KR20210012551A - Implantable device for monitoring biometric data in real time and its way to working - Google Patents

Abstract

The present invention relates to a biometric information real-time monitoring system for blood vessel implantation in a body and a driving method thereof. The biometric information real-time monitoring system for blood vessel implantation in a body comprises: a biometric signal sensor unit mounted on a blood vessel in a body of a user; a wireless communication unit wirelessly transmitting biometric information; and a monitoring unit outputting the biometric information of the user so that the user monitors the biometric information in real time. Therefore, by using finite element analysis, the system can be optimized for blood vessel wall mounting.

Description

Intra-body blood vessel transplantation type biometric information real-time monitoring system and its driving method {IMPLANTABLE DEVICE FOR MONITORING BIOMETRIC DATA IN REAL TIME AND ITS WAY TO WORKING}

The present invention relates to a system for real-time monitoring of biometric information, and more particularly, to a system for monitoring real-time biometric information of an in vivo blood vessel implantation type.

Cardiovascular diseases such as angina pectoris and myocardial infarction are the major causes of adult mortality in Korea as well as in developed countries, and the prevalence rate is increasing rapidly. In particular, arteriosclerosis causes problems with blood circulation by reducing the function of various organs and narrowing or blocking the coronary arteries that supply blood to the heart, resulting in angina pectoris or myocardial infarction, and cerebral infarction and cerebral hemorrhage, which block blood vessels to the brain. 1 is a view showing the trend of increasing medical expenses and salary expenses related to cardiovascular diseases in Korea. As shown in Fig. 1, according to health insurance statistics in 2014, the medical insurance benefit cost related to cardiovascular disease in Korea was about 5,320 billion won, which is more than five times higher than about 1.1 trillion won in 2004, and an annual average increase of 17.3%. In that it can be seen, the rate of rapid increase in prevalence can be seen.

Although many methods of measuring blood pressure in vitro have been developed to observe and prevent cardiovascular diseases such as arteriosclerosis, but this has disadvantages that it is difficult to accurately measure blood pressure and cannot observe and record data in real time. Accordingly, there are many studies on bio-signals through an implantable system in recent years. As an example, there is a device capable of measuring blood pressure, blood flow rate, and body temperature in an artery by inserting a catheter. 2 is a view showing a catheter, which is a conventional device for measuring bio-signals inserted into the body. As shown in FIG. 2, this method can obtain accurate biometric data, but since the device must be continuously inserted into the body, the risk of infection is high, and the patient must be lying down. In addition, since the structure of the human body appears in various ways, the system may malfunction or cause problems accordingly. Therefore, there is a need for a system capable of accurately and conveniently measuring blood pressure and body temperature through implantation in the body.

Meanwhile, as a prior art related to the present invention, Korean Patent Registration No. 10-1647507 (name of the invention: a system and method for acquiring cardiovascular disease diagnosis data using a capacitive-based vascular implantable biosensor, notification date: August 10, 2016 Work) and the like have been disclosed.

The present invention has been proposed to solve the above problems of the previously proposed methods, and by using an implantable biosignal sensor composed of a capacitive sensor and a temperature sensor, the device is not exposed to the external environment. It can reduce the risk, and even with a single implant, it is possible to accurately and continuously observe the blood pressure and internal body temperature of the user's blood vessel for a long time, and because the biosignal sensor can be attached to various locations in the body, It is an object of the present invention to provide a system for real-time monitoring of intra-body blood vessel transplantation type biometric information and a driving method thereof that can observe changes in blood vessels.

In addition, the present invention, by using a capacitive sensor in the form of a ring formed to fit a variety of cylindrical blood vessels, it is possible to measure the amount of blood flow and the blood flow rate without error even when the blood vessel is changed, and the blood and the capacitive material to be measured are Another object of the present invention is to provide a system for real-time monitoring of intra-body blood vessel implantation-type biometric information and a driving method that is optimized for vascular wall mounting by using finite element analysis by designing a capacitive sensor to sense the vessel wall existing between the sensors. To do.

In addition, the present invention transmits the information measured through the biometric sensor to the monitoring device, so that the user can accurately monitor the received biometric information of the user in real time, and the presence of contaminants in the blood vessel or the state of blood flow. It is possible to observe immediately, according to the user's health status, more quickly coping with it, and by using a wireless communication and wireless charging device on the sensor, it is possible to carry out daily life without discomfort even when the sensor is installed in the body. Another object is to provide a system for monitoring biometric information and a method for driving the same.

In order to achieve the above object, the system for real-time monitoring of intra-body blood vessel transplantation type biometric information according to a feature of the present invention,

As a real-time monitoring system for blood vessel transplantation type biometric information

A biometric signal sensor unit mounted on a user's blood vessel to measure and calculate biometric information including a user's blood pressure, blood flow, and body temperature;

A wireless communication unit for wirelessly transmitting the user's biometric information measured and calculated by the biometric signal sensor unit; And

It is characterized by its configuration to include a monitoring unit for outputting the user's biometric information received from the wireless communication unit to allow the user to monitor in real time.

Preferably, the biometric signal sensor unit,

It may be mounted on an artery among blood vessels in the user's body.

Preferably, the biometric signal sensor unit,

A capacitive sensor measuring the structure and function of a blood vessel in which the bio-signal sensor unit is mounted, and a blood flow rate and a blood flow rate;

A temperature sensor measuring body temperature at a location where the biometric signal sensor unit is mounted; And

The capacitive sensor and the temperature sensor collect data measured in real time, and may include a calculation module that calculates the user's blood pressure by using the user's blood flow and blood flow velocity data among the collected data.

More preferably, the capacitive sensor,

A measuring capacitive sensor that measures the structure and function of the user's blood vessel, the amount of blood flow passed, and the blood flow rate; And

The measurement capacitive sensor may include a reference capacitive sensor, which is a reference for measuring the structure and function of the user's blood vessel, the amount of blood flow passed, and the blood flow rate.

Even more preferably, the capacitive sensor,

It is made of a flexible material, and may be a ring-shaped sensor surrounding the blood vessel in accordance with the cylindrical shape of the blood vessel on which the capacitive sensor is mounted.

Even more preferably, the capacitive sensor,

It is designed to sense the blood vessel wall existing between the user's blood as a measurement target material and the capacitive sensor, and may be a sensor optimized for mounting a vessel wall using finite element analysis.

Even more preferably, the capacitive sensor,

The foreign matter in the user's blood may be measured by detecting a change in dielectric constant according to the foreign matter present in the user's blood.

More preferably, the temperature sensor,

It may be a digital temperature sensor using a Monolithic CMOS IC in which the processing, correction, and interface of the measured signal are integrated.

Preferably, the monitoring unit,

The user's real-time biometric information received from the wireless communication unit may be accumulated and stored, and the change trend may be displayed together.

Preferably,

It may be configured to further include a power supply that provides power to the bio-signal sensor unit and the wireless communication unit and is charged wirelessly.

In order to achieve the above object, a method of driving a system for real-time monitoring of intra-body blood vessel implantation type biometric information according to a feature of the present invention includes:

As a driving method of a real-time monitoring system for intra-body blood vessel transplantation type biometric information,

(1) measuring and calculating biometric information including a user's blood pressure, blood flow, and body temperature by mounting a biometric signal sensor unit on a blood vessel in the user's body;

(2) wirelessly transmitting the user's biometric information measured and calculated in step (1); And

(3) The implementation feature includes the step of outputting the user's biometric information received in step (2) so that the user can monitor it in real time.

Preferably, in step (1),

The biosignal sensor unit may be mounted on an artery among blood vessels in the user's body.

Preferably, the step (1),

(1-1) measuring the structure and function of the blood vessel in which the bio-signal sensor unit is mounted, the amount of blood flow passed, and the blood flow rate by a capacitive sensor;

(1-2) measuring a body temperature at a location where the bio-signal sensor unit is mounted using a temperature sensor; And

(1-3) Collects the data measured in real time in steps (1-1) and (1-2), but calculates the user's blood pressure using the user's blood flow and blood flow rate data among the collected data. It may be implemented including the step of.

More preferably, the capacitive sensor,

A measuring capacitive sensor that measures the structure and function of the user's blood vessel, the amount of blood flow passed, and the blood flow rate; And

The measurement capacitive sensor may include a reference capacitive sensor, which is a reference for measuring the structure and function of the user's blood vessel, the amount of blood flow passed, and the blood flow rate.

Even more preferably, the capacitive sensor,

It is made of a flexible material, and may be a ring-shaped sensor surrounding the blood vessel in accordance with the cylindrical shape of the blood vessel on which the capacitive sensor is mounted.

Even more preferably, the capacitive sensor,

It is designed to sense the blood vessel wall existing between the user's blood as a measurement target material and the capacitive sensor, and may be a sensor optimized for mounting a vessel wall using finite element analysis.

Even more preferably, the capacitive sensor,

The foreign substance in the user's blood may be measured by detecting a change in dielectric constant according to the foreign substance present in the user's blood.

More preferably, the temperature sensor,

It may be a digital temperature sensor using a Monolithic CMOS IC in which the processing, correction, and interface of the measured signal are integrated.

Preferably, in step (3),

The real-time biometric information of the user received in step (2) may be accumulated and stored, and the change trend may be displayed together.

Preferably,

It may be configured to further include a power supply that provides power to the steps (1) and (2) and is charged wirelessly.

According to the system for real-time monitoring of intra-body blood vessel implantation type biometric information and its driving method proposed in the present invention, by using an implantable biosignal sensor composed of a capacitive sensor and a temperature sensor, the device is not exposed to the external environment, so infection. It is possible to reduce the risk of blood pressure and internal body temperature of the user's arteries for a long time with a single implantation, and to accurately and continuously observe the blood pressure and internal body temperature of the user, and because the biometric signal sensor can be attached to various locations in the body, Changes in the arteries can also be observed.

In addition, according to the system for real-time monitoring of intra-body blood vessel grafting type biometric information and its driving method proposed in the present invention, by using a capacitive sensor in a ring shape formed to fit various cylindrical blood vessels, it is possible to change arterial blood vessels without error. By designing a capacitive sensor to measure blood flow and blood flow velocity, taking into account the vessel wall existing between the blood and the capacitive sensor, which is the substance to be measured, it can be optimized for vessel wall mounting using finite element analysis. have.

In addition, according to the system for real-time monitoring of intra-body blood vessel implantation type biometric information and its driving method proposed in the present invention, the received biometric information of the user is transmitted to the monitoring device by transmitting the information measured through the biosignal recognition sensor. It is possible to accurately monitor in real time and immediately observe the presence of contaminants in blood vessels or the state of blood flow, enabling a more rapid response according to the user's health status, and wireless communication and wireless charging devices are used for the sensor. By doing so, you can live your daily life without any inconvenience even with the sensor installed in your body.

1 is a view showing the trend of increasing domestic cardiovascular disease-related medical expenses and salary expenses.
2 is a view showing a catheter, which is a conventional device for measuring bio-signals inserted into the body.
3 is a diagram showing a configuration of a system for real-time monitoring of intra-body blood vessel implantation type biometric information as a functional block according to an embodiment of the present invention.
4 is a diagram showing a basic conceptual diagram of a system for real-time monitoring of intra-body blood vessel implantation type biometric information according to an embodiment of the present invention.
FIG. 5 is a diagram showing a configuration of a biosignal sensor of a system for real-time monitoring of intra-body blood vessel implantation type biometric information as a function block according to an embodiment of the present invention.
6 is a diagram showing a configuration of a capacitive sensor of a system for real-time monitoring of intra-body blood vessel implantation type biometric information as a functional block according to an embodiment of the present invention.
7 is a schematic diagram of a circuit diagram of a capacitive sensor, a system for real-time monitoring of biometric information of a blood vessel implantation type in a body according to an embodiment of the present invention.
8 is a schematic perspective view of a system for real-time monitoring of intra-body blood vessel implantation type biometric information according to an embodiment of the present invention.
9 is a diagram showing a principle of separating and calculating a capacitive component of an arterial wall permittivity and a blood permittivity in a capacitive sensor of a system for real-time monitoring of biometric information in a blood vessel implantation type according to an embodiment of the present invention.
FIG. 10 is a diagram illustrating a simulation method for optimizing a capacitive sensor of a system for real-time monitoring of intra-body blood vessel implantation type biometric information according to an embodiment of the present invention using finite element analysis.
11 is a diagram showing a conceptual diagram of an in vitro experiment for confirming the performance of a capacitive sensor, a system for real-time monitoring of biometric information of a blood vessel implantation type in a body according to an embodiment of the present invention.
12 is a diagram illustrating a flow of a driving method of a system for monitoring a system for real-time blood vessel transplantation type biometric information according to an embodiment of the present invention.
13 is a diagram illustrating a flow of a method of driving a biosignal sensor unit in a system for real-time monitoring of biometric information of a blood vessel implantation type according to an embodiment of the present invention.

Hereinafter, preferred embodiments will be described in detail with reference to the accompanying drawings so that those of ordinary skill in the art may easily implement the present invention. However, in describing a preferred embodiment of the present invention in detail, if it is determined that a detailed description of a related known function or configuration may unnecessarily obscure the subject matter of the present invention, the detailed description thereof will be omitted. In addition, the same reference numerals are used throughout the drawings for portions having similar functions and functions.

In addition, throughout the specification, when a part is said to be connected to another part, this includes not only the case that it is directly connected, but also the case that it is indirectly connected with another element interposed therebetween. In addition, the inclusion of certain components means that other components may be further included rather than excluding other components unless specifically stated to the contrary.

FIG. 3 is a diagram showing the configuration of a system for monitoring real-time blood vessel transplantation type biometric information 10 according to an embodiment of the present invention as a functional block, and FIG. 4 is a diagram illustrating a blood vessel transplantation-type living body in the body according to an embodiment of the present invention. It is a diagram showing a basic conceptual diagram of the information real-time monitoring system 10. As shown in FIGS. 3 to 4, the system 10 for real-time monitoring of intra-body blood vessel implantation type biometric information according to an embodiment of the present invention includes the user's blood pressure, blood flow, and body temperature. The biometric signal sensor unit 100 for measuring and calculating biometric information, the wireless communication unit 200 for wirelessly transmitting the user's biometric information measured and calculated by the biosignal sensor unit 100, and the reception from the wireless communication unit 200 It may be configured to include a monitoring unit 300 that outputs the user's biometric information to be monitored in real time, and provides power to the biosignal sensor unit 100 and the wireless communication unit 200, and is wirelessly charged. It may be configured to further include a power supply unit 400.

The biosignal sensor unit 100 is a sensing device that is mounted on a blood vessel in the user's body and measures a user's biosignal including blood pressure, blood flow, and body temperature. In other words, blood pressure refers to the pressure exerted on the walls of blood vessels when blood flows through the blood vessel. According to the name of the blood vessel, it can be classified as arterial blood pressure, capillary blood pressure, and venous blood pressure, and usually blood pressure means arterial blood pressure. At this time, arterial blood pressure fluctuates by the heartbeat. In the case of the present invention, it is mounted on an artery among blood vessels in the user's body to measure vital signs such as blood pressure in the artery.

FIG. 5 is a diagram showing the configuration of a biosignal sensor unit 100 of a system for real-time monitoring of intra-body blood vessel implantation type biometric information as a functional block according to an embodiment of the present invention. The biosignal sensor unit 100 of the system for real-time monitoring of biometric information of a blood vessel implantation type in the body according to an embodiment of the present invention includes a structure and function of a blood vessel in which the biosignal sensor unit 100 is mounted, and the amount of blood flow passed through and the blood flow rate. Measured in real time by the capacitive sensor 110 to measure, the temperature sensor 120 to measure the body temperature at the location where the biosignal sensor unit 100 is mounted, and the capacitive sensor 110 and the temperature sensor 120 The collected data may be configured to include a calculation module 130 that calculates the user's blood pressure by using the user's blood flow rate and blood flow rate data among the collected data.

6 is a diagram showing a configuration of a capacitive sensor 110 of a system for real-time monitoring of intra-body blood vessel implantation type biometric information as a function block according to an embodiment of the present invention. The capacitive sensor 110 of the system for real-time monitoring of intra-body blood vessel implantation type biometric information according to an embodiment of the present invention includes a measurement capacitive sensor for measuring the structure and function of the user's blood vessel, the amount of blood flow passed, and the blood flow rate ( 111), and a reference capacitive sensor 112, which is a reference for measuring the structure and function of the user's blood vessel, the amount of blood flow passed, and the blood flow rate by the measurement capacitive sensor 111. Hereinafter, the principle, configuration and arrangement of the capacitive sensor 110 will be described in detail.

When there is a dielectric between the two electrode plates, a capacitor is formed regardless of the shape or size of the conductor. When a DC voltage source is connected to the two electrode plates, the surface of the two electrode plates connected to the positive and negative power terminals Positive and negative charges accumulate. Capacitance of a capacitor made of two poles is defined as the value obtained by dividing the total amount of charge of an object by the voltage of the object. Dielectric constant is the physical effect that the medium between the charges has on the electric field when an electric field acts between them. It is a unit, and it can also be viewed as the amount of charge a medium can store. At this time, even with the same amount of material, if the dielectric constant is higher, more charges can be stored, so that the capacitance increases. The capacitive sensor 110 measures the amount of liquid using static electricity in a container in which the liquid flows. More specifically, when the amount of blood flow changes, the ratio of the portion occupied by air and the portion occupied by blood flow in the capacitor area Blood flow can be measured through the change in permittivity caused by That is, the amount of blood flow may be calculated through Equation 1 below according to the capacitance value measured through the electrode of the capacitive sensor 110.

In addition, by designing the capacitive sensor 110 as a blood flow measurement sensor and a blood flow velocity measurement sensor, both blood flow and blood flow velocity can be measured through the capacitive sensor 110, and the blood vessel The vascular structure, such as the diameter and the thickness of the vascular wall, can also be measured.

7 is a diagram showing a circuit conceptual diagram of a capacitive sensor 110 for a system for real-time monitoring of intra-body blood vessel implantation type biometric information according to an embodiment of the present invention. As shown in FIG. 7, the capacitive sensor 110, a system for real-time monitoring of biometric information of blood vessel implantation in a body according to an embodiment of the present invention, is connected to an MCU through a MUX, and the collected data is signaled through an analog comparator. Treatment can be carried out. The measurement capacitive sensor 111 and the reference capacitive sensor 112 constituting the capacitive sensor 110 are attached to and installed on the vessel wall, and may be spaced apart from each other to prevent electric field interference.

FIG. 8 is a schematic perspective view of a system 10 for real-time monitoring of intra-body blood vessel implantation type biometric information according to an embodiment of the present invention. As shown in FIG. 8, the capacitive sensor 110 of the system for real-time monitoring of intra-body blood vessel implantation type biometric information according to an embodiment of the present invention is made of a flexible material, and the capacitive sensor 110 ) May be a sensor in the form of a ring surrounding the blood vessel in accordance with the cylindrical shape of the blood vessel to be mounted. That is, since the artery is in a cylindrical shape, the capacitive sensor should also be designed in an annular shape. Since most capacitive sensors are made of a flat plate, in the present invention, the capacitive of the flat plate can be approached in an annular shape. Equation 2 below can be derived so that it is possible to complete the mathematical model of the circular capacitive sensor 110 by using this.

FIG. 9 is a diagram showing a principle of separating and calculating the capacitive component of the arterial wall permittivity and the blood permittivity in the capacitive sensor 110 of the system for real-time monitoring of biometric information based on blood vessel implantation in the body according to an embodiment of the present invention. , FIG. 10 is a diagram showing a simulation method of optimizing the capacitive sensor 110 of the system for real-time monitoring of intra-body blood vessel implantation type biometric information according to an embodiment of the present invention using finite element analysis. 9 to 10, the capacitive sensor 110 of the system for real-time monitoring of intra-body blood vessel implantation type biometric information according to an embodiment of the present invention includes a user's blood and a capacitive sensor as a measurement target material. It is designed to sense the vessel wall existing between (110), and may be a sensor optimized for vessel wall mounting using finite element analysis.

More specifically, a general capacitive sensor directly contacts the measurement material, but in the present invention, since the capacitive sensor 110 is located above the arterial blood vessel, there is an arterial wall between the blood flow and the capacitive sensor 110. , As shown in FIG. 9, two capacitive components, the dielectric constant 2 of the inner wall of the artery and the dielectric constant 1 of the blood, can be separated and identified. That is, assuming that there is an artery between 1 of the blood to be measured and the capacitive sensor 110, it can be applied to the present invention through Equation 3 below. Here, in the case of Equation 3, in order to avoid the end effect, the electrode thickness of the capacitive sensor 110 is 0, has an infinite conductivity, and can be obtained by assuming that the length of the electrode is greater than the width. You can find the C value between the two electrolytes.

As shown in FIG. 10, using the derived Equation 3 and the 2D computational model of FIG. 9, the appearance of the capacitive sensor 110 attached outside the blood vessel in COMSOL software can be designed through finite element modeling. In addition, through this, the capacitive sensor 110 can be optimized.

In addition, the capacitive sensor 110 may measure foreign substances present in the user's blood. More specifically, the capacitive sensor 110 may measure a foreign substance in the user's blood by detecting a change in dielectric constant according to a foreign substance present in the user's blood.

FIG. 11 is a diagram showing a conceptual diagram of an in vitro experiment for confirming the performance of the capacitive sensor 110, a system for real-time monitoring of biometric information of a blood vessel implantation type in a body according to an embodiment of the present invention. As shown in FIG. 11, the capacitive sensor 110 of the system for real-time monitoring of intra-body blood vessel implantation type biometric information according to an embodiment of the present invention may test blood pressure measurement performance through an in-vitro in vitro experiment. . More specifically, performance can be checked using the aorta of the body. After connecting one liquid container to each end of the blood vessel, a process in which blood flow from the blood vessel is littered in one direction is simulated using a peristaltic pump. At this time, after the sensor is fixed outside the blood vessel and connected to an ICR (Inductance, Capacitive, Resistance) meter that can measure the capacitance value, the change in the capacitance value can be observed while controlling the pump's export pressure.

The temperature sensor 120 may be a digital temperature sensor using a monolithic CMOS IC in which processing, correction, and interface of a measured signal are integrated. More specifically, the temperature sensor 120 may use a Monolithic CMOS IC in which processing, correction, and interface of the measured signal are integrated, and the microcontroller for driving the system is a 32-bit energy-efficient ARM Cortex M3 architecture. By using the microcontroller EFM32, it is possible to ensure operation at a low current and ensure a longer period of use in the body.

The calculation module 130 may collect data measured in real time by the capacitive sensor 110 and the temperature sensor 120, and use the user's blood flow and blood flow velocity data among the collected data to determine the user's blood pressure. Can be calculated. That is, the calculation module 130 may be a microcontroller unit (MCU) that performs a function by making a microprocessor and an input/output module into one chip, and is received from the capacitive sensor 110 and the temperature sensor 120. Data is passed to the MCU. The MCU can analyze and process data through an algorithm designed inside, and in particular, it can calculate the user's blood pressure using blood flow and blood flow velocity data.

The wireless communication unit 200 may wirelessly transmit the user's biometric information measured and calculated by the biometric signal sensor unit 100 to the monitoring unit 300. That is, a circuit can be manufactured so that all data measured by the in vivo biosignal sensor unit 100 is transmitted to the external monitoring unit 300 using a wireless communication method such as Bluetooth.

The monitoring unit 300 may output the user's biometric information received from the wireless communication unit 200 to the user to monitor in real time. More specifically, the real-time monitoring management program may be implemented based on LabVIEW, and through the monitoring program, the monitoring unit 300 accumulates and stores real-time biometric information of the user received from the wireless communication unit 200 and tracks the change trend. I can show you together.

In an embodiment of the present invention, the system 10 for real-time monitoring of biometric information based on blood vessel implantation in the body provides power to the biosignal sensor unit 100 and the wireless communication unit 200, and provides a power supply unit 400 that is wirelessly charged. It can be included more. That is, by allowing the power supply unit 400 to be charged wirelessly, patients can live daily life for a long time even after implanting the present invention in the body, and use and management of the device to be inserted into the body can be made more convenient.

The system 10 for real-time monitoring of intra-body blood vessel grafting type biometric information according to an embodiment of the present invention may check its performance through animal experiments. More specifically, after attaching the sensor to the artery of the rat and fixing the implantable device to the stomach of the rat, the measured data is wirelessly collected by saving the animal again. By transmitting the collected data to a monitoring program, displaying and storing it, it is possible to check the performance of the system 10 for real-time monitoring of intra-body blood vessel implantation type biometric information according to an embodiment of the present invention.

FIG. 12 is a diagram illustrating a flow of a driving method of a system for real-time blood vessel transplantation type biometric information according to an embodiment of the present invention, and FIG. 13 is a real-time monitoring system for blood vessel transplantation type biometric information in a body according to an embodiment of the present invention. It is a diagram showing a flow of a method of driving a biosignal sensor unit. As shown in FIGS. 12 to 13, in the driving method of the system 10 for real-time blood vessel transplantation type biometric information according to an embodiment of the present invention, the biosignal sensor unit 100 is mounted on the user's blood vessel. Measuring and calculating biometric information including the user's blood pressure, blood flow, and body temperature (S100), wirelessly transmitting the user's biometric information measured and calculated in step S100 (S200), and received in step S200 It may be implemented including a step (S300) of outputting the user's biometric information so that the user monitors it in real time, and the step S100 includes the structure and function of the blood vessel on which the biosignal sensor unit 100 is mounted, the amount of blood flow passed through, and the blood flow. The step of measuring the speed with the capacitive sensor 110 (S110), the step of measuring the body temperature at the position where the biosignal sensor unit 100 is mounted (S120), and the steps S110 and S120 Collecting the data measured in real time in the, but may be implemented including the step (S130) of calculating the user's blood pressure using the user's blood flow and blood flow rate data among the collected data.

Details related to each step have been sufficiently described in relation to the system for real-time monitoring of intra-body blood vessel transplantation type biometric information according to an embodiment of the present invention, and thus detailed descriptions will be omitted.

As described above, according to the system for real-time blood vessel transplantation type biometric information monitoring system and its driving method according to an embodiment of the present invention, by using an implantable biosignal sensor composed of a capacitive sensor and a temperature sensor, the device is Because it is not exposed to the environment, it is possible to reduce the risk of infection.It is possible to accurately and continuously observe the blood pressure and internal body temperature of the user's arteries for a long time with a single implantation, and the biometric signal sensor can be attached to various locations in the body. Therefore, it is possible to observe changes in arteries according to the attached location. In addition, by using a capacitive sensor in a ring shape formed to fit various cylindrical blood vessels, it is possible to measure the blood flow and blood flow rate without error even in the variation of arterial blood vessels, and exist between the blood and the capacitive sensor, which is a measurement target material. By designing the capacitive sensor to sense the vessel wall in consideration of the vessel wall, it is possible to optimize the vessel wall mounting using finite element analysis. In addition, by transmitting the information measured through the biometric sensor to the monitoring device, the user can accurately monitor the received user's biometric information in real time, and immediately observe the presence of contaminants in blood vessels or the state of blood flow. As a result, it is possible to respond more quickly according to the user's health condition, and by using a wireless communication and wireless charging device for the sensor, even when the sensor is installed in the body, daily life can be performed without inconvenience.

The present invention described above can be modified or applied in various ways by those of ordinary skill in the technical field to which the present invention belongs, and the scope of the technical idea according to the present invention should be determined by the following claims.

10: Blood vessel transplant type biometric information real-time monitoring system
100: biosignal sensor unit
110: capacitive sensor
111: measuring capacitive sensor
112: reference capacitive sensor
120: temperature sensor
130: arithmetic module
200: Ministry of Wireless Communication
300: monitoring unit
400: power unit
S100: Step of measuring and calculating biometric information of blood pressure, blood flow, and body temperature by mounting a biometric signal sensor unit on blood vessels in the body
S110: Step of measuring the structure and function of the blood vessel equipped with the biosignal sensor unit, the amount of blood flow passed, and the blood flow rate by the capacitive sensor
S120: Step of measuring the body temperature at the location where the biometric signal sensor unit is mounted using the temperature sensor
S130: Collecting data measured in real time in steps S110 and S120, but calculating blood pressure using blood flow and blood flow rate data among the collected data.
S200: wirelessly transmitting the biometric information measured and calculated in step S100
S300: Outputting the biometric information received in step S200 to be monitored by the user in real time

Claims (20)

As an in vivo blood vessel transplant type biometric information real-time monitoring system 10,
A biometric signal sensor unit 100 mounted on a blood vessel of a user to measure and calculate biometric information including a user's blood pressure, blood flow, and body temperature;
A wireless communication unit 200 for wirelessly transmitting the user's biometric information measured and calculated by the biometric signal sensor unit 100; And
A system (10) comprising a monitoring unit (300) for outputting the user's biometric information received from the wireless communication unit (200) to allow the user to monitor in real time. . The method of claim 1, wherein the biosignal sensor unit 100,
A system (10) for real-time monitoring of intra-body blood vessel implantation type biometric information, characterized in that it is mounted on an artery among blood vessels in the user's body. The method of claim 1, wherein the biosignal sensor unit 100,
A capacitive sensor 110 measuring the structure and function of a blood vessel in which the bio-signal sensor unit 100 is mounted, the amount of blood flow passed through, and a blood flow rate;
A temperature sensor 120 measuring a body temperature at a location where the biosignal sensor unit 100 is mounted; And
An operation module 130 that collects data measured in real time by the capacitive sensor 110 and the temperature sensor 120, and calculates the user's blood pressure by using the user's blood flow and blood flow velocity data among the collected data. ), characterized in that it is configured to include, in vivo blood vessel transplantation type biometric information real-time monitoring system (10). The method of claim 3, wherein the capacitive sensor (110),
A measurement capacitive sensor 111 for measuring the structure and function of the user's blood vessel, the amount of blood flow passed, and the blood flow rate; And
In the body, characterized in that it comprises a reference capacitive sensor 112, which is a reference for measuring the structure and function of the user's blood vessel, the amount of blood flow passed, and the blood flow rate by the measurement capacitive sensor 111 Blood vessel transplant type biometric information real-time monitoring system (10). The method of claim 4, wherein the capacitive sensor (110),
A real-time monitoring system for intra-body blood vessel implantation type biometric information, which is made of a flexible material and is a ring-shaped sensor that surrounds the blood vessel in accordance with the cylindrical shape of the blood vessel on which the capacitive sensor 110 is mounted. (10). The method of claim 5, wherein the capacitive sensor (110),
Designed to sense the blood vessel wall existing between the user's blood, which is a measurement target, and the capacitive sensor 110, and is a sensor optimized for vascular wall mounting using finite element analysis. Type biometric information real-time monitoring system (10). The method of claim 6, wherein the capacitive sensor (110),
In vivo blood vessel transplantation type biometric information real-time monitoring system (10), characterized in that it is possible to measure the foreign substance in the user's blood by detecting a change in dielectric constant according to the foreign substance present in the user's blood. The method of claim 3, wherein the temperature sensor (120),
A digital temperature sensor using a Monolithic CMOS IC in which processing, correction, and interface of the measured signal are integrated, is used. The method of claim 1, wherein the monitoring unit 300,
The real-time biometric information of the user received from the wireless communication unit 200 is accumulated and stored, and the change trend is displayed together. The method of claim 1,
The bio-signal sensor unit 100 and the wireless communication unit 200 are provided with power, and a power supply unit 400 that is wirelessly charged is further included. 10). As a driving method of the in vivo blood vessel transplant type biometric information real-time monitoring system 10,
(1) measuring and calculating biometric information including the user's blood pressure, blood flow, and body temperature by mounting the biometric signal sensor unit 100 on a blood vessel in the user's body;
(2) wirelessly transmitting the user's biometric information measured and calculated in step (1); And
(3) Driving of the system 10 for real-time monitoring of intra-body blood vessel implantable biometric information, characterized in that it is implemented including the step of outputting the user's biometric information received in step (2) so that the user monitors in real time Way. The method of claim 11, wherein in step (1),
The method of driving the system (10) for real-time monitoring of biometric information of a blood vessel implantation type in a body, characterized in that the biosignal sensor unit (100) is mounted on an artery among blood vessels in the user's body. The method of claim 11, wherein the step (1),
(1-1) measuring by the capacitive sensor 110 the structure and function of the blood vessel in which the bio-signal sensor unit 100 is mounted, the amount of blood flow passed and the blood flow rate;
(1-2) measuring the body temperature at the position where the bio-signal sensor unit 100 is mounted by the temperature sensor 120; And
(1-3) Collects the data measured in real time in steps (1-1) and (1-2), but calculates the user's blood pressure using the user's blood flow and blood flow rate data among the collected data. A method of driving the system 10 for real-time monitoring of intra-body blood vessel implantation type biometric information, characterized in that it is implemented including the step of. The method of claim 13, wherein the capacitive sensor (110),
A measurement capacitive sensor 111 for measuring the structure and function of the user's blood vessel, the amount of blood flow passed, and the blood flow rate; And
In the body blood vessel, characterized in that it comprises a reference capacitive sensor 112, which is a reference for measuring the structure and function of the user's blood vessel, the amount of blood passed and the blood flow rate by the measurement capacitive sensor 111 A method of driving the implantable biometric information real-time monitoring system 10. The method of claim 14, wherein the capacitive sensor (110),
A real-time monitoring system for intra-body blood vessel implantation type biometric information, which is made of a flexible material and is a ring-shaped sensor that surrounds the blood vessel in accordance with the cylindrical shape of the blood vessel on which the capacitive sensor 110 is mounted. (10) driving method. The method of claim 15, wherein the capacitive sensor (110),
Designed to sense the blood vessel wall existing between the user's blood, which is a measurement target, and the capacitive sensor 110, and is a sensor optimized for vascular wall mounting using finite element analysis. A method of driving the type biometric information real-time monitoring system 10. The method of claim 16, wherein the capacitive sensor (110),
The driving method of the system (10) for real-time blood vessel transplantation type biometric information monitoring system (10), characterized in that it is possible to measure the foreign substance in the user's blood by detecting a change in dielectric constant according to the foreign substance present in the user's blood. The method of claim 13, wherein the temperature sensor (120),
A method of driving the system 10 for real-time monitoring of biometric information of a blood vessel implantation type in a body, characterized in that it is a digital temperature sensor using a Monolithic CMOS IC in which processing, correction, and interface of the measured signal are integrated. The method of claim 11, wherein in the step (3),
The driving method of the system (10) for real-time monitoring of intra-body blood vessel implantation type biometric information (10), characterized in that the real-time biometric information of the user received in step (2) is accumulated and stored, and the change trend is displayed together. The method of claim 11,
Driving of the system 10 for real-time blood vessel implantation type biometric information monitoring system 10, characterized in that it further comprises a power supply unit 400 that provides power to the steps (1) and (2) and is charged wirelessly Way.

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