KR20210031715A - 관절내 스테로이드의 합병증을 감소시키는 방법 - Google Patents

관절내 스테로이드의 합병증을 감소시키는 방법 Download PDF

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Publication number
KR20210031715A
KR20210031715A KR1020217003687A KR20217003687A KR20210031715A KR 20210031715 A KR20210031715 A KR 20210031715A KR 1020217003687 A KR1020217003687 A KR 1020217003687A KR 20217003687 A KR20217003687 A KR 20217003687A KR 20210031715 A KR20210031715 A KR 20210031715A
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KR
South Korea
Prior art keywords
weeks
steroid
pharmaceutical composition
joint
administered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020217003687A
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English (en)
Korean (ko)
Inventor
슈-팡 쉬
포-춘 창
밍-주 우
Original Assignee
타이완 리포좀 캄파니 리미티드
티엘씨 바이오파머슈티컬즈 인코포레이티드
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Application filed by 타이완 리포좀 캄파니 리미티드, 티엘씨 바이오파머슈티컬즈 인코포레이티드 filed Critical 타이완 리포좀 캄파니 리미티드
Priority to KR1020257019987A priority Critical patent/KR20250093579A/ko
Publication of KR20210031715A publication Critical patent/KR20210031715A/ko
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
KR1020217003687A 2018-07-09 2019-07-08 관절내 스테로이드의 합병증을 감소시키는 방법 Ceased KR20210031715A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020257019987A KR20250093579A (ko) 2018-07-09 2019-07-08 관절내 스테로이드의 합병증을 감소시키는 방법

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862695763P 2018-07-09 2018-07-09
US62/695,763 2018-07-09
US201962839231P 2019-04-26 2019-04-26
US62/839,231 2019-04-26
PCT/US2019/040794 WO2020014118A1 (en) 2018-07-09 2019-07-08 Methods to reduce complications of intra-articular steroid

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020257019987A Division KR20250093579A (ko) 2018-07-09 2019-07-08 관절내 스테로이드의 합병증을 감소시키는 방법

Publications (1)

Publication Number Publication Date
KR20210031715A true KR20210031715A (ko) 2021-03-22

Family

ID=67441711

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020217003687A Ceased KR20210031715A (ko) 2018-07-09 2019-07-08 관절내 스테로이드의 합병증을 감소시키는 방법
KR1020257019987A Pending KR20250093579A (ko) 2018-07-09 2019-07-08 관절내 스테로이드의 합병증을 감소시키는 방법

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020257019987A Pending KR20250093579A (ko) 2018-07-09 2019-07-08 관절내 스테로이드의 합병증을 감소시키는 방법

Country Status (12)

Country Link
US (1) US12083138B2 (https=)
EP (1) EP3820479B1 (https=)
JP (1) JP7463306B2 (https=)
KR (2) KR20210031715A (https=)
CN (1) CN112469420A (https=)
AU (1) AU2019301542B2 (https=)
BR (1) BR112021000316A2 (https=)
CA (1) CA3105743A1 (https=)
SG (1) SG11202100054YA (https=)
TW (1) TWI857961B (https=)
WO (1) WO2020014118A1 (https=)
ZA (1) ZA202100604B (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023019192A1 (en) * 2021-08-11 2023-02-16 Board Of Regents, The University Of Texas System Dry liposome formulations and related methods thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4938949A (en) 1988-09-12 1990-07-03 University Of New York Treatment of damaged bone marrow and dosage units therefor
DE10255106A1 (de) * 2002-11-24 2004-06-09 Novosom Ag Liposomale Glucocorticoide
US20130296267A1 (en) * 2008-01-18 2013-11-07 Horst Kief Agent for intra-articular injection
US8956600B2 (en) 2009-08-10 2015-02-17 Taiwan Liposome Co. Ltd. Ophthalmic drug delivery system containing phospholipid and cholesterol
UA111162C2 (uk) 2010-08-04 2016-04-11 Флекшен Терап'Ютікс, Інк. Ін'єкційна композиція ацетоніду триамцинолону для лікування болю
RU2660585C2 (ru) * 2012-02-10 2018-07-06 Тайвэн Липосом Компани, Лтд. Фармацевтическая композиция для уменьшения осложнений применения стероидных препаратов при лечении офтальмологических заболеваний
SI2854769T1 (sl) * 2012-07-05 2023-09-29 Taiwan Liposome Company, Ltd. Postopki za zdravljenje artritisa
TWI845973B (zh) 2015-01-21 2024-06-21 美商桑紐爾製藥公司 醫藥配方

Also Published As

Publication number Publication date
EP3820479B1 (en) 2026-03-11
AU2019301542A1 (en) 2021-02-25
JP2021532074A (ja) 2021-11-25
TWI857961B (zh) 2024-10-11
AU2019301542B2 (en) 2025-04-03
TW202007398A (zh) 2020-02-16
CA3105743A1 (en) 2020-01-16
JP7463306B2 (ja) 2024-04-08
EP3820479A1 (en) 2021-05-19
US12083138B2 (en) 2024-09-10
SG11202100054YA (en) 2021-02-25
ZA202100604B (en) 2025-05-28
CN112469420A (zh) 2021-03-09
BR112021000316A2 (pt) 2021-04-06
WO2020014118A1 (en) 2020-01-16
KR20250093579A (ko) 2025-06-24
US20210196733A1 (en) 2021-07-01

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