KR20200142537A - 비-뉴런 세포의 뉴런으로의 리프로그래밍 및 신경퇴행성 질환 및 장애를 치료하기 위한 방법 및 조성물 - Google Patents

비-뉴런 세포의 뉴런으로의 리프로그래밍 및 신경퇴행성 질환 및 장애를 치료하기 위한 방법 및 조성물 Download PDF

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KR20200142537A
KR20200142537A KR1020207032064A KR20207032064A KR20200142537A KR 20200142537 A KR20200142537 A KR 20200142537A KR 1020207032064 A KR1020207032064 A KR 1020207032064A KR 20207032064 A KR20207032064 A KR 20207032064A KR 20200142537 A KR20200142537 A KR 20200142537A
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cell
ptb
cells
neurons
astrocytes
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샹-동 푸
하오 치안
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더 리젠츠 오브 더 유니버시티 오브 캘리포니아
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KR1020207032064A 2018-04-11 2019-04-11 비-뉴런 세포의 뉴런으로의 리프로그래밍 및 신경퇴행성 질환 및 장애를 치료하기 위한 방법 및 조성물 Ceased KR20200142537A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862656322P 2018-04-11 2018-04-11
US62/656,322 2018-04-11
US201862718774P 2018-08-14 2018-08-14
US62/718,774 2018-08-14
PCT/US2019/027027 WO2019200129A1 (en) 2018-04-11 2019-04-11 Reprogramming of non-neuronal cells into neurons and methods and compositions to treat neurodegenerative diseases and disorders

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KR20200142537A true KR20200142537A (ko) 2020-12-22

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KR1020207032064A Ceased KR20200142537A (ko) 2018-04-11 2019-04-11 비-뉴런 세포의 뉴런으로의 리프로그래밍 및 신경퇴행성 질환 및 장애를 치료하기 위한 방법 및 조성물

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US (2) US11702656B2 (https=)
EP (1) EP3773749A4 (https=)
JP (1) JP2021520200A (https=)
KR (1) KR20200142537A (https=)
CN (1) CN112312928A (https=)
AU (1) AU2019252534A1 (https=)
CA (1) CA3096691A1 (https=)
GB (2) GB202017810D0 (https=)
WO (1) WO2019200129A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023068826A1 (ko) * 2021-10-20 2023-04-27 서울시립대학교 산학협력단 자가조립된 rna 구조체를 포함하는 직접교차분화 유도용 조성물

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JP2022543722A (ja) * 2019-08-16 2022-10-14 センター フォー エクセレンス イン ブレイン サイエンス アンド インテリジェンス テクノロジー，チャイニーズ アカデミー オブ サイエンシーズ 機能的ニューロン死に関連する神経系疾患の予防および／または治療におけるＰｔｂｐ１阻害剤の使用
CN112386699A (zh) * 2019-08-16 2021-02-23 中国科学院脑科学与智能技术卓越创新中心 Ptbp1抑制剂在预防和/或治疗功能性神经元死亡相关的神经系统疾病中的应用
US20230242873A1 (en) * 2020-05-13 2023-08-03 Figene, Llc Fibroblast based therapy for treatment of parkinson's disease
US20240050589A1 (en) * 2020-12-25 2024-02-15 Shanghai Genemagic Biosciences Co., Ltd. Treatment of neurological diseases
CN112661828B (zh) * 2021-01-15 2022-04-01 武汉大学 一种突触素的抗原肽及其抗体与应用
CN117279668A (zh) * 2021-02-10 2023-12-22 上海鲸奇生物科技有限公司 胶质细胞向神经元转分化用于预防或治疗神经元功能缺失或死亡相关疾病
CN112941019B (zh) * 2021-03-18 2023-01-06 浙江大学 一种促进体细胞重编程的方法
CN116144596A (zh) * 2021-03-26 2023-05-23 广西大学 一种体外高效诱导人体细胞重编程为神经元细胞的方法
CN113171369A (zh) * 2021-04-16 2021-07-27 南通大学 多聚嘧啶序列结合蛋白在制备脊髓损伤的修复药物中的应用
WO2022222974A1 (zh) * 2021-04-21 2022-10-27 上海跃赛生物科技有限公司 一种质控和富集人多巴胺能神经前体细胞的方法
CN120754249A (zh) * 2021-09-30 2025-10-10 上海鲸奇生物科技有限公司 直接转分化治疗神经系统疾病

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US9057053B2 (en) 2010-01-19 2015-06-16 The Board Of Trustees Of The Leland Stanford Junior University Direct conversion of cells to cells of other lineages
US9206426B2 (en) * 2010-03-05 2015-12-08 The Trustees Of Columbia University In The City Of New York Inhibitory RNAs to RNA binding proteins hnRNPA1, hnRNPA2 and PTB and uses thereof
US20140051085A1 (en) 2011-03-01 2014-02-20 The Scripps Research Institute Direct reprogramming of human fibroblasts to functional neurons under defined conditions
US10561742B2 (en) * 2012-07-19 2020-02-18 The Penn State Research Foundation Methods and compositions for treatment of disease or injury of the nervous system
WO2014071157A1 (en) * 2012-11-01 2014-05-08 The Regents Of The University Of California Methods for engineering non-neuronal cells into neurons and using newly engineered neurons to treat neurodegenerative diseases
US9730975B2 (en) * 2014-11-25 2017-08-15 The Penn State Research Foundation Chemical reprogramming of human glial cells into neurons for brain and spinal cord repair
WO2017003466A1 (en) * 2015-06-30 2017-01-05 University Of South Florida Conversion of non-neuronal cells into neurons
US20180318260A1 (en) * 2015-11-04 2018-11-08 The Scripps Research Institute Compositions and methods for treating cystic fibrosis
CN105950557B (zh) * 2016-04-22 2019-10-25 中国科学院生物物理研究所 一种控制人神经细胞重编程的信号通路及其应用

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023068826A1 (ko) * 2021-10-20 2023-04-27 서울시립대학교 산학협력단 자가조립된 rna 구조체를 포함하는 직접교차분화 유도용 조성물

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GB202017810D0 (en) 2020-12-23
EP3773749A1 (en) 2021-02-17
US20240218362A1 (en) 2024-07-04
JP2021520200A (ja) 2021-08-19
US11702656B2 (en) 2023-07-18
US20200377891A1 (en) 2020-12-03
WO2019200129A1 (en) 2019-10-17
AU2019252534A1 (en) 2020-10-29
GB202017804D0 (en) 2020-12-23
CN112312928A (zh) 2021-02-02
CA3096691A1 (en) 2019-10-17
GB2588307B (en) 2023-08-16
EP3773749A4 (en) 2021-12-22
GB2588307A (en) 2021-04-21

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