KR102470806B1 - Electroceutical monitoring system and server - Google Patents

Abstract

The present invention provides a system for monitoring electroceuticals, which comprises: electroceuticals buried under the skin to apply pre-set electrical stimulation to nerves; a main power module providing power to the electroceuticals and composed of a secondary battery capable of being repeatedly charged; an energy harvester module configured to perform self-powered generation in real time by using a friction element module and electrically connected to the main power module to charge the main power module subsidiarily; and a control module checking states of the electroceuticals, the main power module, and the energy harvester module, controlling the operations thereof, and having a communication unit capable of wirelessly communicating with a user terminal. Accordingly, the size of the system of the present invention can be miniaturized and the stability thereof can be maintained.

Description

Electronic monitoring system and server {Electroceutical monitoring system and server}

The present invention relates to an electronic medicine monitoring system and server.

Electronic medicine is a compound word of electronics and pharmaceutical, and means an electronic device that treats diseases by controlling electrical signals generated in the brain and nerve cells.

Today, electronic drugs are mainly used to improve disorders or problems occurring in nerves. The principle of electronic medicine is the concept of improving or normalizing the pathophysiological environment by stimulating various cells-tissues-organs including nerves with electrical signals generated through devices designed to be generated artificially or in response to body signals.

In the body, free ions, dipoles, and polarized molecules enable cells, tissues, and organs to generate and conduct electricity. Microscopic bioelectricity controls physiological phenomena and plays an important role in maintaining life. Homeostasis maintenance and harmony in living organisms are regulated by electrical and chemical signals, and electrical and chemical signals interact with each other. Changes in electrical signals can change chemical signals, and chemical signals can change electrical signals.

In the early days when electronic drugs were developed, simple implantable medical devices such as pacemakers were the main focus. Recently, electronic devices that stimulate nerve tissue are evolving to treat chronic diseases such as epilepsy, diabetes, arthritis, and high blood pressure.

Traditional drugs used in the past may cause side effects at unwanted sites while circulating through blood vessels. On the other hand, electronic drugs are safe for the human body because they select and stimulate only the specific nerves that need treatment. Since the electronic drug is buried under the skin and used, it selects and stimulates only a specific part that needs treatment, thereby minimizing side effects and having the advantage of immediately stopping the medicinal effect in case of emergency.

1 shows that the electronic medicine is used for the treatment of rheumatoid arthritis.

Rheumatoid arthritis, for which no cure has yet been developed, is known to be a disease caused by an autoimmune reaction. Rheumatoid arthritis occurs when immune cells attack the joints and cause inflammation. In 2012, Dr. Kevin Tracy of the United States treated patients with rheumatoid arthritis with electronic medicine. By inserting an electronic drug into the patient's body and applying an electrical signal to the nervous system in charge of the spleen, the generation of cells that control the immune system, such as T cells, was reduced.

Most of the currently developed electronic medicines use primary batteries. When the primary battery is completely discharged, it is necessary to replace the primary battery with a new primary battery, so there is a problem in that the battery is forced to be periodically withdrawn from the human body.

As a prior art for solving this problem, Korea Patent Registration No. 10-2284290, a registered patent by the present applicant, is disclosed. The prior art relates to 'an electronic drug capable of wireless charging for epilepsy treatment and a control method thereof'. The concept of an electronic medicine capable of wireless charging is introduced, and a configuration for preventing electromagnetic wave disturbance generated by a wireless charger during a wireless charging process is disclosed. The configuration of the prior art is significant in that it solves the problems associated with using the primary battery at once.

Secondary batteries can be repeatedly charged and discharged, but cannot be considered permanent.

Therefore, in order to maintain the permanent function of the electronic medicine, it is necessary to have a system that can properly collect bioenergy so that true self-power self-sufficiency is possible, but the size must also be miniaturized, and the development of electronic medicine that maintains stability is urgently needed.

(Patent Document 1) Korea Patent Registration No. 10-2284290

(Patent Document 2) Korean Patent Publication No. 10-2017-0046593

(Patent Document 3) Korean Patent Publication No. 10-2022-0013777

The present invention has been made to solve the above problems, and the present invention has a system capable of properly collecting bioenergy to enable true self-sufficiency of power in order to maintain the permanent function of the electronic medicine, but also miniaturizes the size. and to propose an electronic medicine monitoring system that maintains stability.

In addition, the present invention is to propose an electronic medicine monitoring system that can accurately check the current state information of an electronic medicine implanted in the body in a simple manner.

An embodiment of the present invention for solving the above problems is an electronic medicine monitoring system, which is embedded under the skin and applies a preset electrical stimulation to a nerve; a main power module configured of a secondary battery that provides power to the electronic medicine and is capable of repetitive charging; An energy harvester module configured to generate real-time self-generation using a friction element module, an energy harvester module electrically connected to the main power module and auxiliary charging the main power module; and a control module configured to perform state checking and operation control of the electronic medicine, main power module, and energy harvester module, and having a communication unit capable of wireless communication with a user terminal. Including, it provides an electronic medicine monitoring system.

In addition, the control module may include a first state management unit that manages the state of the main power module and acquires and stores charge/discharge information and remaining capacity information (State Of Charge, SOC) of the main power module; and a second state management unit that manages a state of the energy harvester module and acquires and stores generated power information of the energy harvester module. Including. Information acquired by the first and second state management units may be transmitted to the user terminal through the communication unit.

In addition, the main power module may be configured to receive power wirelessly from an external wireless charging module to enable repetitive charging.

In addition, the control module may include a normal operation determining unit for determining normal operation of the main power module and the energy harvester module; The normal operation determination unit calculates the maximum operation time of the wireless communication between the communication unit and the user terminal in a preset manner using the remaining capacity information of the main power module and the generated power information of the energy harvester module. Normal operation can be judged.

In addition, the electronic medicine monitoring system is an auxiliary power supply unit that assists the main power module, and is composed of a capacitor, and is charged together when the main power module is wirelessly charged or power is supplied to the auxiliary power supply unit when the energy harvester module self-generates. Wired to supply, auxiliary power supply; may further include.

In addition, the first state management unit may control the main power module to receive power from the auxiliary power unit when the sensed remaining capacity information is equal to or less than a preset reference value.

In addition, the control module, a wireless charging operation unit for calculating the wireless charging timing of the main power module and providing it to the user terminal; The wireless charging operation unit determines the wireless charging timing of the main power module by using the power consumption of the main power module, the remaining capacity information of the main power module, and the generated power information of the energy harvester module. can

In addition, the first and second state management units are configured to store all of the acquired information in conjunction with time information, and the wireless charging operation unit consumes power used for electrical stimulation applied from the electronic medicine based on time. And it is possible to determine the wireless charging timing of the main power module by analyzing information on generated power of the energy harvester module according to the user's motion in a preset manner.

In addition, the control module, a. Body temperature information of the user measured by the body temperature sensing unit; me. temperature information of the main power module measured by the battery temperature sensing unit; All. Current information of the energy harvester module measured by the current sensing unit; la. temperature information of an adjacent tissue where the electronic drug is installed, measured by the tissue temperature sensing unit; and e. blood flow information of an adjacent blood vessel in which the electronic drug is installed, measured by the blood flow sensor; It is configured to provide at least one of the following to the user terminal for monitoring, and the body temperature information, the temperature information of the main power module, the current information of the energy harvester module, the temperature information of the adjacent tissue in which the electronic drug is installed, and the adjacent blood vessel in which the electronic drug is installed. If the blood flow information is out of the reference range set for each, it is possible to provide an alarm to the user terminal.

In addition, the control module may include an electrical stimulation setting unit defining an operation for the electrical stimulation of the electronic medicine; The electric stimulation setting unit is set by a manager having prescription authority, and when the user receives a new electronic prescription from the manager, the electric stimulation setting unit includes the strength, cycle, and pattern of the electric stimulation in response to the electronic prescription. The contents of the operation can be updated.

Meanwhile, the present invention provides an electronic medicine monitoring system server, comprising: a communication module; a memory in which an electronic medicine monitoring system program is stored; and a processor that executes the program, and upon execution of the program, when a login request is received from a user terminal, the processor provides a user interface for each of the main power module, the energy harvester module, and the electronic medicine, and provides a user interface to the user. When the user interface for the main power module is selected by the user interface, charging/discharging information and current remaining capacity information of the main power module acquired from the first state management unit are provided, and when the user interface for the energy harvester module is selected by the user , Provides generated power information and power generation efficiency information of the energy harvester module obtained from the second state management unit, and when the user interface for the electronic medicine is selected by the user, the electrical stimulation information obtained from the third state management unit is displayed in chronological order. Provided with, providing a feedback signal of the electrical stimulation applied to the nerve, an electronic medicine monitoring system server.

The effects of the present invention are as follows.

The present invention can have a system capable of appropriately collecting bioenergy to enable self-sufficiency of its own power source in order to maintain the permanent function of the electronic medicine.

In addition, the present invention can monitor the state of the electronic medicine implanted in the body in a simple manner through wireless communication, and can stably perform power management, thereby improving both user convenience and safety.

1 is a prior art, schematically showing a process of performing electrical nerve treatment using an electronic drug.
2 is a conceptual diagram of an electrical neurotherapy system according to a first embodiment of the present invention.
3 is a schematic diagram schematically showing the self-powered principle of the energy harvester module of the electrical neurotherapy system according to the present invention.
Figure 4 is a configuration diagram schematically showing the overall configuration of the electrical neurotherapy system of the present invention.
5 is a conceptual diagram showing the charging method of the main power module of the electrical neurotherapy system according to the present invention by dividing into modes.
6 is a schematic diagram showing the functions of the control module of the electrical neurotherapy system according to the present invention.
7 is a flowchart of a method using the electrical neurotherapy system of the present invention.
8 is a conceptual diagram of an electrical nerve treatment system (second embodiment) to which an energy harvester module according to the present invention is applied.
9 is a configuration diagram showing the configuration of an energy harvester module according to the present invention.
10 is an overall configuration diagram of an electrical neurotherapy system according to a second embodiment.
11 is a schematic schematic diagram of an energy harvester module according to the present invention.
12 is a schematic diagram showing a modified example of the energy harvester module of the present invention.
13 is a schematic diagram of an electrical nerve treatment system to which an energy harvester module according to the present invention is applied.
FIG. 14 shows a cross section of the energy harvester module of FIG. 13 .
15 is a flowchart of a method of using the energy harvester module according to the present invention.
16 is a conceptual diagram of an electronic medicine monitoring system according to the present invention.
17 is a configuration diagram showing the overall configuration of an electronic medicine monitoring system according to the present invention.
18 is a schematic diagram schematically illustrating the functions of the control module of the present invention.
19 is a schematic diagram schematically illustrating a process of determining a wireless charging timing using the control module of the present invention.
20 is a schematic diagram schematically illustrating a process in which a user monitors various information on an electronic medicine using the control module of the present invention.
21 is a schematic diagram schematically showing the application of the electronic medicine monitoring system of the present invention to electronic prescription.
22 is a block diagram showing an electronic medicine monitoring system server according to the present invention.

Hereinafter, various embodiments of the present invention will be described with reference to the accompanying drawings. It should be understood that the present invention is not limited to the specific embodiments, and includes various modifications, equivalents, and/or alternatives of the embodiments of the present invention. In connection with the description of the drawings, like reference numerals may be used for like elements.

In this application, expressions such as “has,” “can have,” “includes,” or “may include” indicate the existence of a corresponding feature (eg, a numerical value, function, operation, or component such as a part). indicated, and does not preclude the presence of additional features.

As used herein, expressions such as "A or B", "at least one of A and/and B", or "one or more of A or/and B" may include all possible combinations of the items listed together. For example, "A or B", "at least one of A and B", or "at least one of A or B" includes (1) at least one A, (2) at least one B, Or (3) may refer to all cases including at least one A and at least one B.

Expressions such as “first,” “second,” “first,” or “second,” as used herein, may modify a variety of elements, regardless of order and/or importance, and may refer to one element as another. It is used to distinguish from elements, but does not limit those elements. For example, a first element may be termed a second element, and similarly, a second element may also be renamed a first element without departing from the scope of rights described herein.

Terms used herein are only used to describe a specific embodiment, and may not be intended to limit the scope of other embodiments. Singular expressions may include plural expressions unless the context clearly dictates otherwise. Terms used herein, including technical or scientific terms, may have the same meaning as commonly understood by one of ordinary skill in the art described herein.

Among the terms used herein, terms defined in a general dictionary may be interpreted as having the same or similar meaning as the meaning in the context of the related art, and unless explicitly defined herein, they are not interpreted in an ideal or excessively formal meaning. don't In some cases, even terms defined herein cannot be interpreted to exclude embodiments of the present application.

Hereinafter, the present invention will be described in detail through the accompanying drawings and examples. A detailed description thereof has been omitted.

In addition, terms to be described later are terms defined in consideration of functions in the present invention, which may vary according to the intention or custom of a user or operator. Therefore, the definition should be made based on the contents throughout this specification.

The present invention is not limited to the rheumatism treatment exemplarily illustrated in FIG. 1 . It is stated in advance that it can be applied to all diseases for which electrical neurotherapy can be performed, such as depressive disorder and Parkinson's disease.

Electrical neurotherapy system equipped with energy harvester module

Hereinafter, the electrical nerve treatment system 100 will be described with reference to FIGS. 2 to 7 .

The electrical nerve treatment system 100 according to the present invention is composed of an electronic medicine 110, a main power module 120, an energy harvester module 130, and a control module 140. Since it is classified based on the function of the individual components, it can be configured in a physically integrated single form.

In other words, the main power module 120 and the energy harvester module 130 of the present invention may be located outside the electronic medicine 110 as well as inside the housing that partitions the electronic medicine 110.

In the present application, for convenience of understanding, configurations are separately described, and the control module 140 is separately described in detail.

The electrical nerve treatment system 100 according to the present invention applies a secondary battery 122 capable of wireless charging and an energy harvester module 130 capable of self-power generation in real time. That is, it is characterized in that the secondary battery 122 and the energy harvester module 130 are used in a hybrid manner.

The electronic drug 110 is embedded under the skin to provide electrical stimulation to nerves. To this end, a second channel line 101 is provided on one side of the electronic drug 110 . The electronic medicine 110 includes a housing forming an exterior and an electrical stimulation generating unit 112 . The second channel line 101 is configured to transmit electrical signals generated by the electrical stimulation generator 112 to nerves.

The electrical stimulation generating unit 112 may include a Printed Circuit Board (PCB). In addition, since the PCB may be disturbed during charging by the wireless charging module 10, a structure and material for shielding electromagnetic waves may be applied. The material may be at least one of a metal such as non-toxic alumina ceramic (Al2O3) or titanium (Ti), a non-toxic acrylic resin, a synthetic resin such as nylon, Teflon, polyurethane, polyester, and silicone.

The main power module 120 includes a secondary battery 122 and a wireless power receiver 124 . As an example of the secondary battery 122, a capacity of 325mAh (nominal 3.6V) may be applied. Various types of secondary batteries may be applied. An optimal shape may be applied depending on the designer's choice, such as a cylindrical, prismatic, or pouch-shaped battery.

As an example, a Vagus Nerve Stimulation (VNS) battery may consume 60 to 100 uWh of power in daily life. The secondary battery 122 is preferably designed with a capacity considering such power consumption.

The main power module 120 includes a wireless power receiver 124. It is configured to receive power wirelessly from an external wireless charging module 10 . At this time, the wireless charging module 10 may be used in a state connected to an external power source, but is not necessarily limited thereto. When the wireless charging module 10 is an energy storage device, it may be configured to wirelessly supply the electrical energy stored in the wireless charging module 10 without being connected to an external power source (plug).

Inside the housing of the electronic medicine 110, the wireless power receiver 124 is provided inside a partition-shaped inner shield (not shown), so it is preferable to be isolated from other elements.

The energy harvester module 130 is configured to self-generate in real time using a friction element module. Since the energy harvester module 130 is an element inserted into the user's body, a predetermined vibration (or external force) may also be applied to the energy harvester module 130 when the user's movement occurs.

The principle of the energy harvester module 130 is as shown in FIG. 3 .

The friction element module 132 may refer to the layer assembly form shown in FIG. 3 . The friction element module 132 generates nonlinear electric energy by using the friction element. Such a friction element may be a triboelectric nano-generator (TENG).

The harvester unit 134 may be configured to sequentially store the nonlinear electric energy generated through the friction element module 132 in a multi-stage energy storage (not shown) and supply the energy stored in the energy storage. At this time, the energy storage has a different configuration from the battery, and means an energy storage having a small energy storage space integrally formed with an electronic circuit.

Referring to FIG. 3 , when different layers are in contact, a phenomenon in which a surface is charged by frictional electrification occurs. The present invention can be performed through multiple layers. Hereinafter, for convenience of description, an example of double layered will be described, but this is a concept that can be applied to all multi-layers.

Specifically, when the two layers are separated, compensation charges are accumulated in the upper and lower electrodes by an electrostatic induction phenomenon, and thus current flows through the external electrodes until the charges are balanced. When the two materials get closer again, the accumulated compensation charge disappears, so the current in the opposite direction to the first one flows through the external electrode, and alternating current continuously flows between the two electrodes through repeated contact and separation processes. It is a principle.

The energy harvester module 130 is electrically connected to the main power module 120 and is configured to auxiliary charge the main power module 120 . The secondary battery 122 of the main power module 120 may be charged in a hybrid manner by the wireless charging module 10 and the energy harvester module 130 .

As an example, the energy harvester module 130 may be configured to generate energy of 20uWh (based on a harvester size of 100mm2) and is designed with a capacity capable of compensating for 20 to 30% of the power consumed by the secondary battery 122 at all times. It can be. This means that it is designed with a capacity of about 2% based on the capacity of the secondary battery 122 .

Since the main power module 120 mainly receives power from the external wireless charging module 10, the energy harvester module 130 serves to auxiliary charge the main power module 120. Although the power supply of the energy harvester module 130 is relatively small, it has a great effect in that it can continuously produce and supply electrical energy in response to the user's movement.

Hereinafter, the control of the main power module 120 and the energy harvester module 130 by the control module 140 will be described in detail with reference to FIGS. 4 to 7 .

The control module 140 controls charging of the main power module 120 and the energy harvester module 130 .

It will be described with reference to FIG. 5 first. Based on the main power module 120, the 'first charging mode' in which the main power module 120 receives power from the energy harvester module 130 and the main power module 120 receives power from the wireless charging module 10 It is divided into a 'second charging mode' supplied with .

Here, the first and second charging modes are preferably operated alternatively to each other. That is, the main power module 120 may be configured not to be simultaneously charged by the energy harvester module 130 and the wireless charging module 10 . Considering charging efficiency and capacity, charging by the wireless charging module 10 can generally receive more power, so the second charging mode can be set to take precedence over the first charging mode.

The electrical stimulation generating unit 112 of the electronic medicine 110 may perform a 'discharge mode' while generating an electrical stimulation signal. The discharge mode means that electrical energy of the main power module 120 or the energy harvester module 130 is consumed.

Since it is efficient that the energy harvester module 130 is configured to be able to be charged at all times, it is preferable to be set to be able to simultaneously perform the discharging mode during the first charging mode operation. On the other hand, when the second charging mode operates, it is preferable to operate in the discharging stop mode, and when the second charging mode ends (meaning that the wireless charging by the wireless charging module 10 is finished), it is automatically discharged again. It can be set to run in mode.

This is to prevent electrical interference from occurring in stable wireless charging and generation of electrical stimulation signals from the electrical stimulation generating unit 112 . This is because the second channel line 114 connected to the electrical stimulation generating unit 112 directly contacts and connects to nerves in the body, and even when minute electrical interference occurs, it may adversely affect the user.

However, the charging mode operation may be designed to operate simultaneously according to a designer's choice. That is, even while the second charging mode by the wireless charging module 10 is operated, it means that the first charging mode can be simultaneously operated by the user's movement. In this case, in order to maintain stable charging by the wireless charging module 10, a separate holding means (or fixing means) may be used. The mounting means is configured in the form of a band having a predetermined elasticity, so that the wireless charging module 10 can be kept in close contact with the body. Accordingly, even when there is a user's movement, the second charging mode can be continuously performed without interruption.

That is, the present invention is a system capable of safely and stably supplying power even when the wireless charging module 10 and the energy harvester module 130 are connected together.

Detailed functions of the control module 140 will be described with reference to FIGS. 4 and 6 .

The control module 140 includes a body temperature sensing unit 141, a battery temperature sensing unit 142, a current sensing unit 143, a BMS unit 144 and a vibration sensor unit 145. Each of them is configured to sense information to be collected according to a preset period or condition.

That is, the control module 140 quantifies the user's body temperature information, the temperature information of the main power module 120 (preferably the secondary battery 122), the current information of the energy harvester module 130, and the user's movement. It is configured to collect vibration information, which is a value. Each of these is configured to have a preset reference value, and the control module 140 instructs the energy harvester module 130 to stop the charging operation when the collected values are greater than or equal to each reference value. That is, the first charging mode is forcibly stopped.

If the above reference value is exceeded, there is a possibility of an error or failure of the energy harvester module 130. To protect the user's body, the energy harvester module 130 is forcibly stopped.

For example, when the body temperature information is greater than or equal to the reference value, there is a risk of damage to body tissue adjacent to the location where the energy harvester module 130 is installed. This is because it can cause deformation or destruction of body tissues composed of proteins. The temperature information of the main power module 120 and the current information of the energy harvester module 130 are also for the same reason.

The vibration sensor unit 145 is configured to detect vibration (or movement) of the user's body. This is linked to the user's physical activity. For example, when the user is sleeping, the vibration may be relatively low, but when the user is outdoors, the vibration may be relatively high, and power generation by the energy harvester module 130 may be actively performed.

If, while the user is charging through the wireless charging module 10, when the vibration value is greater than the reference value, the user may be guided to stop the operation of the second charging mode by the wireless charging module 10. This notification may be provided through the user terminal 20 .

The wireless charging module 10 can be charged while wearing a separate body fixing device for stable charging (second charging mode), so even when the second charging mode is being performed, the user can exercise actively can do.

Meanwhile, the control module 140 may include a BMS unit 144. The BMS unit 144 may be provided in each of the main power module 120 and the energy harvester module 130, but in the present application, for convenience of explanation, it is defined that the control module 140 includes the BMS unit 144. did

The BMS unit 144 monitors the states of the main power module 120 and the energy harvester module 130 . In particular, it is configured to acquire charge/discharge information and remaining capacity information (State Of Charge, SOC) of the main power module 120 and transmit it to the user terminal 20 .

The user can check the current state of the main power module 120 through the user terminal 20, predict when wireless charging is required, the remaining use time of the electronic medicine 110, and the like.

In addition, the BMS unit 144 may be configured to detect an electrical connection state between the external wireless charging module 10 and the main power module 120, and provide the electrical connection state and real-time charging information to a user terminal. This is because the wireless power supply unit (not shown) of the wireless charging module 10 and the wireless power receiver 124 of the main power module 120 need to be positioned so as to correspond to each other due to the characteristics of wireless charging.

If they are not positioned, it is necessary to inform the user and force the user to place them.

In addition, the BMS unit 144 may induce charging by the energy harvester module 130 when the remaining capacity information of the main power module 120 falls below a reference value. When it is difficult to use the wireless charging module 10, charging by the energy harvester module 130 is induced by inducing a user's movement. The electric nerve treatment system according to the present invention uses the main power module 120 and the energy harvester module 130 in a hybrid manner, and the above alarm can be very useful.

Referring to FIG. 7 , a method using the electrical neurotherapy system according to the present invention will be described. A description overlapping with the foregoing content will be omitted.

The method may consist of steps S110 to S130.

Step S110 is a step in which the discharge mode of the main power module 120 is performed while applying a predetermined electric stimulus from the electronic medicine 110 to the user's nerve.

Step S120 is a step in which vibration is applied to the energy harvester module 130 to perform self-power generation, and a first charging mode for charging the main power module 120 is performed. As vibrations are naturally applied to the friction element module 132 during a user's daily life, nonlinear electrical energy is produced.

Of course, the first charging mode may be performed simultaneously with the discharging mode of step S110.

In step S130, when the remaining capacity information of the main power module 120 falls below a preset reference value, a second charging mode in which power is wirelessly supplied from an external wireless charging module is performed. Here, when the second charging mode is performed, it may be operated in a discharge stop mode in which power supply from the main power module 120 to the electronic medicine is stopped.

Energy harvester module connected to the outside of electronic medicine

Hereinafter, an energy harvester module according to the present invention will be described with reference to FIGS. 8 to 15 . The energy harvester module 130 to be described below may be classified as another embodiment of the electrical nerve treatment system described above. The above-described embodiment has been described on the premise of a structure in which the energy harvester module 200 is located in the housing of the electronic medicine 110, but in another embodiment described below, the energy harvester module 230 is outside the electronic medicine 210 It is a structure that is located independently of

Redundant description of the aforementioned individual components will be omitted.

Referring to FIG. 8 , the energy harvester module 230 may be distinguished from the first embodiment in that it is located outside the electronic drug 210 . That is, when the life of the energy harvester module 230 ends or replacement is required, it is a structure in which only the energy harvester module 230 can be replaced and used separately from the electronic medicine 210 .

For reference, a control module 240 and a main power module 220 are provided inside the housing of the electronic medicine 210 .

The energy harvester module 230 includes a generator 233 , a harvester unit 235 and a case 231 .

The case 231 forms the exterior of the energy harvester module 230 and protects internal components. In order to protect the inside from a strong external force, it is preferably formed of a titanium material. A feed-through 236 is formed on one side of the case 231, and a first channel line 237 extends in the direction of the electronic medicine 210 through the feed-through 236.

The generator 233 uses the friction element module 232 to generate nonlinear electrical energy. The principle of generating electric energy using the internal friction element module 232 is as described in FIG. 3 .

As the friction element module 232, any known element capable of generating triboelectricity may be used. Examples of devices applicable to the present invention are as follows. This is a simple example, but is not limited thereto.

1) ZnO nanorods@conductive carbon black nanocomposite based flexible triboelectric energy conversion and storage integrated system, nanogenerator and supercapacitor;

2) Co/Zn bimetallic organic framework ellipsoidal nanosheets in flexible conducting fabrics for energy harvesting and environmental monitoring via triboelectricity;

3) High-performance triboelectric nanogenerator based on double-layered electrode effect;

4) Combining triboelectric and thermoelectric, hybrid nanogenerators (sliding) through triboelectricity for advanced smart sensors;

The harvester unit 235 is a component that temporarily stores electrical energy provided from the generator 233 in a preset manner. The nonlinear electrical energy generated through the friction element module 232 of the generator 233 is sequentially stored in the multiple energy storage units 235a, 235b, and 235c configured in multiple stages, and stored in the multiple energy storage units 235a, 235b, and 235c. supplies energy At this time, the multi-energy storage 220 has a different configuration from a battery (or battery), and means an energy storage having a small energy storage space integrated with an electronic circuit. The harvester unit 235 shown in FIG. 9 is an exemplary structure, and the number of multiple energy storage units 235a, 235b, and 235c may be optimally designed according to a designer's choice.

Since the harvester unit 235 is connected to the first channel line 237, electrical energy can be provided to the side of the electronic medicine 210 in real time through the first channel line 237.

Referring to FIG. 10 , the electronic drug 210 is provided with a second channel line 202 contacting a target nerve (referred to as 'vagus nerve' in FIG. 3 exemplarily). Electrical energy provided from the energy harvester module 230 may be provided to nerves in the user's body via the secondary battery 222 and the second channel line 202 .

The first channel line 237 may be connected through the connector unit 226 . Based on the connector unit 226, the portion connected to the electronic drug 210 is referred to as a first channel line A (237a), and the portion connected to the energy harvester module 230 is divided into a first channel line B (237b). .

The first channel line A 237a and the first channel line B 237b are interconnected through a connector unit 226 . In this way, as the connector unit 226 is provided, replacement of the energy harvester module 230 may be facilitated.

10 shows a modified example of the energy harvester module 230. Electrical energy is not only supplied through the first channel line A 237a and the first channel line B 237b, but also shows a configuration in which a wireless charging method is possible.

To this end, the energy harvester module 230 may include a wireless power transmitter 238, and a wireless power receiver 224 may be provided on the side of the electronic medicine 210. Here, the wireless power receiver 224 on the side of the electronic medicine 210 is preferably used in combination with the external wireless charging module 10. Unlike charging by the wireless charging module 10, wireless charging by the energy harvester module 230 is distinguished in that it is always charging. Of course, charging conditions, methods and cycles may be set according to the manager's choice.

The secondary battery 222 of the electronic medicine 210 may be connected to the capacitor unit 226 . Compared to the secondary battery 222, the capacitor unit 226 may not have a relatively large charge capacity. Since the capacitor unit 226 physically adsorbs electrons even if the charging capacity is not very large, it can be stably used inside the living body without structural change. In addition, since electrons can be emitted in a very fast time, it can be applied to high power, so it can be used very effectively as an alternative power source or auxiliary power source for the electronic medicine 210.

11 schematically shows a generator 233 equipped with an amplifying damper 233c.

The amplifying damper 233c is coupled to a pre-calculated position, and is formed to sustain the minute movement of the friction element in consideration of the user's movement. As shown in FIG. 11, it may be formed on the outermost layer of the friction element module, and may be formed in plural numbers, but may be formed in a size corresponding to a certain interval.

People are normally active through various movements, and by these movements in daily life, the generator 233 to which the amplification damper 233c is attached generates electricity, and even while the movement occurs or at the moment when the movement stops The amplification damper 233c can maximize the power generation characteristics by continuing the minute movement of the friction element in the spaced apart space.

As shown in FIG. 11, the generator 233 may be composed of multi-layers. An example of a dual layer, which is the most basic of multi-layers, will be described.

The multi-layer dual layer of FIG. 11 is divided into a first layer 233a and a second layer 233b. Electric energy is generated by friction when the first and second layers 233a and 233b come into contact.

Referring to Figure 12, it shows the arrangement of the generator considering the movement of the user. The form shown in FIG. 12 takes into consideration the user's life pattern, and in the case of a frequent walker, it is desirable to provide a generator arrangement form optimized for a walking motion.

That is, by matching the direction in which the external force is mainly applied (meaning the direction of the force) and the arrangement direction of the multi-layers 233a and 233b in the generator 233, the applied external force is the friction of the multi-layers 233a and 233b. to be used to its fullest extent.

This inclination angle θ may be calculated based on the user's stride length. This is because the user's stride length affects the inclination of the user's body when the user is walking. Since each user has a different physical condition and a different stride length, the administrator can set an inclination angle θ optimized for the user.

Also, the area of the multi-layer may be determined in consideration of the user's movement frequency and time. In the case of a user who moves a lot, even if the area of the multi-layer is formed relatively small, it is possible to sufficiently secure the desired charging capacity. In the case of a user with little movement, the friction area can be increased by forming a large area of the multi-layer. The area of the multi-layer may be performed by adjusting the length (l) and the width (d).

The inclination angle (θ) and the area of the layer are preferably set to values optimized for the user by obtaining the user's walking characteristics and behavioral characteristics data through a smart watch or the like.

13 is a schematic diagram of an electrical nerve treatment system to which an energy harvester module according to the present invention is applied. It matches the conceptual diagram shown in FIG. 3 .

The electronic medicine 210 is formed such that two channel lines are coupled. It is composed of a first channel line 237 connected to the energy harvester module 230 and a second channel line 202 coupled to a nerve. The tip 202a of the second channel line 202 is in contact with a nerve region.

The form shown in FIG. 13 shows an exemplary form of the electronic medicine 210 as well as the energy harvester module 230 according to the present invention, and may be designed in other forms and sizes. The shape of the energy harvester module 230 may also be formed in a circular shape based on a plane.

Referring to FIG. 14, a modified example of the multi-layer 230' will be described. The modified example shown in FIG. 14 is a structure in which directionality is given to mutually facing sides (meaning frictional sides). A plurality of unit friction elements 239a and 239b are formed on the facing surfaces, respectively.

The unit friction elements 239a and 239b formed on each of the upper first layer 233a and the second layer 233b have shapes corresponding to each other. The unit friction elements 239a and 239b are formed to have a predetermined inclination. This can be viewed as the same concept as the inclination angle θ described above. The angle of inclination of the unit friction elements 239a and 239b is designed in consideration of the angle of the user's body. The length (a), number, position, and spacing of the unit friction elements 239a and 239b may be configured in a form optimized for the user according to a designer's choice.

Here, the remaining distance (b) between the multi-layer 230' and the case 231 considers the hypotenuse lengths of the unit friction elements 239a and 239b. That is, it is preferable that the remaining distance (b) is formed leisurely enough not to interfere with sliding.

Electronic medicine monitoring system

Hereinafter, the electronic medicine monitoring system 300 according to the present invention will be described with reference to FIGS. 16 to 22 . Redundant descriptions of the above detailed configurations will be omitted.

The electronic medicine monitoring system 300 is composed of an electronic medicine 310, a main power module 320, an energy harvester module 330, and a control module 340.

The control module 340 checks the status of the electronic drug 310, the main power module 320, and the energy harvester module 330 and performs operation control. In addition, a communication unit 341 capable of wireless communication with the user terminal 20 is provided. The communication unit 341 is connected wirelessly/wired to the network and is configured to transmit the obtained information to the user terminal 20 .

In relation to the wireless communication of the present invention, the present invention provides PCS (Personal Communication System), GSM (Global System for Mobile communications), PDC (Personal Digital Cellular), PHS (Personal Handyphone System), PDA (Personal Digital Assistant), IMT ( International Mobile Telecommunication)-2000, CDMA(Code Division Multiple Access)-2000, W-CDMA(W-Code Division Multiple Access), Wibro(Wireless Broadband Internet) terminal, smartphone, smartpad, tablet All kinds of handheld-based wireless communication devices such as PCs (Tablet PCs), and computing devices such as stationary PCs and notebooks can be used, and the distributed applications are implemented in the form of computer programs and can read and write. It can be recorded on an available recording medium and mounted on a terminal.

In addition, since the system according to the present invention is based on a network, the network means a connection structure capable of exchanging information between nodes such as terminals and servers. Examples of such networks include a 3rd Generation Partnership Project (3GPP) network, a Long Term Evolution (LTE) network, a World Interoperability for Microwave Access (WIMAX) network, the Internet, a Local Area Network (LAN), and a Wireless LAN. (Wireless Local Area Network), WAN (Wide Area Network), PAN (Personal Area Network), Bluetooth network, satellite broadcasting network, analog broadcasting network, DMB (Digital Multimedia Broadcasting) network, WiFi, etc. Not limited.

Referring to FIG. 16 , the present invention is characterized in that the information obtained through the control module 340 is transmitted to the user terminal 20 . The communication unit 341 may also be configured as a transceiver capable of bi-directional communication.

Referring to FIG. 17 , the secondary battery 322 of the main power module 320 may be connected to the auxiliary power unit 324 to receive power. The auxiliary power supply unit 324 includes a capacitor. As a modified example, the auxiliary power supply unit 324 may be connected to the communication unit 341. At this time, the communication unit 341 is composed of a commercial Bluetooth Low Energy (BLE) board may be configured to perform short-range communication with the user terminal 20.

Referring to FIG. 18, the control module 340 of the present invention will be described.

The control module 340 includes a first state management unit 342, a second state management unit 343, a normal operation determination unit 344 and a wireless charging operation unit 345, all of which are connected to the communication unit 341 to mutually It is configured to exchange information.

The first state management unit 342 manages the state of the main power module 320, and is configured to acquire and store charge/discharge information and remaining capacity information (State Of Charge, SOC) of the main power module 320. The state of the main power module 320 is a broad concept meaning all states of the secondary battery 322 included in the main power module 320 .

As an example, the first state management unit 342 may control the main power module 320 to receive power from the auxiliary power unit 324 when the sensed remaining capacity information is equal to or less than a preset reference value. To this end, it is preferable that the remaining capacity information of the auxiliary power unit 324 is also designed to be checked in real time by the first state management unit 342 .

The second state management unit 343 manages the state of the energy harvester module 330, and is configured to acquire and store generated power information of the energy harvester module 330. The energy harvester module 330 performs self-power generation by the user's movement, and the history of self-power generation is automatically stored. Conversely, through the second state management unit 343, it is possible to inversely estimate the motion of the user.

The normal operation determining unit 344 determines normal operation of the main power module 320 and the energy harvester module 330 . Information on the normal operation of the main power module 320 and the energy harvester module 330 is predefined in the control module 340 .

Since the present invention includes an electronic medicine that applies an electrical signal to a user's nerve, it is a very important function to determine normal operation in order to protect the user's body and prevent accidents.

As an example of determining the normal operation, using the remaining capacity information of the main power module 320 and the generated power information of the energy harvester module 330, the communication unit 341 and the user terminal 20 in a preset manner. There is one that determines normal operation by calculating the maximum operation time of wireless communication.

Although the remaining capacity information of the main power module 320 and the generated power information of the energy harvester module 330 are sufficient, the maximum operating time of wireless communication between the communication unit 341 and the user terminal 20 is calculated as a significantly low value. If so, it can be judged as 'abnormal'. This may mean that a lot of power is consumed in elements other than the main power module 320 and the energy harvester module 330, or it may be in a state where accurate information transmission and reception is impossible due to a wireless communication error.

It is important to immediately solve these problems, but it is also very important to promptly provide the user with whether or not they are operating normally. In the case of 'abnormal', the user immediately forcibly stops the operation of the electronic medicine 310.

The control module 340 further includes a wireless charging calculator 345 that calculates the wireless charging timing of the main power module 320 and provides it to the user terminal 20 .

The remaining capacity information of the electronic medicine 310 of the present invention is the most important information for protecting the user's body. This is because it is directly related to the normal operation of the electronic medicine 310.

Referring to FIG. 19 , the wireless charging operation unit 345 receives corresponding information from the main power module 320 and the energy harvester module 330, respectively. It is desirable to receive real-time information, but a predetermined period and conditions may be set.

The wireless charging timing of the main power module 320 is determined using the power consumption of the main power module 320, the remaining capacity information of the main power module 320, and the generated power information of the energy harvester module 330.

19 shows an exemplary method.

The wireless charging operation unit 345 calculates the 'primary expected usable time' based on the remaining capacity information of the current main power module 320 . Then, based on the 'primary expected usable time', the expected generated power information of the energy harvester module 330 is calculated, and based on this, the second expected usable time is determined.

If the second expected usable time is equal to or less than a predetermined value, it is judged whether the power saving mode is necessary. It is preferable that the power save mode is set by a user's selection. This is because it is important for the user to recognize that the power save mode is currently being performed.

To this end, the first and second state management units 342 and 343 may be configured to store all of the acquired information in conjunction with time information.

At this time, the wireless charging operation unit 345 determines the power consumption used for the electrical stimulation applied from the electronic medicine 310 and the generated power information of the energy harvester module 330 according to the user's movement on the basis of time in a preset manner. By analyzing, it is possible to determine the wireless charging timing of the main power module 320.

That is, based on the past use history, it means determining the wireless charging timing of the main power module 320. Based on 24 hours per day, it is predicted based on the statistics of power consumption and generated power information used for electrical stimulation at a specific time. As the prediction method, statistical techniques such as regression analysis may be used.

Referring to FIG. 20 , detailed information collected by the control module 410 of the present invention can be seen. These detailed information is configured to be confirmed in the user terminal (20). If the user terminal 20 is a smart phone/smart tablet, it can be confirmed through an installed application.

The control module 410 includes a body temperature sensing unit 340a, a battery temperature sensing unit 340b, a current sensing unit 340c, a tissue temperature sensing unit 340d, a blood flow sensing unit 340e, and a feedback signal sensing unit 340f. receive that information from

Specifically, the user's body temperature information measured by the body temperature sensing unit 340a, the temperature information of the main power module 320 measured by the battery temperature sensing unit 340b, and the energy measured by the current sensing unit 340c Current information of the harvester module 330, temperature information of the adjacent tissue where the electronic drug 310 is installed measured by the tissue temperature sensing unit 340d, and the electronic drug 310 measured by the blood flow sensor 330e are installed It is configured to provide the user terminal 20 with blood flow information of adjacent blood vessels.

In addition, the control module 340 may be configured to analyze a feedback signal for the electrical signal applied to the electrical stimulation generating unit 312 . Through the analysis of such a feedback signal, it is possible to check not only whether or not a nerve is damaged, but also the transmission state of an electrical signal.

As a modified example of the present invention, the control module 340 may further include an electrical stimulation setting unit 347. The electrical stimulation setting unit 347 is a component related to electronic prescriptions in medical institutions.

The electric signal of the electronic medicine 310 may be composed of various elements such as strength, pattern, and type. We can call this a 'dataset'. These datasets can only be set up by administrators (experts) with prescribing rights. This is because the act of treating through the electronic medicine 310 can be included within the scope of medical practice.

Medical treatment and electronic prescription may be performed remotely through the user terminal 20 . When the user receives a new electronic prescription from the administrator, operation details including strength, cycle, and pattern of the electrical stimulation are updated in response to the electronic prescription. That is, a new data set is created, and the electrical stimulation generator 312 is configured to apply an electrical signal according to the contents of the new data set.

Referring to FIG. 22, the present invention provides a configuration for communicating through a user terminal 20 and a server. As described above, it may be performed through an application installed in the user terminal 20 .

Specifically, when a log-in request is received from the user terminal 20, user interfaces for each of the main power module 320, the energy harvester module 330, and the electronic medicine 310 are provided. The user can select any one of them, and can check status information on the selected item in real time.

First, when the user interface for the main power module 320 is selected by the user, charge/discharge information and current remaining capacity information of the main power module 320 obtained from the first state management unit 342 are provided.

When the user interface for the energy harvester module 330 is selected by the user, generated power information and generation efficiency information of the energy harvester module 330 acquired from the second state management unit 343 are provided.

When the user interface for the electronic drug 310 is selected by the user, the electrical stimulation information obtained from the third state management unit 344 is provided in chronological order, and a feedback signal of the electrical stimulation applied to the nerve is provided. That is, it means providing history information on electrical stimulation.

The above embodiment in the present invention is an example, and the present invention is not limited thereto. Anything that has substantially the same configuration as the technical concept described in the claims of the present invention and achieves the same effect is included in the technical scope of the present invention.

10: wireless charging module
20: user terminal
110, 210, 310: electronic medicine
120, 220, 320: main power module
122, 222, 322: secondary battery
130, 230, 330: energy harvest module
140, 240, 340: control module

Claims (11)

As an electronic medicine monitoring system,
An electronic drug embedded under the skin and applying a preset electrical stimulation to a nerve;
a main power module configured of a secondary battery that provides power to the electronic medicine and is capable of repetitive charging;
An energy harvester module configured to generate real-time self-generation using a friction element module, an energy harvester module electrically connected to the main power module and auxiliary charging the main power module; and
A control module, which checks the state of the electronic medicine, the main power module, and the energy harvester module and controls the operation, and is equipped with a communication unit capable of wireless communication with a user terminal;
The energy harvester module,
A generator for generating electrical energy using the friction element module,
the generator,
Composed of multi-layers, at least some of which have a predetermined inclination,
Electronic medicine monitoring system.
The method of claim 1,
The control module,
a first state management unit that manages the state of the main power module, obtains and stores charge/discharge information and remaining capacity information (State Of Charge, SOC) of the main power module; and
a second state management unit that manages a state of the energy harvester module and acquires and stores generated power information of the energy harvester module; Including,
The information obtained by the first and second state management units is transmitted to the user terminal through the communication unit.
Electronic medicine monitoring system.
The method of claim 2,
The main power module,
Formed to receive power wirelessly from an external wireless charging module and enable repetitive charging,
Electronic medicine monitoring system.
The method of claim 3,
The control module,
a normal operation determining unit for determining normal operation of the main power module and the energy harvester module; Including more,
The normal operation determination unit,
Using the remaining capacity information of the main power module and the generated power information of the energy harvester module, calculating the maximum operating time of wireless communication between the communication unit and the user terminal in a preset manner to determine normal operation,
Electronic medicine monitoring system.
The method of claim 3,
The electronic medicine monitoring system,
an auxiliary power unit configured of a capacitor and connected to supply power to the auxiliary power unit when the main power module is wirelessly charged or when the energy harvester module self-generates; Including more,
Electronic medicine monitoring system.
The method of claim 5,
The first state management unit,
Controlling the main power module to receive power from the auxiliary power unit when the sensed remaining capacity information is less than a preset reference value,
Electronic medicine monitoring system.
The method of claim 3,
The control module,
a wireless charging operation unit that calculates a wireless charging timing of the main power module and provides it to a user terminal; Including more,
The wireless charging operation unit
Determining the wireless charging timing of the main power module using the power consumption of the main power module, the remaining capacity information of the main power module, and the generated power information of the energy harvester module,
Electronic medicine monitoring system.
The method of claim 7,
The first and second state management units,
It is configured to store all the acquired information in conjunction with time information,
The wireless charging operation unit
Based on time, the power consumption used for the electrical stimulation applied from the electronic medicine and the power information generated by the energy harvester module according to the user's movement are analyzed in a preset manner to determine the wireless charging timing of the main power module. doing,
Electronic medicine monitoring system.
The method of claim 1,
The control module,
go. Body temperature information of the user measured by the body temperature sensing unit;
me. temperature information of the main power module measured by the battery temperature sensing unit;
All. Current information of the energy harvester module measured by the current sensing unit;
la. temperature information of an adjacent tissue where the electronic drug is installed, measured by the tissue temperature sensing unit; and
mind. blood flow information of an adjacent blood vessel in which the electronic drug is installed, measured by the blood flow sensor; It is configured to provide at least one of them to a user terminal for monitoring,
When the body temperature information, the temperature information of the main power module, the current information of the energy harvester module, the temperature information of the adjacent tissue in which the electronic drug is installed, and the blood flow information of the adjacent blood vessel in which the electronic drug is installed are out of the respective set reference ranges, the user terminal to provide an alarm with
Electronic medicine monitoring system.
The method of claim 1,
The control module,
an electrical stimulation setting unit defining an operation of the electronic medicine in response to electrical stimulation; Including more,
The electrical stimulation setting unit,
It is set by an administrator with prescription authority,
When the user receives a new electronic prescription from the manager, the operation contents including the intensity, cycle, and pattern of the electrical stimulation are updated in response to the electronic prescription.
Electronic medicine monitoring system.
In the electronic medicine monitoring system server,
communication module;
a memory in which an electronic medicine monitoring system program is stored;
A processor that executes the program;
According to the execution of the program, the processor,
When a login request is received from the user terminal, a user interface for each of the main power module, energy harvester module, and electronic medicine is provided,
When a user interface for the main power module is selected by the user, charging/discharging information and current remaining capacity information of the main power module obtained from a first state management unit are provided;
When a user interface for an energy harvester module is selected by a user, generating power information and power generation efficiency information of the energy harvester module obtained from a second state management unit are provided;
When the user interface for the electronic medicine is selected by the user, electrical stimulation information obtained from the third state management unit is provided in chronological order, and a feedback signal of the electrical stimulation applied to the nerve is provided;
The energy harvester module,
Including a generator that generates electrical energy using a friction element module,
the generator,
Composed of multi-layers, at least some of which have a predetermined inclination,
Electronic medicine monitoring system server.

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