KR20220101184A - 침전물로부터 단백질을 추출하는 방법 및 불순물을 침전시키는 방법 - Google Patents

침전물로부터 단백질을 추출하는 방법 및 불순물을 침전시키는 방법 Download PDF

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Publication number
KR20220101184A
KR20220101184A KR1020227020996A KR20227020996A KR20220101184A KR 20220101184 A KR20220101184 A KR 20220101184A KR 1020227020996 A KR1020227020996 A KR 1020227020996A KR 20227020996 A KR20227020996 A KR 20227020996A KR 20220101184 A KR20220101184 A KR 20220101184A
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KR
South Korea
Prior art keywords
protein
interest
suspension
tank
permeate
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Pending
Application number
KR1020227020996A
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English (en)
Korean (ko)
Inventor
메냐위 이브라힘 엘
노르트하임 마르쿠스 폰
Original Assignee
체에스엘 베링 아게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Priority claimed from AU2019904386A external-priority patent/AU2019904386A0/en
Application filed by 체에스엘 베링 아게 filed Critical 체에스엘 베링 아게
Publication of KR20220101184A publication Critical patent/KR20220101184A/ko
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C07K1/32—Extraction; Separation; Purification by precipitation as complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
KR1020227020996A 2019-11-20 2020-11-20 침전물로부터 단백질을 추출하는 방법 및 불순물을 침전시키는 방법 Pending KR20220101184A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2019904386 2019-11-20
AU2019904386A AU2019904386A0 (en) 2019-11-20 Novel process
PCT/EP2020/082806 WO2021099529A1 (en) 2019-11-20 2020-11-20 Method for extracting a protein from a precipitate and method for precipitating impurities

Publications (1)

Publication Number Publication Date
KR20220101184A true KR20220101184A (ko) 2022-07-19

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020227020996A Pending KR20220101184A (ko) 2019-11-20 2020-11-20 침전물로부터 단백질을 추출하는 방법 및 불순물을 침전시키는 방법

Country Status (9)

Country Link
US (1) US12559520B2 (cg-RX-API-DMAC7.html)
EP (1) EP4061826A1 (cg-RX-API-DMAC7.html)
JP (1) JP2023502412A (cg-RX-API-DMAC7.html)
KR (1) KR20220101184A (cg-RX-API-DMAC7.html)
CN (1) CN114761417B (cg-RX-API-DMAC7.html)
AU (1) AU2020385637A1 (cg-RX-API-DMAC7.html)
CA (1) CA3157446A1 (cg-RX-API-DMAC7.html)
IL (1) IL293121A (cg-RX-API-DMAC7.html)
WO (1) WO2021099529A1 (cg-RX-API-DMAC7.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4408572B1 (en) * 2021-09-28 2026-07-01 LPS Biosolutions A/S IMPROVED PROTEIN SORTING AND FILTRATION DEVICE
CN116120435A (zh) * 2023-02-15 2023-05-16 山西康宝生物制品股份有限公司 一种从血浆组分fiii沉淀中制备静注人免疫球蛋白的方法
US20240284944A1 (en) * 2023-02-28 2024-08-29 Xiong Wei Filtration methods and associated food products prepared using the same

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE629149A (cg-RX-API-DMAC7.html) 1962-03-03
JPH0778025B2 (ja) 1990-03-20 1995-08-23 日本赤十字社 免疫グロブリンｇの製造方法
US5886154A (en) 1997-06-20 1999-03-23 Lebing; Wytold R. Chromatographic method for high yield purification and viral inactivation of antibodies
NZ513242A (en) 1999-02-22 2003-10-31 Henry B Kopf Purification of biological substances
US6214221B1 (en) * 1999-02-22 2001-04-10 Henry B. Kopf Method and apparatus for purification of biological substances
AU784808B2 (en) 2001-04-02 2006-06-29 Kedrion Melville Inc. Prion and viral clearance process
US6875459B2 (en) * 2001-09-10 2005-04-05 Henry B. Kopf Method and apparatus for separation of milk, colostrum, and whey
RU2005129745A (ru) * 2003-02-24 2006-03-20 Джитиси Байотерапьютикс, Инк. (Us) Способы и устройство проточной фильтрации вдоль потока
AU2003238273A1 (en) * 2003-06-17 2005-02-04 Centocor, Inc. Method and apparatus for filtration of bioreactor recombinant proteins
CN101415482B (zh) * 2006-03-31 2015-04-15 金克克国际有限公司 用于化合物分离的切向流动过滤设备、系统和方法
NZ589297A (en) 2008-05-15 2011-12-22 Health L P W Process for producing milk fractions rich in secretory immunoglobulins
AU2010202125B1 (en) 2010-05-26 2010-09-02 Takeda Pharmaceutical Company Limited A method to produce an immunoglobulin preparation with improved yield
CN103988973A (zh) * 2009-12-30 2014-08-20 索莱有限责任公司 大豆乳清蛋白组合物及其回收方法
TWI629283B (zh) 2012-02-23 2018-07-11 巴克斯歐塔公司 來自血漿中的免疫球蛋白之ｉ-ｉｖ-１部分沉澱
WO2015133972A1 (en) * 2014-03-07 2015-09-11 Agency For Science, Technology And Research Apparatus and methods for fractionation of biological products
CN105254754A (zh) * 2015-11-28 2016-01-20 上海洲跃生物科技有限公司 一种静注人免疫球蛋白（ph4）的制备方法
IL278584B2 (en) 2018-05-17 2025-08-01 Csl Behring Ag Method and system of protein extraction
CN108939922A (zh) 2018-08-07 2018-12-07 飞潮（无锡）过滤技术有限公司 一种旋转式陶瓷膜过滤分离工艺及装置

Also Published As

Publication number Publication date
US20230002444A1 (en) 2023-01-05
JP2023502412A (ja) 2023-01-24
IL293121A (en) 2022-07-01
CN114761417A (zh) 2022-07-15
US12559520B2 (en) 2026-02-24
CA3157446A1 (en) 2021-05-27
EP4061826A1 (en) 2022-09-28
CN114761417B (zh) 2026-06-02
WO2021099529A1 (en) 2021-05-27
AU2020385637A1 (en) 2022-06-09

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