KR20220052941A - T 세포 수용체 동정 방법 - Google Patents

T 세포 수용체 동정 방법 Download PDF

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Publication number
KR20220052941A
KR20220052941A KR1020227006937A KR20227006937A KR20220052941A KR 20220052941 A KR20220052941 A KR 20220052941A KR 1020227006937 A KR1020227006937 A KR 1020227006937A KR 20227006937 A KR20227006937 A KR 20227006937A KR 20220052941 A KR20220052941 A KR 20220052941A
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KR
South Korea
Prior art keywords
dpb1
drb1
amino acid
dqb1
seq
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Pending
Application number
KR1020227006937A
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English (en)
Korean (ko)
Inventor
나오토 히라노
무네히데 나카츠가와
유키 야마시타
켄지 수가타
무함메드 아시크 라만
Original Assignee
유니버시티 헬스 네트워크
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Publication of KR20220052941A publication Critical patent/KR20220052941A/ko
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56977—HLA or MHC typing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/32—T-cell receptors [TCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/7051—T-cell receptor (TcR)-CD3 complex
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70539—MHC-molecules, e.g. HLA-molecules

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020227006937A 2019-07-30 2020-07-29 T 세포 수용체 동정 방법 Pending KR20220052941A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962880492P 2019-07-30 2019-07-30
US62/880,492 2019-07-30
US202063029103P 2020-05-22 2020-05-22
US63/029,103 2020-05-22
PCT/IB2020/057176 WO2021019476A1 (en) 2019-07-30 2020-07-29 Methods of identifying t cell receptors

Publications (1)

Publication Number Publication Date
KR20220052941A true KR20220052941A (ko) 2022-04-28

Family

ID=74228602

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020227006937A Pending KR20220052941A (ko) 2019-07-30 2020-07-29 T 세포 수용체 동정 방법

Country Status (11)

Country Link
US (1) US20220291215A1 (enExample)
EP (1) EP4004546A4 (enExample)
JP (2) JP7724203B2 (enExample)
KR (1) KR20220052941A (enExample)
CN (1) CN114761802B (enExample)
AU (1) AU2020321710A1 (enExample)
CA (1) CA3146290A1 (enExample)
IL (1) IL290226A (enExample)
MX (1) MX2022001204A (enExample)
TW (1) TW202118779A (enExample)
WO (1) WO2021019476A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113795583B (zh) 2019-03-04 2026-03-27 大学健康网络 T细胞受体及其使用方法
WO2021019473A1 (en) 2019-07-30 2021-02-04 University Health Network Mhc class ii molecules and methods of use thereof
WO2021019475A1 (en) * 2019-07-30 2021-02-04 University Health Network Mhc class ii molecules and methods of use thereof
CN118662607A (zh) * 2023-03-15 2024-09-20 中国科学院上海巴斯德研究所 抑制过激炎性反应的蛋白及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012120488A (ja) * 2010-12-09 2012-06-28 Univ Of Tokyo 新規安定化組換えｍｈｃタンパク質
MX2020003117A (es) * 2017-09-20 2020-08-20 Us Health Receptores de celulas t restringidas a hla de clase ii contra ras mutado.

Also Published As

Publication number Publication date
MX2022001204A (es) 2022-05-03
IL290226A (en) 2022-03-01
JP2022542445A (ja) 2022-10-03
CA3146290A1 (en) 2021-02-04
WO2021019476A1 (en) 2021-02-04
AU2020321710A1 (en) 2022-03-03
JP7724203B2 (ja) 2025-08-15
TW202118779A (zh) 2021-05-16
CN114761802B (zh) 2026-04-28
EP4004546A1 (en) 2022-06-01
EP4004546A4 (en) 2024-10-09
CN114761802A (zh) 2022-07-15
JP2025166836A (ja) 2025-11-06
US20220291215A1 (en) 2022-09-15

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