KR20210139271A - Crispr/cas 융합 단백질 및 시스템 - Google Patents
Crispr/cas 융합 단백질 및 시스템 Download PDFInfo
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- KR20210139271A KR20210139271A KR1020217029732A KR20217029732A KR20210139271A KR 20210139271 A KR20210139271 A KR 20210139271A KR 1020217029732 A KR1020217029732 A KR 1020217029732A KR 20217029732 A KR20217029732 A KR 20217029732A KR 20210139271 A KR20210139271 A KR 20210139271A
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| EP3204496A1 (en) | 2014-10-10 | 2017-08-16 | Editas Medicine, Inc. | Compositions and methods for promoting homology directed repair |
| CA3129835A1 (en) | 2019-02-15 | 2020-08-20 | Sigma-Aldrich Co. Llc | Crispr/cas fusion proteins and systems |
| JP2024533311A (ja) * | 2021-09-08 | 2024-09-12 | フラッグシップ パイオニアリング イノベーションズ シックス，エルエルシー | ゲノムを調節するための方法及び組成物 |
| CN116063546B (zh) * | 2021-10-29 | 2026-01-16 | 中科辅酶医科技(深圳)有限公司 | 一种基于共振能量转移的全遗传编码nad+蛋白探针及其制备方法和应用 |
| US20230265405A1 (en) * | 2022-02-22 | 2023-08-24 | Massachusetts Institute Of Technology | Engineered nucleases and methods of use thereof |
| JP2025510574A (ja) * | 2022-03-08 | 2025-04-15 | ウェイク・フォレスト・ユニバーシティ・ヘルス・サイエンシーズ | 真核生物遺伝子編集のための組成物、システムおよび方法 |
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| EP3241902B1 (en) | 2012-05-25 | 2018-02-28 | The Regents of The University of California | Methods and compositions for rna-directed target dna modification and for rna-directed modulation of transcription |
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| WO2016054326A1 (en) | 2014-10-01 | 2016-04-07 | The General Hospital Corporation | Methods for increasing efficiency of nuclease-induced homology-directed repair |
| WO2016210271A1 (en) | 2015-06-24 | 2016-12-29 | Sigma-Aldrich Co. Llc | Cell cycle dependent genome regulation and modification |
| JP6867689B2 (ja) * | 2016-01-29 | 2021-05-12 | 国立大学法人東京工業大学 | Ｃａｓ９−ｇＲＮＡ複合体の細胞核内への導入方法、及び細胞内における標的遺伝子の改変方法 |
| WO2017173004A1 (en) * | 2016-03-30 | 2017-10-05 | Mikuni Takayasu | A method for in vivo precise genome editing |
| WO2017180694A1 (en) | 2016-04-13 | 2017-10-19 | Editas Medicine, Inc. | Cas9 fusion molecules gene editing systems, and methods of use thereof |
| CN107579793A (zh) * | 2016-07-04 | 2018-01-12 | 中兴通讯股份有限公司 | 一种通信网络设备间时间同步的优化方法、装置及设备 |
| KR102547316B1 (ko) * | 2016-08-03 | 2023-06-23 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 아데노신 핵염기 편집제 및 그의 용도 |
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| JP7182545B2 (ja) | 2016-12-14 | 2022-12-02 | ヴァーヘニンゲン ユニヴェルシテット | 熱安定性ｃａｓ９ヌクレアーゼ |
| EP3592853A1 (en) | 2017-03-09 | 2020-01-15 | President and Fellows of Harvard College | Suppression of pain by gene editing |
| GB201710973D0 (en) | 2017-07-07 | 2017-08-23 | Avacta Life Sciences Ltd | Scaffold proteins |
| KR20200036912A (ko) | 2017-07-31 | 2020-04-07 | 리플렉션 바이오테크놀러지스 리미티드 | 안과 질환을 위한 세포 모델 및 치료요법 |
| US11071791B2 (en) * | 2018-01-26 | 2021-07-27 | Wisconsin Alumni Research Foundation | Vector for gene silencing and replacement and methods of use thereof |
| CN111902536B (zh) | 2018-02-15 | 2024-07-30 | 西格马-奥尔德里奇有限责任公司 | 用于真核基因组修饰的改造的cas9系统 |
| PL3765615T3 (pl) * | 2018-03-14 | 2023-11-13 | Arbor Biotechnologies, Inc. | Nowe enzymy i układy crispr ukierunkowane na dna |
| CA3129835A1 (en) | 2019-02-15 | 2020-08-20 | Sigma-Aldrich Co. Llc | Crispr/cas fusion proteins and systems |
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