KR20210015576A - Multiple emulsion type cosmetic composition - Google Patents

Abstract

The present specification describes a cosmetic composition comprising a multiple emulsion formulation, comprising: droplets including an inner phase and an outer phase; and an outermost phase. The cosmetic composition of the present invention can provide excellent formulation stability due to the distribution of the droplets very close to the outermost phase.

Description

Cosmetic composition of multi-emulsion formulation {MULTIPLE EMULSION TYPE COSMETIC COMPOSITION}

The present specification describes a cosmetic composition having a stable multiple emulsion formulation.

Cosmetic compositions of multiple emulsion formulations such as O/W/O (Oil-in-Water-in-Oil) or W/O/W (Water-in-Oil-in-Water) are generally used as an emulsifier on the internal and external surfaces. Active agents have been used, but in this case, there is a problem that the formulation itself is structurally complex and thermodynamically unstable. In the case of an emulsion formulation using a surfactant for the existing internal and external surfaces, the interfacial tension acts to minimize the surface area of the droplets dispersed in the continuous phase due to the Laplace effect, and the pressure of the internal liquid droplets becomes higher than the pressure of the external liquid. This is because the internal liquid phase is subjected to a force to move to the trauma due to this pressure difference, making the multiple emulsion formulation unstable.

Korean Patent Application Publication No. 10-2005-0097587

Ferreira T and Rasband WS. “ImageJ User Guide ― IJ 1.46”, imagej.nih.gov/ij/docs/guide/, 2010-2012

In one aspect, the problem to be solved by the present invention is to provide a cosmetic composition of multiple emulsion formulations having excellent formulation stability.

In order to solve the above problem, an embodiment of the present invention

Droplets including internal and trauma; And it is a multi-emulsified formulation comprising the outermost phase, and satisfying at least one of (i) to (iii) provides a cosmetic composition:

(i) The distance between two adjacent droplets distributed in the formulation is 5 μm or less, the distance is calculated for droplets with an average particle size of 2 μm to 50 μm, and the distance between the droplets is calculated by Equation 1:

[Equation 1]

Distance between droplets = (A)-(r+R)

In Equation 1, A is the distance between the centers of two adjacent droplets of the composition, and r and R are the respective radii of the two adjacent droplets measured on the same line as A;

(ii) in the microscopic image of the composition, the sum of the areas of the droplets distributed in the formulation with respect to the total area of the image 100% is 80% or more and less than 100%, and the microscopic image is taken at a magnification of 1000; And

(iii) The content of the droplets including the inner and outer wounds is greater than 80% to less than 100% by weight based on the total weight of the composition.

The cosmetic composition according to the present invention has a structure in which droplets distributed in the outermost image of the formulation are very dense and adjacent. In the present invention, since the adjacent droplets have a force to push each other in the outermost wound as described above, it is possible to stably maintain a multi-emulsified formulation of the inner wound-traumatic-outermost phase. The present invention may stably contain skin oil-soluble ingredients having low solubility or low stability in the inner phase by having the above-described multiple emulsion formulation. In addition, the present invention can provide a refreshing feeling of moisture and moisturizing feeling such as bursting of water droplets on the skin as droplets in the formulation burst when used.

1 is a schematic diagram of a conventional multi-emulsified cosmetic composition as W/O/W (Water-in-Oil-in-Water) and O/W/O (Oil-in-Water-in-Oil) formulations.
2 is a microscopic image of an O/W/O (Oil-in-Water-in-Oil) formulation as a conventional multiple emulsion formulation cosmetic composition. (Scale bar 10μm)
3 is a schematic diagram of a multi-emulsion formulation cosmetic composition according to an embodiment of the present invention.
4 is a microscopic image of a cosmetic composition for multi-emulsion formulation according to an embodiment of the present invention. (Scale bar 10μm)
5 is a photograph showing the results of a comparative experiment between freezing point and formulation stability according to the content of polyol and ethanol contained in the composition as an embodiment of the present invention. (From the left, Example 1, Example 2, Example 3, Example 4, Example 5, Example 6, Example 7, Example 8)
6 is a microscope image of Comparative Example 2 of the present invention. The arrow line is an example of a baseline for measuring the distance between adjacent particles in the formulation.
7 is a microscope image of Comparative Example 4 of the present invention. The arrow line is an example of a baseline for measuring the distance between adjacent particles in the formulation.
8 is a microscope image of Example 10, which is an example of the present invention. The arrow line is an example of a baseline for measuring the distance between adjacent particles in the formulation.
9 is a photograph showing the results of a comparative experiment on the formulation stability of a composition according to an embodiment of the present invention. (From the left, Comparative Example 1, Comparative Example 2, Comparative Example 3, Comparative Example 4, Example 9, Example Example 10)
FIG. 10 shows a part outside of the droplet in blue in the microscope image of FIG. 8.
11 is a diagram showing the results of an experiment comparing the oiliness of an embodiment and a comparative example of the present invention.
12 is a diagram showing the results of a comparison test of the thickness of an embodiment and a comparative example of the present invention.
13 is a microscope image showing the result of confirming the precipitation titer of an efficacious substance in the formulation of Comparative Example of the present invention. (Scale bar 10μm)
14 is a microscope image showing the result of confirming the precipitation titer of an efficacious substance in an Example formulation of the present invention. (Scale bar 10μm)

The present invention relates to a cosmetic composition for a multi-emulsion formulation, and will be described in detail below with reference to the accompanying drawings, embodiments of the present invention.

An embodiment of the present invention is a droplet (droplet) including an internal wound and a trauma; And it provides a multi-emulsion formulation cosmetic composition comprising the outermost phase.

Attached Figures 1 and 2 shows an exemplary form of a conventional multi-emulsion formulation cosmetic composition, Figures 3 and 4 show an exemplary form of the present invention. 1 and 2, conventional W/O/W (Water-in-Oil-in-Water) and O/W/O (Oil-in-Water-in-Oil) of FIG. The multi-emulsified formulation of had a structure in which droplets with internal and external wounds were dispersed within the outermost phase of the aqueous phase or oil phase. On the other hand, as shown in Figs. 3 and 4, the composition according to the embodiments of the present invention has a structure in which the droplets including the inner wound and the trauma in the formulation are very close to each other or have a structure in close contact with each other, so that the force pushing each other between the droplets is It maintains the formulation stably, so that phase separation of the composition does not occur even during long-term storage.

In an embodiment of the present invention, the composition may satisfy the sum of the areas of droplets distributed in the formulation with respect to 100% of the total area of the composition image in the microscopic image photographing the composition of 80% or more and less than 100%. In this case, the microscope image may be taken at 1000 magnification. In one embodiment, the microscopic image is taken using a microscope (Nikon, model name: Eclipse 80i Microscope) after preparing the composition and storing it at 25°C.

As an embodiment, the method of analyzing the sum of the areas of the droplets from the microscope image is not limited to the method and may be included as long as the sum of the areas of the droplets can be calculated. As an example, the method of calculating the sum of the areas of the droplets from the microscope image includes calculating using an Image-Pro® 10 Image Analysis Software (Manufacturer: MEDIA CYBERNETICS) program. I can. As an example, the method of calculating the sum of the areas of the droplets from the microscopic image may include calculating using Image J, an image processing and analysis program made and provided by the National Institute of Health and Health (NIH). The Image J can be downloaded and used from the website https://imagej.nih.gov/ij/. How to use Image J is Ferreira T and Rasband WS. "ImageJ User Guide-IJ 1.46", imagej.nih.gov/ij/docs/guide/, 2010-2012, the entire document is incorporated herein by reference.

The microscope image may have a size of 700 μm X 500 μm and a shape of a rectangle. As an example, the total area of the droplets distributed in the formulation relative to the total area of the composition image 100% is 80% or more, 81% or more, 82% or more, 83% or more, 84% or more, 85% or more, 86% or more , 87% or more, 88% or more, 89% or more, 90% or more, 91% or more, 92% or more, 93% or more, 94% or more, 95% or more, 96% or more, 97% or more, 98% or more, or 99 May be greater than or equal to %.

The size of the droplets included in the composition of the present invention and the degree of concentration between the droplets may be appropriately adjusted by the user in order to provide a stable formulation without phase separation.

As an example, the average particle size of the droplets included in the present invention may be 2 μm to 50 μm. In the present specification, the particle size of the droplet means the largest diameter in the particle, and the average particle size of the droplet means the average of the particle sizes of at least 90% or more droplets distributed in the composition. Specifically, the average particle size of the droplets is at least 90%, 91% or more, 92% or more, 93% or more, 94% or more, 95% or more, 96% with respect to the total number of droplets among the droplets distributed in the composition. It is a value obtained by selecting the droplets corresponding to above, 97% or more, 98% or more, or 99% or more, and calculates the average of the largest diameter values measured in each of these particles. More specifically, the average particle size is 2 μm or more, 3 μm or more, 4 μm or more, 5 μm or more, 6 μm or more, 7 μm or more, 8 μm or more, 9 μm or more, 10 μm or more, 11 μm or more, 12 μm Or more, 13 μm or more, 14 μm or more, 15 μm or more, 16 μm or more, 17 μm or more, 18 μm or more, 19 μm or more, 20 μm or more, 21 μm or more, 22 μm or more, 23 μm or more, 24 μm or more, 25 μm or more, 26 μm or more, 27 μm or more, 28 μm or more, 29 μm or more, 30 μm or more, 31 μm or more, 32 μm or more, 33 μm or more, 34 μm or more, 35 μm or more, 36 μm or more, 37 μm Or more, 38 μm or more, 39 μm or more, 40 μm or more, 41 μm or more, 42 μm or more, 43 μm or more, 44 μm or more, 45 μm or more, 46 μm or more, 47 μm or more, 48 μm or more, 49 μm or more, or It may be 49.9 μm or more. Alternatively, the average of the particle size is 50 μm or less, 49 μm or less, 48 μm or less, 47 μm or less, 46 μm or less, 45 μm or less, 44 μm or less, 43 μm or less, 42 μm or less, 41 μm or less, 40 μm Or less, 39 μm or less, 38 μm or less, 37 μm or less, 36 μm or less, 35 μm or less, 34 μm or less, 33 μm or less, 32 μm or less, 31 μm or less, 30 μm or less, 29 μm or less, 28 μm or less, 27 μm or less, 26 μm or less, 25 μm or less, 24 μm or less, 23 μm or less, 22 μm or less, 21 μm or less, 20 μm or less, 19 μm or less, 18 μm or less, 17 μm or less, 16 μm or less, 15 μm Or less, 14 μm or less, 13 μm or less, 12 μm or less, 11 μm or less, 10 μm or less, 9 μm or less, 8 μm or less, 7 μm or less, 6 μm or less, 5 μm or less, 4 μm or less, 3 μm or less, or It may be less than 2 μm.

As an example, the distance between two adjacent droplets in the formulation may be 5 μm or less, and in this case, the distance between the droplets may be calculated by Equation 1.

[Equation 1]

Distance between droplets = (A)-(r+R)

In Equation 1, A is the distance between the centers of two adjacent droplets of the composition, and r and R are the respective radii of the two adjacent droplets measured on the same line as A. Here, the radius means the distance from the center of the droplet to the interface.

As an example, in the present specification, the term "adjacent" means that no other droplet exists between two droplets, and in this case, the droplets all mean droplets including an inner wound and a trauma.

As an example, the distance between two adjacent droplets in the formulation is measured for droplets of at least 90% of the total number of droplets distributed in the composition. Specifically, the distance between the droplets is at least 90% or more, 91% or more, 92% or more, 93% or more, 94% or more, 95% or more, 96% or more, 97% with respect to the total number of droplets among the droplets distributed in the composition. Droplets corresponding to above, 98% or more, or 99% or more are selected, and a distance between two adjacent droplets may be measured.

As an example, the distance may be calculated for a droplet having an average particle size of 2 μm to 50 μm.

As an example, the average distance between two adjacent droplets in the formulation is 5 μm or less, 4.5 μm or less, 4 μm or less, 3.5 μm or less, 3 μm or less, 2.5 μm or less, 2 μm or less, 1.5 μm or less, 1 μm or less, 0.5 May be μm or less or 0.1 μm or less, and may be on average 0 μm or more, 0.1 μm or more, 0.5 μm or more, 1.0 μm or more, 1.5 μm or more, 2.0 μm or more, 2.5 μm or more, 3 μm or more, 4 μm or more or 4.9 μm or more have.

As an example, the content of the droplets contained in the composition of the present invention is not limited as long as it can have a uniformly dense structure with each other, and may be appropriately adjusted by the user to provide a stable formulation. For example, the droplets are greater than 80%, 81% or more, 82% or more, 83% or more, 84% or more, 85% or more, 86% or more, 87% by weight based on the total weight of the composition Or more, 88% or more, 89% or more, 90% or more, 91% or more, 92% or more, 93% or more, 94% or more, 95% or more, 96% or more, 97% by weight It may be included in an amount of 98% by weight or more, or 99% by weight or more. Or, for example, the oil-in-water droplets are less than 100%, 99% or less, 98% or less, 97% or less, 96% or less, 95% or less, 94% or less, based on the total weight of the composition, 93% or less, 92% or less, 91% or less, 90% or less, 89% or less, 88% or less, 87% or less, 86% or less, 85% or less, 84% or less, 83% by weight or less, 82% by weight or less, or 81% by weight or less may be included. Or, as an embodiment, the droplets including the inner and outer wounds are more than 80% by weight to less than 100% by weight, specifically more than 80% to 95% by weight, more specifically 85 to 90% by weight based on the total weight of the composition. Alternatively, it may be included in 90% to 95% by weight.

As an embodiment of the present invention, the multi-emulsified formulation is an oily inner wound; Prime Minister Trauma; And it may be an O / W / S (Oil-in-Water-in-Silicon Oil) formulation including the outermost phase containing a silicone oil.

As an embodiment of the present invention, the inner phase of the composition may include oil, and the type of oil may include ester oil, hydrocarbon oil, natural oil, silicone oil, or a mixture thereof. Not limited. Specifically, the inner wound is squalane, caprylic/capric triglyceride, cetyl ethylhexanoate, 2-octyldodecanol, pentaerythritol terra-2 -It may contain one or more oils selected from the group consisting of ethylhexanoate (Pentaerythritol Tetra-2-Ethylhexanoate), or a mixture thereof. As an example, the inner wound may further include an effective ingredient such as a whitening agent, an anti-wrinkle agent, a sunscreen agent, and an antioxidant as an oil-soluble ingredient in addition to oil. As an example, a water-soluble component for the trauma may include a moisturizing agent, a whitening agent, a wrinkle improving agent, a sunscreen agent, an antioxidant, or a mixture thereof. For example, the inner wound may further include at least one active ingredient selected from the group consisting of thymol trimethoxycinnamate, oil-soluble vitamins, fat-soluble physiologically active ingredients, oil-soluble licorice and polyphenols. As a specific example, the thymol trimethoxycinnamate may be Melasolv ^™ (Melasolv ^™ , AMOREPACIFIC), and the oil-soluble vitamin may include at least one of retinol and tocopherol. The fat-soluble bioactive component may include at least one of linolenic acid and glycolipid.

As an embodiment of the present invention, the external surface of the composition may include a polyol.

The polyol included in the above embodiment may mean a polyhydric alcohol, for example, a fatty alcohol having two or more hydroxyl groups (-OH). Those having two hydroxyl groups are called glycols or diols, those having three hydroxyl groups are called triols (eg glycerol), and those having four hydroxyl groups are called tetraols (eg pentaerythritol). As an example, the polyol is polyethylene glycol, polypropylene glycol, dipropylene glycol, propylene glycol, butylene glycol, glycerin, polyglycerin-3, propanediol, sorbitol, erythritol, xylitol, maltitol, ethylhexanediol, 1,2 -Hexanediol, sebum/sebum/polybutylene glycol-8/5/3 may contain at least one selected from the group consisting of glycerin and pentylene glycol. The content of the polyol contained in the cosmetic composition of the present invention is not limited and may be appropriately adjusted by the user. As an embodiment, the polyol is 1% by weight or more, 2% by weight or more, 3% by weight or more, 4% by weight or more, 5% by weight or more, 6% by weight or more, 7% by weight or more, 8% by weight based on the total weight of the composition. Or more, 9% or more, 10% or more, 11% or more, 12% or more, 13% or more, 14% or more, 15% or more, 16% or more, 17% or more, 18% or more Or more, 19% or more, 20% or more, 21% or more, 22% or more, 23% or more, 24% or more, 25% or more, 26% or more, 27% or more, 28% by weight It may be included in more than, 29% by weight or more, or 30% by weight or more. In addition, as an example, the polyol is 30% by weight or less, 29% by weight or less, 28% by weight or less, 27% by weight or less, 26% by weight or less, 25% by weight or less, 24% by weight or less based on the total weight of the composition. Wt% or less, 22 wt% or less, 21 wt% or less, 20 wt% or less, 19 wt% or less, 18 wt% or less, 17 wt% or less, 16 wt% or less, 15 wt% or less, 14 wt% or less, 13 Wt% or less, 12 wt% or less, 11 wt% or less, 10 wt% or less, 9 wt% or less, 8 wt% or less, 7 wt% or less, 6 wt% or less, 5 wt% or less, 4 wt% or less, 3 It may be included in wt% or less, 2 wt% or less, or 1 wt%. Alternatively, as an embodiment, the composition may contain 1 to 30% by weight, for example, 15 to 25% by weight, based on the total weight of the polyol. As an example, the composition may contain the polyol in an amount of 5% to 35% by weight, for example, 20% to 30% by weight based on the total weight of the trauma.

이하로 낮추기 위하여, 상기 에탄올을 조성물 총 중량에 대하여 3 내지 10 중량%, 예를 들어 4 내지 9 중량%, 예를 들어 5 내지 9 중량%, 예를 들어 6 내지 8 중량%로 포함할 수 있다. 일 실시예로서 상기 에탄올을 상기 외상 총 중량에 대하여 5 중량% 내지 12 중량%로 포함할 수 있다. 어는 점이 낮을 경우 조성물 제형내 외상에 포함된 수상의 물이 얼면서 입자가 팽창되어 제형이 분리될 가능성이 감소하므로 제형이 더 안정적으로 유지될 수 있다. As an embodiment, the trauma may further include a thickener and/or a solvent. As an example, the solvent included in the outer phase may include at least one of water and ethanol, preferably water, more preferably water and ethanol. As an example, the trauma has a freezing point of -15 so as not to freeze even when the composition of the present invention is stored frozen for a long time.

In order to be lowered below, the ethanol may be included in 3 to 10% by weight, for example 4 to 9% by weight, for example 5 to 9% by weight, for example 6 to 8% by weight, based on the total weight of the composition. . As an example, the ethanol may be included in an amount of 5% to 12% by weight based on the total weight of the trauma. When the freezing point is low, the water in the water phase contained in the trauma in the composition formulation freezes and the particles expand and the likelihood of separation of the formulation decreases, so that the formulation can be more stable.

In addition, as an embodiment, the trauma may further include a water-soluble moisturizer, a water-soluble active ingredient, and the like. For example, the trauma is betaine, niacinamide, adenosine, sodium hyaluronate, D-panthenol, tranexamic acid, Glycerin, butylene glycol, derivatives such as vitamin C, arbutin, and fructose-1,6-diphosphate trisodium salt It may include one or more selected from the group consisting of.

As an embodiment, the thickener included in the trauma is not limited and may be included as long as it is a water-soluble thickener that can be dissolved in the solvent. Specifically, the thickener may include one or more of a polyacrylate-based polymer and a natural thickener. For example, the polyacrylate-based polymer is carbomer, acrylate/C10-30 alkyl acrylate crosspolymer, ammonium acryloyldimethyl taurate/VP copolymer, hydroxyethyl acrylate/sodium acryloyldimethyl tau It may include at least one selected from the group consisting of a rate copolymer, sodium polyacrylate, and polyacrylate-13. Carbomer is not hydrophobic, so when it is included alone, stability is poor because it does not hold the oily component of the inner phase well, and polyacrylate polymers with other hydrophobic chains can hold the oily component well, but when it is included alone, it becomes fluffy. This can happen. Accordingly, an exemplary embodiment of the present invention may provide excellent dispersion and stability of oil-in-water droplets inside and outside by including a carbomer and a polyacrylate-based polymer having a hydrophobic chain as the thickener. As an example, the content ratio of the carbomer and the polyacrylate-based polymer may be 1: 0.5 to 1.5, more specifically about 1:1. As an example, the natural thickener may include a sugar thickener. As an embodiment, the natural thickener may include at least one selected from the group consisting of cellulose gum, hydropropyl methyl cellulose, xanthan gum, and Ceratonia Siliqua Gum, but is not limited thereto. As an example, the thickener may be included in an amount of 0.01 to 1.0% by weight, more specifically 0.05 to 0.5% by weight, based on the total weight of the composition. As an embodiment, the thickener may be included in an amount of 0.02 to 1.3% by weight, for example, 0.06 to 0.7% by weight, based on the total weight of the trauma.

As an example, the droplets including the inner and outer wounds included in the composition according to the present invention may be surfactant-free, which does not substantially contain a surfactant, and specifically, based on the total weight of the droplets It may contain a surfactant in an amount of 1% by weight or less, 0.1% by weight or less, or 0.01% by weight or less. As described above, the composition according to the present invention does not contain a surfactant in the droplets including the inner wound and the trauma, but instead includes a thickener, so that the multiple emulsifier type including the inner wound-trauma-outer phase can be stably maintained.

As an embodiment, the droplet may further include a neutralizing agent. For example, the neutralizing agent may include a salt, for example, sodium hydroxide, potassium hydroxide, L-arginine, triethanolamine, tromethamine, or a mixture thereof. Can include.

A droplet including an internal injury and a trauma according to an embodiment of the present invention; And in the multiple emulsion formulation including the outermost phase, the sum of the content of the interface of the outermost phase and the outermost phase may be more than 0% by weight to less than 20% by weight based on the total weight of the composition. Specifically, the sum of the content of the outermost phase and the interface of the outermost phase is 0.01% by weight or more, 0.05% by weight or more, 0.1% by weight or more, 0.2% by weight or more, 0.3% by weight or more, 0.4% by weight or more with respect to the total weight of the composition. , 0.5% or more, 0.6% or more, 0.7% or more, 0.8% or more, 0.9% or more, 1% or more, 2% or more, 3% or more, 4% or more, 5% or more , 6% or more, 7% or more, 8% or more, 9% or more, 10% or more, 11% or more, 12% or more, 13% or more, 14% or more, 15% or more , 16 wt% or more, 17 wt% or more, 18 wt% or more, or 19 wt% or more, and 19.9 wt% or less, 19 wt% or less, 18 wt% or less, 17 wt% or less, based on the total weight of the composition, 16% or less, 15% or less, 14% or less, 13% or less, 12% or less, 11% or less, 10% or less, 9% or less, 8% or less, 7% or less, 6 wt% or less, 5 wt% or less, 4 wt% or less, 3 wt% or less, 2 wt% or less, 1 wt% or less, 0.5 wt% or less, or 0.1 wt% or less.

In one embodiment, the silicone oil contained in the outermost phase is dimethicone, trimethicone, methyl trimethicone, phenyl trimethicone, amodimethicone, cyclomethicone, dimethiconol, vinyl dimethicone, propoxy Tetramethylpiperidinyl dimethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, methyl ether dimethyl silane, and at least one selected from the group consisting of copolymers thereof.

As an embodiment, the interface between the outermost wound and the trauma may include a silicone-based surfactant. Specifically, the silicone-based surfactant may have a hydrophile-lipophile balance (HLB) value of 7 or less. The HLB is based on Griffin's calculation method. More specifically, the silicone-based surfactant is a polyethylene glycol (PEG)-bonded silicone-based surfactant, and cyclopentasiloxane/dimethicone/dimethicone/PG-10/15 crosspolymer (CYCLOPENTASILOXANE/DIMETHICONE/DIMETHICONE/ PEG-10/15 CROSSPOLYMER) and cetyl PEG/PP-10/1 dimethicone/pentaerythrityl tetra-di-ti-butyl hydroxyhydrocinnamate (CETYL PEG/PPG-10/1 DIMETHICONE*PENTAERYTHRITYL TETRA- DI-T-BUTYL HYDROXYHYDROCINNAMATE) may include one or more. Or, as a silicone-based surfactant bound to polyglycerin, lauryl dimethicone/polyglycerin-3 copolymer (LAURYL DIMETHICONE/POLYGLYCERIN-3 CROSSPOLYMER), lauryl polyglyceryl-3 polydimethylsiloxyethyl dimethicone (LAURYL POLYGLYCERYL) -3 POLYDIMETHYLSILOXYETHYL DIMETHICONE), POLYGLYCERYL-3 POLYDIMETHYLSILOXYETHYL DIMETHICONE, Polyglyceryl-3 Disiloxane Dimethicone (POLYGLYCERYL-3 DISILOXANE Dimethicone/Polyglyceryl-Dimethicone) It may include one or more of 3 copolymers (DIMETHICONE/POLYGLYCERIN-3 CROSSPOLYMER). As an embodiment of the present invention, by including a silicone-based surfactant in the outermost phase, the distance between two adjacent droplets in the formulation of the present invention can be closely maintained to an average of 5 μm or less, and the multi-emulsified formulation of the internal wound-trauma-most external phase is stable. Can be maintained. As an example, the present invention can provide a multi-emulsified formulation of an inner wound-traumatic-outermost phase in which an average distance between two adjacent droplets in the above formulation is 5 μm or less, without including a thickening agent in the outermost phase. Accordingly, a thickener may be further included in the outermost phase by selection of a person skilled in the art. As an example, a formulation that does not contain a thickener in the outermost phase may provide a fresher feeling of use.

The method for preparing a multi-emulsified cosmetic composition of the present invention described above as an embodiment includes the steps of preparing droplets by introducing an inner wound into an outer box; And it may include the step of stabilizing by introducing the droplet to the outermost phase. More specifically, the manufacturing method is an oil-in-water droplet by adding and dispersing an external component including a polyol and a thickener into a solvent, and then introducing an oil component including oil into the external phase. ) To prepare a first emulsification step; And a second emulsification step of injecting and stabilizing the droplet into the outermost phase including the silicone oil and the silicone surfactant.

As an example, the first emulsification step may be performed by emulsifying a polymer without using a surfactant. As an example, the first emulsification step may be performed while stirring for 1 to 5 minutes at 2,000 to 4,000 rpm, for example. As an example, the first emulsification step includes, for example, adding the oil to the outer bed and then stirring at 2,000 to 5,000 rpm, for example, 3,000 to 4,000 rpm, for example, for 1 to 5 minutes. It can be.

As an example, the method may include adding an oily component in the first emulsification step and then performing polymer emulsification and then adding a neutralizing agent. As an embodiment, after the neutralizing agent is added, it may be stirred to prepare a stable droplet.

In addition, the second emulsification step may be performed by a high internal phase emulsion (HIPE) emulsification method. The present invention can improve stability in multiple emulsion formulations by lowering the freezing point of the inner wound by using the HIPE emulsification method.

As an example, the cosmetic composition according to the present invention may be a cosmetic composition for moisturizing skin.

An embodiment of the present invention may relate to the use of the above-described cosmetic composition as a cosmetic, and specifically, the cosmetic may be for skin moisturizing.

In addition, the cosmetic composition may preferably contain other ingredients that can give a synergistic effect to the main effect within a range that does not impair the main effect in addition to the ingredients. In addition to the active ingredient of the present invention, other ingredients may be appropriately selected and blended by those skilled in the art without difficulty depending on the formulation or purpose of use of other cosmetic compositions. In addition, as an example, the cosmetic composition of the present invention may include the above ingredients and other ingredients that are usually blended in the cosmetic composition as needed. For example, moisturizers, emollients, organic and inorganic pigments, organic powders, ultraviolet absorbers, preservatives, fungicides, antioxidants, plant extracts, pH adjusters, alcohols, pigments, fragrances, blood circulation accelerators, cooling agents, limiting agents, And purified water. Other compounding ingredients that may be included in the cosmetic composition of the present invention are not limited thereto, and the amount of the ingredients may be within a range not impairing the objects and effects of the present invention.

As an example, the formulation of the cosmetic composition is not particularly limited, and a formulation may be appropriately selected according to the purpose. For example, soft lotion (skin lotion and milk lotion), nourishing lotion, essence, nourishing cream, massage cream, makeup base, foundation, pack, essence, eye cream, eye essence, cleansing cream, cleansing foam, cleansing water, cleanser , Body lotion, body cream, body oil and body essence may be prepared in one or more formulations selected from the group consisting of, but is not limited thereto.

Hereinafter, the configuration and effects of the present invention will be described in more detail with reference to examples and drawings. However, the following examples and drawings are provided for illustrative purposes only to aid understanding of the present invention, and the scope and scope of the present invention are not limited thereto.

[Experimental Example 1]

As an embodiment of the present invention, a multi-emulsion cosmetic composition was prepared according to the following method with the composition of Table 1.

First, in Table 1 below, water-based moisturizer, ethanol, and thickener were added to purified water and dispersed, and then oil (emollient) was added to the outer phase, followed by stirring at 3600 rpm with a homomixer at room temperature for 3 minutes, and first emulsification. The phosphorus polymer was emulsified. Then, a neutralizing agent was added thereto to prepare internal and external particles having an average particle size of about 5 μm or less. Then, the prepared internal and external particles are slowly added to the outermost silicone-based surfactant and silicone oil, while the paddle is mixed, stirred with a homomixer, and a secondary emulsification of HIPE (high internal phase emulsion) is carried out, O/W/ The composition of the S emulsion formulation was prepared.

In the table below, the content of each component refers to a weight percent based on the total weight of the composition.

Example 1 solvent Purified water (D.I.WATER) TO 100 Moisturizer Glycerin (GLYCERINE) 13 Moisturizer Butylene Glycol (BUTYLENE GLYCOL) 7 solvent Ethanol (ETHANOL) 7 Thickener ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER 0.09 Thickener CARBOMER 0.09 Emollient SQUALANE 7 corrector TROMETHAMINE 0.09 Silicone surfactant Cyclopentasiloxane/Dimethicone/Dimethicone/PG-10/15 Crosspolymer (CYCLOPENTASILOXANE*DIMETHICONE*DIMETHICONE/PEG-10/15 CROSSPOLYMER) 3 Silicone surfactant Cetyl PEG/PPG-10/1 dimethicone/pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate (CETYL PEG/PPG-10/1 DIMETHICONE*PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE) 0.3 Silicone oil DIMETHICONE 10

The average value of the particle size of the droplets included in the prepared Example 1 was about 20 μm. 4 is an image obtained by using the microscope of Example 1 (Nikon, model name: Eclipse 80i Microscope). As shown in Figure 4, the cosmetic composition according to an embodiment of the present invention has a multi-emulsified formulation including an inner wound-a trauma-an outermost wound, and a structure adjacent to each other with a distance between the droplets including the inner wound and the trauma of 5 μm or less. It can be confirmed that it has.

[Experimental Example 2]

As an example, in order to confirm the difference in formulation stability according to the composition of droplets including internal and trauma contained in the composition of the present invention, the following experiment was conducted.

First, in Table 1 of [Experimental Example 1], only an aqueous part that can be frozen during freezing was separated, and the composition of ethanol and a moisturizing agent was adjusted as shown in Table 2 below to prepare a separate composition. And each prepared composition was stored frozen at -15 ℃ for 4 weeks. Each content in the table below refers to the total weight of the separated aqueous part as 100% by weight, and the content of each component is expressed in% by weight.

Example 2 Example 3 Example 4 Example 5 Example 6 Example 7 Example 8 Purified water (D.I.WATER) 89 87 85 80 77 75 73 Glycerin (GLYCERINE) One 3 5 10 13 13 13 Butylene Glycol (BUTYLENE GLYCOL) 7 7 7 7 7 7 7 Ethanol (ETHANOL) 3 3 3 3 3 5 7

As a result, as shown in FIG. 5, the higher the content of polyol and ethanol, the lower the freezing point, the more stable the formulation of the composition was, and thus became transparent. This means that when the composition of the multi-emulsified formulation of the present invention is prepared, the higher the content of polyol and ethanol in a certain range, the less swelling occurs in the internal and external droplets, so that the droplets are not broken and the formulation can be stably maintained.

[Experimental Example 3]

As an example, the following experiment was conducted to confirm the difference in formulation stability according to the average distance between adjacent droplets included in the composition of the present invention.

After preparing the droplet particles including the inner and outer wounds in the composition as in Example 1 of Table 1, respectively, 30% by weight, 50% by weight, 70% by weight, 80% by weight, 85% by weight, respectively, based on the total composition of the composition %, 90% by weight was added to the outermost part of the silicone-based surfactant and silicone oil to prepare a multi-emulsified cosmetic composition (Table 3).

Each prepared cosmetic composition was photographed with a microscope (Nikon, model name: Eclipse 80i Microscope), and the distance between two adjacent droplets appeared in each microscope image was analyzed, and the distance between the droplets was calculated by Equation 1.

[Equation 1]

Distance between droplets = (A)-(r+R)

In Equation 1, A is the distance between the centers of two adjacent droplets measured after 24 hours of preparation of the composition, and r and R are each radius of the two adjacent droplets measured on the same line as A.

In the table below, the content of each component refers to a weight percent based on the total weight of the composition.

Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Example 9 Example 10 Content of inner and trauma (% by weight) 30 50 70 80 85 90 Cyclopentasiloxane/Dimethicone/Dimethicone/PG-10/15 Crosspolymer (CYCLOPENTASILOXANE*DIMETHICONE*DIMETHICONE/PEG-10/15 CROSSPOLYMER) 3 3 3 3 3 3 CETYL PEG/PPG-10/1 DIMETHICONE*PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE 0.3 0.3 0.3 0.3 0.3 0.3 DIMETHICONE 66.7 46.7 26.7 16.7 11.7 6.7 Stability Immediately after manufacturing
Separated Produce
Immediately after
Separated Produce
Immediately after
Separated Separated stability stability Average value of the distance between two adjacent droplets (μm) More than 5μm More than 5μm More than 5μm More than 5μm 5μm or less 5μm or less Total sum of the area of droplets over the entire area of the microscope image (%) Less than 80% Less than 80% Less than 80% Less than 80% 80% or more 80% or more

6 is a microscope image of Comparative Example 2, FIG. 7 is Comparative Example 4, and FIG. 8 is a microscope image obtained by stirring and sampling the separated contents for microscopic photographing after preparation of Example 10, and the arrow line measures the distance between particles. It is a line drawn through the center of an adjacent droplet particle in order to do so. As a result, as shown in FIG. 9, in the case of formulations (Comparative Examples 1 to 3) in which the distance between adjacent droplets contained in the composition exceeds 5 μm and the total area of the droplets is less than 80% with respect to the total area, immediately after preparation A phase separation phenomenon occurred, and in the case of Comparative Example 4, a separation phenomenon was observed after 1 hour at 25°C. However, in the formulation (Example 10) in which the distance between adjacent droplets, which is an embodiment of the present invention, is 5 μm or less, phase separation does not occur, so that the formulation is stably maintained. The total sum of the areas of the droplets was calculated using the Image-Pro® 10 Image Analysis Software (Manufacturer: MEDIA CYBERNETICS) program. In the microscope image of Example 10, in order to calculate the total sum of the areas of the droplets with respect to the total area of the image, after converting the image to black and white, by applying a threshold, only a portion above a certain value, that is, an area other than the droplet, was extracted. The percentage of this area was calculated. 10 shows a part of the image outside the droplet as a blue area. The total pixels in the image file were 640 x 480 px ² =307200 px ² , and the measured value in the blue area was 35976 px ² (rounded to the fourth decimal point), which was 11.72% of the total area. From this, it can be seen that the total area of the droplets is 88.28% with respect to the total area of the microscope image of FIG. 10.

[Experimental Example 4]

As the feeling of use of an embodiment of the present invention, the feeling of oil and thickness was confirmed through sensory evaluation using the T-CATA (Temporal Check-All-That-Apply) technique.

As an example of the present invention, Example 1 was used. As a comparative example, a W/S emulsion composition (Comparative Example 5) having the composition of the following [Table 4] was prepared according to a commonly used manufacturing method.

In the table below, the content of each component refers to a weight percent based on the total weight of the composition.

Comparative Example 5 Purified water (WATER) To 100 Glycerin (GLYCERIN) 15 Sodium Chloride (SODIUM CHLORIDE) One Ethanol (ETHANOL) 7 Cyclopentasiloxane/Dimethicone/Dimethicone/PG-10/15 Crosspolymer (CYCLOPENTASILOXANE*DIMETHICONE*DIMETHICONE/PEG-10/15 CROSSPOLYMER) 3 DIMETHICONE 10 CETYL PEG/PPG-10/1 DIMETHICONE*PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE 0.3 Ethylhexylglycerin (ETHYLHEXYLGLYCERIN) 0.05

Oiliness evaluation

Six specialty skin care panels evaluated the oiliness of Example 1 and Comparative Example 5 by repeating it twice. A circle with a diameter of 5 cm was marked on the entire foil, and 50 µl of each composition was dispensed into the area and applied by rolling for 2 minutes using an index finger, and whether the property was recognized every 5 seconds for 120 seconds was evaluated. .

As a result, as shown in FIG. 11, in Comparative Example 5, the oily feeling continued to decrease during the evaluation time of 120 seconds, whereas in Example 1, oil-in-water particles exploded in 10 seconds upon application, and the oil contained in the innermost phase was The oily sensation increased as it touched, and the oily sensation did not decrease due to the oil even after 40 seconds. This means that the present invention provides high moisturizing power.

Thickness feeling evaluation

Six specialty skin care panels evaluated the thickness of Example 1 and Comparative Example 5 by repeating it twice. A circle with a diameter of 5 cm was marked on the entire foil, and 50 µl of each composition was dispensed into the area and applied by rolling for 2 minutes using an index finger, and whether the property was recognized every 5 seconds for 120 seconds was evaluated. .

As a result, as shown in FIG. 12, the thickness feeling of Comparative Example 5 rapidly decreased after application, whereas the feeling of thickness in Example 1 was maintained until 80 seconds during application, and the feeling of thickness was maintained higher than that of Comparative Example 5 even at 120 seconds. This means that the oil contained in the innermost phase of the composition according to an embodiment of the present invention provides a high moisturizing power in the present invention.

[Experimental Example 5]

As an example of the present invention, a multi-emulsified cosmetic composition containing thymol trimethoxy cinnamate (Melasolve ^TM , AMOREPACIFIC Co., Ltd.) as an active ingredient in the inner phase was prepared in the composition of Table 5. The manufacturing method is the same as in Experimental Example 1, except that the first emulsification temperature is a high temperature of 70°C.

In the table below, the content of each component refers to a weight percent based on the total weight of the composition.

Example 10 solvent Purified water (D.I.WATER) TO 100 Moisturizer Glycerin (GLYCERINE) 13 Moisturizer Butylene Glycol (BUTYLENE GLYCOL) 7 solvent Ethanol (ETHANOL) 7 Thickener Acrylate/C10-30 Alkyl Acrylate Crosspolymer 0.09 (ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER) Thickener CARBOMER 0.09 Emollient CAPRYLIC/CAPRIC TRIGLYCERIDE 4 Emollient Cetyl ethylhexanoate (CETYL ETHYLHEXANOATE) 3 Whitening main ingredient THYMOL TRIMETHOXYCINNAMATE 0.1 corrector TROMETHAMINE 0.09 Silicone surfactant Cyclopentasiloxane/Dimethicone/Dimethicone/PG-10/15 Crosspolymer (CYCLOPENTASILOXANE*DIMETHICONE*DIMETHICONE/PEG-10/15 CROSSPOLYMER) 3 Silicone surfactant Cetyl PEG/PPG-10/1 dimethicone/pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate (CETYL PEG/PPG-10/1 DIMETHICONE*PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE) 0.3 Silicone oil DIMETHICONE 10

A conventional O/W emulsion composition (Comparative Example 6) was prepared as a comparative example for confirming the improved formulation stability of Example 10 prepared above. The composition of the multi-emulsified (O/W/S) formulation of Example 10 and the general emulsified (W/S) formulation of Comparative Example 6 were stored for 12 weeks under severe conditions at 40° C., while the active ingredients contained in the inner phase of each formulation In Melasolve ^TM precipitation titer was confirmed. Table 6 below shows the weight% of Melasolve ^TM with respect to the initial Melasolve ^TM weight after 4 weeks, 8 weeks, 12 weeks, 16 weeks and 24 weeks of storage as an average value obtained through 3 replicate experiments. In the multi-emulsified (O/W/S) formulation of Example 10, since the weight% of Melasolve ^TM relative to the initial Melasolve ^TM weight was maintained close to 100% by weight, Melasolve ^TM did not precipitate and was stably included in the formulation. It can be confirmed that there is. The change in the weight% of Melasolve ^TM over time was caused by sample extraction and experimental deviation, and the actual content did not change.

4 weeks 8 weeks 12 weeks 16 weeks 24 weeks Example 10 (O/W/S) 95.80% by weight 98.60% by weight 99.20% by weight 98.90% by weight 99.10% by weight

Next, while storing the composition of the multi-emulsified (O/W/S) formulation of Example 10 and the general emulsified (O/W) formulation of Comparative Example 6 at a low temperature of -20°C, the efficacy contained in the inner phase of each formulation The component Melasolve ^TM precipitation titer was confirmed with a microscope (Nikon, model name: Eclipse 80i Microscope). The right image is the polarized image of the left image. As a result, in the general emulsified (O/W) formulation of Comparative Example 6, precipitation (arrow) of Melasolve ^TM was observed after 2 weeks of low temperature storage (Fig. 13), but the multi-emulsified (O/W/S) formulation of Example 10 In, Melasolve ^TM did not precipitate even after 4 weeks of low temperature storage (FIG. 14). This means that the multi-emulsifier type of the present invention can stably contain an effective substance such as Melasolve ^TM , which has a problem that precipitation is good due to low solubility.

The present invention can provide the following embodiments as an example.

A first embodiment includes: droplets including an inner wound and a trauma; And it is a multi-emulsified formulation comprising the outermost phase, and satisfying one or more of (i) to (iii), it is possible to provide a cosmetic composition:

(i) The distance between two adjacent droplets distributed in the formulation is 5 μm or less, the distance is calculated for droplets with an average particle size of 2 μm to 50 μm, and the distance between the droplets is calculated by Equation 1:

[Equation 1]

Distance between droplets = (A)-(r+R)

In Equation 1, A is the distance between the centers of two adjacent droplets of the composition, and r and R are the respective radii of the two adjacent droplets measured on the same line as A;

(ii) in the microscopic image of the composition, the sum of the areas of the droplets distributed in the formulation with respect to the total area of the image 100% is 80% or more and less than 100%, and the microscopic image is taken at a magnification of 1000; And

(iii) The content of the droplets including the inner and outer wounds is greater than 80% to less than 100% by weight based on the total weight of the composition.

In a second embodiment, in the first embodiment, the multiple emulsion formulation is an oily inner wound; Prime Minister Trauma; And it can provide a cosmetic composition comprising the outermost phase comprising a silicone-based oil.

In the third embodiment, in the first or second embodiment, the inner phase can provide a cosmetic composition comprising at least one of an ester oil, a hydrocarbon oil, a natural oil and a silicone oil. have.

In the fourth embodiment, in any one or more of the first to third embodiments, the inner phase is squalane, caprylic/capric triglyceride, cetyl ethylhexanoate. ), 2-Octyldodecanol (2-Octyldodecanol) and pentaerythritol terra-2-ethylhexanoate (Pentaerythritol Tetra-2-Ethylhexanoate) containing at least one oil selected from the group consisting of, to provide a cosmetic composition I can.

In a fifth embodiment, in any one or more of the first to fourth embodiments, the inner wound is made of thymol trimethoxycinnamate, an oil-soluble vitamin, a fat-soluble physiologically active ingredient, an oil-soluble licorice and polyphenol. It is possible to provide a cosmetic composition comprising at least one selected from the group consisting of.

A sixth embodiment can provide a cosmetic composition according to any one or more of the first to fifth embodiments, wherein the oil-soluble vitamin contains at least one of retinol and tocopherol.

The seventh embodiment can provide a cosmetic composition according to any one or more of the first to sixth embodiments, wherein the fat-soluble physiologically active component contains at least one of linolenic acid and glycolipid.

In an eighth embodiment, in any one or more of the first to seventh embodiments, the outer wound is polyol; Or a polyol, and at least one of a thickener and a solvent; containing, a cosmetic composition can be provided.

In the ninth embodiment, in any one or more of the first to eighth embodiments, the polyol is polyethylene glycol, polypropylene glycol, dipropylene glycol, propylene glycol, butylene glycol, glycerin, polyglycerin-3, One selected from the group consisting of propanediol, sorbitol, erythritol, xylitol, maltitol, ethylhexanediol, 1,2-hexanediol, sebum/sebum/polybutylene glycol-8/5/3 glycerin and pentylene glycol It is possible to provide a cosmetic composition comprising the above.

In a tenth embodiment, in any one or more of the first to ninth embodiments, the content of the polyol is 1% to 30% by weight based on the total weight of the composition; And, it is possible to provide a cosmetic composition satisfying at least one of 5% to 35% by weight based on the total weight of the trauma.

The eleventh embodiment can provide a cosmetic composition in any one or more of the first to tenth embodiments, wherein the solvent contains one or more of water and ethanol.

In a twelfth embodiment, in any one or more of the first to eleventh embodiments, the content of ethanol is 3% to 10% by weight based on the total weight of the composition; And it is possible to provide a cosmetic composition satisfying at least one of 5% to 12% by weight based on the total weight of the trauma.

In the thirteenth embodiment, in any one or more of the first to twelfth embodiments, the thickener can provide a cosmetic composition comprising at least one of a polyacrylate-based polymer and a natural thickener.

In a 14th embodiment, in any one or more of the first to 13th embodiments, the polyacrylate polymer is carbomer, acrylate/C10-30 alkyl acrylate crosspolymer, and ammonium acryloyldimethyltau. Rate/VP copolymer, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, sodium polyacrylate, and polyacrylate-13 comprising at least one selected from the group consisting of, to provide a cosmetic composition I can.

In a fifteenth embodiment, in any one or more of the first to fourteenth embodiments, the thickener can provide a cosmetic composition comprising a carbomer and a polyacrylate-based polymer having a hydrophobic chain.

The sixteenth embodiment provides a cosmetic composition according to any one or more of the first to fifteenth embodiments, wherein the weight ratio of the carbomer and the polyacrylate-based polymer having a hydrophobic chain is 1: 0.5 to 1.5. I can.

In the seventeenth embodiment, in any one or more of the first to sixteenth embodiments, the content of the thickener is 0.01 to 1.0% by weight based on the total weight of the composition; And it is possible to provide a cosmetic composition satisfying at least one of 0.02 to 1.3% by weight based on the total weight of the trauma.

In the eighteenth embodiment, in any one or more of the first to seventeenth embodiments, the silicone oil is dimethicone, trimethicone, methyl trimethicone, phenyl trimethicone, amodimethicone, cyclome At least one selected from the group consisting of chicon, dimethiconol, vinyl dimethicone, propoxytetramethylpiperidinyl dimethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, methyletherdimethylsilane, and copolymers thereof Containing, it is possible to provide a cosmetic composition.

The 19th embodiment can provide a cosmetic composition according to any one or more of the first to 18th embodiments, wherein the interface of the outermost image and the external image further comprises a silicone-based surfactant.

The twentieth embodiment can provide a cosmetic composition according to any one or more of the first to nineteenth embodiments, wherein the silicone-based surfactant is a silicone-based surfactant having a hydrophile-lipophile balance (HLB) value of 7 or less. .

In a twenty-first embodiment, in any one or more of the first to twenty embodiments, the silicone-based surfactant is cyclopentasiloxane/dimethicone/dimethicone/PG-10/15 crosspolymer (CYCLOPENTASILOXANE/DIMETHICONE/ DIMETHICONE/PEG-10/15 CROSSPOLYMER), Cetyl PEG/PPG-10/1 dimethicone/pentaerythrityl tetra-di-ti-butyl hydroxyhydrocinnamate (CETYL PEG/PPG-10/1 DIMETHICONE*PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE), lauryl dimethicone/polyglycerin-3 copolymer (LAURYL DIMETHICONE/POLYGLYCERIN-3 CROSSPOLYMER), lauryl polyglyceryl-3 polydimethylsiloxyethyl dimethicone (LAURYL POLYGLYCERYL-3) POLYDIMETHYLSILOXYETHYL DIMETHICONE), POLYGLYCERYL-3 POLYDIMETHYLSILOXYETHYL DIMETHICONE, Polyglyceryl-3 Disiloxane Dimethicone (POLYGLYCERYL-3 DISILOXANE DIMETHICONE) and Dimethicone-3 Dimethicone It is possible to provide a cosmetic composition comprising at least one selected from the group consisting of a combination (DIMETHICONE/POLYGLYCERIN-3 CROSSPOLYMER).

The 22nd embodiment can provide a cosmetic composition according to any one or more of the first to 21st embodiments according to claim 1, wherein the outermost phase does not contain a thickener.

The 23rd embodiment can provide a cosmetic composition according to any one or more of the first to 22nd embodiments, wherein the total content of the inner and outer wounds is 85% to 95% by weight based on the total weight of the composition. have.

The 24th embodiment can provide a cosmetic composition for moisturizing skin in any one or more of the first to 23rd embodiments.

The 25th embodiment can provide the use of the cosmetic composition according to any one or more of the first to 24th embodiments as a cosmetic product.

The twenty-sixth embodiment can provide the use of the twenty-fifth embodiment, wherein the cosmetic product is for skin moisturizing.

A twenty-seventh embodiment is a method for producing a cosmetic composition of any one or more of the first to twenty-fourth embodiments, comprising the steps of: injecting an inner wound into an outer wound to prepare droplets; And it is possible to provide a manufacturing method comprising the step of stabilizing by introducing the droplet to the outermost phase.

In a twenty-eighth embodiment, in the twenty-seventh embodiment, in the step of preparing the droplet, the trauma component including a polyol and a thickener is added and dispersed in a solvent, and then an oily component including oil is added to the trauma. Including the first emulsification step of producing oil-in-water droplets by input, a manufacturing method can be provided.

In the 29th embodiment, in any one or more of the 27th and 28th embodiments, the first emulsification step is performed at 2,000 to 5,000 rpm for 1 to 5 minutes after, for example, introducing the oil to the trauma It can provide a manufacturing method comprising stirring.

In a 30th embodiment, in any one or more of the 27th to 29th embodiments, the stabilizing step is a secondary emulsification step of introducing and stabilizing the droplet into the outermost phase containing a silicone oil and a silicone surfactant. It can provide a manufacturing method comprising a.

The 31st embodiment, in any one or more of the 27th to 30th embodiments, wherein the second emulsification step is performed by HIPE (high internal phase emulsion) emulsification method, it is possible to provide a manufacturing method. have.

Claims (31)

Droplets including internal and trauma; And a multi-emulsified formulation comprising the outermost phase, and satisfying at least one of (i) to (iii), a cosmetic composition:
(i) The distance between two adjacent droplets distributed in the formulation is 5 μm or less, the distance is calculated for droplets with an average particle size of 2 μm to 50 μm, and the distance between the droplets is calculated by Equation 1:
[Equation 1]
Distance between droplets = (A)-(r+R)
In Equation 1, A is the distance between the centers of two adjacent droplets of the composition, and r and R are the respective radii of the two adjacent droplets measured on the same line as A;
(ii) in the microscopic image of the composition, the sum of the areas of the droplets distributed in the formulation with respect to the total area of the image 100% is 80% or more and less than 100%, and the microscopic image is taken at a magnification of 1000; And
(iii) The content of the droplets including the inner and outer wounds is greater than 80% to less than 100% by weight based on the total weight of the composition. The method of claim 1, wherein the multiple emulsion formulation is
Inner injuries paid;
Prime Minister Trauma; And
Outermost phase containing silicone oil;
Containing, cosmetic composition. The cosmetic composition of claim 1, wherein the inner phase contains at least one of an ester oil, a hydrocarbon oil, a natural oil and a silicone oil. The method of claim 3, wherein the inner wound is squalane, caprylic/capric triglyceride, cetyl ethylhexanoate, 2-octyldodecanol, and pentaeryth. Lithol terra-2-ethylhexanoate (Pentaerythritol Tetra-2-Ethylhexanoate) comprising at least one oil selected from the group consisting of, a cosmetic composition. The cosmetic composition of claim 1, wherein the inner phase comprises at least one selected from the group consisting of thymol trimethoxycinnamate, oil-soluble vitamins, fat-soluble physiologically active ingredients, oil-soluble licorice and polyphenols. The cosmetic composition of claim 5, wherein the oil-soluble vitamin comprises at least one of retinol and tocopherol. The cosmetic composition of claim 5, wherein the fat-soluble physiologically active ingredient contains at least one of linolenic acid and glycolipid. The method of claim 1, wherein the trauma
Polyol; or
Polyol, and at least one of thickeners and solvents;
Containing, cosmetic composition. The method of claim 8, wherein the polyol is polyethylene glycol, polypropylene glycol, dipropylene glycol, propylene glycol, butylene glycol, glycerin, polyglycerin-3, propanediol, sorbitol, erythritol, xylitol, maltitol, ethylhexanediol, 1 , 2-hexanediol, sebum / sebum / polybutylene glycol-8/5/3 comprising at least one selected from the group consisting of glycerin and pentylene glycol, a cosmetic composition. According to claim 8, The content of the polyol is 1% to 30% by weight based on the total weight of the composition; And, satisfying at least one of 5% to 35% by weight based on the total weight of the trauma, cosmetic composition. The cosmetic composition of claim 8, wherein the solvent comprises at least one of water and ethanol. According to claim 11, The content of ethanol is 3% to 10% by weight based on the total weight of the composition; And satisfying at least one of 5% to 12% by weight based on the total weight of the trauma, cosmetic composition. The cosmetic composition of claim 8, wherein the thickener comprises at least one of a polyacrylate-based polymer and a natural thickener. The method of claim 13, wherein the polyacrylate polymer is carbomer, acrylate/C10-30 alkyl acrylate crosspolymer, ammonium acryloyldimethyltaurate/VP copolymer, hydroxyethyl acrylate/sodium acryloyl A cosmetic composition comprising at least one selected from the group consisting of dimethyl taurate copolymer, sodium polyacrylate, and polyacrylate-13. The cosmetic composition of claim 8, wherein the thickener comprises a carbomer and a polyacrylate-based polymer having a hydrophobic chain. The cosmetic composition of claim 15, wherein the weight ratio of the carbomer and the polyacrylate-based polymer having a hydrophobic chain is 1: 0.5 to 1.5. According to claim 8, The content of the thickener is 0.01 to 1.0% by weight based on the total weight of the composition; And satisfying at least one of 0.02 to 1.3% by weight based on the total weight of the trauma, cosmetic composition. The method of claim 2, wherein the silicone oil is dimethicone, trimethicone, methyltrimethicone, phenyltrimethicone, amodimethicone, cyclomethicone, dimethiconol, vinyldimethicone, propoxytetramethylpiperidi Neil dimethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, methyl ether dimethyl silane and a cosmetic composition comprising at least one selected from the group consisting of copolymers thereof. The cosmetic composition according to claim 2, wherein the interface of the outermost wound and the external wound further comprises a silicone-based surfactant. The cosmetic composition of claim 19, wherein the silicone-based surfactant is a silicone-based surfactant having a hydrophile-lipophile balance (HLB) value of 7 or less. The method of claim 19, wherein the silicone surfactant is cyclopentasiloxane/dimethicone/dimethicone/PG-10/15 crosspolymer (CYCLOPENTASILOXANE/DIMETHICONE/DIMETHICONE/PEG-10/15 CROSSPOLYMER), cetyl PEG/PPG -10/1 dimethicone/pentaerythrityl tetra-di-ti-butyl hydroxyhydrocinamate (CETYL PEG/PPG-10/1 DIMETHICONE*PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE), lauryl dimethicone/poly Glycerin-3 copolymer (LAURYL DIMETHICONE/POLYGLYCERIN-3 CROSSPOLYMER), lauryl polyglyceryl-3 polydimethylsiloxyethyl dimethicone (LAURYL POLYGLYCERYL-3 POLYDIMETHYLSILOXYETHYL DIMETHICONE), polyglyceryl-3 polydimethylsiloxyethyl dime Chicon (POLYGLYCERYL-3 POLYDIMETHYLSILOXYETHYL DIMETHICONE), polyglyceryl-3 disiloxane dimethicone (POLYGLYCERYL-3 DISILOXANE DIMETHICONE) and dimethicone/polyglycerin-3 copolymer (one or more selected from the group consisting of DIMETHICONE/POLYGLYCERIN-3 CROSSPOLYMER) Containing, cosmetic composition. The cosmetic composition according to claim 1, wherein the outermost wound does not contain a thickener. The cosmetic composition of claim 1, wherein the total content of the inner and outer wounds is 85% to 95% by weight based on the total weight of the composition. The cosmetic composition according to claim 1, which is for moisturizing skin. Use of the cosmetic composition according to claim 1 as a cosmetic product. The use of claim 25, wherein the cosmetic is for moisturizing the skin. A method for preparing the cosmetic composition of any one of claims 1 to 24,
Injecting the inner wound to the trauma to prepare a droplet; And
Including the step of stabilizing by introducing the droplet to the outermost phase, a manufacturing method. The method of claim 27, wherein the step of preparing the droplet,
The first emulsification step of preparing an oil-in-water droplet by adding and dispersing an external component including polyol and a thickener into a solvent, and then introducing an oil component including oil into the external phase. Containing, manufacturing method. The method of claim 28, wherein the first emulsification step comprises, for example, adding the oil to the trauma and then stirring at 2,000 to 5,000 rpm for 1 to 5 minutes. The method of claim 27, wherein the stabilizing step
A method comprising a second emulsification step of stabilizing and adding the droplet to the outermost phase comprising a silicone-based oil and a silicone-based surfactant. The method of claim 30, wherein the second emulsification step is performed by a high internal phase emulsion (HIPE) emulsification method.

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