KR20200079511A - Cd47 항원-결합 분자 - Google Patents
Cd47 항원-결합 분자 Download PDFInfo
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- KR20200079511A KR20200079511A KR1020207014915A KR20207014915A KR20200079511A KR 20200079511 A KR20200079511 A KR 20200079511A KR 1020207014915 A KR1020207014915 A KR 1020207014915A KR 20207014915 A KR20207014915 A KR 20207014915A KR 20200079511 A KR20200079511 A KR 20200079511A
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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| GBGB1720425.6A GB201720425D0 (en) | 2017-12-07 | 2017-12-07 | CD47 and CD33 antigen-binding molecules |
| GB1720426.4 | 2017-12-07 | ||
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| GB1720425.6 | 2017-12-07 | ||
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| KR20220039247A (ko) * | 2020-09-22 | 2022-03-29 | 비피진 주식회사 | 암 치료를 위한 cd47 바인더 및 리포좀 복합체 |
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| WO2019086573A1 (en) | 2017-11-01 | 2019-05-09 | Hummingbird Bioscience Holdings Pte. Ltd. | Cd47 antigen-binding molecules |
| KR20220047277A (ko) | 2019-07-16 | 2022-04-15 | 길리애드 사이언시즈, 인코포레이티드 | Hiv 백신, 및 이의 제조 및 사용 방법 |
| WO2021032174A1 (zh) * | 2019-08-21 | 2021-02-25 | 和铂医药(上海)有限责任公司 | 一种抗cd47抗原结合蛋白及其应用 |
| AU2020342192A1 (en) * | 2019-09-03 | 2022-04-21 | Akeso Biopharma, Inc | Anti-CD47 monoclonal antibody and use thereof |
| US11795223B2 (en) | 2019-10-18 | 2023-10-24 | Forty Seven, Inc. | Combination therapies for treating myelodysplastic syndromes and acute myeloid leukemia |
| NZ786589A (en) | 2019-10-31 | 2025-03-28 | Forty Seven Llc | Anti-cd47 and anti-cd20 based treatment of blood cancer |
| MX2022007930A (es) | 2019-12-24 | 2022-08-08 | Carna Biosciences Inc | Compuestos moduladores de diacilglicerol quinasa. |
| TWI832035B (zh) | 2020-02-14 | 2024-02-11 | 美商基利科學股份有限公司 | 結合ccr8之抗體及融合蛋白及其用途 |
| JP2023519346A (ja) | 2020-03-27 | 2023-05-10 | メンドゥス・ベスローテン・フェンノートシャップ | 養子細胞療法の有効性を増強するための白血病由来の改変細胞のエクスビボ（ｅｘ ｖｉｖｏ）使用 |
| TW202144407A (zh) * | 2020-04-02 | 2021-12-01 | 大陸商正大天晴藥業集團股份有限公司 | 結合cd47的抗原結合多肽及用途 |
| CN116133679A (zh) | 2020-06-30 | 2023-05-16 | 门德斯有限公司 | 白血病衍生细胞在卵巢癌疫苗中的用途 |
| WO2022090556A1 (en) | 2020-11-02 | 2022-05-05 | Hummingbird Bioscience Pte. Ltd. | Bcma/taci antigen-binding molecules |
| KR20230157388A (ko) | 2021-03-12 | 2023-11-16 | 멘두스 비.브이. | 백신접종의 방법 및 cd47 차단의 용도 |
| TW202302145A (zh) | 2021-04-14 | 2023-01-16 | 美商基利科學股份有限公司 | ＣＤ４７／ＳＩＲＰα結合及ＮＥＤＤ８活化酶Ｅ１調節次單元之共抑制以用於治療癌症 |
| EP4359389A1 (en) | 2021-06-23 | 2024-05-01 | Gilead Sciences, Inc. | Diacylglyercol kinase modulating compounds |
| JP7686091B2 (ja) | 2021-06-23 | 2025-05-30 | ギリアード サイエンシーズ， インコーポレイテッド | ジアシルグリセロールキナーゼ調節化合物 |
| CA3222277A1 (en) | 2021-06-23 | 2022-12-29 | Gilead Sciences, Inc. | Diacylglyercol kinase modulating compounds |
| AU2022298639C1 (en) | 2021-06-23 | 2025-07-17 | Gilead Sciences, Inc. | Diacylglyercol kinase modulating compounds |
| CN118055947A (zh) * | 2021-09-30 | 2024-05-17 | 正大天晴药业集团南京顺欣制药有限公司 | 联合治疗血液肿瘤的抗cd47抗体 |
| CA3234909A1 (en) | 2021-10-28 | 2023-05-04 | Gilead Sciences, Inc. | Pyridizin-3(2h)-one derivatives |
| JP2024541979A (ja) | 2021-10-29 | 2024-11-13 | ギリアード サイエンシーズ， インコーポレイテッド | Ｃｄ７３化合物 |
| CN118488946A (zh) | 2021-12-22 | 2024-08-13 | 吉利德科学公司 | Ikaros锌指家族降解剂及其用途 |
| KR20240125012A (ko) | 2021-12-22 | 2024-08-19 | 길리애드 사이언시즈, 인코포레이티드 | 이카로스 아연 핑거 패밀리 분해제 및 이의 용도 |
| TW202340168A (zh) | 2022-01-28 | 2023-10-16 | 美商基利科學股份有限公司 | Ｐａｒｐ７抑制劑 |
| DK4245756T3 (da) | 2022-03-17 | 2024-10-21 | Gilead Sciences Inc | Ikaros zinkfinger-familiens nedbrydere og anvendelse heraf |
| US20230355796A1 (en) | 2022-03-24 | 2023-11-09 | Gilead Sciences, Inc. | Combination therapy for treating trop-2 expressing cancers |
| TWI876305B (zh) | 2022-04-05 | 2025-03-11 | 美商基利科學股份有限公司 | 用於治療結腸直腸癌之組合療法 |
| IL316058A (en) | 2022-04-21 | 2024-11-01 | Gilead Sciences Inc | Compounds modulate KRAS G12D |
| CR20240570A (es) | 2022-07-01 | 2025-03-03 | Gilead Sciences Inc | Compuestos de cd73 |
| AU2023307100A1 (en) | 2022-07-12 | 2025-01-02 | Gilead Sciences, Inc. | Hiv immunogenic polypeptides and vaccines and uses thereof |
| WO2024064668A1 (en) | 2022-09-21 | 2024-03-28 | Gilead Sciences, Inc. | FOCAL IONIZING RADIATION AND CD47/SIRPα DISRUPTION ANTICANCER COMBINATION THERAPY |
| CN116063579A (zh) * | 2022-11-17 | 2023-05-05 | 安徽医科大学 | 一种靶向人cd47的嵌合抗原受体、表达嵌合抗原受体的巨噬细胞及其应用 |
| KR20250122479A (ko) | 2022-12-22 | 2025-08-13 | 길리애드 사이언시즈, 인코포레이티드 | Prmt5 억제제 및 이의 용도 |
| CN116004636B (zh) * | 2023-01-10 | 2024-03-12 | 广西师范大学 | 一种不结合红细胞的差异化cd47核酸适体及其应用 |
| US20240383922A1 (en) | 2023-04-11 | 2024-11-21 | Gilead Sciences, Inc. | KRAS Modulating Compounds |
| AU2024259556A1 (en) | 2023-04-21 | 2025-10-23 | Gilead Sciences, Inc. | Prmt5 inhibitors and uses thereof |
| WO2025006720A1 (en) | 2023-06-30 | 2025-01-02 | Gilead Sciences, Inc. | Kras modulating compounds |
| US20250100998A1 (en) | 2023-07-26 | 2025-03-27 | Gilead Sciences, Inc. | Parp7 inhibitors |
| WO2025024663A1 (en) | 2023-07-26 | 2025-01-30 | Gilead Sciences, Inc. | Parp7 inhibitors |
| WO2025054347A1 (en) | 2023-09-08 | 2025-03-13 | Gilead Sciences, Inc. | Kras g12d modulating compounds |
| US20250109147A1 (en) | 2023-09-08 | 2025-04-03 | Gilead Sciences, Inc. | Kras g12d modulating compounds |
| US20250154172A1 (en) | 2023-11-03 | 2025-05-15 | Gilead Sciences, Inc. | Prmt5 inhibitors and uses thereof |
| US20250230168A1 (en) | 2023-12-22 | 2025-07-17 | Gilead Sciences, Inc. | Azaspiro wrn inhibitors |
| WO2025245003A1 (en) | 2024-05-21 | 2025-11-27 | Gilead Sciences, Inc. | Prmt5 inhibitors and uses thereof |
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| US8758750B2 (en) | 2009-09-15 | 2014-06-24 | The Board Of Trustees Of The Leland Stanford Junior University | Synergistic anti-CD47 therapy for hematologic cancers |
| SG194176A1 (en) | 2011-05-27 | 2013-12-30 | Glaxo Group Ltd | Bcma (cd269/tnfrsf17) -binding proteins |
| US9045541B2 (en) | 2012-02-06 | 2015-06-02 | Inhibrx Llc | CD47 antibodies and methods of use thereof |
| RU2019118257A (ru) | 2012-12-03 | 2019-06-24 | Новиммун С.А. | Анти-cd47 антитела и способы их применения |
| MX2015007446A (es) | 2012-12-12 | 2015-12-07 | Vasculox Inc | Anticuerpos terapeuticos para cd47. |
| WO2014121093A1 (en) | 2013-01-31 | 2014-08-07 | Thomas Jefferson University | Fusion proteins that facilitate cancer cell destruction |
| EP3110838B1 (en) | 2014-02-27 | 2019-06-26 | UCL Business Plc. | April variants |
| CN104804093A (zh) | 2015-05-27 | 2015-07-29 | 江苏春申堂药业有限公司 | 一种针对cd47的单域抗体 |
| MX2018003374A (es) * | 2015-09-18 | 2018-11-09 | Arch Oncology Inc | Anticuerpos terapeuticos cd47. |
| EP3165536A1 (en) * | 2015-11-09 | 2017-05-10 | Ludwig-Maximilians-Universität München | Trispecific molecule combining specific tumor targeting and local immune checkpoint inhibition |
| MX2018008558A (es) * | 2016-01-11 | 2019-05-06 | Forty Seven Inc | Anticuerpos monoclonales anti-cd47 humanizados, de raton, o quimericos. |
| EP3454900A4 (en) | 2016-05-09 | 2020-01-29 | Celgene Corporation | CD47 ANTIBODIES AND METHODS OF USE |
| CN105950561A (zh) | 2016-05-26 | 2016-09-21 | 江苏杰晟生物科技有限公司 | 一种靶向乳腺癌干细胞的双特异性嵌合抗原受体基因修饰的t淋巴细胞的制备方法及其产品 |
| CA2999058C (en) * | 2016-10-20 | 2024-03-12 | I-Mab | Novel cd47 monoclonal antibodies and uses thereof |
| EP3615068A1 (en) | 2017-04-28 | 2020-03-04 | Novartis AG | Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor |
| WO2019086573A1 (en) | 2017-11-01 | 2019-05-09 | Hummingbird Bioscience Holdings Pte. Ltd. | Cd47 antigen-binding molecules |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20220039247A (ko) * | 2020-09-22 | 2022-03-29 | 비피진 주식회사 | 암 치료를 위한 cd47 바인더 및 리포좀 복합체 |
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| US20220298254A1 (en) | 2022-09-22 |
| WO2019086573A1 (en) | 2019-05-09 |
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