KR20220044385A - 소양증을 치료하는 방법 - Google Patents

소양증을 치료하는 방법 Download PDF

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Publication number
KR20220044385A
KR20220044385A KR1020227010137A KR20227010137A KR20220044385A KR 20220044385 A KR20220044385 A KR 20220044385A KR 1020227010137 A KR1020227010137 A KR 1020227010137A KR 20227010137 A KR20227010137 A KR 20227010137A KR 20220044385 A KR20220044385 A KR 20220044385A
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KR
South Korea
Prior art keywords
per day
nalbuphine
pruritus
sustained release
delivery system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020227010137A
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English (en)
Korean (ko)
Inventor
토마스 시아시아
Original Assignee
트레비 테라퓨틱스, 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/715,625 external-priority patent/US8637538B1/en
Application filed by 트레비 테라퓨틱스, 인코포레이티드 filed Critical 트레비 테라퓨틱스, 인코포레이티드
Publication of KR20220044385A publication Critical patent/KR20220044385A/ko
Ceased legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/08Antiseborrheics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
KR1020227010137A 2012-12-14 2013-12-13 소양증을 치료하는 방법 Ceased KR20220044385A (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201261737488P 2012-12-14 2012-12-14
US13/715,625 US8637538B1 (en) 2012-12-14 2012-12-14 Methods for treatment of pruritis
US61/737,488 2012-12-14
US13/715,625 2012-12-14
PCT/US2013/075096 WO2014093871A1 (en) 2012-12-14 2013-12-13 Methods for treating pruritus
KR1020217012252A KR20210050585A (ko) 2012-12-14 2013-12-13 소양증을 치료하는 방법

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020217012252A Division KR20210050585A (ko) 2012-12-14 2013-12-13 소양증을 치료하는 방법

Publications (1)

Publication Number Publication Date
KR20220044385A true KR20220044385A (ko) 2022-04-07

Family

ID=50935003

Family Applications (3)

Application Number Title Priority Date Filing Date
KR1020227010137A Ceased KR20220044385A (ko) 2012-12-14 2013-12-13 소양증을 치료하는 방법
KR1020217012252A Ceased KR20210050585A (ko) 2012-12-14 2013-12-13 소양증을 치료하는 방법
KR1020157015561A Ceased KR20150093702A (ko) 2012-12-14 2013-12-13 소양증을 치료하는 방법

Family Applications After (2)

Application Number Title Priority Date Filing Date
KR1020217012252A Ceased KR20210050585A (ko) 2012-12-14 2013-12-13 소양증을 치료하는 방법
KR1020157015561A Ceased KR20150093702A (ko) 2012-12-14 2013-12-13 소양증을 치료하는 방법

Country Status (13)

Country Link
EP (1) EP2931279B1 (enExample)
JP (4) JP2016506398A (enExample)
KR (3) KR20220044385A (enExample)
CN (2) CN110585209A (enExample)
AU (2) AU2013359017B2 (enExample)
BR (1) BR112015013984A2 (enExample)
CA (1) CA2892393C (enExample)
ES (1) ES2984559T3 (enExample)
MX (1) MX2015007518A (enExample)
NZ (1) NZ708371A (enExample)
RU (1) RU2015128265A (enExample)
WO (1) WO2014093871A1 (enExample)
ZA (2) ZA201504229B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI433674B (zh) 2006-12-28 2014-04-11 Infinity Discovery Inc 環杷明(cyclopamine)類似物類
US20140179727A1 (en) 2012-12-14 2014-06-26 Trevi Therapeutics, Inc. Methods for treating pruritus
NZ708371A (en) * 2012-12-14 2020-05-29 Trevi Therapeutics Inc Methods for treating pruritus
US20150359789A1 (en) * 2014-06-13 2015-12-17 Trevi Therapeutics, Inc. Methods for treating pruritus
BR112017026103B1 (pt) 2015-06-04 2023-10-03 Sol-Gel Technologies Ltd Composições tópicas com composto inibidor de hedgehog, sistema de entrega tópica e seus usos
TW201725041A (zh) * 2016-01-04 2017-07-16 懷特生技新藥股份有限公司 治療皮膚癢之醫藥組合物
CN105560202B (zh) * 2016-03-11 2019-05-24 广州玻思韬控释药业有限公司 一种盐酸纳布啡凝胶骨架缓释片的制备方法及应用
AU2017238051B9 (en) * 2016-03-21 2022-11-03 Trevi Therapeutics, Inc. Treatment of uremic pruritus
AU2017350852A1 (en) * 2016-10-25 2019-04-11 Trevi Therapeutics, Inc. Treatment of prurigo nodularis
WO2018143423A1 (ja) * 2017-02-03 2018-08-09 株式会社東洋新薬 固形製剤
EP3826635A4 (en) * 2018-07-23 2022-04-27 Trevi Therapeutics, Inc. TREATMENT OF CHRONIC COUGH, SHORTNESS OF BREATH AND DYSPNEA
EP4087569A4 (en) 2020-01-10 2024-01-24 Trevi Therapeutics, Inc. METHODS OF ADMINISTRATION OF NALBUPHINE

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1310255B1 (en) * 1996-11-25 2004-04-07 Toray Industries, Inc. Antipruritic agent
US20030054030A1 (en) * 2001-09-13 2003-03-20 Gary Gordon Method and compositions for the treatment of pruritus
US6703398B2 (en) * 2001-11-26 2004-03-09 Oliver Yoa-Pu Hu Orally administered analgesic compositions containing nalbuphine
DE60325567D1 (de) * 2002-04-05 2009-02-12 Euro Celtique Sa Matrix für die modifizierte freigabe von aktiven substanzen
CA2566217A1 (en) * 2004-06-03 2005-12-15 Jonathan J. Burbaum Pharmaceutical compositions for the treatment of pruritus
PT1931315E (pt) * 2005-08-24 2014-01-03 Endo Pharmaceuticals Inc Formulações de libertação sustentada de nalbufina
US8394812B2 (en) * 2005-08-24 2013-03-12 Penwest Pharmaceuticals Co. Sustained release formulations of nalbuphine
FR2963889B1 (fr) * 2010-08-20 2013-04-12 Debregeas Et Associes Pharma Formulations a base de nalbuphine et leurs utilisations
NZ708371A (en) * 2012-12-14 2020-05-29 Trevi Therapeutics Inc Methods for treating pruritus

Also Published As

Publication number Publication date
KR20150093702A (ko) 2015-08-18
EP2931279A1 (en) 2015-10-21
RU2015128265A (ru) 2017-01-25
CN110585209A (zh) 2019-12-20
WO2014093871A1 (en) 2014-06-19
MX2015007518A (es) 2016-03-01
AU2018214098A1 (en) 2018-08-30
NZ708371A (en) 2020-05-29
CA2892393A1 (en) 2014-06-19
AU2018214098B2 (en) 2019-04-18
JP2021020947A (ja) 2021-02-18
ZA201906339B (en) 2021-07-28
CN104981246A (zh) 2015-10-14
EP2931279A4 (en) 2016-05-11
EP2931279B1 (en) 2024-03-20
JP7072280B2 (ja) 2022-05-20
HK1215541A1 (en) 2016-09-02
JP2022105095A (ja) 2022-07-12
JP2016506398A (ja) 2016-03-03
JP2019131588A (ja) 2019-08-08
AU2013359017B2 (en) 2018-05-10
AU2013359017A1 (en) 2015-06-11
ZA201504229B (en) 2021-07-28
BR112015013984A2 (pt) 2017-07-11
CA2892393C (en) 2021-06-08
KR20210050585A (ko) 2021-05-07
JP6823857B2 (ja) 2021-02-03
ES2984559T3 (es) 2024-10-29

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