KR20220052960A - 표적화된 덴드리머 접합체 - Google Patents

표적화된 덴드리머 접합체 Download PDF

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Publication number
KR20220052960A
KR20220052960A KR1020227008957A KR20227008957A KR20220052960A KR 20220052960 A KR20220052960 A KR 20220052960A KR 1020227008957 A KR1020227008957 A KR 1020227008957A KR 20227008957 A KR20227008957 A KR 20227008957A KR 20220052960 A KR20220052960 A KR 20220052960A
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South Korea
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conjugate
group
dendrimer
targeting agent
peg
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Korean (ko)
Inventor
데이빗 오웬
새미 체가예
수드히르 섄귤레
폴린 레이타노
크리스토퍼 포터
앵거스 존스턴
다니엘 유엔
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스타파마 피티와이 리미티드
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Priority claimed from AU2019903152A external-priority patent/AU2019903152A0/en
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Publication of KR20220052960A publication Critical patent/KR20220052960A/ko
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
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    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020227008957A 2019-08-28 2020-08-28 표적화된 덴드리머 접합체 Pending KR20220052960A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2019903152A AU2019903152A0 (en) 2019-08-28 Targeted Dendrimer Conjugates
AU2019903152 2019-08-28
PCT/AU2020/050910 WO2021035310A1 (en) 2019-08-28 2020-08-28 Targeted dendrimer conjugates

Publications (1)

Publication Number Publication Date
KR20220052960A true KR20220052960A (ko) 2022-04-28

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KR1020227008957A Pending KR20220052960A (ko) 2019-08-28 2020-08-28 표적화된 덴드리머 접합체

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US (1) US20220288216A1 (enExample)
EP (1) EP4021511A4 (enExample)
JP (2) JP2022547434A (enExample)
KR (1) KR20220052960A (enExample)
CN (1) CN114502201B (enExample)
AU (1) AU2020338481B2 (enExample)
BR (1) BR112022003628A2 (enExample)
CA (1) CA3149263A1 (enExample)
WO (1) WO2021035310A1 (enExample)

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US20180326081A1 (en) * 2011-06-06 2018-11-15 Starpharma Pty Ltd Macromolecules
JP7541978B2 (ja) * 2018-11-29 2024-08-29 スターファーマ ピーティーワイ エルティーディー 治療および画像化のためのデンドリマー
WO2023283537A2 (en) * 2021-07-07 2023-01-12 Institute For Systems Biology Cell analysis methods, compositions, and uses
EP4430076A2 (en) 2021-11-08 2024-09-18 Life Technologies AS Polymer-interaction molecule conjugates and methods of use
CN115991880B (zh) * 2022-12-08 2024-03-19 中国药科大学 一种树状大分子pamam-g5-tco及其制备方法与应用
WO2024182810A2 (en) * 2023-03-02 2024-09-06 Inmune Bio Inc. Bioconjugates of dominant negative tnf
KR20250100878A (ko) * 2023-12-26 2025-07-04 주식회사 압타머사이언스 분지형의 효소 절단 가능한 링커-페이로드와 이의 효율적인 제조방법
WO2025164814A1 (en) * 2024-02-01 2025-08-07 The University Of Tokyo Selective intracellular delivery of protein in cells with nanocarriers sensing cathepsin b activity
WO2025222234A1 (en) * 2024-04-24 2025-10-30 Starpharma Pty Ltd Targeted dendrimer conjugates
WO2026046228A1 (zh) * 2024-08-27 2026-03-05 苏州拓界医药有限公司 树枝状聚合物偶联物及其制备方法
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