KR20210012570A - Medical education system of observing structure, function and transform of vessel with implantable sensor and its way to working - Google Patents

Abstract

The present invention relates to a medical education system which can observe a structure, a function, and a mutation of a blood vessel through an implantable bio-signal and a driving method thereof. The medical education system which can observe a structure, a function, and a mutation of a blood vessel through an implantable bio-signal comprises a bio-signal sensor unit, a wireless communication unit, a database server, and a smart device. Accordingly, by attaching the bio-signal sensor to various locations in a body, changes in the blood vessel in accordance with the attached locations can also be observed.

Description

A medical education system capable of observing the structure, function, and mutation of blood vessels through an implantable biological signal sensor and its driving method {MEDICAL EDUCATION SYSTEM OF OBSERVING STRUCTURE, FUNCTION AND TRANSFORM OF VESSEL WITH IMPLANTABLE SENSOR AND ITS WAY TO WORKING}

The present invention relates to a medical education system capable of observing the structure, function, and mutation of blood vessels, and a driving method thereof, and more specifically, a system for medical education capable of observing the structure, function and mutation of blood vessels through an implantable biological signal sensor, and the same It relates to the driving method.

Cardiovascular diseases such as angina pectoris and myocardial infarction are the leading causes of adult mortality in Korea as well as in developed countries, and the prevalence rate is increasing rapidly. 1 is a view showing the trend of increasing medical expenses and salary expenses related to cardiovascular diseases in Korea. As shown in Fig. 1, according to health insurance statistics in 2014, the medical insurance benefit cost related to cardiovascular disease in Korea was about 5,320 billion won, which is more than 5 times higher than about 1.1 trillion won in 2004, and an annual average increase of 17.3%. The rapid increase rate of the prevalence can be seen in that it shows

As the incidence of cardiovascular diseases such as arteriosclerosis as described above increases and social attention is drawn, interest in research and education on the blood vessel itself such as the function or structure of blood vessels is also increasing. However, since conventional medical education systems are based on information recorded and stored in the past, they cannot provide real-time information on blood vessels, and because they are based on limited data, they can only provide theoretical knowledge. It was far from providing user interest. Therefore, there is a need for a medical education system that can provide not only theoretical knowledge but also information about blood vessels in real time, and considers users' interests.

Meanwhile, as a prior art related to the present invention, Korean Patent Registration No. 10-1827087 (name of the invention: big data-based biosignal analysis system and method, announcement date: February 08, 2018) has been disclosed.

The present invention has been proposed to solve the above problems of the previously proposed methods, and by using data received from a biosignal sensor that can be implanted in the body, not only theoretical knowledge about blood vessels, but also the structure of blood vessels, Biometric information of functions and mutations, blood pressure and body temperature can be provided together in real time, it can help to learn human anatomy knowledge, and by providing real-time images of blood vessel conditions to users, it induces user interest. Thus, it is an object of the present invention to provide a medical education system capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor that can induce more active use of a medical education system.

In addition, according to the present invention, by attaching an implantable biosignal sensor not only to a subject for measuring a biosignal, but also to a body or an experimental animal, various and rich databases for learning about blood vessels can be constructed, and a single biosignal sensor can be implanted for a long time. It is possible to accurately and continuously observe blood vessel conditions such as blood pressure of the user's blood vessel during the period, and by attaching the biosignal sensor to various locations in the body, the change of blood vessels according to the attached location can also be observed. Another object is to provide a system for medical education in which blood vessel structure, function and mutation can be observed through.

A medical education system capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to a feature of the present invention for achieving the above object,

As a medical education system that can observe the structure, function and mutation of blood vessels through an implantable biosignal sensor,

A biological signal sensor unit mounted on a blood vessel in the body to observe biometric information including a structure, function, and variation of the blood vessel, and measure and calculate biometric information including a blood flow amount, a blood flow rate, a blood pressure, and a body temperature;

A wireless communication unit for wirelessly transmitting the biometric information observed, measured, and calculated by the biometric signal sensor unit;

A database server for collecting and storing the biometric information received from the wireless communication unit; And

It is characterized in that it comprises a smart device that processes the biometric information collected and stored in the database server and displays it through an application for medical education.

Preferably, the biometric signal sensor unit,

It may be mounted on a blood vessel in the body of a subject, a human body, or an animal.

More preferably, the biometric signal sensor unit,

Can be attached to one of the blood vessels in the body arteries.

Preferably, the biometric signal sensor unit,

A capacitive sensor for observing the structure, function, and variation of a blood vessel equipped with the bio-signal sensor unit, and measuring a passed blood flow rate and a blood flow rate;

A temperature sensor measuring body temperature at a location where the biometric signal sensor unit is mounted; And

The capacitive sensor and the temperature sensor collect data observed and measured in real time, and may include a calculation module that calculates blood pressure using blood flow and blood flow velocity data among the collected data.

More preferably, the capacitive sensor,

A measurement capacitive sensor, which observes the structure, function, and variation of blood vessels, and measures the amount of blood flow passed and the blood flow rate; And

The measurement capacitive sensor may include a reference capacitive sensor, which is a reference for observing the structure, function, and variation of blood vessels, and measuring the amount of blood flow passed through and the blood flow rate.

Even more preferably, the capacitive sensor,

It is made of a flexible material, and may be a ring-shaped sensor surrounding the blood vessel in accordance with the cylindrical shape of the blood vessel on which the capacitive sensor is mounted.

Even more preferably, the capacitive sensor,

It is designed to sense the blood vessel wall existing between the blood as a measurement target material and the capacitive sensor, and may be a sensor optimized for mounting the vessel wall using finite element analysis.

More preferably, the temperature sensor,

It may be a digital temperature sensor using a Monolithic CMOS IC in which the processing, correction, and interface of the measured signal are integrated.

Preferably, the smart device,

Real-time biometric information collected in the database server and biometric information previously stored in the database server and converted into a database for learning may be processed through a compensation algorithm, and displayed individually or simultaneously through an application for vascular medicine education.

Preferably,

It may be configured to further include a power supply that provides power to the bio-signal sensor unit and the wireless communication unit and is charged wirelessly.

In order to achieve the above object, a method of driving a medical education system capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to a feature of the present invention,

As a driving method of a medical education system capable of observing blood vessel structure, function and mutation through an implantable biosignal sensor

(1) observing the biometric information including the structure, function, and mutation of the blood vessel by a biometric signal sensor mounted on the blood vessel in the body, and measuring biometric information including blood flow, blood flow rate, blood pressure, and body temperature;

(2) wirelessly transmitting the biometric information observed, measured and calculated in step (1) from a wireless communication unit;

(3) collecting and storing the biometric information received in step (2) in a database server; And

(4) processing the biometric information collected and stored in step (3), and displaying it through an application for medical education.

Preferably, in step (1),

The biometric signal sensor unit may be mounted on a blood vessel within the body of a person, a body of a person, or an animal.

More preferably, in the step (1),

The biosignal sensor unit may be mounted on an artery among blood vessels in the body.

Preferably, the step (1),

(1-1) observing the structure, function, and variation of the blood vessel on which the bio-signal sensor unit is mounted with a capacitive sensor, and measuring the amount of blood flow and the blood flow rate through the capacitive sensor;

(1-2) measuring a body temperature at a location where the bio-signal sensor unit is mounted using a temperature sensor; And

(1-3) collecting data measured in real time in steps (1-1) and (1-2), but calculating blood pressure using blood flow and blood flow velocity data among the collected data. Can be implemented.

More preferably, the capacitive sensor,

A measurement capacitive sensor, which observes the structure, function, and variation of blood vessels, and measures the amount of blood flow passed and the blood flow rate; And

The measurement capacitive sensor may include a reference capacitive sensor, which is a reference for observing the structure, function, and variation of blood vessels, and measuring the amount of blood flow passed through and the blood flow rate.

Even more preferably, the capacitive sensor,

It is made of a flexible material, and may be a ring-shaped sensor surrounding the blood vessel in accordance with the cylindrical shape of the blood vessel on which the capacitive sensor is mounted.

Even more preferably, the capacitive sensor,

It is designed to sense the blood vessel wall existing between the blood as a measurement target material and the capacitive sensor, and may be a sensor optimized for mounting the vessel wall using finite element analysis.

More preferably, the temperature sensor,

It may be a digital temperature sensor using a Monolithic CMOS IC in which the processing, correction, and interface of the measured signal are integrated.

Preferably, in step (4),

Real-time biometric information collected in step (3) and biometric information previously stored in step (3) and converted into a database for learning may be processed through a compensation algorithm, and displayed individually or simultaneously through an application for vascular medicine education.

Preferably,

(5) The step (1) and step (2) may be implemented by providing power and charging wirelessly.

According to the medical education system capable of observing the structure, function, and mutation of blood vessels through the implantable biosignal sensor proposed in the present invention, theoretical knowledge about blood vessels by using data received from the biosignal sensor that can be implanted in the body In addition, it can provide biometric information of blood vessel structure, function and mutation, blood pressure, and body temperature together in real time, helps to learn human anatomy knowledge, and provides real-time images of blood vessel status to users. By doing so, it is possible to induce the user's interest and induce more active use of the medical education system.

In addition, according to the medical education system capable of observing the structure, function, and mutation of blood vessels through the implantable biosignal sensor proposed in the present invention, the implantable biosignal sensor is mounted not only to the subject of biosignal measurement, but also to the body or laboratory animal. , It is possible to build a diverse and rich learning database for blood vessels, and it is possible to accurately and continuously observe the blood vessel state such as blood pressure of the user's blood vessel for a long time even with a single biosignal sensor implantation. By attaching to the position, it is possible to observe changes in blood vessels according to the attached position.

1 is a view showing the trend of increasing domestic cardiovascular disease-related medical expenses and salary expenses.
2 is a diagram showing a configuration of a medical education system capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention as a functional block.
3 is a diagram showing a predicted form of a medical education system capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention.
4 is a diagram showing a configuration of a biosignal sensor unit of a medical education system capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention as a functional block.
5 is a diagram showing the configuration of a system capacitive sensor for medical education capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention as a functional block.
FIG. 6 is a diagram showing a variation of a blood vessel detected by a capacitive sensor of a medical education system capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention.
7 is a diagram showing a circuit conceptual diagram of a system capacitive sensor for medical education capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention.
8 is a schematic perspective view of a medical education system capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention.
9 is a calculation by separating the capacitive components of arterial wall permittivity and blood permittivity in a capacitive sensor of a medical education system capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention. A diagram showing the principle of doing.
10 is a diagram illustrating a simulation method for optimizing a capacitive sensor of a medical education system capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention using finite element analysis. .
11 is a diagram showing a conceptual diagram of an in vitro experiment for confirming the performance of a system capacitive sensor for medical education capable of observing a blood vessel structure, function, and mutation through an implantable biological signal sensor according to an embodiment of the present invention.
12 is a view showing a display screen of a medical education system smart device capable of observing a blood vessel structure, function, and mutation through an implantable bio-signal sensor according to an embodiment of the present invention.
13 is a diagram illustrating a flow of a method for driving a medical education system capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention.
14 is a diagram illustrating a flow of a method of driving a biosignal sensor unit for a medical education system capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention.

Hereinafter, preferred embodiments will be described in detail with reference to the accompanying drawings so that those of ordinary skill in the art may easily implement the present invention. However, in describing a preferred embodiment of the present invention in detail, if it is determined that a detailed description of a related known function or configuration may unnecessarily obscure the subject matter of the present invention, the detailed description thereof will be omitted. In addition, the same reference numerals are used throughout the drawings for portions having similar functions and functions.

In addition, throughout the specification, when a part is said to be connected to another part, this includes not only the case that it is directly connected, but also the case that it is indirectly connected with another element interposed therebetween. In addition, the inclusion of certain components means that other components may be further included rather than excluding other components unless specifically stated to the contrary.

2 is a diagram showing a configuration of a medical education system 10 capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention as a functional block, and FIG. 3 is A diagram showing a predicted form of a medical education system 10 capable of observing a blood vessel structure, function, and mutation through an implantable biological signal sensor according to an embodiment. 2 to 3, the medical education system 10 capable of observing the structure, function, and mutation of blood vessels through an implantable biosignal sensor according to an embodiment of the present invention is mounted on a blood vessel in the body In the biosignal sensor unit 100, which observes biometric information including structure, function, and mutation, and measures and calculates biometric information including blood flow, blood flow rate, blood pressure, and body temperature, The wireless communication unit 200 for wirelessly transmitting the observed, measured and calculated biometric information, the database server 300 for collecting and storing the biometric information received from the wireless communication unit 200, and the data collected and stored in the database server 300 It may be configured to include a smart device 400 that processes biometric information and displays it through a medical education application.

The biosignal sensor unit 100 is a sensor that is implanted in the body to measure and calculate biometric information, and not only a person to measure biometric information equipped with the biometric signal sensor unit 100 to measure biometric information, but also a human body, or Mounting can also be mounted on blood vessels in the animal's body. Therefore, not only can the user's own biometric information be accumulated or observed in real time, but also various biometric information measured from the biometric information sensor unit 100 mounted on the body of another user, a human body, or an experimental animal, the database server 300 It can be collected and stored in, and through this, a more accurate and professional learning database can be built from vast amounts of biometric information.

The biosignal sensor unit 100 may be mounted on a blood vessel in the user's body to observe biometric information including a structure, function, and mutation of the blood vessel, and measure a biosignal including blood pressure, blood flow, and body temperature. Blood pressure refers to the pressure exerted on the walls of blood vessels when blood is flowing through the blood vessels. Depending on the name of the blood vessel, it can be classified as arterial blood pressure, capillary blood pressure, and venous blood pressure, and usually blood pressure often means arterial blood pressure. In the case of the present invention, the physiological signal sensor unit 100 may be mounted on an artery among blood vessels in the user's body to measure a physiological signal such as blood pressure in the artery.

FIG. 4 is a diagram showing a configuration of a biosignal sensor unit 100 of a medical education system capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention as a functional block. As shown in FIG. 4, the biosignal sensor unit 100 of a medical education system capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention includes a biosignal sensor unit ( 100) observes the structure, function, and variation of the installed blood vessel, and measures the body temperature at the location where the biosignal sensor unit 100 is mounted, and the capacitive sensor 110 measures the amount of blood flow and the blood flow rate passed through. The temperature sensor 120, the capacitive sensor 110, and the temperature sensor 120 collects data measured in real time, but calculates blood pressure using blood flow and blood flow velocity data among the collected data. ) Can be included.

5 is a diagram showing a configuration of a medical education system capacitive sensor 110 capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention as a functional block. As shown in FIG. 5, the system capacitive sensor 110 for medical education capable of observing the structure, function and mutation of blood vessels through the implantable biosignal sensor according to an embodiment of the present invention includes the structure, function, and And observing the mutation, observing the structure, function, and mutation of the blood vessel in the measurement capacitive sensor 111, which measures the amount of blood flow passed through and the blood flow rate, and is a reference for measuring the amount of blood flow and the blood flow rate passed through. It may be configured to include a reference capacitive sensor 112. Hereinafter, the principle, configuration and arrangement of the capacitive sensor 110 will be described in detail.

When there is a dielectric between the two electrode plates, a capacitor is formed regardless of the shape or size of the conductor. When a DC voltage source is connected to the two electrode plates, the surface of the two electrode plates connected to the positive and negative power terminals Positive and negative charges accumulate. Capacitance of a capacitor made of two poles is defined as the value obtained by dividing the total amount of charge of an object by the voltage of the object. Dielectric constant is the physical effect that the medium between the charges has on the electric field when an electric field acts between them. It is a unit, and it can also be viewed as the amount of charge a medium can store. At this time, even with the same amount of material, if the dielectric constant is higher, more charges can be stored, so that the capacitance increases. The capacitive sensor 110 may measure the amount of liquid using static electricity in a container in which the liquid flows. More specifically, when the amount of blood flow changes, the portion occupied by air and the portion occupied by blood flow in the capacitor area Blood flow can be measured through the change in dielectric constant that occurs according to the ratio of. That is, the amount of blood flow may be calculated through Equation 1 below according to the capacitance value measured through the electrode of the capacitive sensor 110.

In addition, by designing the capacitive sensor 110 as a blood flow measurement sensor and a blood flow velocity measurement sensor, both the blood flow through the blood vessel and the blood flow velocity through the capacitive sensor 110 can be measured.

6 is a diagram showing a shape of a blood vessel mutation detected by the capacitive sensor 110 of a medical education system capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention. . As shown in FIG. 6, the blood vessels have a variety of variations, and according to the location of the vessel on which the capacitive sensor 110 is mounted, the structure of the vessel, such as the diameter of the vessel and the thickness of the vessel wall, and the variation of the vessel are observed. Can be measured.

7 is a diagram illustrating a circuit conceptual diagram of a system capacitive sensor 110 for medical education capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention. As shown in FIG. 7, the capacitive sensor 110 of the medical education system capable of observing the structure, function, and mutation of blood vessels through the implantable biosignal sensor according to an embodiment of the present invention includes an MCU and an MCU through a MUX. The connected and collected data may be signal-processed through an analog comparator. The measurement capacitive sensor 111 and the reference capacitive sensor 112 constituting the capacitive sensor 110 are attached to and installed on the vessel wall, and may be spaced apart from each other to prevent electric field interference.

8 is a schematic perspective view of a medical education system capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention. As shown in FIG. 8, the capacitive sensor 110 of the medical education system capable of observing the structure, function, and mutation of blood vessels through the implantable biosignal sensor according to an embodiment of the present invention is made of a flexible material. Consisting of, it may be a sensor in the form of a ring surrounding the blood vessel according to the cylindrical shape of the blood vessel on which the capacitive sensor 110 is mounted. That is, since the artery is in a cylindrical shape, the capacitive sensor should also be designed in an annular shape. Since most capacitive sensors are made of a flat plate, in the present invention, the capacitive of the flat plate can be approached in an annular shape In order to be able to derive the equation 2 below, the mathematical model of the annular capacitive sensor 110 may be completed by using this.

9 shows the capacitive components of arterial wall permittivity and blood permittivity in the capacitive sensor 110 of a medical education system capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention. It is a diagram showing the principle of separating calculation, and FIG. 10 illustrates a capacitive sensor 110 of a medical education system capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention. A diagram showing a simulation method optimized using finite element analysis. 9 to 10, a capacitive sensor 110 of a medical education system capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention is a measurement object It is designed to sense the blood vessel wall existing between the user's blood as a substance and the capacitive sensor 110, and may be a sensor optimized for mounting the vessel wall using finite element analysis.

More specifically, a general capacitive sensor directly contacts the measurement material, but in the present invention, since the capacitive sensor 110 is located above the arterial blood vessel, there is an arterial wall between the blood flow and the capacitive sensor 110. , As shown in FIG. 9, two capacitive components, the dielectric constant 2 of the inner wall of the artery and the dielectric constant 1 of the blood, can be separated and identified. That is, assuming that there is an artery between 1 of the blood to be measured and the capacitive sensor 110, it can be applied to the present invention through Equation 3 below. Here, in the case of Equation 3, in order to avoid the end effect, the electrode thickness of the capacitive sensor 110 is 0, has an infinite conductivity, and can be obtained by assuming that the length of the electrode is greater than the width. You can find the C value between the two electrolytes.

As shown in FIG. 10, using the derived Equation 3 and the 2D computational model of FIG. 9, the appearance of the capacitive sensor 110 attached outside the blood vessel in COMSOL software can be designed through finite element modeling. In addition, through this, the capacitive sensor 110 can be optimized.

In addition, the capacitive sensor 110 may measure foreign substances present in the user's blood. More specifically, the capacitive sensor 110 may measure a foreign substance in the user's blood by detecting a change in dielectric constant according to a foreign substance present in the user's blood.

FIG. 11 is a diagram showing a conceptual diagram of an in vitro experiment for confirming the performance of a medical education system capacitive sensor 110 capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention to be. As shown in FIG. 11, the capacitive sensor 110 of the system for real-time monitoring of intra-body blood vessel implantation type biometric information according to an embodiment of the present invention may test blood pressure measurement performance through an in-vitro in vitro experiment. . More specifically, performance can be checked using the aorta of the body. After connecting one liquid container to each end of the blood vessel, a process in which blood flow from the blood vessel is littered in one direction is simulated using a peristaltic pump. At this time, after the sensor is fixed outside the blood vessel and connected to an ICR (Inductance, Capacitive, Resistance) meter that can measure the capacitance value, the change in the capacitance value can be observed while controlling the pump's export pressure.

The temperature sensor 120 may be a digital temperature sensor using a monolithic CMOS IC in which processing, correction, and interface of a measured signal are integrated. More specifically, the temperature sensor 120 may use a Monolithic CMOS IC in which processing, correction, and interface of the measured signal are integrated, and the microcontroller for driving the system is a 32-bit energy-efficient ARM Cortex M3 architecture. By using the microcontroller EFM32, it is possible to ensure operation at a low current and ensure a longer period of use in the body.

The calculation module 130 may collect data measured in real time from the capacitive sensor 110 and the temperature sensor 120, and use the user's blood flow and blood flow velocity data among the collected data to determine the user's blood pressure. Can be calculated. That is, the calculation module 130 may be a microcontroller unit (MCU) that performs a function by making a microprocessor and an input/output module into one chip, and is received from the capacitive sensor 110 and the temperature sensor 120. Data is passed to the MCU. The MCU can analyze and process data through an algorithm designed inside, and in particular, it can calculate the user's blood pressure using blood flow and blood flow velocity data.

The wireless communication unit 200 may wirelessly transmit the user's biometric information measured and calculated by the biometric signal sensor unit 100 to the database server 300. That is, a circuit may be manufactured so that all data measured by the in vivo biosignal sensor unit 100 is transmitted to the outside of the database server 300 using a wireless communication method such as Bluetooth.

The database server 300 may collect and store the user's biometric information received from the wireless communication unit 200. That is, in order to develop a more specialized medical education system 10, it is important to build a database server 300 that holds a vast amount of data. In the case of the present invention, a person who measures biometric information to observe the user's own biometric information In addition, a large amount of biometric information can be collected and stored in the database server 300 by attaching the biosignal sensor unit 100 to a human body or blood vessel in the body of an animal, through which a large amount of data can be more accurate and specialized. You can build a classic learning database.

12 is a diagram illustrating a display screen of a medical education system smart device 400 capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention. As shown in FIG. 12, a medical education system smart device 400 capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention is collected in the database server 300 and The stored biometric information can be processed and displayed through a medical education application. The medical education application can be developed to help learn blood vessel knowledge of animals and humans based on the data obtained from the biometric signal sensor unit 100, which can be implemented using an Android Studio development environment. That is, through a medical education application, not only real-time biometric information data such as the structure, function, and mutation of blood vessels observed and measured by the biosignal sensor unit 100, passed blood flow, blood flow rate, and body temperature, but also a database server Learning data accumulated and stored in 300 can also be displayed individually or at the same time, and through this, it is possible to easily obtain knowledge about blood vessels and help users to easily access anatomy studies.

In particular, biometric information data obtained from a human body or laboratory animal may require correction. In the case of the present invention, an algorithm for compensating the value measured by the biosignal sensor unit 100 by applying Curve Fitting to the collected data By developing, it is possible to provide more accurately processed data to users.

The medical education system 10 capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention provides power to the biosignal sensor unit 100 and the wireless communication unit 200, and , It may be configured to further include a power supply 500 that is charged wirelessly. That is, by allowing the power supply unit 500 to be wirelessly charged, the user can live daily life for a long time even after implanting the present invention in the body, and the use and management of the device inserted into the body can be made more convenient.

The medical education system 10 capable of observing the structure, function, and mutation of blood vessels through an implantable biosignal sensor according to an embodiment of the present invention can check its performance through animal experiments. More specifically, after attaching the sensor to the artery of the mouse and fixing the implantable device to the stomach of the mouse, the animal is saved again, and the measured data is wirelessly collected in the database server 300. Medical education system capable of observing blood vessel structure, function and mutation through the implantable biosignal sensor according to an embodiment of the present invention by transmitting the collected data to the smart device 400 and displaying it through the established medical education application You can check the performance of (10).

13 is a diagram showing a flow of a driving method of a medical education system 10 capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention, and FIG. 14 is an exemplary embodiment of the present invention. A diagram showing a flow of a method of driving the system for medical education bio-signal sensor unit 100 capable of observing a blood vessel structure, function, and mutation through an implantable bio-signal sensor according to an embodiment. 13 to 14, the method of driving the medical education system 10 capable of observing the structure, function, and mutation of blood vessels through an implantable biosignal sensor according to an embodiment of the present invention is mounted on a blood vessel in the body. The biosignal sensor unit 100 observes biometric information including the structure, function, and variation of blood vessels, and measures and calculates biometric information including blood pressure and body temperature (S100), and observation and measurement at step S100 And wirelessly transmitting the calculated biometric information from the wireless communication unit 200 (S200), collecting and storing the biometric information received at the step S200 in the database server 300 (S300), and collecting and storing the biometric information at the step S300 It may be implemented including a step (S400) of processing the stored biometric information and displaying it through an application for medical education, and step S100 observes the structure, function, and mutation of the blood vessel on which the biosignal sensor unit 100 is mounted. And, the step of measuring the passed blood flow and the blood flow rate by the capacitive sensor 110 (S110), the step of measuring the body temperature of the bio-signal sensor unit 100 is mounted in the temperature sensor 120 (S120) , And collecting the data measured in real time in steps S110 and S120, and calculating the user's blood pressure by using the user's blood flow and blood flow rate data among the collected data (S130).

Details related to each step have been sufficiently described with respect to the medical education system 10 capable of observing the structure, function, and mutation of blood vessels through the implantable biosignal sensor according to an embodiment of the present invention. Is omitted.

As described above, according to a medical education system capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor according to an embodiment of the present invention, by using data received from a biosignal sensor that can be implanted in the body, It can provide not only theoretical knowledge about blood vessels, but also biological information such as structure, function, and mutation, blood pressure, and body temperature of blood vessels in real time, and can help learn human anatomy knowledge, and provide real-time information to users. By providing an image on the state of blood vessels together, it is possible to induce interest of the user and induce more active use of the medical education system. In addition, by attaching an implantable biosignal sensor to not only the subject of biosignal measurement, but also to the body or laboratory animal, various and rich databases for learning about blood vessels can be built. It is possible to accurately and continuously observe the state of blood vessels such as blood pressure, and by attaching the biosignal sensor to various locations in the body, it is possible to observe changes in blood vessels according to the attached location.

The present invention described above can be modified or applied in various ways by those of ordinary skill in the technical field to which the present invention belongs, and the scope of the technical idea according to the present invention should be determined by the following claims.

10: Medical education system capable of observing blood vessel structure, function and mutation
100: biosignal sensor unit
110: capacitive sensor
111: measuring capacitive sensor
112: reference capacitive sensor
120: temperature sensor
130: arithmetic module
200: Ministry of Wireless Communication
300: database server
400: smart device
500: power supply
S100: Step of observing the biometric information of the structure, function, and mutation of the blood vessel by a biometric signal sensor mounted on the blood vessel in the body, and measuring and calculating the biometric information of blood pressure and body temperature
S110: Observing the structure, function, and mutation of the blood vessel equipped with the biosignal sensor unit, and measuring the amount of blood flow and the blood flow rate passed through the capacitive sensor.
S120: Step of measuring the body temperature at the location where the biometric signal sensor unit is mounted using the temperature sensor
S130: Collecting data measured in real time in steps S110 and S120, but calculating blood pressure using blood flow and blood flow rate data among the collected data.
S200: wirelessly transmitting biometric information observed, measured and calculated in step S100
S300: collecting and storing the biometric information received in step S200 in a database server
S400: processing the biometric information collected and stored in step S300, and displaying it through an application for medical education

Claims (20)

As a medical education system 10 capable of observing the structure, function, and mutation of blood vessels through an implantable biosignal sensor,
A biometric signal sensor unit 100 mounted on a blood vessel in the body to observe biometric information including a structure, function, and variation of the blood vessel, and measure and calculate biometric information including blood flow, blood flow rate, blood pressure, and body temperature;
A wireless communication unit 200 for wirelessly transmitting the biometric information observed, measured, and calculated by the biosignal sensor unit 100;
A database server 300 for collecting and storing the biometric information received from the wireless communication unit 200; And
The structure and function of blood vessels through an implantable bio-signal sensor, characterized in that it comprises a smart device 400 that processes the biometric information collected and stored in the database server 300 and displays it through a medical education application. And a system for medical education capable of observing mutations (10). The method of claim 1, wherein the biosignal sensor unit 100,
A medical education system (10) capable of observing a blood vessel structure, function, and mutation through an implantable biological signal sensor, characterized in that it is mounted on a blood vessel within the body of a person, a human body, or an animal. The method of claim 2, wherein the biosignal sensor unit 100,
A medical education system (10) capable of observing a blood vessel structure, function, and mutation through an implantable biological signal sensor, characterized in that it is mounted on an artery among blood vessels in the body. The method of claim 1, wherein the biosignal sensor unit 100,
A capacitive sensor 110 for observing the structure, function, and variation of the blood vessel to which the bio-signal sensor unit 100 is mounted, and measuring the amount of blood flow and the blood flow rate passed through;
A temperature sensor 120 measuring a body temperature at a location where the biosignal sensor unit 100 is mounted; And
The capacitive sensor 110 and the temperature sensor 120 collects data observed and measured in real time, and includes a calculation module 130 that calculates blood pressure using blood flow and blood flow velocity data among the collected data. A medical education system (10) capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor. The method of claim 4, wherein the capacitive sensor (110),
A measurement capacitive sensor 111 for observing the structure, function, and variation of blood vessels, and measuring the amount of blood flow passed and the blood flow rate; And
The measurement capacitive sensor 111 observes the structure, function, and variation of blood vessels, and includes a reference capacitive sensor 112 that serves as a reference for measuring the amount of blood flow and the blood flow rate passed through. A system for medical education (10) capable of observing a blood vessel structure, function, and mutation through an implantable biological signal sensor. The method of claim 5, wherein the capacitive sensor (110),
It is composed of a flexible material, characterized in that it is a ring-shaped sensor that surrounds the blood vessel in accordance with the cylindrical shape of the blood vessel on which the capacitive sensor 110 is mounted, , Function and mutation observation is possible medical education system (10). The method of claim 6, wherein the capacitive sensor (110),
An implantable biosignal sensor, characterized in that it is a sensor optimized for vascular wall mounting by using finite element analysis, designed to sense the blood vessel wall existing between the blood as a measurement target material and the capacitive sensor 110 Medical education system (10) through which the vascular structure, function and mutation can be observed. The method of claim 4, wherein the temperature sensor (120),
A system for medical education capable of observing blood vessel structure, function, and mutation through an implantable biosignal sensor, characterized in that it is a digital temperature sensor using a Monolithic CMOS IC in which processing, correction, and interface of the measured signal are integrated. . The method of claim 1, wherein the smart device 400,
Processing the biometric information in real time collected in the database server 300 and the biometric information previously stored in the database server 300 and converted into a database for learning through a compensation algorithm, and displaying each or simultaneously through an application for vascular medicine education A medical education system 10 capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor. The method of claim 1,
A blood vessel structure through an implantable biosignal sensor, characterized in that it further comprises a power supply unit 500 that provides power to the biosignal sensor unit 100 and the wireless communication unit 200 and is charged wirelessly, A system for medical education capable of observing functions and mutations (10). As a driving method of a medical education system 10 capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor,
(1) The biometric signal sensor unit 100 mounted on the blood vessel in the body observes biometric information including the structure, function, and mutation of the blood vessel, and measures biometric information including blood flow, blood flow rate, blood pressure, and body temperature. Calculating;
(2) wirelessly transmitting the biometric information observed, measured and calculated in step (1) from the wireless communication unit 200;
(3) collecting and storing the biometric information received in step (2) in the database server 300; And
(4) Process the biometric information collected and stored in step (3), and display it through an application for medical education. A method of driving the system 10 for medical education that can be observed. The method of claim 11, wherein in step (1),
A medical education system capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor, characterized in that the biosignal sensor unit 100 is mounted on a blood vessel in the body of a person, a human body, or an animal to measure biometric information (10) driving method. The method of claim 12, wherein in the step (1),
The method of driving a medical education system 10 capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor, wherein the biosignal sensor unit 100 is mounted on an artery among blood vessels in the body. The method of claim 11, wherein the step (1),
(1-1) The structure, function, and variation of the blood vessel in which the biosignal sensor unit 100 is mounted are observed by the capacitive sensor 110, and the amount of blood flow and the blood flow rate passed through the blood vessel are observed by the capacitive sensor 110. Measuring at;
(1-2) measuring the body temperature at the position where the bio-signal sensor unit 100 is mounted by the temperature sensor 120; And
(1-3) Collecting the data observed and measured in real time in steps (1-1) and (1-2), but calculating blood pressure using blood flow and blood flow rate data among the collected data. A method of driving a medical education system 10 capable of observing a blood vessel structure, function, and mutation through an implantable biosignal sensor, characterized in that it is implemented, including. The method of claim 14, wherein the capacitive sensor (110),
A measurement capacitive sensor 111 for observing the structure, function, and variation of blood vessels, and measuring the amount of blood flow passed and the blood flow rate; And
The measurement capacitive sensor 111 observes the structure, function, and variation of blood vessels, and includes a reference capacitive sensor 112 that serves as a reference for measuring the amount of blood flow and the blood flow rate passed through. The method of driving a medical education system 10 capable of observing a blood vessel structure, function, and mutation through an implantable biological signal sensor. The method of claim 15, wherein the capacitive sensor (110),
It is composed of a flexible material, characterized in that it is a ring-shaped sensor that surrounds the blood vessel in accordance with the cylindrical shape of the blood vessel on which the capacitive sensor 110 is mounted, , A method of driving a medical education system 10 capable of observing functions and mutations. The method of claim 16, wherein the capacitive sensor (110),
An implantable biosignal sensor, characterized in that it is a sensor optimized for vascular wall mounting by using finite element analysis, designed to sense the blood vessel wall existing between the blood as a measurement target material and the capacitive sensor 110 The driving method of the medical education system 10 through which the vascular structure, function, and mutation can be observed. The method of claim 14, wherein the temperature sensor (120),
A system for medical education capable of observing blood vessel structure, function, and mutation through an implantable biosignal sensor, characterized in that it is a digital temperature sensor using a Monolithic CMOS IC in which processing, correction, and interface of the measured signal are integrated. Method of driving. The method of claim 11, wherein in step (4),
It characterized in that the biometric information in real time collected in step (3) and the biometric information previously stored in step (3) and converted into a database for learning are processed through a compensation algorithm, and displayed individually or simultaneously through an application for vascular medicine education. A method of driving a medical education system 10 capable of observing a blood vessel structure, function, and mutation through an implantable biological signal sensor. The method of claim 11,
(5) observing the structure, function and mutation of blood vessels through an implantable biosignal sensor, characterized in that the step (1) and step (2) are further implemented by providing power and charging wirelessly A method of driving the medical education system 10 possible.

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