KR20200129708A - Suture thread and needle, and kit comprising the same - Google Patents

Abstract

A plurality of inelastic yarns arranged side by side to form a band, and the plurality of bands are braided to each other to form a symmetrical surface structure surrounding the elastic core yarn; As a cylinder-shaped body, a hollow portion is formed inside the body, and a surgical needle including a suture carrier installed in the hollow portion of the inner opening; And a kit comprising them is disclosed. The suture can achieve a stable fixation and a stable traction to the needle, and the surgical needle can stably fix the suture and also stably pull.

Description

Suture thread and needle, and kit comprising the same {Suture thread and needle, and kit comprising the same}

The present invention relates to a suture and a needle that can be used for suturing, ligation, fixation, lifting procedures, drug delivery, etc. of skin and soft tissue at a surgical site, and a kit including the same.

Sutures are used to suture and bond tissues to each other while tissues are healed after surgery and wound treatment, and suture strength and firmness are required. In general, the physical properties of sutures required are different depending on the surgical site and the characteristics of the wound, so in the past, natural sutures mainly made of natural materials such as silk or long yarn were used, but in recent years, various types of synthetic sutures have been developed due to the development of polymer technology. It has been developed and has been widely used in recent years as it has no tissue reactivity and infectivity concerns compared to existing natural sutures, and has excellent surgical properties. Among synthetic sutures, those having elasticity due to the nature of polymers are used not only in suturing the surgical site, but also in surgical methods for the purpose of removing wrinkles. In this method, after local anesthesia with the incision minimized, a lifting thread fixed in a hole (opening) formed on the side of a so-called atraumatic needle without needle eye is inserted into the inside of the skin using the needle. . Thereafter, by lifting the sagged skin in a desired direction using the lifting thread, the skin is tightened to remove wrinkles. Synthetic sutures with elasticity are used for such lifting procedures.

There are several types of sutures that can be used in these various procedures. These sutures can be divided into absorbable sutures that are naturally degraded and absorbed into the living body after a certain period of time, depending on their in vivo absorbability, and non-absorbable sutures that must be removed by reoperation because they remain undissolved even after the surgical tissue is joined. have.

As an example of the non-absorbable suture, a suture obtained by winding the surface of a silicone elastic thread with a non-tensile thread is disclosed. However, such a suture has a problem in that the non-tensile thread disposed on the surface of the silicone elastic body is not precisely symmetrically disposed by winding. Due to the non-symmetrical surface arrangement of the non-tensile thread, a problem of poor traction stability may easily occur when the suture fixed to the atraumatic needle is pulled and traction in the skin tissue during surgery. In addition, since the non-tensile thread wound on the surface of the suture does not have sufficient surface irregularities, it is easy to expose the problem that the state of fixation of the atraumatic needle in the hole is not sufficient. This problem makes the procedure uncomfortable during surgery.

In addition, during surgery, the suture is inserted into the hollow portion of the needle through an opening provided in the central side of the body of the atraumatic needle, and then fixed to the hollow portion for use. At this time, the operator pushes the needle and inserts the insertion part provided at the end of the needle into the skin, thereby injecting the suture into the skin. However, the operator presses or bends the central part of the needle to fix the thread, and the body part where the opening is installed does not have the support of the stainless steel that forms the body as much as the area of the opening. Problems may appear that may be bent, bent or even cut.

Accordingly, one object of the present invention is to provide a suture that can achieve stable fixation and stable traction for an injured needle.

Another object of the present invention is to provide a surgical needle capable of stably fixing a suture and also stably traction.

Another object of the present invention is to provide a surgical kit in which the suture and the surgical needle are integrated.

In order to achieve the object of the present invention described above, one aspect of the present invention

As a suture thread, the suture,

It includes an elastic core yarn extending in one direction and a coating layer surrounding the elastic core yarn,

The elastic core yarn includes an elastic yarn containing at least one elastic polymer,

The coating layer includes an inelastic yarn containing at least one non-elastic polymer, and a plurality of the non-elastic yarns are arranged side by side to form a band, and a plurality of the bands are braided to each other to provide a suture.

In one aspect of the present invention, the bands of even-numbered strands are braided to each other to form the coating layer, the even-numbered strands are 2 strands, 4 strands, 6 strands, 8 strands, 10 strands, 12 strands, It can be 14 or 16 strands.

In one aspect of the present invention, the elastic core yarn may include a plurality of strands, and the plurality of strands may be 2 to 10 strands.

In one aspect of the present invention, the coating layer may include a plurality of layers, and the plurality of layers may be one layer, two layers, three layers, four layers, or five layers.

In one aspect of the present invention, the width of the band may be in the range of 100 to 300 microns, and each of the inelastic yarns constituting the band may have a width in the range of 10 to 20 microns.

In one aspect of the present invention, the elastic core yarn is silicone rubber, natural rubber, isoprene rubber, butyl rubber, chloroprene rubber, styrene-butadiene rubber (SBR), acrylo-butadiene rubber (NBR), polybutadiene rubber, ethylene propylene It includes at least one monofilament yarn selected from the group consisting of rubber, ethylene propylene diene rubber, polyacrylate rubber, and a mixture of the above polymers, and the elastic core yarn may have a first elongation at break of 100% or more.

In one aspect of the present invention, the non-elastic yarn is made of polyester, polyamide, polyacrylonitrile, polyethylene, polypropylene, polyurethane, a copolymer of monomers used to polymerize the above polymers, and a mixture of the above polymers. A multifilament yarn of at least one non-absorbent material selected from the group consisting of may be included, and the inelastic yarn may have a second elongation at break of 20% or less, and the second elongation at break is greater than the first elongation at break. It is smaller than 50% so that the coating layer can suppress the elongation of the elastic core yarn.

In one aspect of the present invention, the coating layer may be colonized by biological tissue.

Another aspect of the present invention in order to achieve the other object of the present invention described above

As a surgical needle,

A cylinder-shaped body extending in one direction, the body having a hollow portion formed in the body;

An opening formed on one surface of the body to introduce the suture to the hollow part from the outside of the body;

A suture carrier installed in a portion of the hollow portion inside the opening, the carrier having a groove for gripping the suture; And

It provides a surgical needle comprising; an insertion portion formed at one end or both ends of the body to cut the skin and insert the suture carried through the hollow portion by the carrier into the skin.

In one aspect of the present invention, the carrier may have a shape of a cylinder having an outer diameter smaller than the inner diameter of the body.

In one aspect of the present invention, the suture may be a suture according to one aspect of the present invention.

In order to achieve another object of the present invention as described above, another aspect of the present invention is a surgical kit comprising a suture and a surgical needle,

The surgical needle,

A cylinder-shaped body extending in one direction, the body having a hollow portion formed in the body;

An opening formed on one surface of the body to introduce the suture to the hollow part from the outside of the body;

A suture carrier installed in a portion of the hollow portion inside the opening, the carrier having a groove for gripping the suture; And

Including; an insertion portion formed at one end or both ends of the body to cut the skin and insert the suture carried through the hollow portion by the carrier body into the skin,

The suture is a suture according to an aspect of the present invention described above,

The suture is inserted into the groove of the carrier to provide a surgical kit that is coupled to the surgical needle.

In the suture according to the present invention, the covering layer surrounding the elastic core yarn has a coating layer structure in which even number of bands formed by arranging inelastic yarns side by side are braided to each other. Therefore, since the coating layer has a very symmetrical surface arrangement, stability of traction can be improved when it is fixed to an atraumatic needle and then pulled and pulled in the skin tissue during surgery. In addition, since the suture has sufficient surface irregularities, it is also excellent in a fixed state at the opening of the injured needle. Therefore, the suture according to the present invention can conveniently perform procedures such as suturing, ligation, fixation, and lifting procedures of skin and soft tissue at the surgical site.

In the surgical needle of the present invention, the suture carrier installed in the hollow portion near the opening can reliably grip the suture and reinforce the needle body near the opening. Therefore, when the surgical needle of the present invention is used, the suture can be stably and reliably delivered to the insertion part, and problems in which the needle may be bent, bent, or cut during surgery can be effectively prevented.

1 is a schematic perspective view of a surgical suture according to embodiments of the present invention.
2 is a scanning electron microscope (SEM) photograph of a surface of a suture for a procedure according to various embodiments of the present invention, and a symmetric coating layer formed by braiding an even number of bands can be confirmed.
3 is a scanning electron microscope (SEM) photograph of a cross section of a suture for a procedure according to an embodiment of the present invention.
4 is a schematic perspective view showing the structure of a surgical needle according to an embodiment of the present invention.
5 is a schematic perspective view of a surgical kit including a surgical suture and a surgical needle according to an embodiment of the present invention.

Hereinafter, the present invention will be described in more detail with respect to a suture, a surgical needle, and a kit including the same according to various exemplary embodiments of the present invention. However, the description below is for illustrative purposes only. Therefore, it is clear to those with average knowledge in the technical field to which the present invention pertains that these can be variously modified and modified. In describing the present invention, detailed descriptions of related known functions or configurations are omitted so as not to obscure the subject matter of the present invention.

The suture according to the present invention has a suitable tensile property, suitable elasticity, flexibility, resistance to traction, and a non-slip surface so that it can be suitably used for suturing, ligation, fixation, lifting procedures, and drug delivery of the skin and soft tissue at the surgical site. Elastic core yarns and inelastic yarns are selected so that the suture has biocompatibility and does not cause an inflammatory reaction as much as possible. When the suture of the present invention is used for drug delivery, examples of drugs that can be delivered using the suture of the present invention are not particularly limited, but nonsteroidal anti-inflammatory drugs, antibiotics, various growth factors (FGF, VEGF, TGF-β, Ephrins, EGF). To this end, the suture according to the present invention includes an elastic core yarn and a coating layer comprising or made of inelastic yarn as a coating layer surrounding the elastic core yarn.

1 is a schematic perspective view of surgical sutures 10 and 10a according to embodiments of the present invention. Referring to FIG. 1 (a), the surgical suture 10 includes an elastic core yarn 1 extending in one direction and a coating layer 2 surrounding the elastic core yarn 1. Referring to FIG. 1(b), the surgical suture 10a includes an elastic core yarn 1a, 1b extending in one direction and a coating layer 2a surrounding the elastic core yarn 1a, 1b. In the suture of the present invention, the elastic core yarn may include a plurality of strands, and the number of the plurality of strands is not particularly limited, but may be 2 to 10 strands, for example, 2 strands, 3 strands, 4 strands, It can be 5 strands, 6 strands, 7 strands, 8 strands, 9 strands or 10 strands.

The suture 10a according to FIG. 1(b) differs from the suture 10 of FIG. 1(a) having only one elastic core yarn 1 in that it has two elastic core yarns 1a and 1b. . When there are a plurality of elastic core yarns as described above, even if any one of the elastic core yarns is broken, there is an advantage in that the other elastic core yarns can maintain the overall shape of the suture and mechanical properties such as tensile force to be maintained by the suture.

The diameters of the elastic core yarns 1 shown in Fig. 1(a) and the elastic core yarns 1a and 1b shown in Fig. 1(b) are each 0.1 to 3 mm, for example 0.3 to 2 mm, It may be 0.5 to 1.5 mm, 0.5 to 1.2 mm, 0.3 to 1 mm, or 0.5 to 0.8 mm.

The elastic core yarns 1, 1a, 1b include elastic yarns containing at least one elastic polymer. Alternatively, the elastic core yarns 1, 1a, 1b may be made of elastic yarns containing one or more elastic polymers. The elastic core yarn (1, 1a, 1b) includes at least one monofilament yarn selected from the group consisting of silicone rubber, natural rubber, isoprene rubber, butyl rubber, and mixtures of the aforementioned polymers. These elastic core yarns may have a first elongation at break of 100% or more, for example 200% or more, 300% or more, 400% or more, or 500% or more. This high elongation at break is a necessary characteristic to help with sufficient muscle contraction and relaxation exercises, and stable resistance to fatigue from repeated strength exercises.

The covering layers 2 and 2a include nonelastic yarns containing at least one nonelastic polymer. Alternatively, the covering layers 2 and 2a may be made of inelastic yarns containing one or more inelastic polymers. The covering layers 2 and 2a have a feature in which bands formed by arranging a plurality of inelastic yarns side by side are braided to each other. Even-numbered strands may be braided to each other to form a symmetrical braiding material (array) to form a covering layer (2, 2a), and the even-numbered strands are, for example, 4 strands, 6 strands, 8 strands, 10 It can be 12 strands, 14 strands or 16 strands.

The width of the band may be in the range of 100 to 300 microns, for example, in the range of 150 to 250 microns, or in the range of 180 to 240 microns. Each of the inelastic yarns constituting the band may have a width in the range of 10 to 20 microns. To this end, each of the inelastic yarns may have a thickness of 50 to 200 denier (d), for example, 70 to 180 denier (d) or 70 to 150 denier (d). The inelastic yarn is at least one selected from the group consisting of polyester, polyamide, polyacrylonitrile, polyethylene, polypropylene, polyurethane, a copolymer of monomers used to polymerize the above polymers, and a mixture of the above polymers It may include a multifilament yarn of a non-absorbent material. If desired, a material of inelastic yarn may be selected so that the covering layers 2 and 2a can be colonized by biological tissues.

The inelastic yarn may have a second elongation at break of 20% or less, for example 18% or less, or 15% or less. The second elongation at break of the inelastic yarn is 50% or more, for example, 60% or more, 70% or more, 80% or more, 90% or more, or 100% or more than the first breaking elongation of the elastic core yarn (1, 1a, 1b). It is smaller so that the covering layers 2, 2a can effectively suppress the elongation of the elastic core yarns 1, 1a, 1b.

2 is a scanning electron microscope (SEM) of the surface of sutures 10 and 10a for procedures according to various embodiments of the present invention. Referring to this, various types of symmetric coating layers formed on the surfaces of the surgical sutures 10 and 10a can be identified. The coating layer shown in Fig. 2(a) represents one layer of coating layers 2 and 2a formed by braiding four strands symmetrically. The coating layer shown in Fig. 2(b) represents one layer of coating layers 2 and 2a in which 6 strands of bands are symmetrically braided. The coating layer shown in Fig. 2(c) represents a single layer of coating layers 2 and 2a formed by braiding 8 strands symmetrically. The coating layer shown in Fig. 2(d) is a two-layered coating layer (2,2a), each of which is a layer formed by braiding four strands symmetrically. Therefore, the suture thread 10 of Fig. 2(d) The covering layers 2 and 2a of 10a) are formed by braiding 8 strands symmetrically. The bands are nonelastic yarns made of polyethylene terephthalate (PET). As described above, in the surgical sutures 10 and 10a according to various embodiments of the present invention, the covering layers 2 and 2a may include a plurality of layers, the plurality of layers being, for example, one layer. , It may be a two-layer, three-layer or four-layer.

The covering layer (2, 2a) can protect the suture (10, 10a) from being cut by the sharp edge of the surgical equipment, and when the elastic core yarn (1, 1a, 1b) has a slippery surface like a silicone elastic yarn By covering the slippery surface and providing an appropriate friction force, it is possible to help to be well pulled by a needle or the like, and if necessary, a fabric piece can be easily manufactured using this suture.

3 is a scanning electron microscope (SEM) photograph of a cross section of a surgical suture 10a having two-stranded elastic core yarns 1a and 1b according to an embodiment of the present invention. Referring to FIG. 3, the suture 10a can see two-stranded silicone elastic core yarns 1a and 1b extending in the longitudinal direction, and a covering layer 2a surrounding the silicone elastic core yarns 1a and 1b. .

The total diameter of the surgical suture 10a according to the present invention may be 0.3 to 5 mm, for example 0.5 to 3 mm, 0.8 to 2 mm, 1 to 1.7 mm, 1 to 1.5 mm, or 1 to 0.9 mm. The total diameter of the surgical suture (10a) can be controlled using the number and thickness of the covering layers (2, 2a), the thickness and the number of strands of the elastic core yarns (1, 1a, 1b), and the like, through which the suture (10a) ) Thickness, tensile strength, and other mechanical properties can be controlled.

In the surgical suture (10a) according to the present invention, the inelastic yarn constituting the elastic core yarn (1, 1a, 1b) and the covering layer (2, 2a) is preferably one having biocompatibility. In the present specification, biocompatibility means not causing an inflammatory reaction to the skin in contact with the human skin for a certain period of time, for example, for 1 year, 6 months, or 1 month.

The surgical suture (10a) according to the present invention is preferably stretchable to 100% or less of the original length, for example, 80% or less or 70% or less or more, and immediately elastic to the original length when external force is removed. You can recover.

Next, a needle for a procedure and a kit including the same according to embodiments of the present invention will be described in more detail.

4 is a schematic perspective view showing the structure of a surgical needle 100 according to an embodiment of the present invention.

Referring to FIG. 4, the surgical needle 100 is an atraumatic needle without a needle eye. The surgical needle 100 has a cylindrical body 20 extending in the longitudinal direction. A hollow part 11 is formed inside the cylindrical body. A suture for surgery may be inserted into the hollow part 11. An opening 30 is formed on one surface of the body 20 for introducing sutures into the hollow portion 11 from the outside of the body 20. A suture carrier 50 is installed in the portion of the hollow portion 11 inside the opening 30. The suture carrier 50 includes a groove 32 for reliably gripping the suture. The suture carrier 50 is not particularly limited in shape as long as it can be inserted into the hollow portion 11 inside the body 20, but can be smoothly transported across the hollow portion 11 to the insertion portion 21 So that it may have a shape of a cylinder having an outer diameter smaller than the inner diameter of the body 20. The suture inserted into the groove 32 and conveyed to the insertion part 21 by the suture carrier 50 is not particularly limited, and, for example, a suture for a procedure according to specific embodiments of the present invention shown in FIG. 10, 10a). The material of the body 20 may be metal, for example, stainless steel. The material of the suture carrier 50 is not particularly limited, and may be plastic or metal, and may be, for example, stainless steel, polyethylene, polypropylene, or polyester.

The surgical needle 100 also has insertion portions 21 formed at both ends of the body 20. In this embodiment, although the insertion portions 21 are formed at both ends of the body 20, the insertion portion 21 may be formed only at one end of the body 20. The insertion part 21 cuts the skin of the person to be treated and inserts the suture carried by the suture carrier 50 into the skin. The insertion part 21 may be in the shape of a blade inclined with an appropriate inclination.

Referring again to FIG. 4, the surgical needle 100 includes cutting grooves 40 at regular intervals along the length direction of the body 20. The cutting groove 40 may be made of a V-shaped blade. The cutting groove 400 is convenient when inserting the suture into the body 20, and the length can be adjusted by cutting the suture. Since the skin lifting procedure is a procedure in which a suture is inserted into the skin to pull the sagged skin, the length of the suture is important according to the contour and area of the face. Therefore, the presence of the cutting groove 40 can shorten the skin lifting procedure time.

5 is a schematic perspective view of a surgical kit 200 including a surgical suture 10 and a surgical needle 100 according to an embodiment of the present invention.

Referring to FIG. 5, the surgical kit 200 includes a surgical suture 10 and a surgical needle 100. Since the surgical needle 100 shown in FIG. 5 is the same as the surgical needle 100 shown in FIG. 4, the description of the surgical needle 100 shown in FIG. 100) applies as it is. In this drawing, the surgical suture 10 is shown as a surgical suture 10 according to an embodiment of the present invention shown in FIG. 1(a), but is not limited thereto, and the surgical suture 10 For example, it may be replaced with a suture 10a for a procedure according to another embodiment of the present invention shown in FIG. 1(b). In the surgical kit 200, the surgical suture 10 is inserted into the groove 32 installed in the suture carrier 50 and securely gripped. Accordingly, when the suture carrier 50 moves to the insertion portion 21 of either end of both ends, the suture 10 is also drawn by the carrier 50 and is transported to the insertion portion 21. When the surgeon inserts the blade-shaped insertion portion 21 into the skin by cutting the skin of the surgeon, the suture 10 carried by the insertion portion 21 may be pushed into the skin accordingly.

Stability of suture traction may be improved by using a suture having a surface structure by symmetric braiding according to the present invention having the structure described above, a surgical needle including a suture carrier installed in the hollow part, or a kit including them. In addition, it is possible to stably and reliably transfer the suture to the insertion part, and it is possible to efficiently prevent the problem that the needle may be bent, bent, or cut during surgery.

Hereinafter, the present invention will be described in more detail using the following examples, but the present invention is not limited to the following examples.

Example One

Polydimethylsiloxane (PDMS) polymer (manufacturer: Avantor, product number: MED-4750 High Consistency Elastomers) was extruded to prepare two types of elastic yarn filaments having a circular cross section of about 200 microns in diameter and about 340 microns in diameter.

A band of about 230 microns in width was formed by placing 20 strands of PET multifilament yarns having a fineness of 70 denier side by side. After arranging the two types of elastic yarn filaments side by side, the two bands are braided on the surfaces of the two types of elastic yarn filament cores, and a surface layer of about 700 microns in thickness consisting of symmetric braiding around the core Formed.

Table 1 shows various physical properties of this suture.

Example 2

Polydimethylsiloxane polymer (manufacturer: Avantor, product number: MED-4750 High Consistency Elastomers) was extruded to produce two types of elastic yarn filaments having a circular cross section of about 400 microns in diameter and about 340 microns in diameter.

A band of about 230 microns in width was formed by arranging 20 strands of PET multifilament yarn with a fineness of 70 denier side by side. After arranging the two types of elastic yarn filaments side by side, the six strands of the band are braided on the surface of the two types of elastic yarn filament cores, and a surface layer of about 900 microns in thickness consisting of symmetric braiding around the core Formed.

2(b) shows the symmetrical braiding surface layer of the surgical suture obtained in this way, and FIG. 3 shows a cross-section of the surgical suture. Table 1 shows various physical properties of this suture.

Example 3

Polydimethylsiloxane polymer (manufacturer: Avantor, product number: MED-4750 High Consistency Elastomers) was extruded to produce two types of elastic yarn filaments having a circular cross section of about 400 microns in diameter and about 340 microns in diameter.

A band of about 230 microns in width was formed by arranging 20 strands of PET multifilament yarn with a fineness of 70 denier side by side. After arranging the two types of elastic yarn filaments side by side, the 8 strands of the band are braided on the surfaces of the two types of elastic yarn filament cores, and a surface layer of about 950 microns in thickness consisting of symmetric braiding around the core Formed.

2(c) shows the symmetrical braiding surface layer of the surgical suture obtained in this way. Table 1 shows various physical properties of this suture.

Example 4

Polydimethylsiloxane polymer (manufacturer: Avantor, product number: MED-4750 High Consistency Elastomers) was extruded to produce two types of elastic yarn filaments having a circular cross section of about 520 microns in diameter and about 340 microns in diameter.

A band of about 230 microns in width was formed by arranging 20 strands of PET multifilament yarn with a fineness of 70 denier side by side. After arranging the two types of elastic yarn filaments side by side, the 16 strands of the band are braided on the surfaces of the two types of elastic yarn filament cores, and a surface layer of about 1,000 microns in thickness consisting of symmetric braiding around the core Formed.

Table 1 shows various physical properties of this suture.

Example 5

A suture was formed in the same manner as in Example 1, except that the surface layer having a thickness of about 800 microns was formed as two layers. Table 1 shows various physical properties of this suture.

Example 6

A suture was formed in the same manner as in Example 2, except that the surface layer having a thickness of about 950 microns was formed as two layers. Table 1 shows various physical properties of this suture.

Example 7

A suture was formed in the same manner as in Example 3, except that a surface layer having a thickness of about 1,000 microns was formed as two layers. Table 1 shows various physical properties of this suture.

Example 8

A suture was formed in the same manner as in Example 4, except that a surface layer having a thickness of about 1,100 microns was formed as two layers. Table 1 shows various physical properties of this suture.

Example 9

A suture was formed in the same manner as in Example 1, except that polyisoprene (PIP) rubber (manufacturer: KRATON, product number: Cariflex IR0310 KU) was used instead of polydimethylsiloxane polymer as the material of the two types of elastic yarn filaments. Table 1 shows various physical properties of this suture.

Example 10

A suture was formed in the same manner as in Example 2, except that polyisoprene rubber (manufacturer: KRATON, product number: Cariflex IR0310 KU) was used instead of polydimethylsiloxane polymer as the material of the two elastic yarn filaments. Table 1 shows various physical properties of this suture.

Example 11

A suture was formed in the same manner as in Example 4, except that polyisoprene rubber (manufacturer: KRATON, product number: Cariflex IR0310 KU) was used instead of polydimethylsiloxane polymer as the material of the two elastic yarn filaments. Table 1 shows various physical properties of this suture.

Example 12

As a material for forming the surface layer, a suture was formed in the same manner as in Example 1, except that a band obtained by using a nylon 6 multifilament yarn having a fineness of 150 denier instead of a PET multifilament yarn was used. Table 1 shows various physical properties of this suture.

Example 13

A suture was formed in the same manner as in Example 2, except that a band obtained by using nylon 6 multifilament yarn of 150 denier fineness instead of PET multifilament yarn as a material for forming the surface layer was used. Table 1 shows various physical properties of this suture.

Example 14

A suture was formed in the same manner as in Example 4, except that a band obtained by using nylon 6 multifilament yarn of 150 denier fineness instead of PET multifilament yarn as a material for forming the surface layer was used. Table 1 shows various physical properties of this suture.

Example 15

Polydimethylsiloxane polymer (manufacturer: Avantor, product number: MED-4750 High Consistency Elastomers) was extruded to prepare three types of elastic yarn filaments having a circular cross section of about 200 microns in diameter, about 340 microns in diameter, and about 400 microns in diameter.

A band of about 230 microns in width was formed by placing 20 strands of PET multifilament yarns having a fineness of 70 denier side by side. After arranging the two types of elastic yarn filaments side by side, the four bands are braided on the surface of the three types of elastic yarn filament cores, and a surface layer of about 950 microns in thickness consisting of symmetric braiding around the core Formed.

Table 1 shows various physical properties of this suture.

Example 16

Polydimethylsiloxane polymer (manufacturer: Avantor, product number: MED-4750 High Consistency Elastomers) was extruded to prepare three types of elastic yarn filaments having a circular cross section of about 400 microns in diameter, about 340 microns in diameter, and about 520 microns in diameter.

A band of about 230 microns in width was formed by arranging 20 strands of PET multifilament yarn with a fineness of 70 denier side by side. After arranging the two types of elastic yarn filaments side by side, the 8 strands of the band are braided on the surface of the three types of elastic yarn filament cores, and a surface layer of about 1,100 microns in thickness consisting of symmetric braiding around the core Formed.

Table 1 shows various physical properties of this suture.

Example 17

Polydimethylsiloxane polymer (manufacturer: Avantor, product number: MED-4750 High Consistency Elastomers) was extruded to prepare three types of elastic yarn filaments having a circular cross section of about 400 microns in diameter, about 340 microns in diameter, and about 520 microns in diameter.

A band of about 230 microns in width was formed by arranging 20 strands of PET multifilament yarn with a fineness of 70 denier side by side. After arranging the two types of elastic yarn filaments side by side, the 10 strands of the band are braided on the surface of the three types of elastic yarn filament cores, and a surface layer of about 1,300 microns in thickness consisting of symmetric braiding around the core Formed.

Table 1 shows various physical properties of this suture.

Example 18

Polydimethylsiloxane polymer (manufacturer: Avantor, product number: MED-4750 High Consistency Elastomers) was extruded to produce three types of elastic yarn filaments having a circular cross section of about 520 microns in diameter, about 340 microns in diameter, and about 600 microns in diameter. .

A band of about 230 microns in width was formed by arranging 20 strands of PET multifilament yarn with a fineness of 70 denier side by side. After arranging the two types of elastic yarn filaments side by side, the 16 strands of the band are braided on the surface of the three types of elastic yarn filament cores, and a surface layer of about 1,500 microns in thickness consisting of symmetric braiding around the core Formed.

Table 1 shows various physical properties of this suture.

Comparative example One

Tensile strength was measured under the same conditions for a commercially available conventional surgical suture (manufacturer: KORPO, product number: E3.5J1.5R165). Table 1 shows various physical properties of the suture of this comparative example.

Tensile test method

For the sutures prepared in Examples and Comparative Examples, the maximum load (N) and tensile strain were measured under a speed condition of 10 mm/min using a general UTM universal tester (manufacturer: Instron, model name: Instron 3343). The load at break was defined as the maximum load (N). The tensile test results of each Example and Comparative Example in Table 1 are average values of the results of five tests for each sample.

Biocompatibility test ( Biotoxicity test )

Death and cell growth of L-929 cells by applying the dilution extraction method or the direct/indirect contact method to the suture test sample according to the Tests for in vitro cytotoxicity criteria. , The degree of inhibition such as proliferation was measured to confirm biocompatibility.

Shout
Core yarn
Kinds Shout
Core yarn
Number In the surface layer
Multifilament
Type of yarn Surface layer
Forming
Number of bands Surface layer
Number of floors Load (N) Seal
Strain
(%) Biotoxicity test
result Example 1 PDMS rubber 2 PET 2 One 15.3 907 No toxicity Example 2 PDMS rubber 2 PET 6 One 19.2 779 No toxicity Example 3 PDMS rubber 2 PET 8 One 25.3 635 No toxicity Example 4 PDMS rubber 2 PET 16 One 36.8 474 No toxicity Example 5 PDMS rubber 2 PET 2 2 17.4 834 No toxicity Example 6 PDMS rubber 2 PET 6 2 24.0 656 No toxicity Example 7 PDMS rubber 2 PET 8 2 37.1 533 No toxicity Example 8 PDMS rubber 2 PET 16 2 50.3 401 No toxicity Example 9 PIP rubber 2 PET 2 One 13.6 815 No toxicity Example 10 PIP rubber 2 PET 6 One 18.1 695 No toxicity Example 11 PIP rubber 2 PET 16 One 28.7 395 No toxicity Example 12 PDMS rubber 2 Nylon 6 2 One 14.7 879 No toxicity Example 13 PDMS rubber 2 Nylon 6 6 One 17.5 751 No toxicity Example 14 PDMS rubber 2 Nylon 6 16 One 30.4 465 No toxicity Example 15 PDMS rubber 3 PET 4 One 18.28 936 No toxicity Example 16 PDMS rubber 3 PET 8 One 23.96 653 No toxicity Example 17 PDMS rubber 3 PET 10 One 36.51 611 No toxicity Example 18 PDMS rubber 3 PET 16 One 51.12 592 No toxicity Comparative Example 1 PDMS rubber - PET - - 24.37 627 No toxicity

Referring to Table 1, the suture of the present invention has significantly increased at least one of the maximum load and tensile strain compared to the conventional suture, and specifically, the maximum load (N) and tensile strain are about 10% or more under several conditions. And a significant increase of more than 30%, and it was confirmed that there was no biotoxicity.

In the above, although the present invention has been described by the limited embodiments and drawings, the present invention is not limited thereto, and various modifications and modifications within the scope of the present invention by those of ordinary skill in the art to which the present invention pertains. Needless to say, it can be transformed.

1, 1a, 1b: elastic core yarn
10, 10a: surgical suture
100: surgical needle
20: body
11: hollow part
21: insertion part (blade)
30: opening
40: cutting groove
50: suture carrier

Claims (14)

As a suture thread, the suture,
It includes an elastic core yarn extending in one direction and a coating layer surrounding the elastic core yarn,
The elastic core yarn includes an elastic yarn containing at least one elastic polymer,
The coating layer includes a non-elastic yarn containing at least one non-elastic polymer, a plurality of the non-elastic yarns are arranged side by side to form a band, and a plurality of the bands are braided to each other. The suture according to claim 1, wherein the bands are braided with even-numbered bands to form the covering layer. The suture according to claim 2, wherein the even-numbered strand is 2 strands, 4 strands, 6 strands, 8 strands, 10 strands, 12 strands, 14 strands or 16 strands. The suture according to claim 1, wherein the elastic core yarn comprises a plurality of strands. The suture according to claim 4, wherein the plurality of strands are selected from the range of 2 to 10 strands. The suture according to claim 1, wherein the covering layer comprises a plurality of layers. The suture according to claim 6, wherein the plurality of layers are one layer, two layers, three layers, four layers, or five layers. The suture according to claim 1, wherein the width of the band is in the range of 100 to 300 microns, and each of the inelastic yarns constituting the band has a width in the range of 10 to 20 microns. The method of claim 1, wherein the elastic core yarn is silicone rubber, natural rubber, isoprene rubber, butyl rubber, chloroprene rubber, styrene-butadiene rubber (SBR), acrylo-butadiene rubber (NBR), polybutadiene rubber, ethylene propylene rubber, Ethylene propylene diene rubber, polyacrylate rubber, and at least one monofilament yarn selected from the group consisting of a mixture of the above polymers,
The elastic core yarn suture, characterized in that having a first breaking elongation of 100% or more. The group consisting of polyester, polyamide, polyacrylonitrile, polyethylene, polypropylene, polyurethane, a copolymer of monomers used to polymerize the above polymers, and a mixture of the above polymers. It includes at least one non-absorbent material multifilament yarn selected from,
The inelastic yarn has a second elongation at break of 20% or less,
The second elongation at break is 50% or more smaller than the first elongation at break, so that the covering layer can suppress the elongation of the elastic core yarn. As a surgical needle,
A cylinder-shaped body extending in one direction, the body having a hollow portion formed in the body;
An opening formed on one surface of the body to introduce the suture to the hollow portion from the outside of the body;
A suture carrier installed in a portion of the hollow portion inside the opening, the carrier having a groove for gripping the suture; And
An insertion portion formed at one end or both ends of the body to cut the skin and insert the suture carried through the hollow portion by the carrier into the skin. The surgical needle according to claim 11, wherein the carrier has a shape of a cylinder having an outer diameter smaller than the inner diameter of the body. The surgical needle according to claim 11, wherein the suture is a suture according to any one of claims 1 to 10. As a surgical kit comprising a suture and a surgical needle,
The surgical needle,
A cylinder-shaped body extending in one direction, the body having a hollow portion formed in the body;
An opening formed on one surface of the body to introduce the suture to the hollow portion from the outside of the body;
A suture carrier installed in a portion of the hollow portion inside the opening, the carrier having a groove for gripping the suture; And
Includes; an insertion part formed at one end or both ends of the body to cut the skin and insert the suture conveyed through the hollow part by the carrier into the skin,
The suture is a suture according to any one of claims 1 to 10,
The suture is inserted into the groove of the carrier and is coupled to the surgical needle.

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