554A KR 20220152554 A KR20220152554 A KR 20220152554A KR 1020227034690 A KR1020227034690 A KR 1020227034690A KR 20227034690 A KR20227034690 A KR 20227034690A KR 20220152554 A KR20220152554 A KR 20220152554A
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masp
alkyl
antibody
substituted
seq
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KR1020227034690A
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Korean (ko)
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그레고리 에이. 데모풀로스
티네카 제이. 퀸톤
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오메로스 코포레이션
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    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/451Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
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    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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KR1020227034690A 2020-03-06 2021-03-05 코로나바이러스-유도된 급성 호흡 곤란 증후군의 치료 및/또는 예방을 위해 masp-2를 억제하는 방법 KR20220152554A (ko)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US202062986566P 2020-03-06 2020-03-06
US62/986,566 2020-03-06
US202063008540P 2020-04-10 2020-04-10
US63/008,540 2020-04-10
US202063015299P 2020-04-24 2020-04-24
US63/015,299 2020-04-24
US202063054298P 2020-07-21 2020-07-21
US63/054,298 2020-07-21
US202063062843P 2020-08-07 2020-08-07
US63/062,843 2020-08-07
US202063104229P 2020-10-22 2020-10-22
US63/104,229 2020-10-22
US202063105637P 2020-10-26 2020-10-26
US63/105,637 2020-10-26
US202163140591P 2021-01-22 2021-01-22
US63/140,591 2021-01-22
PCT/US2021/021217 WO2021178902A1 (fr) 2020-03-06 2021-03-05 Procédés d'inhibition de masp -2 pour le traitement et/ou la prévention du syndrome de détresse respiratoire aiguë induite par le coronavirus

Publications (1)

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KR20220152554A true KR20220152554A (ko) 2022-11-16

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KR1020227034690A KR20220152554A (ko) 2020-03-06 2021-03-05 코로나바이러스-유도된 급성 호흡 곤란 증후군의 치료 및/또는 예방을 위해 masp-2를 억제하는 방법

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US (1) US20210292436A1 (fr)
EP (1) EP4114522A4 (fr)
JP (1) JP2023516727A (fr)
KR (1) KR20220152554A (fr)
CN (1) CN115335120A (fr)
AU (1) AU2021231892A1 (fr)
BR (1) BR112022016991A2 (fr)
CA (1) CA3169034A1 (fr)
IL (1) IL296240A (fr)
MX (1) MX2022010449A (fr)
TW (1) TW202319069A (fr)
WO (1) WO2021178902A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112237630A (zh) * 2020-02-21 2021-01-19 中国人民解放军军事科学院军事医学研究院 针对masp-2、冠状病毒n蛋白或其结合的物质在制备冠状病毒所致疾病药物中的应用
CN112023045A (zh) * 2020-03-31 2020-12-04 中国人民解放军军事科学院军事医学研究院 抑制masp-2及其下游补体活化效应的物质在制备冠状病毒所致疾病药物中的应用
WO2023174039A1 (fr) * 2022-03-18 2023-09-21 Inmagene Biopharmaceuticals (Hangzhou) Co., Ltd. Anticorps ciblant masp-2 et leurs utilisations
WO2024081269A1 (fr) * 2022-10-10 2024-04-18 Dixit Rohan Combinaisons thérapeutiques et méthodes de traitement de covid longue

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT2446900T (lt) * 2004-06-10 2017-07-25 Omeros Corporation Ligų, susijusių su nuo masp-2 priklausomu komplemento aktyvavimu, gydymo būdai
KR101641057B1 (ko) * 2011-05-04 2016-07-20 오메로스 코포레이션 Masp-2 의존적 보체 활성화를 억제하는 조성물
CN109908352A (zh) * 2012-06-18 2019-06-21 奥默罗斯公司 抑制masp-1和/或masp-2和/或masp-3的组合物和方法
EP2920592A4 (fr) * 2012-11-13 2016-07-06 Biogenius Llc Compositions et procédés de traitement de maladies inflammatoires d'origine infectieuse et non infectieuse
CN117964684A (zh) * 2018-05-29 2024-05-03 奥默罗斯公司 Masp-2抑制剂和使用方法
SG11202012627UA (en) * 2018-06-22 2021-01-28 Omeros Corp Compositions and methods of inhibiting masp-2 for the treatment of various thrombotic diseases and disorders
CN112237630A (zh) * 2020-02-21 2021-01-19 中国人民解放军军事科学院军事医学研究院 针对masp-2、冠状病毒n蛋白或其结合的物质在制备冠状病毒所致疾病药物中的应用
CN112023045A (zh) * 2020-03-31 2020-12-04 中国人民解放军军事科学院军事医学研究院 抑制masp-2及其下游补体活化效应的物质在制备冠状病毒所致疾病药物中的应用

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EP4114522A4 (fr) 2024-05-01
BR112022016991A2 (pt) 2022-12-06
WO2021178902A1 (fr) 2021-09-10
EP4114522A1 (fr) 2023-01-11
TW202146047A (zh) 2021-12-16
IL296240A (en) 2022-11-01
AU2021231892A1 (en) 2022-10-20
TW202319069A (zh) 2023-05-16
US20210292436A1 (en) 2021-09-23
CA3169034A1 (fr) 2021-09-10
JP2023516727A (ja) 2023-04-20
MX2022010449A (es) 2022-11-16
CN115335120A (zh) 2022-11-11

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