KR20210067676A - Optical measuring sensor for protein detection - Google Patents

Optical measuring sensor for protein detection Download PDF

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KR20210067676A
KR20210067676A KR1020190157529A KR20190157529A KR20210067676A KR 20210067676 A KR20210067676 A KR 20210067676A KR 1020190157529 A KR1020190157529 A KR 1020190157529A KR 20190157529 A KR20190157529 A KR 20190157529A KR 20210067676 A KR20210067676 A KR 20210067676A
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infrared
blood
receiver
blaster
measuring sensor
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양태양
최이진
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주식회사 지니컵
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Priority to PCT/KR2020/014067 priority patent/WO2021107398A1/en
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/22—Haematology

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Abstract

The present invention relates to an optical protein measurement sensor, and provides an optical ferritin measurement sensor comprising: a body; a main part which is recessed from one side of the upper surface of the body and in which blood is placed; an infrared blaster which is buried in one side, corresponding to the main part, of one side of the body, and which has an upper part exposed to the outside so as to emit infrared rays upward; a receiver which is buried in the side of the infrared blaster of one side of the body, and which has an upper part exposed to the outside so as to receive the infrared rays emitted from the infrared blaster; and an analysis unit which is electrically connected to the receiver, and which analyzes the amount of ferritin in the blood on the basis of the amount of received infrared rays. The simple structure of the present invention allows the sensor to obtain an accurate measurement of blood's iron content and can be reused.

Description

광학식 프로틴 측정 센서{Optical measuring sensor for protein detection}Optical measuring sensor for protein detection

본 발명은 광학식 프로틴 측정 센서에 관한 것으로서, 보다 상세하게는 구조가 간단하면서도 혈액 내 철분을 정확하게 측정할 수 있으며, 재사용이 가능한 광학식 프로틴 측정 센서에 관한 것이다.The present invention relates to an optical protein measuring sensor, and more particularly, to an optical protein measuring sensor that has a simple structure, can accurately measure iron in blood, and can be reused.

사람은 생리를 할 때 상당량의 철분을 잃으며, 철분이 부족하면 빈혈등의 증상을 보일 수 있다. 이러한 철분을 보충하기 위해 여성들은 철분 보충제를 복용하게 되는데, 철분을 과다하게 복용하는 경우 과다증이 발생할 수 있으며, 이러한 철분 과다증으로 인해 오히려 생리통을 악화시킬 수 있다.Humans lose a significant amount of iron during menstruation, and iron deficiency can cause symptoms such as anemia. In order to supplement this iron, women take iron supplements. If you take too much iron, overdose may occur, and this excess iron may make menstrual pain worse.

이에 일부 여성들은 시중에서 판매되는 철분센서를 구입하여 체내 철분을 측정하고, 측정된 철분량에 따라 적절하게 철분 보충제를 조절하고 있다.Accordingly, some women purchase a commercially available iron sensor, measure the iron in their body, and adjust iron supplements appropriately according to the measured amount of iron.

현재, 시중에 판매되고 있는 철분 센서는 화학적 반응을 이용한 페이퍼 기반의 시험지로서, 일회성 아날로그 형태이다.Currently, the iron sensor sold on the market is a paper-based test strip using a chemical reaction, in the form of a one-time analog.

그러나, 최근에는 전자제품이 급격하게 발전함에 따라 타 기기들과 정보를 쉽게 교류할 수 있는 IoT 기반의 제품들이 대거 출시되고 있는 바 위에서 측정한 철분 수치를 IoT기반의 제품에 적용하기 위해 재사용이 가능한 철분 측정 전자 센서가 요구되고 있다.However, in recent years, with the rapid development of electronic products, IoT-based products that can easily exchange information with other devices are being released. An iron measuring electronic sensor is in demand.

본 발명은 상기와 같은 문제점을 해결하기 위해 안출된 것으로서, 본 발명의 목적은 구조가 간단하면서도 혈액 내 철분을 정확하게 측정할 수 있으며, 재사용이 가능한 광학식 프로틴 측정 센서를 제공함에 있다.The present invention has been devised to solve the above problems, and an object of the present invention is to provide an optical protein measuring sensor that can accurately measure iron in blood while having a simple structure, and can be reused.

상기와 같은 목적을 달성하기 위한 본 발명의 일측면에 따르면, 본체와, 상기 본체 상면 일측으로부터 함몰형성되고, 혈액이 안착되는 메인부와, 상기 본체의 일측 중 상기 메인부와 대응되는 일측에 매립되되, 상부가 외부로 노출되어 상방으로 적외선을 조사하는 적외선 블래스터와, 상기 본체의 일측 중 상기 적외선 블래스터 측부에 매립되되, 상부가 외부로 노출되어 상기 적외선 블래스터로부터 조사된 적외선을 수신하는 리시버 및 상기 리시버와 전기적으로 연결되고, 수신된 적외선량을 기초하여 상기 혈액에 페로틴 양을 분석하는 분석부를 포함하는 것을 특징으로 하는 광학식 페로틴 측정센서를 제공한다.According to one aspect of the present invention for achieving the above object, a main body, a main part recessed from one side of the upper surface of the main body, and on which blood is seated, and one side of the body embedded in one side corresponding to the main part Doedoe, an infrared blaster having an upper portion exposed to the outside to irradiate infrared rays upward, a receiver embedded in the infrared blaster side of one side of the body, the upper portion being exposed to the outside to receive infrared ray irradiated from the infrared blaster, and the above It provides an optical ferrotine measuring sensor electrically connected to the receiver and comprising an analysis unit for analyzing the amount of ferrotin in the blood based on the received infrared amount.

그리고, 상기 적외선 블래스터 및 상기 리시버 상부에 설치된 680nm의 필터부를 더 포함하는 것이 바람직하다.And, it is preferable to further include a 680nm filter unit installed on the infrared blaster and the receiver.

상기와 같은 본 발명에 따르면, 구조가 간단하면서도 혈액 내 철분을 정확하게 측정할 수 있으며, 재사용이 가능한 효과가 있다.According to the present invention as described above, although the structure is simple, it is possible to accurately measure iron in the blood, and there is an effect that can be reused.

도1은 본 발명의 일실시예에 따른 광학식 프로틴 측정 센서를 개략적으로 도시한 도면,
도2는 본 발명의 일실시예에 따른 광학식 프로틴 측정 센서의 동작을 도시한 도면.1 is a view schematically showing an optical protein measuring sensor according to an embodiment of the present invention;
Figure 2 is a view showing the operation of the optical protein measuring sensor according to an embodiment of the present invention.

이하에서는 첨부된 도면을 참조하여 본 발명의 바람직한 일 실시예를 상세하게 설명하기로 한다.Hereinafter, a preferred embodiment of the present invention will be described in detail with reference to the accompanying drawings.

도1은 본 발명의 일실시예에 따른 광학식 프로틴 측정 센서를 개략적으로 도시한 도면이다.1 is a view schematically showing an optical protein measuring sensor according to an embodiment of the present invention.

도1에서 보는 바와 같이 본 발명의 일실시예에 따른 광학식 프로틴 측정 센서(1)는 본체(10)와, 메인부(20)와, 적외선 블래스터(30)와, 리시버(40) 및 분석부(50)를 포함하여 구성된다.As shown in FIG. 1, the optical protein measurement sensor 1 according to an embodiment of the present invention has a main body 10, a main unit 20, an infrared blaster 30, a receiver 40, and an analysis unit ( 50) is included.

본체(10)는 대략 플레이트 형상으로 형성되고, 설치대상영역에 안착되어 혈액 측정이 안정적으로 이루어질 수 있도록 후술하는 구성을 지지하는 역할을 한다.The main body 10 is formed in a substantially plate shape, and serves to support a configuration to be described later so that blood measurement can be stably performed by being seated in the installation target area.

메인부(20)는 본체(10)의 상면 일측으로부터 함몰형성되고, 혈액이 안착되는 안착영역(21)을 제공하는 역할을 한다.The main part 20 is recessed from one side of the upper surface of the main body 10 and serves to provide a seating area 21 in which blood is seated.

적외선 블래스터(30)는 메인부(20)가 형성된 본체(10)의 일측에 매립되되, 상부가 외부로 노출되게 설치되며, 상방으로 적외선을 조사하는 역할을 한다.The infrared blaster 30 is embedded in one side of the main body 10 in which the main part 20 is formed, the upper part is installed to be exposed to the outside, and serves to irradiate infrared rays upward.

리시버(40)는 메인부(20)가 형성된 본체(10)의 일측 중 적외선 블래스터(30) 측부에 매립되되, 이 또한 상부가 외부로 노출되게 설치되며, 적외선 블래스터(30)로부터 조사되어 혈액에 반사된 적외선을 수신하는 역할을 한다.The receiver 40 is embedded in the infrared blaster 30 side of one side of the main body 10 on which the main part 20 is formed, which is also installed so that the upper part is exposed to the outside, and is irradiated from the infrared blaster 30 to the blood. It serves to receive the reflected infrared rays.

이러한 적외선 블래스터(30) 및 리시버(40)는 당해 기술분야에서 통상의 지식을 갖는 자에게는 상용적으로 공급되는 것을 구입하여 사용할 수 있을 정도로 공지된 것임이 자명한 것으로서 구체적인 구성설명은 생략하도록 한다.The infrared blaster 30 and the receiver 40 are known enough to be used by those of ordinary skill in the art to be able to purchase and use those that are commercially supplied, and detailed configuration descriptions will be omitted.

분석부(50)는 리시버(40)와 전기적으로 연결되고, 리시버(40)에 수신된 적외선량에 기초하여 혈액에 포함된 페로틴 양을 분석하는 역할을 한다.The analyzer 50 is electrically connected to the receiver 40 and serves to analyze the amount of ferrotin contained in the blood based on the amount of infrared rays received by the receiver 40 .

한편, 본 실시예에 따른 분석부(50)는 혈액, 즉 생리혈로부터 철분을 직접 측정하는 방식이 아닌 저장철의 지표인 페로틴이라는 혈내 단백질 함량을 측정하고, 페로틴 수치에 따라 혈액 내 철분을 검출하는 구조가 사용된다.On the other hand, the analysis unit 50 according to the present embodiment measures the blood protein content called ferrotin, which is an indicator of stored iron, rather than a method of directly measuring iron from blood, that is, menstrual blood, and measures iron in the blood according to the ferrotin level The detection structure is used.

그리고, 본 실시예에서는 블래스터 및 리시버(40) 상부에 680nm의 필터부(60)가 설치되는데, 이는 블래스터로부터 조사되는 적외선 및 리시버(40)로 수신되는 적외선 중 680nm의 주파수를 갖는 적외선을 필터링함으로써 보다 정확한 측정이 이루어질 수 있도록 하기 위함이다.And, in the present embodiment, a filter unit 60 of 680 nm is installed on the blaster and the receiver 40, which filters infrared rays having a frequency of 680 nm among infrared rays irradiated from the blaster and infrared rays received by the receiver 40. This is to enable more accurate measurement.

도2는 본 발명의 일실시예에 따른 광학식 프로틴 측정 센서의 동작을 도시한 도면이다.Figure 2 is a view showing the operation of the optical protein measuring sensor according to an embodiment of the present invention.

이와 같은 구조를 갖는 본 발명의 일실시예에 따른 광학식 프로틴 측정 센서(1)의 동작을 첨부된 도2를 참조하여 설명하면 다음과 같다.The operation of the optical protein measurement sensor 1 according to an embodiment of the present invention having such a structure will be described with reference to FIG. 2 attached thereto.

먼저, 메인부(20) 상면에 측정하고자 하는 혈액을 안착시킨다.First, the blood to be measured is seated on the upper surface of the main unit 20 .

이후, 적외선 블래스터(30)로부터 상방으로 적외선이 조사되고, 적외선 블러스터 상부에 위치한 필터부(60)를 통과한 적외선이 혈액을 통과한 후 혈액 표면에 반사된다.Thereafter, infrared rays are irradiated upward from the infrared blaster 30 , and the infrared rays passing through the filter unit 60 located above the infrared blaster pass through the blood and are reflected on the blood surface.

이와 같이 혈액을 통과하면서 적외선 일부가 혈액에 흡수되며, 혈액 표면에 반사된 적외선은 리시버(40) 상부에 위치한 필터부(60)를 통과한 후 리시버(40)에 수신된다.In this way, some infrared rays are absorbed into the blood while passing through the blood, and the infrared rays reflected on the blood surface pass through the filter unit 60 located above the receiver 40 and are then received by the receiver 40 .

그리고, 분석부(50)에서는 리시버(40)에 수신된 적외선량에 기초하여 혈액 내 프로틴 수치를 검출하고, 검출된 프로틴 수치에 따라 혈액 내 철분량을 분석하여 이를 사용자에게 안내한다.And, the analysis unit 50 detects the protein level in the blood based on the amount of infrared light received by the receiver 40, and analyzes the amount of iron in the blood according to the detected protein level, and guides it to the user.

비록 본 발명이 상기 언급된 바람직한 실시예와 관련하여 설명되어졌지만, 발명의 요지와 범위로부터 벗어남이 없이 다양한 수정이나 변형을 하는 것이 가능하다. 따라서 첨부된 특허청구의 범위는 본 발명의 요지에서 속하는 이러한 수정이나 변형을 포함할 것이다.Although the present invention has been described with reference to the above-mentioned preferred embodiments, various modifications and variations are possible without departing from the spirit and scope of the invention. Accordingly, the appended claims are intended to cover such modifications and variations as fall within the scope of the present invention.

10 : 본체 20 : 메인부
21 : 안착영역 30 : 적외선 블래스터
40 : 리시버 50 : 분석부
60 : 필터부10: body 20: main part
21: seating area 30: infrared blaster
40: receiver 50: analysis unit
60: filter unit

Claims (2)

본체와;
상기 본체 상면 일측으로부터 함몰형성되고, 혈액이 안착되는 메인부와;
상기 본체의 일측 중 상기 메인부와 대응되는 일측에 매립되되, 상부가 외부로 노출되어 상방으로 적외선을 조사하는 적외선 블래스터와;
상기 본체의 일측 중 상기 적외선 블래스터 측부에 매립되되, 상부가 외부로 노출되어 상기 적외선 블래스터로부터 조사된 적외선을 수신하는 리시버; 및
상기 리시버와 전기적으로 연결되고, 수신된 적외선량을 기초하여 상기 혈액에 페로틴 양을 분석하는 분석부를 포함하는 것을 특징으로 하는 광학식 페로틴 측정센서.
a body;
a main part which is recessed from one side of the upper surface of the main body and on which blood is seated;
an infrared blaster embedded in one side of one side of the main body corresponding to the main part, the upper part being exposed to the outside, and irradiating infrared rays upward;
a receiver embedded in the infrared blaster side of one side of the body, the upper portion being exposed to the outside to receive the infrared ray irradiated from the infrared blaster; and
An optical ferrotin measuring sensor electrically connected to the receiver and comprising an analyzer for analyzing the amount of ferrotin in the blood based on the received infrared amount.
 제1항에 있어서,
상기 적외선 블래스터 및 상기 리시버 상부에 설치된 680nm의 필터부를 더 포함하는 것을 특징으로 하는 광학식 페로틴 측정센서.
According to claim 1,
Optical ferrotine measuring sensor, characterized in that it further comprises a filter unit of 680nm installed on the infrared blaster and the receiver.
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