KR102274565B1 - Suture thread and kit comprising the same - Google Patents

Abstract

a suture having a composite yarn structure in which a plurality of inelastic yarns are arranged side by side to form a band, and the plurality of bands are braided to each other to form a symmetrical surface tissue surrounding the elastic core yarn; A cylindrical body, the hollow part is formed in the inside of the body, the surgical needle comprising a suture carrier installed in the hollow part inside the opening; and kits comprising them are disclosed. The suture can achieve stable fixation and stable traction with respect to the needle, and the surgical needle can stably fix the suture and also stably traction.

Description

Suture and kit comprising the same

The present invention relates to a suture that can be used for suture, ligation, fixation, lifting procedure, drug delivery, and the like of skin and soft tissue at a surgical site, and a kit including the same.

Sutures are used to suture and bond tissues together while the tissues are healing after surgery and wound healing, and properties of suture strength and firmness are required. In general, since the physical properties of the suture required are different depending on the surgical site and the characteristics of the wound, natural sutures made of natural materials such as silk or long yarn were mainly used in the past, but in recent years, various types of synthetic sutures have been used due to the development of polymer technology. Compared to the existing natural sutures, there is no risk of tissue reactivity and infectivity, and it is widely used in recent years because of its excellent operation performance. Among synthetic sutures, those having elasticity due to the nature of the polymer are used not only to suture the surgical site, but also to surgical procedures performed for the purpose of removing wrinkles. In this method, after local anesthesia of the treated area with minimal incision, a lifting thread fixed in the hole (opening) formed on the side of the so-called atraumatic needle without the needle eye is inserted into the skin using the needle. . Then, by lifting the sagging skin in a desired direction using the lifting thread, the wrinkles are removed by tightening the skin. A synthetic suture with elasticity is used for this lifting procedure.

There are several types of sutures that can be used for these various procedures. These sutures can be divided into absorbable sutures, which are naturally decomposed and absorbed into the body after a certain period of time after the procedure, and non-absorbable sutures, which remain undecomposed even after the operated tissue is joined, and must be removed by reoperation, depending on bioabsorbability. have.

As an example of the non-absorbable suture, a suture obtained by winding the surface of a silicone elastomer thread with a non-tensile thread is disclosed. However, these sutures have a problem in that the non-tensile thread arranged on the surface of the silicone elastomer thread is not precisely and symmetrically arranged by winding. Due to the non-symmetrical surface arrangement of the non-tensile thread, when the suture fixed to the atraumatic needle is pulled and pulled within the skin tissue during surgery, the problem of poor traction stability may easily occur. In addition, since the non-tensile thread wound on the surface of the suture described above does not have sufficient surface unevenness, the problem that the fixation state of the atraumatic needle to the hole is likewise not sufficient is also likely to be exposed. These problems make the operation inconvenient during surgery.

In addition, during surgery, the suture is inserted into the hollow part inside the needle through an opening provided in the central side of the body of the atraumatic needle, and then fixed to the hollow part and used. At this time, the operator presses the needle and inserts the insertion part provided at the end of the needle into the skin, thereby inserting the suture into the skin. However, the operator presses or bends the central part of the needle in order to fix the thread, but the body part where the opening is installed does not have the bearing force of the stainless steel constituting the body as much as the area of the opening. Problems can arise that can bend, bend, or even cut.

Accordingly, one object of the present invention is to provide a suture capable of achieving stable fixation and stable traction for an atraumatic needle.

Another object of the present invention is to provide a needle for a procedure that can stably fix the suture and can be pulled stably.

Another object of the present invention is to provide a kit for surgery in which the suture and the needle for the procedure are integrated.

In order to achieve the above object of the present invention, one aspect of the present invention is

A suture thread, the suture comprising:

Comprising an elastic core yarn extending in one direction and a coating layer surrounding the elastic core yarn,

The elastic core yarn includes an elastic yarn comprising at least one elastic polymer,

The covering layer includes a non-elastic yarn including at least one non-elastic polymer, a plurality of the non-elastic yarns are arranged side by side to form a band, and a plurality of the bands are braided to each other.

In one aspect of the present invention, as for the bands, even-numbered bands are braided to each other to form the coating layer, and the even-numbered strands are 2 strands, 4 strands, 6 strands, 8 strands, 10 strands, 12 strands, It may be 14 strands or 16 strands.

In one aspect of the present invention, the elastic core yarn may include a plurality of strands, and the plurality of strands may be 2 to 10 strands.

In one aspect of the present invention, the coating layer may include a plurality of layers, and the plurality of layers may be one layer, two layers, three layers, four layers, or five layers.

In one aspect of the present invention, the width of the band may be in the range of 100 to 300 microns, and each of the inelastic yarns constituting the band may have a width in the range of 10 to 20 microns.

In one aspect of the present invention, the elastic core yarn is silicone rubber, natural rubber, isoprene rubber, butyl rubber, chloroprene rubber, styrene-butadiene rubber (SBR), acrylo-butadiene rubber (NBR), polybutadiene rubber, ethylene propylene It includes at least one monofilament yarn selected from the group consisting of rubber, ethylene propylene diene rubber, polyacrylate rubber, and a mixture of the above-mentioned polymers, and the elastic core yarn may have a first elongation at break of 100% or more.

In one aspect of the present invention, the inelastic yarn is made of polyester, polyamide, polyacrylonitrile, polyethylene, polypropylene, polyurethane, a copolymer of monomers used to polymerize the above-mentioned polymers, and a mixture of the above-mentioned polymers. It may include a multifilament yarn of at least one non-absorbent material selected from the group consisting of, the inelastic yarn may have a second elongation at break of 20% or less, and the second elongation at break is greater than the first elongation at break. It is 50% or more smaller, so that the coating layer can suppress the elongation of the elastic core yarn.

In one aspect of the present invention, the coating layer may be colonized by biological tissue.

In order to achieve the other object of the present invention, another aspect of the present invention is

As a surgical needle,

A cylindrical body extending in one direction, the body having a hollow portion formed inside the body;

an opening formed on one surface of the body to introduce the suture into the hollow portion from the outside of the body;

A suture carrier installed in a portion of the hollow part inside the opening, the carrier having a groove for holding the suture; and

It provides a surgical needle comprising a; an insertion unit formed at one or both ends of the body to cut the skin and insert the suture delivered through the hollow portion by the carrier into the skin.

In one aspect of the present invention, the carrier member may have the shape of a cylinder having an outer diameter smaller than the inner diameter of the body.

In one aspect of the present invention, the suture may be the suture according to the one aspect of the present invention.

In order to achieve another object of the present invention, another aspect of the present invention is a kit for surgery including a suture and a needle for surgery,

The surgical needle is

A cylindrical body extending in one direction, the body having a hollow portion formed inside the body;

an opening formed on one surface of the body to introduce the suture into the hollow portion from the outside of the body;

A suture carrier installed in a portion of the hollow part inside the opening, the carrier having a groove for holding the suture; and

It includes; an insertion part formed at one or both ends of the body to cut the skin and insert the suture delivered through the hollow part by the carrier into the skin; and

The suture is a suture according to an aspect of the present invention,

The suture provides a kit for surgery that is coupled to the needle for the procedure by being inserted into the groove of the carrier.

In the suture according to the present invention, the covering layer surrounding the elastic core yarn has a covering layer structure in which an even number of bands formed by arranging inelastic yarns side by side are braided to each other. Therefore, since the coating layer has a very symmetrical surface arrangement, the stability of traction can be improved when it is pulled and pulled within the skin tissue during surgery after fixing it to an atraumatic needle. In addition, since the above-mentioned suture has sufficient surface unevenness, the fixation state in the opening of the atraumatic needle is also excellent. Therefore, the suture according to the present invention can conveniently perform procedures such as suture, ligation, fixation, and lifting of the skin and soft tissue of the surgical site.

In the surgical needle of the present invention, the suture carrier installed in the hollow portion near the opening can securely grip the suture and reinforce the needle body near the opening. Therefore, by using the surgical needle of the present invention, the suture can be stably and reliably delivered to the insertion part, and the problem that the needle may be bent, bent, or cut during surgery can be effectively prevented.

1 is a schematic perspective view of a suture for a procedure according to embodiments of the present invention.
2 is a scanning electron microscope (SEM) photograph of the surface of a suture for a procedure according to various embodiments of the present invention, and it can be seen that an even number of bands are braided to form a symmetrical coating layer.
3 is a scanning electron microscope (SEM) photograph of a cross-section of a suture for surgery according to an embodiment of the present invention.
4 is a schematic perspective view showing the structure of a needle for a procedure according to an embodiment of the present invention.
5 is a schematic perspective view of a kit for a procedure including a suture for a procedure and a needle for a procedure according to an embodiment of the present invention.

Hereinafter, the present invention will be described in more detail with respect to a suture, a surgical needle, and a kit including the same according to various exemplary embodiments of the present invention. However, the description below is for illustrative purposes only. Therefore, it is apparent to those of ordinary skill in the art to which the present invention pertains that they can be variously modified and modified. In describing the present invention, detailed descriptions of related known functions or configurations are omitted so as not to obscure the gist of the present invention.

The suture according to the present invention has suitable tensile properties, suitable elasticity, flexibility, resistance to traction, and a non-slip surface so that it can be used for suture, ligation, fixation, lifting procedure, drug delivery, etc. of the skin and soft tissue of the surgical site. An elastic core yarn and a non-elastic yarn are selected so that the suture is biocompatible and does not cause an inflammatory reaction as much as possible. When the suture of the present invention is used for drug delivery, examples of drugs that can be delivered using the suture of the present invention are not particularly limited, but nonsteroidal anti-inflammatory drugs, antibiotics, various growth factors (FGF, VEGF, TGF-β, Ephrins, EGF). To this end, the suture according to the present invention includes an elastic core yarn and a coating layer comprising a non-elastic yarn or made of a non-elastic yarn as a covering layer surrounding the elastic core yarn.

1 is a schematic perspective view of sutures 10 and 10a for a procedure according to embodiments of the present invention. Referring to Figure 1 (a), the surgical suture 10 includes an elastic core yarn (1) extending in one direction and a coating layer (2) surrounding the elastic core yarn (1). Referring to FIG. 1B , the suture 10a for surgery includes elastic core yarns 1a and 1b extending in one direction and a coating layer 2a surrounding the elastic core yarns 1a and 1b. In the suture of the present invention, the elastic core yarn may include a plurality of strands, and the number of the plurality of strands is not particularly limited, but may be 2 to 10 strands, for example, 2 strands, 3 strands, 4 strands, 5 strands, 6 strands, 7 strands, 8 strands, 9 strands, or 10 strands.

The suture 10a according to Fig. 1(b) is different from the suture 10 of Fig. 1(a) having only one elastic core yarn 1 in that it has two elastic core yarns 1a and 1b. . When there are a plurality of elastic core yarns as described above, there is an advantage that the other elastic core yarns can maintain the overall shape of the suture and mechanical properties such as tensile force to be maintained by the suture even if one elastic core yarn is broken.

The diameter of the elastic core yarn (1) shown in Figure 1 (a) and the diameter of the elastic core yarn (1a, 1b) shown in Figure 1 (b) are respectively 0.1 to 3 mm, for example 0.3 to 2 mm, 0.5 to 1.5 mm, 0.5 to 1.2 mm, 0.3 to 1 mm or 0.5 to 0.8 mm.

The elastic core yarns 1, 1a, 1b include elastic yarns comprising at least one elastic polymer. Alternatively, the elastic core yarns 1, 1a, 1b may be made of elastic yarns comprising one or more elastic polymers. The elastic core yarns 1, 1a, and 1b include at least one monofilament yarn selected from the group consisting of silicone rubber, natural rubber, isoprene rubber, butyl rubber, and mixtures of the aforementioned polymers. These elastic core yarns may have a first elongation at break of 100% or more, such as 200% or more, 300% or more, 400% or more, or 500% or more. Such a high elongation at break is a necessary property to help with sufficient muscle contraction and relaxation exercises, and stable resistance to fatigue from repeated strength training.

The coating layers 2 and 2a include non-elastic yarns containing at least one non-elastic polymer. Alternatively, the covering layers 2 and 2a may be made of a non-elastic yarn including at least one non-elastic polymer. The covering layers 2 and 2a have a characteristic in which bands formed by arranging a plurality of inelastic yarns side by side are braided to each other. Bands of even-numbered strands may be braided to each other to form a symmetrical braided product (piece) to form the covering layer 2, 2a, wherein the even-numbered strands are, for example, 4 strands, 6 strands, 8 strands, 10 strands. strand, 12 strand, 14 strand or 16 strand.

The width of the strip may be in the range of 100 to 300 microns, for example in the range of 150 to 250 microns, or in the range of 180 to 240 microns. Each of the inelastic yarns forming the band may have a width in the range of 10 to 20 microns. To this end, each of the non-elastic yarns may have a thickness in the range of 50 to 200 denier (d), for example, 70 to 180 denier (d) or 70 to 150 denier (d). The inelastic yarn is at least one selected from the group consisting of polyester, polyamide, polyacrylonitrile, polyethylene, polypropylene, polyurethane, a copolymer of monomers used to polymerize the above-mentioned polymers, and a mixture of the above-mentioned polymers. may include a multifilament yarn of non-absorbent material. If desired, the material of the inelastic yarn may be selected so that the covering layers 2 and 2a can be colonized by biological tissue.

The inelastic yarn may have a second elongation at break of 20% or less, for example, 18% or less, or 15% or less. The second elongation at break of the inelastic yarn is 50% or more, for example, 60% or more, 70% or more, 80% or more, 90% or more, or 100% or more of the first elongation at break of the elastic core yarn 1, 1a, 1b. Since it is smaller, the covering layer 2, 2a can effectively suppress the elongation of the elastic core yarn 1, 1a, 1b.

2 is a scanning electron microscope (SEM) of the surface of the surgical sutures 10 and 10a according to various embodiments of the present invention. Referring to this, various types of symmetrical coating layers formed on the surfaces of the surgical sutures 10 and 10a can be identified. The coating layer shown in Fig. 2(a) shows one coating layer (2, 2a) formed by braiding four bands symmetrically. The coating layer shown in Fig. 2(b) shows one coating layer (2, 2a) in which six bands are symmetrically braided. The coating layer shown in Fig. 2(c) shows one coating layer 2 and 2a formed by braiding symmetrically eight bands. The coating layer shown in Fig. 2(d) is a coating layer (2, 2a) consisting of two layers, each layer is a layer formed by braiding symmetrically four bands, therefore, the suture 10, The coating layers 2 and 2a of 10a) are finally formed by braiding 8 strands symmetrically. The bands are inelastic yarns made of polyethylene terephthalate (PET). As described above, in the sutures 10 and 10a for surgery according to various embodiments of the present invention, the covering layers 2 and 2a may include a plurality of layers, and the plurality of layers is, for example, one layer. , may be 2nd, 3rd or 4th floor.

The coating layer (2, 2a) can protect the sutures (10, 10a) from being cut by the sharp edges of the surgical equipment, and when the elastic core yarns (1, 1a, 1b) have a slippery surface like silicone elastic yarn By covering the slippery surface and applying an appropriate frictional force, it can be helped to be well pulled by a needle or the like, and, if necessary, a fabric piece can be easily manufactured using this suture.

3 is a scanning electron microscope (SEM) photograph of a cross section of a surgical suture 10a having two elastic core yarns 1a and 1b according to an embodiment of the present invention. Referring to FIG. 3 , the suture 10a includes two silicone elastic core yarns 1a and 1b extending in the longitudinal direction, and a coating layer 2a surrounding the silicone elastic core yarn 1a and 1b. .

The total diameter of the surgical suture 10a according to the present invention may be 0.3 to 5 mm, for example, 0.5 to 3 mm, 0.8 to 2 mm, 1 to 1.7 mm, 1 to 1.5 mm, or 1 to 0.9 mm. The overall diameter of the surgical suture 10a can be controlled using the number and thickness of the coating layers 2 and 2a, the thickness and the number of strands of the elastic core yarns 1, 1a, 1b, etc., through which the suture 10a ) thickness and mechanical properties such as tensile strength can be controlled.

In the surgical suture 10a according to the present invention, the non-elastic yarns constituting the elastic core yarns 1, 1a, 1b and the coating layer 2, 2a are preferably those having biocompatibility. In the present specification, biocompatibility means not causing an inflammatory reaction in the skin in a state of contact with human skin for a certain period of time, for example, 1 year, 6 months, or 1 month.

The surgical suture 10a according to the present invention is preferably stretchable to 100% or less of its original length, for example, 80% or less or 70% or less or more, and is elastic to its original length immediately when external force is removed. can be recovered

Next, a needle for a procedure according to embodiments of the present invention and a kit including the same will be described in more detail.

4 is a schematic perspective view showing the structure of a needle 100 for a procedure according to an embodiment of the present invention.

Referring to FIG. 4 , the surgical needle 100 is an atraumatic needle without a needle eye. The surgical needle 100 has a cylindrical body 20 extending in the longitudinal direction. A hollow portion 11 is formed inside the cylindrical body. A suture for a procedure may be inserted into the hollow part 11 . An opening 30 for introducing a suture into the hollow portion 11 from the outside of the body 20 is formed on one surface of the body 20 . A suture carrier 50 is provided in the hollow portion 11 inside the opening 30 . The suture carrier 50 is provided with a groove 32 for securely gripping the suture. The shape of the suture carrier 50 is not particularly limited as long as it can be inserted into the hollow portion 11 inside the body 20, but it can be smoothly transported across the hollow portion 11 to the insertion portion 21 It may have the shape of a cylinder having an outer diameter smaller than the inner diameter of the body 20 so as to be there. The suture inserted into the groove 32 and transported to the insertion portion 21 by the suture carrier 50 is not particularly limited, for example, a surgical suture according to certain embodiments of the present invention shown in FIG. 1 ( 10, 10a). The material of the body 20 may be a metal, for example, may be stainless steel. The material of the suture carrier 50 is not particularly limited, and may be plastic or metal, for example, stainless steel, polyethylene, polypropylene, or polyester.

The surgical needle 100 also has insertion portions 21 formed at both ends of the body 20 . In the present embodiment, the insertion portions 21 are formed at both ends of the body 20 , but the insertion portions 21 may be formed only at one end of the body 20 . The insertion unit 21 inserts the suture carried by the suture carrier 50 into the skin by cutting the skin of the recipient. The insertion part 21 may be in the form of a blade inclined at an appropriate inclination.

Referring back to FIG. 4 , the surgical needle 100 is provided with cutting grooves 40 at regular intervals along the longitudinal direction of the body 20 . The cutting groove 40 may be formed of a V-shaped blade. The cutting groove 400 is convenient when inserting the suture into the body 20, and the length can be adjusted by cutting the suture. Since the skin lifting procedure is a procedure that pulls the sagging skin by inserting a suture into the skin, the length of the suture is important according to the contour and area of the face. Therefore, it is possible to shorten the skin lifting procedure time by the presence of the cutting groove (40).

5 is a schematic perspective view of a kit 200 for a procedure including a suture 10 for a procedure and a needle 100 for a procedure according to an embodiment of the present invention.

Referring to FIG. 5 , the surgical kit 200 includes a surgical suture 10 and a surgical needle 100 . Since the surgical needle 100 shown in FIG. 5 is the same as the surgical needle 100 shown in FIG. 4, the description of the surgical needle 100 shown in this figure is the surgical needle shown in FIG. 100) applies as it is. In this figure, the surgical suture 10 is shown as a surgical suture 10 according to an embodiment of the present invention shown in FIG. 1( a ), but is not limited thereto, and the surgical suture 10 . For example, may be replaced with a suture 10a for a procedure according to another embodiment of the present invention shown in Figure 1 (b). In the kit 200 for the procedure, the suture 10 for the procedure is inserted into the groove 32 installed in the suture carrier 50 and securely gripped. As a result, when the suture carrier 50 moves to the insertion part 21 of either end, the suture 10 is also drawn by the carrier 50 and transported to the insertion part 21 . When the operator cuts the skin of the person to be treated and pushes the insertion part 21 in the form of a blade into the skin, the suture 10 transported to the insertion part 21 may also be pushed into the skin accordingly.

The stability of suture traction can be improved by using a suture having a surface structure by symmetrical braiding according to the present invention having the structure described above, a surgical needle including a suture carrier installed in a hollow part, or a kit including them. In addition, it is possible to reliably and reliably deliver the suture to the insertion portion, and effectively prevent problems in which the needle may be bent, bent, or cut during surgery.

Hereinafter, the present invention will be described in more detail using the following examples, but the present invention is not limited only to the following examples.

Example One

Polydimethylsiloxane (PDMS) polymer (manufacturer: Avantor, product number: MED-4750 High Consistency Elastomers) was extruded to prepare two types of elastic yarn filaments having a circular cross section of about 200 microns in diameter and about 340 microns in diameter.

A band of about 230 microns in width was formed by arranging 20 PET multifilament yarns having a fineness of 70 denier side by side. After arranging the two kinds of elastic yarn filaments side by side, braiding the two strips on the surface of the two kinds of elastic yarn filament cores to form a surface layer of about 700 microns in thickness, consisting of symmetrical braiding around the core was formed.

Various physical properties of this suture are shown in Table 1.

Example 2

Polydimethylsiloxane polymer (manufacturer: Avantor, product number: MED-4750 High Consistency Elastomers) was extruded to prepare two types of elastic yarn filaments having a circular cross section of about 400 microns in diameter and about 340 microns in diameter.

A band of about 230 microns in width was formed by arranging 20 PET multifilament yarns having a fineness of 70 denier side by side. After arranging the two kinds of elastic yarn filaments side by side, braiding the six strips on the surface of the two kinds of elastic yarn filament cores to form a surface layer of about 900 microns in thickness consisting of symmetrical braiding around the core. was formed.

Fig. 2(b) shows the symmetrical braiding surface layer of the suture for the procedure obtained in this way, and Fig. 3 shows the cross section of the suture for the procedure. Various physical properties of this suture are shown in Table 1.

Example 3

Polydimethylsiloxane polymer (manufacturer: Avantor, product number: MED-4750 High Consistency Elastomers) was extruded to prepare two types of elastic yarn filaments having a circular cross section of about 400 microns in diameter and about 340 microns in diameter.

A band of about 230 microns in width was formed by arranging 20 PET multifilament yarns having a fineness of 70 denier side by side. After arranging the two kinds of elastic yarn filaments side by side, braiding the 8 strips on the surface of the two kinds of elastic yarn filament cores to form a symmetrical braiding around the core. A surface layer of about 950 microns in thickness. was formed.

Figure 2(c) shows the symmetrical braiding surface layer of the surgical suture obtained in this way. Various physical properties of this suture are shown in Table 1.

Example 4

Polydimethylsiloxane polymer (manufacturer: Avantor, product number: MED-4750 High Consistency Elastomers) was extruded to prepare two types of elastic yarn filaments having a circular cross section of about 520 microns in diameter and about 340 microns in diameter.

A band of about 230 microns in width was formed by arranging 20 PET multifilament yarns having a fineness of 70 denier side by side. After arranging the two kinds of elastic yarn filaments side by side, braiding the 16 strips on the surface of the two kinds of elastic yarn filament cores to form a surface layer of about 1,000 microns in thickness consisting of symmetrical braiding around the core was formed.

Various physical properties of this suture are shown in Table 1.

Example 5

A suture was formed in the same manner as in Example 1, except that a surface layer having a thickness of about 800 microns was formed in two layers. Various physical properties of this suture are shown in Table 1.

Example 6

A suture was formed in the same manner as in Example 2, except that a surface layer having a thickness of about 950 microns was formed in two layers. Various physical properties of this suture are shown in Table 1.

Example 7

A suture was formed in the same manner as in Example 3, except that a surface layer having a thickness of about 1,000 microns was formed in two layers. Various physical properties of this suture are shown in Table 1.

Example 8

A suture was formed in the same manner as in Example 4, except that a surface layer having a thickness of about 1,100 microns was formed in two layers. Various physical properties of this suture are shown in Table 1.

Example 9

A suture was formed in the same manner as in Example 1 except that polyisoprene (PIP) rubber (manufacturer: KRATON, product number: Cariflex IR0310 KU) was used instead of polydimethylsiloxane polymer as a material for two types of elastic filaments. Various physical properties of this suture are shown in Table 1.

Example 10

A suture was formed in the same manner as in Example 2, except that polyisoprene rubber (manufacturer: KRATON, product number: Cariflex IR0310 KU) was used instead of polydimethylsiloxane polymer as a material for two types of elastic filaments. Various physical properties of this suture are shown in Table 1.

Example 11

A suture was formed in the same manner as in Example 4, except that polyisoprene rubber (manufacturer: KRATON, product number: Cariflex IR0310 KU) was used instead of polydimethylsiloxane polymer as a material for two types of elastic filaments. Various physical properties of this suture are shown in Table 1.

Example 12

A suture was formed in the same manner as in Example 1, except that a band obtained by using a nylon 6 multifilament yarn having a fineness of 150 denier instead of a PET multifilament yarn was used as a material for forming the surface layer. Various physical properties of this suture are shown in Table 1.

Example 13

A suture was formed in the same manner as in Example 2, except that a band obtained by using a nylon 6 multifilament yarn having a fineness of 150 denier instead of a PET multifilament yarn was used as a material for forming the surface layer. Various physical properties of this suture are shown in Table 1.

Example 14

A suture was formed in the same manner as in Example 4, except that a band obtained by using a nylon 6 multifilament yarn having a fineness of 150 denier instead of a PET multifilament yarn was used as a material for forming the surface layer. Various physical properties of this suture are shown in Table 1.

Example 15

Polydimethylsiloxane polymer (manufacturer: Avantor, product number: MED-4750 High Consistency Elastomers) was extruded to prepare three types of elastic yarn filaments having a circular cross section of about 200 microns in diameter, about 340 microns in diameter, and about 400 microns in diameter.

A band of about 230 microns in width was formed by arranging 20 PET multifilament yarns having a fineness of 70 denier side by side. After arranging the two kinds of elastic yarn filaments side by side, braiding the four bands on the surface of the three kinds of elastic yarn filament cores to form a symmetrical braiding around the core. A surface layer of about 950 microns in thickness. was formed.

Various physical properties of this suture are shown in Table 1.

Example 16

Polydimethylsiloxane polymer (manufacturer: Avantor, product number: MED-4750 High Consistency Elastomers) was extruded to prepare three types of elastic yarn filaments having a circular cross section of about 400 microns in diameter, about 340 microns in diameter, and about 520 microns in diameter.

A band of about 230 microns in width was formed by arranging 20 PET multifilament yarns having a fineness of 70 denier side by side. After arranging the two kinds of elastic yarn filaments side by side, braiding the 8 strips on the surface of the three kinds of elastic yarn filament cores to form a surface layer of about 1,100 microns in thickness consisting of symmetrical braiding around the core was formed.

Various physical properties of this suture are shown in Table 1.

Example 17

Polydimethylsiloxane polymer (manufacturer: Avantor, product number: MED-4750 High Consistency Elastomers) was extruded to prepare three types of elastic yarn filaments having a circular cross section of about 400 microns in diameter, about 340 microns in diameter, and about 520 microns in diameter.

A band of about 230 microns in width was formed by arranging 20 PET multifilament yarns having a fineness of 70 denier side by side. After arranging the two kinds of elastic yarn filaments side by side, braiding the 10 strips on the surface of the three kinds of elastic yarn filament cores to form a surface layer of about 1,300 microns in thickness consisting of symmetrical braiding around the core was formed.

Various physical properties of this suture are shown in Table 1.

Example 18

Polydimethylsiloxane polymer (manufacturer: Avantor, product number: MED-4750 High Consistency Elastomers) was extruded to prepare three types of elastic yarn filaments having a circular cross section of about 520 microns in diameter, about 340 microns in diameter, and about 600 microns in diameter. .

A band of about 230 microns in width was formed by arranging 20 PET multifilament yarns having a fineness of 70 denier side by side. After arranging the two kinds of elastic yarn filaments side by side, braiding 16 strands of the strip on the surface of the three kinds of elastic yarn filament cores to form a surface layer of about 1,500 microns in thickness consisting of symmetrical braiding around the core was formed.

Various physical properties of this suture are shown in Table 1.

comparative example One

Tensile strength was measured under the same conditions for a commercially available conventional surgical suture (manufacturer: KORPO, product number: E3.5J1.5R165). Table 1 shows various physical properties of the sutures of this comparative example.

Tensile test method

For the sutures prepared in Examples and Comparative Examples, the maximum load (N) and tensile strain were measured under a speed condition of 10 mm/min using a general UTM universal tester (manufacturer: Instron, model name: Instron 3343). The load at break was defined as the maximum load (N). The tensile test results of Examples and Comparative Examples in Table 1 are average values of the results of 5 tests for each sample.

biocompatibility test ( Biotoxicity test )

L-929 cell death and cell growth by applying the dilution extraction method or direct/indirect contact method to the suture test sample according to the Tests for in vitro cytotoxicity standard , and the degree of inhibition of proliferation was measured to confirm biocompatibility.

Shout
core yarn
Kinds Shout
core yarn
Number in the surface layer
multifilament
type of yarn the surface layer
forming
number of bands of the surface layer
number of floors Maximum load (N) Seal
strain
(%) Biotoxicity test
result Example 1 PDMS rubber 2 PET 2 One 15.3 907 No toxicity Example 2 PDMS rubber 2 PET 6 One 19.2 779 No toxicity Example 3 PDMS rubber 2 PET 8 One 25.3 635 No toxicity Example 4 PDMS rubber 2 PET 16 One 36.8 474 No toxicity Example 5 PDMS rubber 2 PET 2 2 17.4 834 No toxicity Example 6 PDMS rubber 2 PET 6 2 24.0 656 No toxicity Example 7 PDMS rubber 2 PET 8 2 37.1 533 No toxicity Example 8 PDMS rubber 2 PET 16 2 50.3 401 No toxicity Example 9 PIP rubber 2 PET 2 One 13.6 815 No toxicity Example 10 PIP rubber 2 PET 6 One 18.1 695 No toxicity Example 11 PIP rubber 2 PET 16 One 28.7 395 No toxicity Example 12 PDMS rubber 2 nylon 6 2 One 14.7 879 No toxicity Example 13 PDMS rubber 2 nylon 6 6 One 17.5 751 No toxicity Example 14 PDMS rubber 2 nylon 6 16 One 30.4 465 No toxicity Example 15 PDMS rubber 3 PET 4 One 18.28 936 No toxicity Example 16 PDMS rubber 3 PET 8 One 23.96 653 No toxicity Example 17 PDMS rubber 3 PET 10 One 36.51 611 No toxicity Example 18 PDMS rubber 3 PET 16 One 51.12 592 No toxicity Comparative Example 1 PDMS rubber - PET - - 24.37 627 No toxicity

Referring to Table 1, the suture of the present invention has significantly increased at least one of the maximum load and tensile strain compared to the conventional suture, and specifically, the maximum load (N) and tensile strain are about 10% or more under several conditions. and 30% or more significantly increased, and it was confirmed that there was no biotoxicity.

In the above, although the present invention has been described with reference to limited embodiments and drawings, the present invention is not limited thereto and various modifications and changes within the scope of the present invention by those of ordinary skill in the art to which the present invention belongs It goes without saying that transformation is possible.

1, 1a, 1b: elastic core yarn
10, 10a: surgical suture
100: surgical needle
20: body
11: Hollow
21: insertion part (blade)
30: opening
40: cutting groove
50: suture carrier

Claims (14)

A suture thread, the suture comprising:
Comprising an elastic core yarn extending in one direction and a coating layer surrounding the elastic core yarn,
The elastic core yarn is made of an elastic yarn containing at least one elastic polymer,
The coating layer includes a non-elastic yarn containing one or more inelastic polymers, a plurality of the inelastic yarns are arranged side by side to form a band, and the plurality of bands are braided to each other,
As for the bands, 2 strands, 4 strands, 6 strands, 8 strands, 10 strands, 12 strands, 14 strands or 16 strands of even-numbered strands are braided to each other to form the coating layer,
The elastic core yarn has a first elongation at break of 100% or more,
The inelastic yarn has a second elongation at break of 20% or less,
The second elongation at break is 50% or more smaller than the first elongation at break, so that the coating layer can suppress elongation of the elastic core yarn. The suture according to claim 1, wherein the elastic core yarn includes a plurality of strands. The suture according to claim 2, wherein the plurality of strands is selected from the range of 2 to 10 strands. The suture according to claim 1, wherein the covering layer comprises a plurality of layers. [Claim 5] The suture according to claim 4, wherein the plurality of layers are 1 layer, 2 layers, 3 layers, 4 layers, or 5 layers. The suture according to claim 1, wherein the width of the band is in the range of 100 to 300 microns, and each of the inelastic yarns constituting the band has a width in the range of 10 to 20 microns. The method of claim 1, wherein the elastic core yarn is silicone rubber, natural rubber, isoprene rubber, butyl rubber, chloroprene rubber, styrene-butadiene rubber (SBR), acrylo-butadiene rubber (NBR), polybutadiene rubber, ethylene propylene rubber, Sutures comprising at least one monofilament yarn selected from the group consisting of ethylene propylene diene rubber, polyacrylate rubber, and a mixture of the above-mentioned polymers. 2. The group of claim 1, wherein said inelastic yarn is made of polyester, polyamide, polyacrylonitrile, polyethylene, polypropylene, polyurethane, copolymers of monomers used to polymerize said polymers, and mixtures of said polymers. Sutures comprising a multifilament yarn of at least one non-absorbable material selected from A kit for a procedure comprising a suture and a needle for a procedure,
The surgical needle is
A cylindrical body extending in one direction, the body having a hollow portion formed inside the body;
an opening formed on one surface of the body to introduce the suture into the hollow portion from the outside of the body;
A suture carrier installed in the hollow portion inside the opening, the carrier having a groove for holding the suture; and
It includes; an insertion unit formed at one or both ends of the body to cut the skin and insert the suture delivered through the hollow portion by the carrier into the skin.
The suture is the suture according to any one of claims 1 to 8,
The suture is a kit for surgery that is coupled to the needle for the procedure by being inserted into the groove of the carrier. delete delete delete delete delete

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