KR20210052797A - Hydrogel sheet containing alginate granules and manufacturing method thereof - Google Patents

Abstract

The present invention relates to a hydrogel sheet containing a hydrogel and alginate grains contained in the hydrogel, and to a manufacturing method thereof. The hydrogel sheet has high strength and excellent adhesion by containing the alginate grains inside the hydrogel.

Description

Hydrogel sheet containing alginate grains and its manufacturing method {HYDROGEL SHEET CONTAINING ALGINATE GRANULES AND MANUFACTURING METHOD THEREOF}

The present specification relates to a hydrogel sheet comprising alginate grains.

Recently, a mask pack using a hydrogel sheet is gaining popularity. Hydrogel is a material having a three-dimensional hydrophilic polymer network structure using water as a dispersion medium, and it contains a large amount of moisture and exhibits the same flexibility as a natural tissue.

Existing hydrogel sheets are manufactured by heating and cooling after mixing natural gelling agents, polysaccharides, and various cosmetic compositions. Such a hydrogel sheet can contain a large amount of moisture, so it has the advantage of excellent cooling feeling, moisturizing power, and adhesion, but its aesthetics are poor due to its uniform design and color.

A hydrogel sheet including beads may be manufactured to compensate for the disadvantages of poor aesthetics, but there is a problem that the beads may be broken when mixed, and uniform coating by beads in the coating process is difficult.

In addition, there have been attempts to increase the strength of the hydrogel sheet through a crosslinking roll of alginate and calcium ions, but as the strength increases, the adhesion of the hydrogel sheet decreases, and there is a problem in that effective ingredients are not effectively delivered.

Accordingly, it is necessary to develop a hydrogel sheet having high strength and excellent adhesion and aesthetics.

Korean Patent Application Publication No. 10-2019-0058919

In one aspect, an object of the present invention is to provide a hydrogel sheet having high strength and excellent adhesion, including alginate grains.

In one aspect, the present invention comprises a first agent comprising a hydrophilic polymer and a calcium salt; And it provides a composition for gelation comprising a second agent containing an alkali metal salt of alginic acid.

In an exemplary embodiment, the hydrophilic polymer is galactomannan, glucomannan, guar gum, locust bean gum, pluronic, agar, It may include at least one selected from the group consisting of carrageenan, xanthan gum, and gellan gum.

In an exemplary embodiment, the calcium salt may include at least one selected from the group consisting of calcium hydroxide, calcium carbonate, calcium chloride, and calcium lactate.

In an exemplary embodiment, the alkali metal salt of alginic acid may include at least one selected from the group consisting of sodium alginate and potassium alginate.

In one aspect, the present invention provides a hydrogel sheet including a hydrogel and alginate grains contained within the hydrogel.

In one exemplary embodiment, the hydrogel is galactomannan, glucomannan, guar gum, locust bean gum, pluronic, agar, It may include at least one selected from the group consisting of carrageenan, xanthan gum, and gellan gum.

In an exemplary embodiment, the alginate may be a calcium salt of alginic acid.

In an exemplary embodiment, the alginate grains may be insoluble in water.

In one aspect, the present invention provides a hydrogel sheet comprising a hydrophilic polymer, a calcium salt and an alginate, wherein the hydrogel sheet is a hydrogel sheet in which alginate grains remain when bathed in water at 80°C.

In addition, in one aspect, the present invention comprises the step of forming alginate grains by crosslinking alginate in the hydrogel by introducing a second agent containing an alkali metal salt of alginic acid to a first agent containing a hydrophilic polymer and a calcium salt. It provides a method of manufacturing a hydrogel sheet.

In one aspect, the hydrogel sheet according to the present invention includes alginate grains in the hydrogel, and has high strength and excellent adhesion.

In one aspect, the hydrogel sheet according to the present invention is excellent in aesthetics with a unique appearance including alginate grains.

1 is a photograph of a hydrogel sheet according to an embodiment of the present invention dissolved in a bath.
2 is a photograph of a hydrogel sheet according to an embodiment of the present invention dissolved and filtered through a mesh.

Hereinafter, the present invention will be described in detail.

In one aspect, the present invention provides a gelling composition comprising a first agent including a hydrophilic polymer and a calcium salt, and a second agent including an alkali metal salt of alginic acid.

In one embodiment, the hydrophilic polymer is for forming a hydrogel, galactomannan (galactomannan), glucomannan (glucomannan), guar gum (guar gum), locust bean gum (locust bean gum), pluronic (pluronic) ), agar, carrageenan, xanthan gum, and gellan gum.

In one embodiment, the calcium salt is for crosslinking the alginate, and there is no particular limitation as long as it exists as a compound in the form of a divalent calcium salt, for example, calcium hydroxide (Ca(OH) ₂ ), calcium carbonate (CaCO ₃ ), calcium chloride (CaCl ₂ ) and calcium lactate (C ₆ H ₁₀ CaO ₆ ) may include one or more selected from the group consisting of.

In one embodiment, the alkali metal salt of alginic acid may include at least one selected from the group consisting of sodium alginate and potassium alginate.

In one aspect, the present invention provides a hydrogel sheet including a hydrogel and alginate grains contained within the hydrogel.

In one embodiment, the hydrogel is galactomannan, glucomannan, guar gum, locust bean gum, pluronic, agar, carrageenan It may include at least one selected from the group consisting of (carrageenan), xanthan gum, and gellan gum. These hydrogels can contain a large amount of moisture, so they have excellent cooling feeling, moisturizing power and adhesion.

In one embodiment, the alginate grains may be a calcium salt of alginic acid. The alginate grains are formed by crosslinking alginate with calcium ions in the hydrogel. Alginate grains formed by crosslinking in the hydrogel may be entangled with the hydrogel to improve the strength of the sheet. The shape of the alginate grains is not particularly limited, but may be in various shapes such as tetrahedral, pentahedral, hexahedron, octahedron, dodecahedron, icosahedron, spherical, elliptical, cylinder, radial, and the like.

In one embodiment, it is preferable that the alginate grains are insoluble in water. Specifically, the alginate grains may be insoluble in water of 40°C or more, 45°C or more, 50°C or more, 55°C or more, 60°C or more, 65°C or more, 70°C or more, 75°C or more, or 80°C or more.

In one embodiment, the content of the alginate grains may be 5 to 20% by weight based on the total weight of the sheet. When the content of the alginate grains is less than 5% by weight, the strength of the hydrogel sheet decreases, and when the content of the alginate grains is less than 20% by weight, adhesion and strength are decreased due to excessive alginate grains. Specifically, the content of the alginate grains is 5% by weight or more, 6% by weight or more, 7% by weight or more, 8% by weight or more, 9% by weight or more, 10% by weight or more, 11% by weight or more, or 12% based on the total weight of the sheet. It may be 20% by weight or less, 19% by weight or less, 18% by weight or less, 17% by weight or less, 16% by weight or less, 15% by weight or less, 14% by weight or less, or 13% by weight or less.

In one embodiment, the thickness of the hydrogel sheet may be 0.1 to 5 mm. When the thickness of the hydrogel sheet is less than 0.1 mm, mechanical properties may be deteriorated, and when the thickness of the hydrogel sheet is more than 5 mm, adhesion is lowered, so it may not be easy to attach the hydrogel sheet to the skin. Specifically, the thickness of the hydrogel sheet is 0.1 mm or more, 0.2 mm or more, 0.3 mm or more, 0.4 mm or more, 0.5 mm or more, 0.6 mm or more, 0.7 mm or more, 0.8 mm or more, 0.9 mm or more, 1 mm or more, 1.1 mm or more, 1.2 mm or more, 1.3 mm or more, 1.4 mm or more, or 1.5 mm or more, and 5 mm or less, 4.9 mm or less, 4.8 mm or less, 4.7 mm or less, 4.6 mm or less, 4.5 mm or less, 4.4 mm or less, 4.3 mm or less, 4.2 mm or less, 4.1 mm or less, 4 mm or less, 3.9 mm or less, 3.8 mm or less, 3.7 mm or less, 3.6 mm or less, or 3.5 mm or less.

In one embodiment, the hydrogel sheet may further include an additive material having various functions as needed. For example, the additives are retinol, retinyl palmitate, adenosine, polyethoxyeltide retinamide, arbutin, black oak extract, licorice, ethyl ascorbylase, ascorbyl glucoside, magnesium ascorbyl phosphate, chima mushroom polysaccharide, Niacinamide, N-acetylglucosamine, ivy extract, fancy extract, chamomile, soybean extract, green tea liquid, vitamin C, magnesium ascorbyl phosphate, ascorbyl acid 2-glucoside, Paeoniflorin, kinetin, alpha-hydroxy acid, candelilla wax, alpha bisabolol, aloe vera, mange star, gull, pine needle extract, collagen extract, grape extract, It may be one or more selected from the group consisting of quince extract, green tea extract, ginkgo extract, seaweed extract, lavender, tea tree, lemon balm, honey, mint, avocado oil, and soybean oil.

In one embodiment, the hydrogel sheet may be used as such, but in order to prevent damage to the hydrogel sheet and protect the skin contact surface of the sheet, the lower surface of the hydrogel sheet is placed on a mold tray. It may be accommodated, and a release film may be attached to the upper surface. Materials of these mold trays and release films are polyethylene terephthalate (PET), polyethylene (PE), polyester (PS), aluminum, nylon, polypropylene (PP), oriented polypropylene (OPP), casting poly It may be propylene (Casting Poly Propylene; CPP), High Density Polyethylene (HDPE), Low Density Polyethylene (LDPE), or Linear Low Density Polyethylene (LLDPE).

In one embodiment, the hydrogel sheet is a component used in a conventional hydrogel mask in addition to the above components, for example, oils, powders, polymer compounds, moisturizers, fragrances, antioxidants, preservatives, cosmetic ingredients other than the above. And the like can be appropriately contained within a range that does not impair the effects of the present invention.

In one aspect, the present invention provides a hydrogel sheet comprising a hydrophilic polymer, a calcium salt, and an alginate, wherein the hydrogel sheet is a hydrogel sheet in which alginate grains remain when bathed in water.

In one embodiment, the hydrophilic polymer is galactomannan (galactomannan), glucomannan (glucomannan), guar gum (guar gum), locust bean gum (locust bean gum), pluronic (pluronic), agar (agar), Carrageenan (carrageenan), xanthan gum (xanthan gum) and may include one or more selected from the group consisting of gellan gum (gellan gum), the calcium salt, calcium hydroxide (Ca(OH) ₂ ), calcium carbonate (CaCO ₃ ), calcium chloride (CaCl ₂ ) and calcium lactate (C ₆ H ₁₀ CaO ₆ ) may include one or more selected from the group consisting of, the alginate is sodium alginate and potassium alginate (Potassium alginate) It may include one or more selected from the group consisting of, but is not limited thereto.

In one embodiment, the hydrogel sheet is a hydrogel sheet in which alginate grains remain when bathed in water, and the temperature of the water is 40°C or more, 45°C or more, 50°C or more, 55°C or more, 60°C or more, 65°C It may be above, 70°C or higher, 75°C or higher, or 80°C or higher.

In one aspect, the present invention comprises the step of forming alginate grains by crosslinking the alginate in the hydrogel by introducing a second agent containing an alkali metal salt of alginic acid to a first agent containing a hydrophilic polymer and a calcium salt. It provides a method of manufacturing a hydrogel sheet.

In one embodiment, the step of forming the alginate grains may be performed by homomixing while adding a second agent to the first agent.

In one embodiment, the hydrophilic polymer is for forming a hydrogel, galactomannan (galactomannan), glucomannan (glucomannan), guar gum (guar gum), locust bean gum (locust bean gum), pluronic (pluronic) ), agar, carrageenan, xanthan gum, and gellan gum.

In one embodiment, the calcium salt is for crosslinking the alginate, and there is no particular limitation as long as it exists as a compound in the form of a divalent calcium salt, for example, calcium hydroxide (Ca(OH) ₂ ), calcium carbonate (CaCO ₃ ), calcium chloride (CaCl ₂ ) and calcium lactate (C ₆ H ₁₀ CaO ₆ ) may include one or more selected from the group consisting of.

In one embodiment, the alkali metal salt of alginic acid may include at least one selected from the group consisting of sodium alginate and potassium alginate.

Hereinafter, the present invention will be described in more detail through examples. These examples are for illustrative purposes only, and it will be apparent to those of ordinary skill in the art that the scope of the present invention is not construed as being limited by these examples.

[Example 1: Preparation of hydrogel sheet]

According to the composition of Table 1 below, a hydrogel sheet of Example 1 was prepared (unit:% by weight). First, purified water was heated to 80° C., and then raw materials 1 to 3 were added and stirred to prepare a first agent. Subsequently, the raw materials 5 to 16 were heated to 80°C and stirred using an azimixer to prepare a second agent, and then homomixed while adding the first agent to the second agent to obtain a coating solution. The coating solution was applied to a thickness of 2 mm on a glass plate and then cooled to prepare a hydrogel sheet.

turn Ingredient name Example 1 Comparative Example 1 Comparative Example 2 Part 1 One Potassium alginate 5 0 0 2 Titanium dioxide 0.5 0 0 3 Butylene Glycol 10 0 0 4 Purified water To 100 0 0 Second 5 Carriginan 1.5 1.5 1.5 6 Roast bean gum 0.7 0.7 0.7 7 Baby 0.2 0.2 0.2 8 Potassium alginate 0 0.5 0 9 Potassium hydroxide 0.02 0.02 0.02 10 Calcium chloride 0.5 0.05 0 11 antiseptic 0.2 0.2 0.2 12 Ethylhexyl glycerin 0.05 0.05 0.05 13 glycerin 15 15 15 14 Butylene Glycol 5 5 5 15 Spices 0.05 0.05 0.05 16 Purified water To 100 To 100 To 100

[Comparative Example]

Hydrogel sheets of Comparative Examples 1 and 2 were prepared according to the composition of Table 1 (unit:% by weight). After heating purified water to 80° C., raw materials 5 to 16 were added and stirred to prepare a coating solution, and then the coating solution was applied to a thickness of 2 mm on a glass plate and cooled to prepare a hydrogel sheet.

[Experimental Example 1: Confirmation of the presence or absence of insoluble alginate grains]

After dissolving Example 1 and Comparative Examples 1 and 2 in purified water at 80° C., it was filtered through 25 mesh (710 μm) to check the presence or absence of insoluble alginate grains, and the results are shown in FIGS.

As shown in FIG. 1, the hydrogel sheets of Comparative Examples 1 and 2 were completely dissolved after bathing, but in Example 1, alginate grains were not dissolved. In addition, when Comparative Examples 1 and 2 dissolved in a bath was filtered with 25 mesh, it was filtered without remaining, but in the case of Example 1, it was confirmed that alginate grains were filtered as shown in FIG. 2.

[Experimental Example 2: Measurement of tensile strength and adhesion]

The tensile strength of Example 1 and Comparative Examples 1 and 2 was measured using a physical property analyzer (Texture analyzer, Ta.XT Plus, Stable Micro System) under the measurement conditions of Table 2 below, and the results are shown in Table 3.

Sample size 80mm x 15mm x 2mm speed 20mm/min Travel distance 100mm

In addition, sensory evaluation was performed on 10 women aged 30 to 45 years to evaluate the skin adhesion of Example 1 and Comparative Examples 1 and 2. After attaching the hydrogel sheet to the face for 30 minutes, the degree of skin adhesion was measured on a 5-point scale (1 point: very poor adhesion, 2 points: insufficient adhesion, 3 points: normal adhesion, 4 points: excellent adhesion, 5 points: very adhesion) Excellent), and the numerical values were averaged and shown in Table 3.

Tensile strength (N/cm ² ) Adhesion Example 1 10.03 4.3 Comparative Example 1 9.61 2.8 Comparative Example 2 6.51 4.5

As shown in Table 3, Comparative Example 1 has ^{excellent tensile strength of 9.61 N/cm 2} but poor adhesion, and Comparative Example 2 has excellent adhesion but low tensile strength of 6.51 N/cm ² , whereas alginate grains are included. In the case of Example 1, it was confirmed that both tensile strength and adhesion were excellent. When the tensile strength is 8 N/cm ² or more, it is not torn when the user pulls it while using the hydrogel sheet, but it was found that Example 1 has excellent skin adhesion without tearing well when pulled.

Claims (13)

A first agent containing a hydrophilic polymer and a calcium salt; And a second agent containing an alkali metal salt of alginic acid. The method of claim 1,
The hydrophilic polymer is galactomannan, glucomannan, guar gum, locust bean gum, pluronic, agar, carrageenan, xanthan gum (xanthan gum) and gellan gum (gellan gum) comprising at least one selected from the group consisting of, gelling composition. The method of claim 1,
The calcium salt comprises at least one selected from the group consisting of calcium hydroxide, calcium carbonate, calcium chloride and calcium lactate. The method of claim 1,
The alkali metal salt of alginic acid comprises at least one selected from the group consisting of sodium alginate and potassium alginate. A hydrogel sheet comprising a hydrogel and alginate grains contained within the hydrogel. The method of claim 5,
The hydrogel is galactomannan, glucomannan, guar gum, locust bean gum, pluronic, agar, carrageenan, xanthan gum (xanthan gum) and gellan gum (gellan gum) comprising at least one selected from the group consisting of, a hydrogel sheet. The method of claim 5,
The alginate grains are insoluble in water, a hydrogel sheet. The method of claim 5,
The alginate grains are calcium salts of alginic acid, a hydrogel sheet. The method of claim 5,
The sheet is a hydrogel sheet having a tensile strength of 10 N/cm ^{2 or more as measured by a texture analyzer.} As a hydrogel sheet containing a hydrophilic polymer, a calcium salt and an alginate,
When the hydrogel sheet is bathed in water of 80° C. or higher, alginate grains remain, a hydrogel sheet. As a method of manufacturing a hydrogel sheet,
The hydrogel sheet is the hydrogel sheet of any one of claims 5 to 9,
A method for producing a hydrogel sheet comprising the step of forming alginate grains by crosslinking the alginate inside the hydrogel by adding a second agent including an alkali metal salt of alginic acid to a first agent containing a hydrophilic polymer and a calcium salt. The method of claim 11,
The calcium salt comprises at least one selected from the group consisting of calcium hydroxide, calcium carbonate, calcium chloride and calcium lactate. The method of claim 11,
The alginate alkali metal salt comprises at least one selected from the group consisting of sodium alginate and potassium alginate.

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