KR20220011361A - Sticker type thermometer for fever measurement - Google Patents

Abstract

The present invention relates to a sticker-type thermometer for measuring fever. The sticker-type thermometer for measuring fever according to the present invention includes: a sheet layer; a body temperature indication layer formed on the sheet layer; an adhesive layer formed under the sheet layer and adhered thereto; and a release paper layer positioned under the adhesive layer to protect the adhesive layer. With the above configuration, the sticker-type thermometer for measuring fever according to the present invention can easily understand the temperature change of the skin through the change of color, may be stably fixed and attached to the skin of active infants, patients with mobility difficulties, or the elderly without any discomfort, and can easily grasp the state of the human body according to the body temperature.

Description

STICKER TYPE THERMOMETER FOR FEVER MEASUREMENT

The present invention relates to a sticker-type thermometer for measuring fever, and more particularly, it can easily detect changes in skin temperature through a change in color, and is stable even on the skin of active infants, patients with poor mobility, or the elderly without any discomfort. It relates to a sticker-type thermometer for measuring fever that is fixedly attached and can easily grasp the state of the human body according to body temperature.

Influenza and influenza, which occur frequently recently, are diseases that are accompanied by high fever. A thermometer that can efficiently detect high fever is needed.

In general, as a method for measuring body temperature, there are contact-type and non-contact thermometers, and examples of the general thermometer include mercury, alcohol, and an infrared sensor.

These thermometers can be measured only after waiting for a certain period of time while being worn or in contact with the body. Accordingly, in the case of infants, infants, and patients with reduced mobility, people around them can keep the thermometer worn on the patient's body. There was a cumbersome problem in measuring the body temperature because I had to help.

In addition, since the conventional thermometer is a method of checking the body temperature by separating it from the user's body after contacting the subject's body for a certain period of time, it is inconvenient to check the body temperature in real time or periodically. In the case of the elderly, there was a problem in that it was difficult to actively cope with changes in body temperature.

Domestic Registered Patent No. 10-2065661 (Registered on January 07, 2020) Domestic Patent Publication No. 10-2020-0049259 (published on May 08, 2020) Domestic Patent Publication No. 10-2012-0070413 (published on June 29, 2012)

The present invention can easily detect changes in skin temperature through color change, and it is stably fixed and attached to the skin of active infants, patients with limited mobility, or the elderly without any discomfort, so that it is possible to easily grasp the state of the human body according to body temperature. It is to provide a sticker-type thermometer for measuring fever.

Various problems to be solved by the present invention are not limited to the above-mentioned problems, and other problems not mentioned will be clearly understood by those skilled in the art from the following description.

A sticker-type thermometer for measuring fever according to the present invention includes a sheet backing layer; a body temperature indicator layer formed on the sheet support layer; an adhesive layer formed under the sheet support layer and adhered thereto; and a release paper layer positioned under the adhesive layer to protect the adhesive layer.

The body temperature indicator layer includes a first body temperature indicator layer and a second body temperature indicator layer, and the first body temperature indicator layer and the second body temperature indicator layer receive body temperature emitted from the skin of a person and receive a specific temperature within a certain temperature range. It may be configured to display a color.

The sheet paper layer is formed by mixing the sheet paper composition and then drying, the sheet paper composition is 1 to 5 parts by weight of copper nanoparticles, 1 to 3 parts by weight of gelite, 0.1 to 1 parts by weight of shell powder, 100 to 200 parts by weight of polyurethane resin It may be included in a weight ratio of 1 to 3 parts by weight and 1 to 3 parts by weight of the dispersant.

The body temperature indicator layer is first prepared by preparing a mixed solution in which a water-soluble ethylenically unsaturated monomer, a hydrophilic additive, an endothermic material, a natural plant extract, and a crosslinking agent are mixed in a certain weight ratio, and then glycerin and Zion pigment are added to the mixed solution, It can be prepared through a process of stirring for 20 to 40 minutes.

The mixed solution is mixed in a weight ratio of 50 to 80 parts by weight of a water-soluble ethylenically unsaturated monomer, 10 to 20 parts by weight of a hydrophilic additive, 5 to 10 parts by weight of a heat absorbing material, 1 to 3 parts by weight of a natural plant extract, and 2 to 6 parts by weight of a crosslinking agent. The glycerin and the Zion pigment may be included in a weight ratio of 5 to 10 parts by weight of glycerin and 1 to 5 parts by weight of the Zion pigment with respect to 100 parts by weight of the mixed solution.

The adhesive layer is formed by applying an adhesive composition to the lower portion of the sheet paper layer, wherein the adhesive composition includes 80 to 120 parts by weight of a polyurethane acrylate-based oligomer, 10 to 20 parts by weight of a solvent, and a bisphenol A type epoxy resin. It may be included in a weight ratio of 20 to 30 parts by weight, 5 to 10 parts by weight of polyvinyl alcohol, 1 to 2 parts by weight of natural rubber, and 0.1 to 1.5 parts by weight of antioxidant.

Specific details of other embodiments are included in the detailed description.

The sticker-type thermometer for measuring fever according to the present invention can easily detect changes in skin temperature through color change, and it is stably fixed and attached to the skin of active infants, patients with poor mobility, or the elderly without any sense of difference. The state of the human body can be easily grasped.

It will be fully understood that embodiments of the technical idea of the present invention may provide various effects not specifically mentioned.

1 is a diagram schematically showing a cross-section of a sticker-type thermometer for measuring fever according to the present invention.

Advantages and features of the present invention, and methods for achieving them, will become apparent with reference to the embodiments described below in detail. However, the present invention is not limited to the embodiments described herein and may be embodied in other forms. Rather, the embodiments introduced herein are provided so that the disclosed subject matter may be thorough and complete, and that the spirit of the present invention may be sufficiently conveyed to those skilled in the art.

The terms used in the present application are only used to describe specific embodiments, and are not intended to limit the present invention. The singular expression includes the plural expression unless the context clearly dictates otherwise.

Unless defined otherwise, all terms used herein, including technical or scientific terms, have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. Terms such as those defined in a commonly used dictionary should be interpreted as having a meaning consistent with the meaning in the context of the related art, and should not be interpreted in an ideal or excessively formal meaning unless explicitly defined in the present application. does not

Hereinafter, a preferred embodiment of the sticker-type thermometer for measuring fever according to the present invention will be described in detail with reference to the accompanying drawings.

1 is a diagram schematically showing a cross-section of a sticker-type thermometer for measuring fever according to the present invention.

Referring to FIG. 1 , a sticker type thermometer 10 for measuring fever according to the present invention includes a sheet backing layer 100 , a body temperature indicating layer 200 formed on the sheet backing layer 100 , and a lower portion of the sheet backing layer 100 . It includes an adhesive layer 300 that is formed and adhered, and a release paper layer 400 positioned below the adhesive layer 300 to protect the adhesive layer 300 .

The sheet backing layer 100 may be formed to fix the body temperature indicator layer 200 and transmit body temperature emitted from the skin of a person to the body temperature indicator layer 200, wherein the sheet backing layer 100 is polyurethane. It is formed in the form of a film prepared by using a resin, and the sheet paper layer 100 may be formed by mixing the sheet paper composition and then drying it.

The sheet composition may be included in a weight ratio of 1 to 5 parts by weight of copper nanoparticles, 1 to 3 parts by weight of gelite, 0.1 to 1 parts by weight of shell powder, 100 to 200 parts by weight of polyurethane resin, and 1 to 3 parts by weight of dispersant. .

The copper nanoparticles may be included to impart antibacterial and deodorizing properties, and the copper nanoparticles have antibacterial and deodorant properties, such as inhibiting the growth of bacteria and interfering with the metabolism of various microorganisms to remove the cause of unpleasant odors can be given

For example, copper oxide nanoparticles may be used as the copper nanoparticles, and the copper oxide nanoparticles are surface-modified by stirring 0.1 to 2 parts by weight of silane with respect to 100 parts by weight of copper oxide powder having a particle size of 1 to 200 nm. Copper oxide nanoparticles prepared by making it can be used.

That is, since the surface of the copper oxide powder is generally hydrophilic, it cannot be dispersed in the resin by OH groups and may coagulate with each other. By hydrolysis and bonding between the OH groups on the surface of the copper powder, the hydrophobic OR group in the silane is located on the surface of the copper oxide powder to improve dispersibility due to the repulsive force between the OR groups, that is, the repulsive force between the copper oxide powders.

In addition, the silane is vinyltriethoxysilane, vinyltrimethoxysilane, or vinyltri(2-methoxyethoxy)silane (Vinyltri(2-methoxyethoxy) to improve dispersibility as described above. silane) may be used, but the present invention is not necessarily limited thereto, and various known silanes may be used.

The Ge-lite is called pozzolan, and contains about 2.0 ppm of germanium and contains a large amount of far infrared rays and anions. Representative examples include volcanic ash, silicate clay, and silicate soil. That is, the gelite emits far-infrared rays equivalent to about 180 times that of loess to promote plant growth and has a humidity control function, emit negative ions and active energy to the human body, block harmful electromagnetic waves, and have deodorizing and sterilizing effects and It also provides a neutralizing effect of heavy metals.

The shell powder can be manufactured by pulverizing shells and pulverizing them. The shells are inorganic secretions that wrap and protect molluscs in molluscs, and these shells include abalone shells, petrified shells, clam shells, scallop shells, etc. When pulverized according to the type of shellfish, the texture and color appear very beautiful and diverse, and it has considerable thermal insulation performance due to the porous calcium component that is biochemically composed. It is known as a hygienic and eco-friendly material that has the ability to adsorb substances.

As the shell powder, shell powder prepared by the following method may be used.

First, the shell may be prepared and washed to remove foreign substances adhering to the shell.

As the shell, any one or more shells selected from the group consisting of abalone, oyster, conch, cockle, clam, petrified and clams may be used, and the washing of the shell is performed by washing the shell with sodium bicarbonate (NaHCO ₃ ) in purified water By washing the surface of the shell using the, it is possible to remove the foreign substances remaining on the surface of the shell.

The sodium bicarbonate (NaHCO ₃ ) is also used as a food additive, is non-toxic and has functions such as penetration, diffusion, and expansion to clean the surface of the shell, and the sodium bicarbonate is 3 to 5 (w /w)% concentration range, preferably washing for 5 to 15 minutes at a temperature of 25 to 35 ℃.

Next, the washed shell may be first crushed to prepare a shell granulated product.

In the above step, by first pulverizing the washed shells using a granulator, impurities or organic residues inside the shells can be removed in a later process. It may be performed using a known granulator such as a drum granulator or a compression pelletizer, but is not necessarily limited to the granulator described above.

Next, the shell granulated pulverized product may be immersed in the mixed solution.

In the above step, impurities and organic residues contained in the crushed shell granulated product may be removed by immersing the crushed shell granulated product in the mixed solution. % by weight, 0.01 to 0.1 wt% of persulfate, 1 to 3 wt% of acetic acid, and the remaining amount of purified water, and may be performed by immersing the pulverized shell granulated material in the mixed solution for 10 to 30 minutes.

In addition, as the phosphate compound in the above step, sodium phosphate monobasic (NaH ₂ PO ₄ ), sodium phosphate dibasic (Na ₂ HPO ₄ ), sodium phosphate tritertiary (Na ₃ PO ₄ ), potassium phosphate first (KH _{2 )} PO ₄ ), potassium phosphate dibasic (K ₂ HPO ₄ ), ammonium phosphate monobasic ((NH ₄ )H ₂ PO ₄ ), ammonium phosphate dibasic ((NH ₄ ) ₂ HPO ₄ ), and ammonium tertiary phosphate (( Any one or more selected from the group consisting of NH ₄ ) ₃ PO ₄ ) may be used, and as the persulfate, ammonium persulfate ((NH ₄ ) ₂ S ₂ O ₈ ), sodium persulfate (Na ₂ S ₂ O _{8 )} ) or potassium persulfate (K ₂ O ₈ S ₂ ) Any one or more selected from may be used.

Subsequently, the crushed shell granulated product may be separated from the mixed solution and taken out, and then the shell granulated product may be heated and calcined using a kiln.

In the above step, by heating the separated pulverized shell granulated product using a kiln, the contaminant material adsorbed to the micropores of the pulverized shell granulated product can be removed and activated. After the input, it can be carried out by heating at a temperature of 1,300 to 1,600 ℃ for 50 to 150 minutes.

In addition, in the above step, by going through the firing process as described above, the calcium carbonate constituting the shell may be converted into calcium oxide and carbon dioxide as follows.

Calcium carbonate (CaCO ₃ ) → Calcium oxide (CaO) + carbon dioxide (CO ₂ )

Next, after the second pulverization of the calcined pulverized shell granulated product, impurities may be removed to prepare a pulverized shell granulated product.

In the above step, the calcined shell granulated pulverized product may be pulverized using a ball mill or various known pulverizers. can

In addition, in the above step, impurities such as heavy metals that may remain in the second pulverized shell can be removed by second pulverizing the calcined shell granulated product and then rotating it in a rotary tub installed with a magnet. Specifically, Impurities such as heavy metals that may be included in the second crushed shell may be removed by putting the second pulverized shell into a rotating tub in which a magnet is installed and then rotating it for 20 to 40 minutes at a rotation speed of 500 to 1000 RPM.

Next, it can be inoculated by spraying the lactic acid bacteria culture solution on the pulverized shell particles.

In the above step, it is possible to inoculate the shell fine powder by spraying it at a weight ratio of 1 to 5 parts by weight of the lactic acid bacteria culture solution with respect to 100 parts by weight. , The lactic acid strains include Lactobacillus curvatus ( Lactobacillus curvatus ) , Weissella viridescens , Lactobacillus plantarum ( Lactobacillus plantarum ) and Any one or more known lactic acid strains selected from the group consisting of Leuconostoc lactis may be used.

For example, in the step, the pH of the medium is adjusted to 2.8 to 3.2 using 1.2N HCl to prepare a lactic acid bacteria culture solution from kimchi, and then the lactic acid strain is separated from the kimchi, and the separated lactic acid strain is used in MRS broth (Oxoid). , England), incubated for 20 to 25 hours at 37-39° C., ^{diluted to 1×1.0 8} to 5×1.0 ⁸ CFU/mL, and then centrifuged at 10,000 to 15,000 rpm for 10 to 15 minutes to obtain the supernatant. After separating only (supernatant) and filtering the supernatant with a 0.45 μm syringe filter, sterile distilled water with respect to 100 parts by weight of the filtered supernatant is mixed in a weight ratio of 1,000 to 2,000 parts by weight to dilute lactic acid bacteria A culture solution can be prepared.

Subsequently, the pulverized shellfish inoculated with the lactic acid bacteria culture solution may be fermented.

In the above step, the pulverized shell granules inoculated with the lactic acid bacteria culture medium are maintained at a temperature of 38 to 45° C. and a humidity of 60 to 65%, and then fermented for 5 to 10 days.

Next, the fermented shell powder is washed, dried, and sterilized to prepare shell powder made of calcium powder.

In the above step, the fermented shell fine pulverized product may be washed with purified water and then dried and sterilized, and the configuration of the drying and sterilization process is a known technique for convenience of explanation and the technical idea of the present invention. For clarity, a detailed description thereof will be omitted.

As the polyurethane resin, for example, an acrylic-modified polyurethane resin may be used, and the acrylic-modified polyurethane resin may act as a binder or adhesive for bonding the composition constituting the sheet paper composition.

The acrylic-modified polyurethane may be an acrylic-modified polyurethane prepared by the following manufacturing method.

First, diisocyanate, polyol, and organic solvent may be prepared and mixed to prepare a mixed solution, wherein the mixed solution is diisocyanate 1 mol (mol) and polyol 0.5 to 1.5 mol (mol) is prepared in a ratio of, and the organic solvent may be included in an amount of 60 to 70 wt% (wt%) in the total content of the mixed solution.

The diisocyanate is toluene diisocyanate (TDI), 4,4'-diphenylmethane diisocyanate (4,4'-Diphenylmethane diisocyanate (MDI)), hexamethylene diisocyanate (Hexamethylene diisocyanate (HDI)), Any one or more selected from the group consisting of isophorone diisocyanate (IPDI) and 4,4'-methylenebis (cyclohexyl isocyanate) (4,4'-Methylenebis (cyclohexyl isocyanate) (HMDI)) may be used. .

The polyol may be any one or more selected from polyether polyol and polyester polyol.

The organic solvent may be one or more selected from the group consisting of toluene, methyl ethyl ketone, ethyl acetate, acetone, and dimethylformamide.

Next, by reacting the mixture consisting of the diisocyanate, polyol, and an organic solvent, an isocyanate terminated polyurethane having an isocyanate terminal group can be prepared, and the reaction is performed at a temperature of 83 to 88 ° C. can be done

Next, 0.1 to 0.5 mol (mol) of a monomer (containing hydroxy group) containing a hydroxy group is added to the isocyanate terminated polyurethane having an isocyanate terminal group at a temperature of 83 to 87° C. It can be reacted for 2 to 4 hours to prepare a polyurethane (Vinyl terminated Polyurethane) having a vinyl end group.

The hydroxy group-containing monomer (Monomer (containing hydroxy group)) is 2-hydroxyethyl methacrylate (2-Hydroxyethyl methacrylate), 2-hydroxypropyl methacrylate (2-Hydroxypropyl methacrylate), At least one selected from the group consisting of hydroxyethyl acrylate (2-Hydroxyethyl acrylate) and allyl alcohol may be used.

Then, the acrylic-modified polyurethane can be prepared by reacting while adding a monomer to the vinyl terminated polyurethane having a vinyl end group. The polyurethane and the monomer having a vinyl end group are each poly It may be included in a weight ratio of 70 to 90% by weight of urethane and 10 to 30% by weight of monomer.

In addition, the acrylic-modified polyurethane adhesive can be prepared by reacting for 1 to 3 hours at a temperature of 75 to 80° C. while adding a monomer to the polyurethane having the vinyl end group.

The monomer may be any one or more selected from the group consisting of styrene, methyl methacrylate, acrylonitrile, acrylic acid, and acrylic monomer.

The dispersing agent may be used to prevent precipitation of the sheet composition and to have dispersion properties. For example, the dispersant includes a polyester-polydimethylsiloxane copolymer, dimethylol butanoic acid (DMBA), Any one or more selected from the group consisting of dimethylol propionic acid (DMPA) and methylenediethanolamine may be used.

The body temperature indicator layer 200 may be formed on the sheet support layer 100 to receive body temperature emitted from the skin of a person and display a specific color within a certain temperature range.

The body temperature indicator layer 200 may be configured to change the color of the body temperature indicator layer 200 in a specific region according to a person's body temperature. For example, when the body temperature is normal, the first 1 The body temperature indicator layer 200a is configured to express a specific color, and when the body temperature rises above a specific temperature, the second body temperature indicator layer 200b of the body temperature indicator layer 200 can be configured to express a specific color. have.

In the embodiment of the technical idea of the present invention, the body temperature indicator layer 200 is composed of the first body temperature indicator layer 200a and the second body temperature indicator layer 200b as an example, but the technical idea of the present invention is limited thereto The configuration of the body temperature indicator layer 200 may be variously formed so that various body temperature ranges can be measured depending on the purpose.

The body temperature indicator layer 200 may be manufactured by the following manufacturing method.

In order to prepare the body temperature indicator layer 200, first, a mixed solution in which a water-soluble ethylenically unsaturated monomer, a hydrophilic additive, an endothermic material, a natural plant extract, and a crosslinking agent are mixed in a constant weight ratio is prepared, and then glycerin in the mixed solution And by adding Zion pigment and stirring for 20 to 40 minutes, it is possible to form the body temperature indicator layer 200 in a gel state.

The mixed solution is mixed in a weight ratio of 50 to 80 parts by weight of a water-soluble ethylenically unsaturated monomer, 10 to 20 parts by weight of a hydrophilic additive, 5 to 10 parts by weight of a heat absorbing material, 1 to 3 parts by weight of a natural plant extract, and 2 to 6 parts by weight of a crosslinking agent. The glycerin and the Zion pigment may be included in a weight ratio of 5 to 10 parts by weight of glycerin and 1 to 5 parts by weight of the Zion pigment with respect to 100 parts by weight of the mixed solution.

The Zion pigment is a generic term for pigments whose color is expressed or changed according to a change in temperature, and in the present invention, different Zion pigments are used in the first body temperature indicator layer 200a or the second body temperature indicator layer 200b By using it, it is possible to express a plurality of body temperature ranges. Since the composition of the Zion pigment is a known technology, a detailed description of the Zion pigment will be omitted for convenience of explanation and clarity of the technical idea of the present invention.

As the water-soluble ethylenically unsaturated monomer, conventional water-soluble ethylenically unsaturated monomers used in water absorbent polymers may be used, for example, (meth)acrylic acid, maleic anhydride, crotonic acid, itaconic acid, 2-acryloylethanesulfonic acid, At least one selected from the group consisting of 2-methacryloylethanesulfonic acid and 2-(meth)acryloylpropanesulfonic acid may be used.

The hydrophilic additive may be at least one selected from the group consisting of sodium dodecyl sulfate, phosphate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, and sorbitan monooleate.

The endothermic material is a material causing an endothermic reaction, and for example, any one or more selected from the group consisting of ammonium nitrate, ammonium sulfate, acid ammonium sulfate, ammonium phosphate, ammonium chloride and sodium nitrate may be used.

The natural plant extract may be prepared using natural plants having insecticidal, antibacterial, and anti-parasitic effects against contaminants, mites, pests, etc. A natural plant consisting of paulownia, horsetail, and pine can be used, and the natural plants include ginkgo, cypress, fig, paulownia, horsetail and pine, 1:1:1:1:1:1:1, respectively. It can be blended and mixed in a weight ratio of

The ginkgo tree is denoted by the scientific name Ginkgo biloba L, and is a larch tree belonging to the family Ginkgoaceae, and has been used as a garden tree or roadside tree since ancient times, and its fruit, ginkgo, has been used for food or medicine.

In particular, the leaves of ginkgo biloba have been widely prescribed as a treatment for hypertension, Parkinson's disease and diabetes in oriental medicine since ancient times. It has been found to be effective, and it is widely used as a raw material for cosmetics and functional foods. In addition, in recent years, research on the treatment of antibacterial materials using ginkgo biloba has been actively conducted.

The Albizzia julibrissin Durazzini is distributed in Asia, such as China, Taiwan, Japan, and Korea, and is widely used as a garden tree in Korea. The bark of the Albania tree is listed as a hybrid bark in the Korean Medicine Specifications other than the Korean Pharmacopoeia, and the bark collected in early summer is dried and used. It is cylindrical or semi-cylindrical, and the outer surface is grayish brown or brown, and the inner surface is light yellowish brown or yellowish white. It is odorless, has a mild taste, is astringent, and slightly irritates the tongue. In previous studies, it is known that phytochemicals such as tannins, saponins, and sitosterols are abundantly contained. It is known to have liver, excitatory, diuretic, anthelmintic, antitussive, and analgesic effects.

The fig tree (Ficus carica L) is a deciduous shrub belonging to the family Morus and is native to the Mediterranean coast of Western Asia. The height of the tree is 2~4m, the bark is grayish white, the leaves are alternate phyllotaxis and thick egg-shaped, the surface is rough and there are hairs on the back side. It is known that the latex is effective against athlete's foot, boils and hemorrhoids, the leaves are effective against athlete's foot or neuralgia, and the fruit is effective for lowering blood pressure and constipation.

The paulownia (Paulownia coreana Uyeki) is a deciduous tree belonging to the genus Paulownia in the Hyeonsamaceae family, and is a species endemic to Korea. The height of the paulownia tree is about 15m, and the bark is light brown with dark brown lines running vertically. The bark of the paulownia tree is called Dongpi, and it is known to be effective for bronchopneumonia, bacterial diarrhea, acute enteritis, and acute conjunctivitis.

The horsetail (Equisetum Arvense L) is a perennial herb that grows in mountains and fields across the country. Growing environment: Grow in a sunny or sunny place. The height is 30-40cm, and the genital peduncle appears in early spring and forms a number of sporangia in the shape of an apartment at the end of the stem. The antelope is hollow and grows obliquely, stands upright on the ground, and has vertical corners. The stems are used medicinally. It is also called the philo lobe. It grows on grass and reproduces by extending long stems underground.

The pine tree (picrasma quassioides) contains a very bitter taste of quassin, has a yellow coating on the bark, and grows to about 20 m in height. The leaves are upper-right bifoliate, and the small leaves are broad ovate, the bottom is round, and the tip is sharp. Flowers are yellow-green, male and female, and exudate in the form of bristle in May-June. Fruits are drupes, oval-spherical, and ripen in red around September. Each part, such as leaves, bark, stems, and roots, is used as medicine. It is effective in indigestion, bacterial harri, gastroenteritis, biliary tract infection, and tonsillitis as it has effects of cooling and heat control, dryness, insecticidal, and detoxification. Indigestion, gastritis, and anorexia, etc. have been mainly used as a medicine to treat the stomach.

The natural plant extract can be prepared by fermenting the natural plant and then extracting, for example, the natural plant extract is a microorganism in a natural plant consisting of ginkgo, alpine, fig, paulownia, horsetail, and oxen. It can be prepared by adding and fermenting and then extracting.

In addition, the microorganism to be mixed with the natural plant may be used as the genus Acetobacter sp, and as the microorganism of the genus Acetobacter, Acetobacter aceti may be used.

In addition, the natural plant extract may be prepared by fermenting the natural plant to which the microorganism is added at a temperature of 38 to 42° C. for 3 to 5 days and then extracting it with a solvent.

In addition, as a solvent for extracting the fermented natural plant, water, C1-C6 anhydrous or hydrous lower alcohol, acetone, butylene glycol, ethyl acetate, diethyl acetate, diethyl ether, benzene, chloroform and hexane Any one or more extraction solvents selected from the group may be used.

In addition, the extraction of the fermented natural plant can be extracted using various extraction methods such as hot water extraction, organic solvent extraction, ultrasonic extraction, supercritical extraction, etc. For example, the ultrasonic extraction method is water, C1 as an extraction solvent in the sample ~ C6 anhydrous or hydrous lower alcohol, acetone, butylene glycol, ethyl acetate, diethyl acetate, diethyl ether, benzene, chloroform and any one or more extraction solvent selected from the group consisting of hexane in an amount of 10 to 20 times by volume After addition, it refers to an extraction method performed using an ultrasonic extraction method for 1 to 10 hours, preferably 1 to 4 hours.

In addition, the supercritical extraction method is a fermented natural plant and 500 ~ 700mL of ethanol (99.5%) as an auxiliary solvent put into a supercritical fluid extraction reactor (Natex, Autstria), the temperature in the reactor is 65 ℃, the pressure is 450 bar, S / F ratio (supercritical fluid kg/Feed kg) refers to a method of extraction under the conditions of 35.

Specifically, for example, the natural plant extract may be prepared by the following method.

First, it is washed to remove foreign substances present on the surface of natural plants made up of ginkgo, Albino, fig, paulownia, horsetail, and pine, and the natural plant is washed at a temperature of 30 to 40° C. for 5 to 10 days. After drying for a while, the dried natural plant was pulverized, and 3,500 ml of distilled water per 100 g of the pulverized natural plant was added, and hot water extraction was performed at 150 to 170° C. for 5 hours, followed by filtration to prepare a natural plant hot water extract.

At this time, the natural plants were mixed with ginkgo biloba, sycamore tree, fig tree, paulownia tree, horsetail and pine tree in a weight ratio of 1:1:1:1:1:1, respectively.

The filtered natural plant hot water extract was concentrated under reduced pressure at 60 to 65° C., adjusted to a final concentration of 450 ml, and filtered to prepare a natural plant extract.

The natural plant extract was added to the culture medium of Acetobacter aceti in an amount of 10 g/L.

Here, dextrose as a carbon source and dipotassium phosphate as a pH adjuster were added.

At this time, Acetobacter aceti was used as the strain used, and 50,000 cfu/L per culture was added.

The culture was cultured using a fermenter for 10 days, maintained at 35°C, pH 5-7, and after culturing, the culture medium was centrifuged to remove the first culture, followed by final filtration using a filter.

The filtrate obtained in this way was aged again for 10 days in a low-temperature warehouse at 4° C., and then the liquid was filtered again using a filter to prepare a natural plant extract.

The cross-linking agent is added to maintain a stable gel strength in a swollen state by absorbing moisture and absorption rate. For example, the cross-linking agent includes ethyleneoxy (meth) acrylate, polyethyleneoxy (meth) acrylate, Any one or more selected from the group consisting of propyleneoxy (meth)acrylate, glycerin diacrylate, glycerin triacrylate, trimethylol triacrylate, and triallylamine may be used.

The adhesive layer 300 is formed under the sheet backing layer 100 to be adhered to a target surface (eg, skin), and the adhesive layer 300 is a point on the bottom of the sheet backing layer 100 . It may be formed by applying a wear composition.

The adhesive composition comprises 80 to 120 parts by weight of a polyurethane acrylate-based oligomer, 10 to 20 parts by weight of a solvent, 20 to 30 parts by weight of a bisphenol A epoxy resin, and 5 to 10 parts by weight of polyvinyl alcohol. , can be prepared by mixing 1 to 2 parts by weight of natural rubber and 0.1 to 1.5 parts by weight of antioxidant.

The polyurethane acrylate-based oligomer is a compound having a weight average molecular weight (Mw) of 3,000 to 30,000, and may be formed by reacting polycarbonate and polyester diol with isocyanate and acrylate.

The polyurethane acrylate oligomer includes a urethane bond as a repeating unit, and typically exhibits flexible physical properties. The polyurethane acrylate oligomer has various types, and depending on the type of isocyanate used, aliphatic urethane acrylate and aromatic urethane acrylic divided by rate.

The aliphatic urethane acrylate oligomer is a non-yellowing type, usually having 2 to 20 functional groups, and the aromatic urethane acrylate oligomer is a yellowing type, and has fast reactivity.

In addition, the polyurethane acrylate oligomer may have 3 to 15 functional groups, and the number of functional groups may impart surface hardness and adhesion by interaction with a solvent and a photocuring agent.

Examples of the functional group include urethane acrylate, epoxy acrylate, carboxylic acid, carboxylic anhydride, an acrylate-based functional group having a C=C double bond (eg, methacrylate, acrylate, etc.), SH Groups, alcohols, esters, ethers, triethylene glycolate, chelating agents (eg, aminotriethanolate, aminodiethanolate, acetylacetonate, ethylacetoacetate, lactate, etc.), amine groups, amides , oxazoline and carbamate may be used alone or by selecting two or more.

The solvent may be used to control viscosity and fluidity, and as the solvent, an ether-based solvent, an aromatic solvent, an acetate-based solvent, a ketone-based solvent, an alcohol-based solvent, or a solvent in which they are mixed may be used.

For example, as the ether solvent, propylene glycol monopropyl ether, propylene glycol monomethyl ether, ethylene glycol monoethyl ether, ethylene glycol monopropyl ether, ethylene glycol monobutyl ether, diethylene glycol monomethyl ether, diethyl Glycol monoethyl ether, diethyl glycol monopropyl ether, diethyl glycol monobutyl ether, diethylene glycol-2-ethylhexyl ether, etc. can be used alone or in combination.

Toluene and xylene may be used alone or in combination as the aromatic solvent, and butyl acetate, ethyl acetate, etc. may be used alone or in combination as the acetate-based solvent. The ketone-based solvent may be used alone or in combination with acetone, methyl ethyl ketone, methyl isobutyl ketone, and the like.

As the alcohol-based solvent, diacetone alcohol (DAA), n-butanol, methanol, ethanol, isopropyl alcohol, and the like may be used alone or in combination.

The bisphenol A type epoxy resin has excellent adhesion, and the bisphenol A type epoxy resin may be a mixture of a bisphenol A type epoxy resin having an epoxy equivalent of 186 to 190 and a bisphenol A type epoxy resin having an epoxy equivalent of 600 to 700. .

The polyvinyl alcohol has characteristics such as excellent linearity, flat zig-zag conformation, high crystallinity, excellent alkali resistance withstanding even at pH 13.5 or higher, and excellent adhesion.

The application of the polyvinyl alcohol is expanding due to the excellent physical properties and various application ranges as described above. In particular, many studies have been made on the production of high-strength and high-modulus gels using polyvinyl alcohol and the production of high-performance polyvinyl alcohol fibers.

As an example, polyvinyl alcohol is applicable to membrane separation technology using a polymer film. Polymer films are being used in a wide range of fields such as chemical industry, biotechnology, resources, energy, and environment. In particular, the pervaporation method capable of separating a liquid organic mixture or an organic aqueous solution has many advantages, such as energy saving and device miniaturization, compared to the traditional distillation method, and is widely used in the production of anhydrous alcohol and separation of organic mixtures. Therefore, it can be said that polyvinyl alcohol has high utility in the field of polymer films.

In addition, polyvinyl alcohol can be applied to the technology of manufacturing microfibers by electrospinning technology. In the method of manufacturing microfibers by electrospinning technology, a high voltage is applied to a polymer resin solution to induce the formation of a liquid jet in the solution discharged from the spinneret, and at this time, the electric repulsive force is generated during the volatilization of the solvent. It is characterized in that fibers having a fine thickness are obtained by continuous stretching.

In particular, when the electrospinning technology is used, the fiber yarns are accumulated on the collector in the form of a web, which is a three-dimensional network structure. do. Therefore, polyvinyl alcohol can be applied in a wide range of fields such as microfibers, industrial materials including filters, photochemical sensor materials, biomedical materials, and cosmetic materials.

The natural rubber (Natural rubber: NR) is a rubber using a raw material produced from a plant, and mainly uses a raw material produced from a rubber tree. The natural rubber may be a general natural rubber or a modified natural rubber.

Any general natural rubber may be used as long as it is known as a natural rubber, and the country of origin is not limited. In addition, although general natural rubber contains cis-1,4-polyisoprene as a main chain, it may contain trans-1,4-polyisoprene according to required properties.

Accordingly, the natural rubber includes trans-1,4-polyisoprene as a main chain, for example, Valata, a type of rubber of the Sapotaceae family from South America, in addition to a natural rubber containing cis-1,4-polyisoprene as a main chain. It may also contain natural rubber that

The modified natural rubber means that the general natural rubber is modified or refined. For example, the modified natural rubber may include an epoxidized natural rubber, a deproteinized natural rubber, and a hydrogenated natural rubber.

As the antioxidant, tetrakis [methylene-3- (dodecylthio) propionate] methane may be used, and the antioxidant is included in the adhesive composition and used to block UV rays and inhibit radical decomposition of the cured coating film. can

In the above, a preferred embodiment of the present invention has been described, but those of ordinary skill in the art to which the present invention pertains will understand that the present invention may be embodied in other specific forms without changing the technical spirit or essential features thereof. will be able Therefore, it should be understood that the embodiment described above is illustrative in all respects and not restrictive.

10; sticker type thermometer
100; sheet layer
200; body temperature indicator
200a; first body temperature indicator layer
200b; second body temperature indicator layer
300; adhesive layer
400; heteromorphic strata

Claims (4)

sheet backing layer;
a body temperature indicator layer formed on the sheet support layer;
an adhesive layer formed under the sheet support layer and adhered thereto; and
and a release paper layer positioned under the adhesive layer to protect the adhesive layer,
The body temperature indicator layer includes a first body temperature indicator layer and a second body temperature indicator layer, and the first body temperature indicator layer and the second body temperature indicator layer receive body temperature emitted from the skin of a person and receive a specific temperature within a certain temperature range. A sticker-type thermometer for measuring fever, characterized in that it is configured to indicate color.
The method of claim 1,
The sheet paper layer is formed by mixing the sheet paper composition and then drying, the sheet paper composition is 1 to 5 parts by weight of copper nanoparticles, 1 to 3 parts by weight of gelite, 0.1 to 1 parts by weight of shell powder, 100 to 200 parts by weight of polyurethane resin A sticker type thermometer for measuring fever, characterized in that it is included in a weight ratio of 1 to 3 parts by weight and 1 to 3 parts by weight of the dispersant.
3. The method of claim 2,
The body temperature indicator layer is first prepared by preparing a mixed solution in which a water-soluble ethylenically unsaturated monomer, a hydrophilic additive, an endothermic material, a natural plant extract, and a crosslinking agent are mixed in a constant weight ratio, and then glycerin and Zion pigment are added to the mixed solution, It is prepared through a process of stirring for 20 to 40 minutes,
The mixed solution is mixed in a weight ratio of 50 to 80 parts by weight of a water-soluble ethylenically unsaturated monomer, 10 to 20 parts by weight of a hydrophilic additive, 5 to 10 parts by weight of a heat absorbing material, 1 to 3 parts by weight of a natural plant extract, and 2 to 6 parts by weight of a crosslinking agent. A sticker-type thermometer for measuring fever, wherein the glycerin and the Zion pigment are included in a weight ratio of 5 to 10 parts by weight of glycerin and 1 to 5 parts by weight of the Zion pigment with respect to 100 parts by weight of the mixed solution.
4. The method of claim 3,
The adhesive layer is formed by applying an adhesive composition to the lower portion of the sheet paper layer, wherein the adhesive composition includes 80 to 120 parts by weight of a polyurethane acrylate-based oligomer, 10 to 20 parts by weight of a solvent, and a bisphenol A type epoxy resin. A sticker-type thermometer for measuring fever, characterized in that it contains 20 to 30 parts by weight, 5 to 10 parts by weight of polyvinyl alcohol, 1 to 2 parts by weight of natural rubber, and 0.1 to 1.5 parts by weight of antioxidant.

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