KR20220004011A - 도세탁셀 및 cyp3a 억제제를 사용하는 고형 종양의 조합 치료 - Google Patents

도세탁셀 및 cyp3a 억제제를 사용하는 고형 종양의 조합 치료 Download PDF

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Publication number
KR20220004011A
KR20220004011A KR1020217022969A KR20217022969A KR20220004011A KR 20220004011 A KR20220004011 A KR 20220004011A KR 1020217022969 A KR1020217022969 A KR 1020217022969A KR 20217022969 A KR20217022969 A KR 20217022969A KR 20220004011 A KR20220004011 A KR 20220004011A
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South Korea
Prior art keywords
docetaxel
cyp3a
cyp3a inhibitor
cancer
combination
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Ceased
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KR1020217022969A
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English (en)
Korean (ko)
Inventor
제이콥 헨드릭 베이젠
요하네스 헨리쿠스 마티아스 셸렌스
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모드라 파마슈티컬스 비.브이.
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Application filed by 모드라 파마슈티컬스 비.브이. filed Critical 모드라 파마슈티컬스 비.브이.
Publication of KR20220004011A publication Critical patent/KR20220004011A/ko
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020217022969A 2018-12-21 2019-12-18 도세탁셀 및 cyp3a 억제제를 사용하는 고형 종양의 조합 치료 Ceased KR20220004011A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18215488.0 2018-12-21
EP18215488 2018-12-21
PCT/EP2019/086125 WO2020127607A1 (en) 2018-12-21 2019-12-18 Combination treatment for solid tumors using docetaxel and a cyp3a inhibitor

Publications (1)

Publication Number Publication Date
KR20220004011A true KR20220004011A (ko) 2022-01-11

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KR1020217022969A Ceased KR20220004011A (ko) 2018-12-21 2019-12-18 도세탁셀 및 cyp3a 억제제를 사용하는 고형 종양의 조합 치료

Country Status (13)

Country Link
US (1) US20220071944A1 (enExample)
EP (1) EP3897611A1 (enExample)
JP (3) JP2022514960A (enExample)
KR (1) KR20220004011A (enExample)
CN (1) CN113473982A (enExample)
AU (2) AU2019410062A1 (enExample)
BR (1) BR112021012266A2 (enExample)
CA (1) CA3124319C (enExample)
CL (1) CL2021001635A1 (enExample)
IL (1) IL284225A (enExample)
MX (1) MX2021007480A (enExample)
PE (1) PE20220129A1 (enExample)
WO (1) WO2020127607A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113543781A (zh) * 2018-12-21 2021-10-22 莫德拉药物股份有限责任公司 通过控制峰值血浆水平使用多西他赛的癌症治疗
GB202201935D0 (en) 2022-02-14 2022-03-30 Modra Pharmaceuticals B V Methods and compositions for treating cancer in taxane-resistant patients
CN116270617B (zh) * 2023-03-29 2024-01-26 济宁医学院附属医院 Arp2/3复合物抑制剂CK-666和多西他赛组合用于癌症治疗的制药用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008291930B2 (en) * 2007-08-24 2014-04-17 Slotervaart Participaties Bv Compositions for the treatment of neoplastic diseases
GB0716591D0 (en) * 2007-08-24 2007-10-03 Vereniging Het Nl Kanker I Composition
US9089544B2 (en) * 2007-08-24 2015-07-28 Slotervaart Participaties Bv Composition
EP2328555A2 (en) 2008-08-22 2011-06-08 Slotervaart Participaties BV Compositions for the treatment of neoplastic diseases
CN113543781A (zh) * 2018-12-21 2021-10-22 莫德拉药物股份有限责任公司 通过控制峰值血浆水平使用多西他赛的癌症治疗

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Publication number Publication date
AU2023204693A1 (en) 2023-08-10
CA3124319A1 (en) 2020-06-25
CA3124319C (en) 2023-07-04
IL284225A (en) 2021-08-31
WO2020127607A1 (en) 2020-06-25
JP2025094186A (ja) 2025-06-24
BR112021012266A2 (pt) 2021-08-31
EP3897611A1 (en) 2021-10-27
JP2023102786A (ja) 2023-07-25
PE20220129A1 (es) 2022-01-27
US20220071944A1 (en) 2022-03-10
CL2021001635A1 (es) 2022-04-22
CN113473982A (zh) 2021-10-01
MX2021007480A (es) 2021-10-13
AU2019410062A1 (en) 2021-08-12
JP2022514960A (ja) 2022-02-16

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