KR20200035569A - Beverage Composition Comprising Hovenia dulcis Thunberg Fruit for Treating Hangover - Google Patents
Beverage Composition Comprising Hovenia dulcis Thunberg Fruit for Treating Hangover Download PDFInfo
- Publication number
- KR20200035569A KR20200035569A KR1020180114745A KR20180114745A KR20200035569A KR 20200035569 A KR20200035569 A KR 20200035569A KR 1020180114745 A KR1020180114745 A KR 1020180114745A KR 20180114745 A KR20180114745 A KR 20180114745A KR 20200035569 A KR20200035569 A KR 20200035569A
- Authority
- KR
- South Korea
- Prior art keywords
- weight
- composition
- extract
- parts
- hangover
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 105
- 206010019133 Hangover Diseases 0.000 title claims abstract description 67
- 235000013361 beverage Nutrition 0.000 title claims abstract description 50
- 244000010000 Hovenia dulcis Species 0.000 title abstract description 4
- 235000008584 Hovenia dulcis Nutrition 0.000 title abstract description 4
- 239000000284 extract Substances 0.000 claims abstract description 40
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 26
- 108091005804 Peptidases Proteins 0.000 claims abstract description 9
- 229930003231 vitamin Natural products 0.000 claims abstract description 9
- 239000011782 vitamin Substances 0.000 claims abstract description 9
- 235000013343 vitamin Nutrition 0.000 claims abstract description 9
- 229940088594 vitamin Drugs 0.000 claims abstract description 9
- 235000003599 food sweetener Nutrition 0.000 claims abstract description 8
- 239000003765 sweetening agent Substances 0.000 claims abstract description 8
- 150000003722 vitamin derivatives Chemical class 0.000 claims abstract description 8
- 239000008213 purified water Substances 0.000 claims abstract description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 43
- 239000000796 flavoring agent Substances 0.000 claims description 19
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 12
- 239000004365 Protease Substances 0.000 claims description 8
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims description 8
- 239000007788 liquid Substances 0.000 claims description 8
- 235000011194 food seasoning agent Nutrition 0.000 claims description 7
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 6
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims description 6
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 6
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 6
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 claims description 6
- 239000008103 glucose Substances 0.000 claims description 6
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 claims description 6
- 229930091371 Fructose Natural products 0.000 claims description 5
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims description 5
- 239000005715 Fructose Substances 0.000 claims description 5
- 240000004670 Glycyrrhiza echinata Species 0.000 claims description 5
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 claims description 5
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims description 5
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 claims description 5
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 claims description 5
- 238000000605 extraction Methods 0.000 claims description 5
- 229940010454 licorice Drugs 0.000 claims description 5
- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 claims description 5
- 229940013618 stevioside Drugs 0.000 claims description 5
- 235000019202 steviosides Nutrition 0.000 claims description 5
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims description 4
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 229940124568 digestive agent Drugs 0.000 claims description 4
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims description 3
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims description 3
- 239000004278 EU approved seasoning Substances 0.000 claims description 3
- 229930003779 Vitamin B12 Natural products 0.000 claims description 3
- 229930003268 Vitamin C Natural products 0.000 claims description 3
- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 claims description 3
- 239000002904 solvent Substances 0.000 claims description 3
- 235000019163 vitamin B12 Nutrition 0.000 claims description 3
- 239000011715 vitamin B12 Substances 0.000 claims description 3
- 235000019154 vitamin C Nutrition 0.000 claims description 3
- 239000011718 vitamin C Substances 0.000 claims description 3
- 235000015165 citric acid Nutrition 0.000 claims description 2
- 230000002500 effect on skin Effects 0.000 claims description 2
- 235000013355 food flavoring agent Nutrition 0.000 claims description 2
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 claims 3
- 241001233061 earthworms Species 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 abstract description 17
- 235000019629 palatability Nutrition 0.000 abstract description 12
- 230000000694 effects Effects 0.000 abstract description 11
- 235000013399 edible fruits Nutrition 0.000 abstract description 8
- 230000008901 benefit Effects 0.000 abstract description 6
- 102000035195 Peptidases Human genes 0.000 abstract 1
- 235000013409 condiments Nutrition 0.000 abstract 1
- 230000001079 digestive effect Effects 0.000 abstract 1
- 239000012676 herbal extract Substances 0.000 description 19
- 238000000855 fermentation Methods 0.000 description 18
- 230000004151 fermentation Effects 0.000 description 18
- 235000019634 flavors Nutrition 0.000 description 17
- 238000000034 method Methods 0.000 description 17
- 235000015092 herbal tea Nutrition 0.000 description 14
- IKHGUXGNUITLKF-UHFFFAOYSA-N Acetaldehyde Chemical compound CC=O IKHGUXGNUITLKF-UHFFFAOYSA-N 0.000 description 12
- 230000000052 comparative effect Effects 0.000 description 11
- 238000002474 experimental method Methods 0.000 description 10
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 10
- 235000019640 taste Nutrition 0.000 description 10
- 238000011156 evaluation Methods 0.000 description 8
- 239000008280 blood Substances 0.000 description 7
- 210000004369 blood Anatomy 0.000 description 7
- 230000035622 drinking Effects 0.000 description 7
- 235000013305 food Nutrition 0.000 description 6
- 238000002360 preparation method Methods 0.000 description 6
- 241000894006 Bacteria Species 0.000 description 5
- 210000004207 dermis Anatomy 0.000 description 5
- 239000004310 lactic acid Substances 0.000 description 5
- 235000014655 lactic acid Nutrition 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 241000361919 Metaphire sieboldi Species 0.000 description 4
- 235000019658 bitter taste Nutrition 0.000 description 4
- 235000012907 honey Nutrition 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 3
- 108090000790 Enzymes Proteins 0.000 description 3
- 241000699670 Mus sp. Species 0.000 description 3
- 235000002789 Panax ginseng Nutrition 0.000 description 3
- 241000700159 Rattus Species 0.000 description 3
- 210000004556 brain Anatomy 0.000 description 3
- 238000000354 decomposition reaction Methods 0.000 description 3
- 230000002401 inhibitory effect Effects 0.000 description 3
- 229940068140 lactobacillus bifidus Drugs 0.000 description 3
- 210000004185 liver Anatomy 0.000 description 3
- 230000004060 metabolic process Effects 0.000 description 3
- 239000002994 raw material Substances 0.000 description 3
- 230000001953 sensory effect Effects 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 231100000419 toxicity Toxicity 0.000 description 3
- 230000001988 toxicity Effects 0.000 description 3
- 244000003416 Asparagus officinalis Species 0.000 description 2
- 235000005340 Asparagus officinalis Nutrition 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- 240000001046 Lactobacillus acidophilus Species 0.000 description 2
- 241000191996 Pediococcus pentosaceus Species 0.000 description 2
- 244000057717 Streptococcus lactis Species 0.000 description 2
- 244000269722 Thea sinensis Species 0.000 description 2
- 150000001298 alcohols Chemical class 0.000 description 2
- 108010081577 aldehyde dehydrogenase (NAD(P)+) Proteins 0.000 description 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 2
- 230000037396 body weight Effects 0.000 description 2
- 235000012206 bottled water Nutrition 0.000 description 2
- 229910052571 earthenware Inorganic materials 0.000 description 2
- 239000003205 fragrance Substances 0.000 description 2
- 235000021109 kimchi Nutrition 0.000 description 2
- 235000021374 legumes Nutrition 0.000 description 2
- 229940069445 licorice extract Drugs 0.000 description 2
- 210000005229 liver cell Anatomy 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 235000019997 soju Nutrition 0.000 description 2
- 229940058015 1,3-butylene glycol Drugs 0.000 description 1
- VZSRBBMJRBPUNF-UHFFFAOYSA-N 2-(2,3-dihydro-1H-inden-2-ylamino)-N-[3-oxo-3-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)propyl]pyrimidine-5-carboxamide Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)C(=O)NCCC(N1CC2=C(CC1)NN=N2)=O VZSRBBMJRBPUNF-UHFFFAOYSA-N 0.000 description 1
- YLZOPXRUQYQQID-UHFFFAOYSA-N 3-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)-1-[4-[2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidin-5-yl]piperazin-1-yl]propan-1-one Chemical compound N1N=NC=2CN(CCC=21)CCC(=O)N1CCN(CC1)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F YLZOPXRUQYQQID-UHFFFAOYSA-N 0.000 description 1
- 102000007698 Alcohol dehydrogenase Human genes 0.000 description 1
- 108010021809 Alcohol dehydrogenase Proteins 0.000 description 1
- 244000291564 Allium cepa Species 0.000 description 1
- 235000002732 Allium cepa var. cepa Nutrition 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- DKPFZGUDAPQIHT-UHFFFAOYSA-N Butyl acetate Natural products CCCCOC(C)=O DKPFZGUDAPQIHT-UHFFFAOYSA-N 0.000 description 1
- 241000675108 Citrus tangerina Species 0.000 description 1
- 241000555678 Citrus unshiu Species 0.000 description 1
- 235000001543 Corylus americana Nutrition 0.000 description 1
- 240000007582 Corylus avellana Species 0.000 description 1
- 235000007466 Corylus avellana Nutrition 0.000 description 1
- 235000009917 Crataegus X brevipes Nutrition 0.000 description 1
- 235000013204 Crataegus X haemacarpa Nutrition 0.000 description 1
- 235000009685 Crataegus X maligna Nutrition 0.000 description 1
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 description 1
- 235000009486 Crataegus bullatus Nutrition 0.000 description 1
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 description 1
- 235000009682 Crataegus limnophila Nutrition 0.000 description 1
- 240000000171 Crataegus monogyna Species 0.000 description 1
- 235000004423 Crataegus monogyna Nutrition 0.000 description 1
- 235000002313 Crataegus paludosa Nutrition 0.000 description 1
- 235000009840 Crataegus x incaedua Nutrition 0.000 description 1
- 240000008067 Cucumis sativus Species 0.000 description 1
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 1
- 206010012335 Dependence Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 241000194032 Enterococcus faecalis Species 0.000 description 1
- 241000220485 Fabaceae Species 0.000 description 1
- GYHNNYVSQQEPJS-UHFFFAOYSA-N Gallium Chemical compound [Ga] GYHNNYVSQQEPJS-UHFFFAOYSA-N 0.000 description 1
- 208000018522 Gastrointestinal disease Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 241000186660 Lactobacillus Species 0.000 description 1
- 244000199866 Lactobacillus casei Species 0.000 description 1
- 235000013958 Lactobacillus casei Nutrition 0.000 description 1
- 241001647418 Lactobacillus paralimentarius Species 0.000 description 1
- 240000006024 Lactobacillus plantarum Species 0.000 description 1
- 241001674646 Lepeophtheirus bifidus Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 240000004371 Panax ginseng Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 241000192001 Pediococcus Species 0.000 description 1
- 244000046146 Pueraria lobata Species 0.000 description 1
- 235000010575 Pueraria lobata Nutrition 0.000 description 1
- 241000219100 Rhamnaceae Species 0.000 description 1
- 235000004789 Rosa xanthina Nutrition 0.000 description 1
- 241000220222 Rosaceae Species 0.000 description 1
- 241000320380 Silybum Species 0.000 description 1
- 235000010841 Silybum marianum Nutrition 0.000 description 1
- 235000014897 Streptococcus lactis Nutrition 0.000 description 1
- 241000500332 Tetragenococcus halophilus Species 0.000 description 1
- IKHGUXGNUITLKF-XPULMUKRSA-N acetaldehyde Chemical compound [14CH]([14CH3])=O IKHGUXGNUITLKF-XPULMUKRSA-N 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 210000000577 adipose tissue Anatomy 0.000 description 1
- 125000003158 alcohol group Chemical group 0.000 description 1
- 235000013334 alcoholic beverage Nutrition 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000013527 bean curd Nutrition 0.000 description 1
- 230000036765 blood level Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 235000019437 butane-1,3-diol Nutrition 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 239000000287 crude extract Substances 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000000593 degrading effect Effects 0.000 description 1
- 235000015872 dietary supplement Nutrition 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000005281 excited state Effects 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- 235000013373 food additive Nutrition 0.000 description 1
- 239000002778 food additive Substances 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 229910052733 gallium Inorganic materials 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 235000020710 ginseng extract Nutrition 0.000 description 1
- 235000009569 green tea Nutrition 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- FUZZWVXGSFPDMH-UHFFFAOYSA-N hexanoic acid Chemical compound CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 description 1
- 229960004592 isopropanol Drugs 0.000 description 1
- 229940039696 lactobacillus Drugs 0.000 description 1
- 229940017800 lactobacillus casei Drugs 0.000 description 1
- 230000033001 locomotion Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 239000012046 mixed solvent Substances 0.000 description 1
- 201000003152 motion sickness Diseases 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- SFMJNHNUOVADRW-UHFFFAOYSA-N n-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[h][1,6]naphthyridin-1-yl]-2-methylphenyl]prop-2-enamide Chemical compound C1=C(NC(=O)C=C)C(C)=CC=C1N1C(=O)C=CC2=C1C1=CC(C=3C=CC(NS(C)(=O)=O)=CC=3)=CC=C1N=C2 SFMJNHNUOVADRW-UHFFFAOYSA-N 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 229920001542 oligosaccharide Polymers 0.000 description 1
- 150000002482 oligosaccharides Chemical class 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 210000004798 organs belonging to the digestive system Anatomy 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- 230000007958 sleep Effects 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 235000013616 tea Nutrition 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
- A23L2/56—Flavouring or bittering agents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
- A23L2/60—Sweeteners
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/334—Foods, ingredients or supplements having a functional effect on health treating the effects of consuming alcohol, narcotics or other addictive behavior, e.g. treating hangover or reducing blood alcohol levels
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/02—Acid
- A23V2250/032—Citric acid
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/20—Natural extracts
- A23V2250/21—Plant extracts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/24—Non-sugar sweeteners
- A23V2250/262—Stevioside
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/60—Sugars, e.g. mono-, di-, tri-, tetra-saccharides
- A23V2250/61—Glucose, Dextrose
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/70—Vitamins
- A23V2250/704—Vitamin B
- A23V2250/706—Vitamin B12
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/70—Vitamins
- A23V2250/708—Vitamin C
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2300/00—Processes
- A23V2300/14—Extraction
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Non-Alcoholic Beverages (AREA)
Abstract
Description
본 발명은 지구자를 포함하는 숙취 해소용 음료 조성물에 관한 것으로, 보다 상세하게는 지구자, 소화제 조성물, 단백질분해효소 조성물 및 비타민을 포함하는 숙취 해소용 음료 조성물에 관한 것이다.The present invention relates to a beverage composition for relieving a hangover comprising a terrestrial, and more particularly, to a beverage composition for relieving a hangover comprising a terrestrial, a digestive agent composition, a protease composition and a vitamin.
회식과 접대가 잦고 스트레스가 많은 현대인들에게 음주 기회가 날로 증가하고 있다. 알코올은 뇌의 억제중추를 마비시켜 섭취 시 외관상 흥분한 상태를 보여주는데, 의식과 동작을 억제하고 수면 및 마취 효과가 현대인들의 스트레스 해소를 위한 주요한 기호식품으로 이용되고 있다. 정상적인 알코올 대사과정에서 알코올이 체내로 유입되면 물에 잘 녹는 알코올의 특성에 의해 위장관에서 흡수되어 혈류를 통해 뇌와 간을 포함한 신체 각 조직에 분포된다. 간세포에는 알콜탈수소화 효소(알콜 분해 효소)가 있어 알콜을 아세트알데히드로 산화시키고, 아세트알데히드는 간세포에 있는 아세트알데히드 탈수소화 효소에 의해 초산으로 분해되어 전신의 근육이나 지방조직으로 옮겨진 후, 최종적으로 탄산가스와 물로 분해된다. 간에서 대사되지 않은 알코올은 혈중에 남아있다가 호흡기, 피부 또는 소변으로 배출된다. 알코올은 섭취량이나 혈중 농도에 관계없이 매 시간당 일정량만 대사되며, 알코올의 대사에 관여하는 효소의 역가나 농도는 각 개인의 유전적인 정도나 환경적인 요인에 의해 결정되며, 각 개인의 성별, 연령, 체중, 영양상태 및 신체 조건에 따라 영향을 받게 된다.Drinking opportunities are increasing day by day for modern people who have frequent drinking and entertainment and stress. Alcohol paralyzes the brain's inhibitory centers and, when ingested, shows an apparently excited state. It suppresses consciousness and movement, and sleep and anesthesia effects are used as major foods to relieve stress in modern people. When alcohol enters the body during normal alcohol metabolism, it is absorbed from the gastrointestinal tract by the nature of alcohol that dissolves well in water and distributed through bloodstream to each tissue of the body, including the brain and liver. Liver cells have an alcohol dehydrogenase (alcohol degrading enzyme), which oxidizes alcohol to acetaldehyde, and acetaldehyde is decomposed into acetic acid by acetaldehyde dehydrogenase in the liver cells, which is then transferred to the muscles or adipose tissue of the whole body, and finally Decomposes into carbon dioxide gas and water. Alcohol that is not metabolized in the liver remains in the blood and is excreted in the respiratory, skin, or urine. Alcohol is metabolized only a certain amount per hour, regardless of the intake or blood level, and the titer or concentration of enzymes involved in the metabolism of alcohol is determined by the genetic or environmental factors of each individual. It is affected by body weight, nutrition, and physical condition.
한편 아세트알데히드 탈수소화 효소에는 아세트알데히드가 저농도이더라도 산화를 개시하는 Ⅱ형과 아세트알데히드가 고농도로 되지 않으면 작용을 하지 않은 Ⅰ형이 있다. 동양인은 일반적으로 Ⅱ형 아세트알데히드효소가 결핍 또는 부족하기 때문에 아세트알데히드의 산화가 느리며 산화되지 아니한 아세트알데히드 및/또는 알코올의 독성에 의하여 정상적인 신진대사가 방해받아 여러 숙취 현상을 느끼게 된다. 이와 같이 음주는 일시적으로 두근거림, 두통, 갈증, 멀미, 위장장애, 설사 등의 숙취현상을 유발하며, 중독증으로 발전할 수도 있고, 뇌 등의 중추 신경계 뿐 아니라 소화기관 및 간 등의 대사기관도 손상시키는 문제가 있다. 최근들어, 알코올 및 알코올 대사물의 독성을 경감시키거나 독성의 발현을 저해하는 것에 의해 알코올이 인체에 미치는 영향을 최소화할 수 있는 물질들에 대한 연구와 실험이 진행되고 있다. On the other hand, there are two types of acetaldehyde dehydrogenases that do not function unless the acetaldehyde is at a high concentration, and the type II which initiates oxidation even when the acetaldehyde is at a low concentration. Because Asians generally lack or lack type II acetaldehyde enzymes, the oxidation of acetaldehyde is slow and normal metabolism is disturbed by the toxicity of non-oxidized acetaldehyde and / or alcohol, causing various hangover symptoms. As such, drinking temporarily causes hangovers such as palpitations, headaches, thirst, motion sickness, gastrointestinal disorders, and diarrhea, and may develop into addiction, metabolic organs such as the digestive organs and liver as well as the central nervous system of the brain There is a problem of damage. Recently, studies and experiments have been conducted on substances that can minimize the effects of alcohol on the human body by reducing the toxicity of alcohol and alcohol metabolites or inhibiting the expression of toxicity.
KR 공개특허 10-2011-0129534(발명의 명칭 : 숙취 해소용 음료 조성물)에서는 홍삼추출물, 혼합과일추출물 및 혼합식물추출물을 포함하는 숙취 해소용 음료 조성물을 제공하고 있고, KR Patent Publication 10-2011-0129534 (invention name: beverage composition for relieving hangover) provides a beverage composition for relieving hangover, including red ginseng extract, mixed fruit extract and mixed plant extract,
KR 공개특허 10-2000-0071310(발명의 명칭 : 천연 생약제 추출물을 포함하는 숙취해소용 조성물 및 이를 유효성분으로 함유하는 건강보조식품)호에서는 두충, 홍삼, 결명자 및 황연 추출물 등을 포함하는 숙취해소용 음료 조성물을 제공하고 있으며, KR Patent Publication No. 10-2000-0071310 (Invention name: Composition for relieving hangover containing natural herbal extracts and health supplement food containing it as an active ingredient) Hangover containing Duchung, red ginseng, ginseng and yellow lead extract We provide a small beverage composition,
KR 공개특허 10-2002-0079429(발명의 명칭 : 숙취해소용 조성물)호에서는 아스파라거스, 녹차, 양파 및 매실 추출물 등을 포함하는 숙취해소용 음료 조성물을 제공하고 있다.KR Patent Publication No. 10-2002-0079429 (invention name: composition for releasing hangover) provides a beverage composition for releasing hangover including asparagus, green tea, onion, and plum extract.
상기 숙취 해소용 음료 조성물은 뛰어난 숙취 해소 효과를 나타내나 그 맛이 매우 떫고, 홍삼, 아스파라거스 또는 밀크씨슬 등 고가의 원료를 포함하고 있어, 제품 양산 과정에서 비용 부담이 증가하는 문제가 존재한다.The beverage composition for hangover relieving exhibits an excellent hangover relieving effect, but its taste is very strong and contains expensive raw materials such as red ginseng, asparagus, or milk thistle, and there is a problem in that the cost burden increases during product mass production.
본 명세서 전체에 걸쳐 다수의 논문 및 특허문헌이 참조되고 그 인용이 표시되어 있다. 인용된 논문 및 특허문헌의 개시 내용은 그 전체로서 본 명세서에 참조로 삽입되어 본 발명이 속하는 기술 분야의 수준 및 본 발명의 내용이 보다 명확하게 설명된다.Throughout this specification, a number of papers and patent documents are referenced and their citations are indicated. The disclosures of cited papers and patent documents are incorporated by reference into the present specification as a whole, and the level of the technical field to which the present invention pertains and the content of the present invention are more clearly described.
본 발명자들은 저렴한 가격에 제조가 가능하면서도 숙취해소 능력이 탁월한 숙취해소음료 조성물을 개발하고자 예의 연구 노력하였다. 그 결과, 지구자, 소화제 조성물, 단백질분해효소 조성물 및 비타민을 혼합하여 숙취해소음료 조성물을 제조할 경우 기호성이 탁월하고, 숙취해소 효과가 현저하며, 기존의 숙취해소음료 조성물에 비해 저렴한 가격에 숙취해소음료를 제조할 수 있다는 사실을 발견하여 본 발명을 완성하였다.The present inventors have made extensive efforts to develop a hangover-drinking beverage composition that is capable of manufacturing at an affordable price and has excellent hangover-releasing ability. As a result, when a hangover-reducing beverage composition is prepared by mixing the earthworm, a digestive agent composition, a protease composition, and a vitamin, the palatability is excellent, the hangover-relieving effect is remarkable, and the hangover is cheaper than the conventional hangover-releasing beverage composition. The present invention was completed by discovering the fact that it is possible to manufacture a quenched beverage.
따라서 본 발명의 목적은 지구자를 포함하는 숙취해소음료 조성물을 제공하는데 있다.Accordingly, an object of the present invention is to provide a hangover-reducing beverage composition comprising a terminator.
또한, 본 발명의 다른 목적은 상기 지구자를 포함하는 숙취해소음료 조성물의 제조방법을 제공하는데 있다.In addition, another object of the present invention is to provide a method for producing a hangover-drinking beverage composition comprising the earth.
본 발명의 다른 목적 및 이점은 하기의 발명의 상세한 설명, 청구범위 및 도면에 의해 보다 명확하게 된다.Other objects and advantages of the present invention will become more apparent from the following detailed description of the invention, claims and drawings.
본 발명은 숙취해소음료 조성물 제공한다.The present invention provides a hangover drink composition.
본 발명자들은 저렴한 가격에 제조가 가능하면서도 숙취해소 능력이 탁월한 숙취해소음료 조성물을 개발하고자 예의 연구 노력하였다. 그 결과, 지구자, 소화제 조성물, 단백질분해효소 조성물 및 비타민을 혼합하여 숙취해소음료 조성물을 제조할 경우 기호성이 탁월하고, 숙취해소 효과가 현저하며, 기존의 숙취해소음료 조성물에 비해 저렴한 가격에 숙취해소음료를 제조할 수 있다는 사실을 확인하였다.The present inventors have made extensive efforts to develop a hangover-drinking beverage composition that is capable of manufacturing at an affordable price and has excellent hangover-releasing ability. As a result, when a hangover-reducing beverage composition is prepared by mixing the earthworm, a digestive agent composition, a protease composition, and a vitamin, the palatability is excellent, the hangover-relieving effect is remarkable, and the hangover is cheaper than the conventional hangover-releasing beverage composition. It has been confirmed that a quenched beverage can be produced.
본 발명의 일 양태에 따르면, 본 발명은 다음을 포함하는 지구자를 포함하는 숙취해소용음료 조성물을 제공한다: (a) 상기 조성물 총 중량을 기준으로 지구자 추출물, 상기 지구자 추출물 100 중량부를 기준으로 50 중량부 내지 100 중량부의 소화제 조성물, 20 중량부 내지 30 중량부의 단백질분해효소 조성물 및 1 중량부 내지 5 중량부의 비타민을 포함하는 혼합물 5-20 중량%; (b) 감미료(甘味料) 및 조미료(調味料) 5-20 중량%; 및 (c) 잔량의 정제수.According to an aspect of the present invention, the present invention provides a beverage composition for releasing a hangover comprising a terrestrial comprising: (a) a terrestrial extract based on the total weight of the composition, based on 100 parts by weight of the terrestrial extract 5-20 parts by weight of a mixture comprising 50 parts by weight to 100 parts by weight of an extinguishing agent composition, 20 parts by weight to 30 parts by weight of a protease composition and 1 part by weight to 5 parts by weight of vitamin; (b) 5-20% by weight of sweeteners and seasonings; And (c) a residual amount of purified water.
본 명세서에서 사용하는 용어‘지구자’는 갈매나무과의 헛개나무(Hovenia dulcis Thunb.)의 과병을 가진 열매 또는 씨를 의미할 수 있다.As used herein, the term 'earthworm' may mean a fruit or seed having a fruit disease of the buckthorn family (Hovenia dulcis Thunb.).
본 명세서에서 사용하는 용어‘창출’은 삽주의 뿌리 열매를 의미할 수 있다.The term 'creation' used in this specification may mean the root fruit of shovel.
본 명세서에서 사용하는 용어‘진피’는 운향과의 귤(Citrus unshiu Markovich) 또는 동속 근연식물의 성숙한 과피를 의미할 수 있다.The term 'dermis' as used herein may mean a mature peel of a tangerine (Citrus unshiu Markovich) or a related plant in the family.
본 명세서에서 사용하는 용어‘갈화’는 칡 Pueraria lobata Ohwi (콩과 Leguminosae)의 꽃봉오리 또는 막 피기 시작한 꽃을 의미할 수 있다.As used herein, the term ‘galhwa’ may mean a bud of 칡 Pueraria lobata Ohwi (legume Leguminosae) or a flower that has just begun to bloom.
본 명세서에서 사용하는 용어‘감초’는 쌍떡잎식물 장미목 콩과의 여러해살이 약용식물을 의미할 수 있다.The term 'licorice' used in the present specification may mean a perennial medicinal plant of the dicotyledonous rosaceae legume.
본 명세서에서 사용하는 용어‘감미료’단맛을 느끼게 하는 조미료 및 식품첨가물을 의미할 수 있다.The term “sweetener” used in the present specification may mean a seasoning and a food additive that makes a sweet taste.
본 명세서에서 사용하는 용어‘조미료’는 음식을 만드는 주재료인 식품에 첨가해서 음식의 맛을 돋우며 조절하는 물질을 의미할 수 있다.The term “seasoning” used in the present specification may refer to a substance that enhances and regulates the taste of food by adding it to food, which is a main ingredient for making food.
본 발명의 바람직한 양태에 따르면, 본 발명의 상기 지구자는 바람직하게는 헛개나무의 열매일 수 있고, 가장 바람직하게는 발효된 헛개나무 열매일 수 있다.According to a preferred embodiment of the present invention, the above-described earth of the present invention may be preferably fruit of a hut tree, and most preferably fermented hawthorn fruit.
여기서, 발효된 지구자를 사용하면, 발효 지구자의 항산화 효과가 일반적인 지구자의 항산화 효과에 비해 월등하여 다량의 알코올 섭취에 따른 장기 손상을 방지하는 것은 물론, 지구자의 쓴맛을 현저히 감소시켜 숙취해소음료 조성물 또는 숙취해소용 차의 풍미를 비약적으로 증가시킬 수 있기 때문이다. Here, when the fermented earth is used, the antioxidant effect of the fermented earth is superior to that of the normal earth, preventing long-term damage due to intake of a large amount of alcohol, as well as significantly reducing the bitter taste of the earth to reduce the hangover beverage or This is because it can dramatically increase the flavor of a hangover tea.
실제로 발효 지구자를 사용하여 숙취해소음료 조성물을 제조할 경우, 발효되지 않은 지구자를 사용하여 숙취해소음료 조성물을 제조하는 것과 비교하여, 맛은 1.5 배, 혈중 알코올 농도 저해 효과는 1.2 배 증가하는 것을 확인할 수 있었다.In fact, when a hangover-free beverage composition is prepared using a fermented earth, it is confirmed that the taste is 1.5 times higher and the blood alcohol concentration inhibitory effect is increased by 1.2 times compared to a hangover-free beverage composition using an unfermented earth. Could.
상기 발효된 지구자를 제조하는 것은 매우 간단하다. 준비한 지구자를 물에 세척하여 표면에 붙은 흙 따위의 이물질을 제거하고, 분쇄기를 이용하여 분쇄한 이후, 상기 절단한 지구자, 당원 및 유산균 혼합액(수원시 농업기술센터 제공)을 혼합하여 질그릇 입 큰 항아리에 넣고 한지로 봉한 뒤 뚜껑을 덮고, 숙성시켜 제조할 수 있다. It is very simple to prepare the fermented earth. After washing the prepared earthenware with water to remove foreign substances such as dirt attached to the surface, and crushing using a grinder, mix the cut earthenware, sugar, and lactic acid bacteria mixture (provided by the Agricultural Technology Center in Suwon) to open a large bowl Put it in, seal it with Korean paper, cover it with a lid, and mature it.
본 발명의 바람직한 양태에 따르면, 본 발명의 상기 당원은 바람직하게는 설탕, 꿀, 올리고당, 포도당 및 조청을 포함하는 군으로부터 선택될 수 있고, 보다 바람직하게는 꿀 또는 설탕일 수 있으며, 가장 바람직하게는 설탕일 수 있다. 포도당을 이용하여 발효를 진행할 경우 발효는 잘 진행되나, 풍미가 떨어지는 문제가 있고, 꿀을 이용하여 발효를 진행할 경우 완성된 결과물의 풍미는 뛰어나나, 발효가 잘 진행되지 않아, 약효가 떨어지는 문제가 있기 때문이다.According to a preferred embodiment of the present invention, the sugar member of the present invention may be preferably selected from the group comprising sugar, honey, oligosaccharide, glucose and crude, more preferably honey or sugar, most preferably Can be sugar. When fermentation is performed using glucose, fermentation proceeds well, but there is a problem in which flavor is inferior, and when fermentation is performed using honey, the flavor of the finished product is excellent, but fermentation is not progressed well, resulting in a problem of poor efficacy Because there is.
본 발명의 바람직한 양태에 따르면, 본 발명의 상기 당원은 상기 지구자 100 중량부에 대해 바람직하게는 50 중량부 내지 200 중량부를 혼합할 수 있고, 보다 바람직하게는 70 중량부 내지 150 중량부를 혼합할 수 있으며, 가장 바람직하게는 90 중량부 내지 110 중량부를 혼합할 수 있다.According to a preferred embodiment of the present invention, the sugar member of the present invention may preferably mix 50 parts by weight to 200 parts by weight, more preferably 70 parts by weight to 150 parts by weight with respect to 100 parts by weight of the earth It may be, and most preferably, 90 parts by weight to 110 parts by weight may be mixed.
상기 당원을 50 중량부 미만으로 포함시킬 경우 발효가 잘 진행되지 않는 문제가 있고, 200 중량부를 초과하여 포함시킬 경우 완성된 결과물의 당도가 높아지는 문제가 있다.If the sugar content is less than 50 parts by weight, there is a problem that fermentation does not proceed well, and when it is included in excess of 200 parts by weight, the sugar content of the finished product increases.
본 발명의 바람직한 양태에 따르면, 본 발명의 상기 유산균 혼합액은 상기 지구자 100 중량부에 대해 바람직하게는 1 중량부 내지 100 중량부를 첨가할 수 있고, 보다 바람직하게는 5 중량부 내지 50 중량부 첨가할 수 있으며, 가장 바람직하게는 8-15 중량부 첨가할 수 있다.According to a preferred embodiment of the present invention, the lactic acid bacteria mixture solution of the present invention can preferably add 1 part to 100 parts by weight, more preferably 5 parts to 50 parts by weight with respect to 100 parts by weight of the earth It is possible, and most preferably, 8-15 parts by weight can be added.
상기 유산균 혼합액을 1 중량부 미만으로 포함시킬 경우 발효가 잘 진행되지 않는 문제가 있고, 100 중량부를 초과하여 포함시킬 경우 발효 효율이 증가하지 않는 문제가 존재한다.When the lactic acid bacteria mixture is included in less than 1 part by weight, there is a problem that fermentation does not proceed well, and when it is included in excess of 100 parts by weight, there is a problem that fermentation efficiency does not increase.
본 발명의 바람직한 양태에 따르면, 본 발명의 상기 유산균은 바람직하게는 락토바실러스 불가리쿠스(L. bulgarcus), 락토바실러스 애시도필러스(L. acidophilus), 락토바실러스 델브리키(L. delbrichii), 락토바실러스 카제이(L. casei), 락토바실러스 플란타룸(L. plantarum), 락토바실러스 비피더스(L. bifidus), 락토바실러스 김치(L. kimchii), 스트렙토코쿠스 패칼리스(S. faecalis), 스트렙토코쿠스 락티스(S. lactis), 페디오코쿠스 소이아에(P. soyae) 및 페디오코쿠스 펜토사케우스(P. pentosaceus)를 포함하는 군으로부터 선택될 수 있고, 보다 바람직하게는 락토바실러스 김치 또는 락토바실러스 비피더스일 수 있으며, 가장 바람직하게는 락토바실러스 비피더스일 수 있다.According to a preferred embodiment of the present invention, the lactic acid bacteria of the present invention are preferably L. bulgarcus, L. acidophilus, L. acidophilus, L. delbrichii, Lactobacillus casei, L. plantarum, L. bifidus, L. kimchii, S. faecalis, Streptococcus lactis (S. lactis), Pediococcus soiae (P. soyae) and Pediococcus pentosaceus (P. pentosaceus) may be selected from the group comprising, more preferably Lactobacillus It may be kimchi or Lactobacillus bifidus, and most preferably Lactobacillus bifidus.
락토바실러스 비피더스를 이용하여 지구자 발효물을 제조할 경우 다른 유산균주를 사용하는 것에 비해 영양학적으로 우수할 뿐만 아니라, 완성된 조성물의 풍미를 보다 좋게 만들 수 있는 장점이 있다.When using the Lactobacillus bifidus to prepare the fermentation of the earth, it is not only nutritionally superior to using other lactic acid bacteria, but also has the advantage of making the flavor of the finished composition better.
본 발명의 바람직한 양태에 따르면, 상기 발효 시 발효 온도는 바람직하게는 15-40℃일 수 있고, 가장 바람직하게는 20-30℃일 수 있으며, 가장 바람직하게는 22-27℃일 수 있다. 발효 온도가 40℃를 초과할 경우 발효가 급격하게 진행되어, 완성된 조성물에 쓴 맛이 날 수 있는 문제가 있고, 15℃ 미만일 경우 발효가 잘 진행되지 않는 문제가 존재할 수 있다.According to a preferred embodiment of the present invention, the fermentation temperature during fermentation may be preferably 15-40 ° C, most preferably 20-30 ° C, and most preferably 22-27 ° C. When the fermentation temperature exceeds 40 ° C, fermentation proceeds rapidly, and there is a problem that a bitter taste may occur in the finished composition, and when it is less than 15 ° C, there may be a problem that fermentation does not proceed well.
본 발명의 바람직한 양태에 따르면, 상기 발효 시 발효 기간은 바람직하게는 7일 내지 12 개월일 수 있고, 보다 바람직하게는 1-6 개월일 수 있으며, 가장 바람직하게는 2-3개월일 수 있다. 발효 기간이 12 개월을 초과할 경우 완성된 조성물의 색도가 좋지 않고, 완성된 조성물에 쓴 맛이 날 수 있는 문제가 있고, 발효 기간이 7일 미만일 경우 발효가 잘 진행되지 않는 문제가 존재한다.According to a preferred embodiment of the present invention, the fermentation period during the fermentation may be preferably 7 days to 12 months, more preferably 1-6 months, and most preferably 2-3 months. When the fermentation period exceeds 12 months, the chromaticity of the finished composition is not good, there is a problem that the bitter taste may occur in the finished composition, and when the fermentation period is less than 7 days, there is a problem that fermentation does not proceed well.
본 명세서에서 혼합 약재 추출물을 언급하면서 사용되는 용어 “추출물”은 상기 언급한 혼합 약재의 잎 및/또는 줄기에 추출용매를 처리하여 얻은 추출 결과물뿐만 아니라 상기 혼합 약재의 잎 및/또는 줄기 자체를 섭취할 수 있도록 제형화(예컨대, 분말화)된 가공물도 포함하는 의미를 갖는다.The term “extract” used while referring to the extract of a mixed medicinal material in this specification ingests the leaf and / or stem of the mixed medicinal material as well as the extraction result obtained by treating the leaf and / or stem of the above-mentioned mixed medicinal material with an extractant. It has the meaning of including a processed product (eg, powdered) so as to be able to do so.
만일, 본 발명의 조성물에서 이용되는 추출물을 상기 혼합 약재의 잎 및/또는 줄기에 추출용매를 처리하여 얻는 경우에는, 다양한 추출용매가 이용될 수 있다. 바람직하게는, (a) 물, (b) 탄소수 1-4의 무수 또는 함수 저급 알코올 (예: 메탄올, 에탄올, 프로판올, 부탄올, 노말-프로판올, 이소-프로판올 및 노말-부탄올 등), (c) 상기 저급 알코올과 물과의 혼합용매, (d) 아세톤, (e) 에틸 아세테이트, (f) 클로로포름, (g) 1,3-부틸렌글리콜, (h) 헥산, (i) 디에틸에테르, 또는 (j) 부틸아세테이트를 식물에 처리하여 추출물을 얻을 수 있다. If, when the extract used in the composition of the present invention is obtained by treating an extractant on the leaves and / or stems of the mixture, various extractants may be used. Preferably, (a) water, (b) anhydrous or hydrous lower alcohols having 1 to 4 carbon atoms (e.g. methanol, ethanol, propanol, butanol, normal-propanol, iso-propanol and normal-butanol, etc.), (c) A mixed solvent of the lower alcohol and water, (d) acetone, (e) ethyl acetate, (f) chloroform, (g) 1,3-butylene glycol, (h) hexane, (i) diethyl ether, or (j) Butyl acetate can be treated on plants to obtain extracts.
본 명세서에서 사용되는 용어 “추출물”은 상술한 바와 같이 당업계에서 조추출물(crude extract)로 통용되는 의미를 갖지만, 광의적으로는 추출물을 추가적으로 분획(fractionation)한 분획물도 포함한다. 즉, 혼합 약재의 잎 및/또는 줄기 추출물은 상술한 추출용매를 이용하여 얻은 것뿐만 아니라, 여기에 정제과정을 추가적으로 적용하여 얻은 것도 포함한다. 예컨대, 상기 추출물을 일정한 분자량 컷-오프 값을 갖는 한외 여과막을 통과시켜 얻은 분획, 다양한 크로마토그래피(크기, 전하, 소수성 또는 친화성에 따른 분리를 위해 제작된 것)에 의한 분리 등, 추가적으로 실시된 다양한 정제 방법을 통해 얻어진 분획도 본 발명의 혼합 약재의 잎 및/또는 줄기 추출물에 포함되는 것이다.As used herein, the term “extract” has a meaning commonly used as a crude extract in the art as described above, but broadly also includes a fraction in which an extract is additionally fractionated. That is, the leaf and / or stem extract of the mixed medicinal material includes not only those obtained using the above-described extraction solvent, but also those obtained by additionally applying a purification process. For example, a fraction obtained by passing the extract through an ultrafiltration membrane having a constant molecular weight cut-off value, separation by various chromatography (made for separation according to size, charge, hydrophobicity or affinity), etc. Fractions obtained through the purification method are also included in the leaf and / or stem extract of the mixed medicine of the present invention.
본 발명에서 이용되는 혼합 약재의 잎 및/또는 줄기 추출물은 감압 증류 및 동결 건조 또는 분무 건조 등과 같은 추가적인 과정에 의해 분말 상태로 제조될 수 있다.The leaf and / or stem extract of the mixed medicinal material used in the present invention may be prepared in powder form by additional processes such as distillation under reduced pressure and freeze drying or spray drying.
본 발명의 바람직한 양태에 따르면, 본 발명의 상기 감미료는 액상과당 및 스테비오사이드일 수 있고, 상기 액상과당은 숙취해소음료 조성물 총 중량을 기준으로 바람직하게는 5-20 중량% 포함할 수 있고, 가장 바람직하게는 9-12 중량% 포함할 수 있다.According to a preferred embodiment of the present invention, the sweetener of the present invention may be liquid fructose and stevioside, and the liquid fructose may preferably contain 5-20% by weight, based on the total weight of the hangover anti-drink composition, most Preferably it may contain 9-12% by weight.
상기 액상과당을 5 중량% 미만으로 포함할 경우 음용자에게 숙취해소음료 조성물의 쓴맛이 강하게 느껴질 수 있고, 20 중량%를 초과하여 포함할 경우 단맛이 너무 강하게 나는 문제가 존재한다.When the liquid fructose is contained in an amount of less than 5% by weight, the bitter taste of the beverage composition may be felt by hangover to the drinker, and when it exceeds 20% by weight, the sweetness is too strong.
본 발명의 바람직한 양태에 따르면, 본 발명의 상기 소화제 조성물은 바람직하게는 창출 열수 추출물 및 진피 열수 추출물의 혼합물일 수 있다.According to a preferred embodiment of the present invention, the extinguishing agent composition of the present invention may preferably be a mixture of hot water extract and dermal hot water extract.
본 발명의 바람직한 양태에 따르면, 본 발명의 상기 단백질분해효소 조성물은 바람직하게는 갈화 열수 추출물 및 감초 열수 추출물의 혼합물일 수 있다.According to a preferred embodiment of the present invention, the protease composition of the present invention may preferably be a mixture of hot water extract and licorice hot water extract.
본 발명의 바람직한 양태에 따르면, 본 발명의 상기 비타민은 바람직하게는 비타민B12일 수 있다.According to a preferred embodiment of the present invention, the vitamin of the present invention may be preferably vitamin B12.
본 발명의 바람직한 양태에 따르면, 본 발명의 상기 조성물은 바람직하게는 5-10 중량%의 포도당을 추가적으로 포함할 수 있다.According to a preferred embodiment of the present invention, the composition of the present invention may additionally preferably contain 5-10% by weight of glucose.
본 발명의 바람직한 양태에 따르면, 본 발명의 상기 감미료 및 조미료는 바람직하게는 액상과당, 구연산, 비타민C, 스테비오사이드 및 합성착향료를 포함하는 군으로부터 선택될 수 있다.According to a preferred embodiment of the present invention, the sweetener and seasoning of the present invention may preferably be selected from the group comprising liquid fructose, citric acid, vitamin C, stevioside, and synthetic flavoring agents.
본 발명의 특징 및 이점을 요약하면 다음과 같다: The features and advantages of the present invention are summarized as follows:
(ⅰ) 본 발명은 다음을 포함하는 지구자를 포함하는 숙취해소용음료 조성물을 제공한다: (a) 상기 조성물 총 중량을 기준으로 지구자 추출물, 상기 지구자 추출물 100 중량부를 기준으로 50 중량부 내지 100 중량부의 소화제 조성물, 20 중량부 내지 30 중량부의 단백질분해효소 조성물 및 1 중량부 내지 5 중량부의 비타민을 포함하는 혼합물 5-20 중량%; (b) 감미료(甘味料) 및 조미료(調味料) 5-20 중량%; 및 (c) 잔량의 정제수.(Ⅰ) The present invention provides a beverage composition for hangover relief comprising a terrestrial comprising: (a) a terrestrial extract based on the total weight of the composition, 50 parts by weight based on 100 parts by weight of the terrestrial extract 5-20% by weight of a mixture comprising 100 parts by weight of an extinguishing agent composition, 20 parts by weight to 30 parts by weight of a protease composition and 1 part by weight to 5 parts by weight of vitamin; (b) 5-20% by weight of sweeteners and seasonings; And (c) a residual amount of purified water.
(ⅱ) 본 발명의 숙취해소음료 조성물은 기존의 숙취해소음료 조성물과 비교하여 기호성이 탁월하고, 숙취해소 효과가 현저하며, 저렴한 가격에 숙취해소음료를 제조할 수 있는 장점이 존재한다.(Ii) The hangover-removing beverage composition of the present invention has advantages of excellent palatability, outstanding hangover-relieving effect, and the advantage of being able to manufacture a hangover-reducing beverage at an inexpensive price compared to the existing hangover-reducing beverage composition.
이하, 실시예를 통하여 본 발명을 더욱 상세히 설명 하고자 한다. 이들 실시예는 오로지 본 발명을 보다 구체적으로 설명하기 위한 것으로서, 본 발명의 요지 따라 본 발명의 범위가 이들 실시예에 의해 제한되지 않는다는 것은 본 발명이 속하는 기술 분야에서 통상의 지식을 가진 자에게 있어서 자명할 것이다. Hereinafter, the present invention will be described in more detail through examples. These examples are only intended to explain the present invention in more detail, and according to the gist of the present invention, the scope of the present invention is not limited by these examples to those skilled in the art to which the present invention pertains. It will be self-evident.
실시예Example
본 명세서 전체에 걸쳐, 특정 물질의 농도를 나타내기 위하여 사용되는 “%“는 별도의 언급이 없는 경우, 고체/고체는 (중량/중량) %, 고체/액체는 (중량/부피) %, 그리고 액체/액체는 (부피/부피) %이다.Throughout this specification, “%” used to indicate the concentration of a specific substance, unless otherwise specified, is solids / solids (weight / weight)%, solids / liquids (weight / volume)%, and The liquid / liquid is (volume / volume)%.
제조예Manufacturing example
제조예 1 : 약재 추출물의 제조Preparation Example 1: Preparation of herbal extracts
우선, 지구자, 창출, 진피, 갈화 및 감초 시료를 각각 1.0 kg 준비하였다. 상기 시료들 각각 중량대비 5배의 정제수에 넣고 105℃에서 5시간 가온 추출하였다. 추출공정이 종료되면 거름종이(Whatman paper No. 1)로 거르고, 0.45 ㎛의 멤브레인 필터(TF-450, 60173, PALL Life Sciences)로 재여과한 후 다음으로 물을 제거하기 위해 우선 회전 진공 증발기(Rotary vacuum evaporator)로 농축하고 이어서 동결 건조하는 방법을 사용하였다. 이로써 지구자 추출물 80.21 g, 창출 추출물 90.14 g, 진피 추출물 72.17 g, 갈화 추출물 69.82 g 및 감초 추출물 100.92 g을 수득하였다.First of all, 1.0 kg of sample of earth, creation, dermis, browning and licorice were prepared. Each of the samples was placed in purified water 5 times by weight and extracted with heating at 105 ° C for 5 hours. After the extraction process is finished, filter with filter paper (Whatman paper No. 1), re-filter with a 0.45 µm membrane filter (TF-450, 60173, PALL Life Sciences), and then first rotate a vacuum evaporator to remove water ( Rotary vacuum evaporator) and then freeze-dried. As a result, 80.21 g of ginseng extract, 90.14 g of generated extract, 72.17 g of dermis extract, 69.82 g of gallium extract and 100.92 g of licorice extract were obtained.
제조예 2 : 혼합 약재 추출물을 포함하는 한방차 제조Preparation Example 2: Preparation of herbal tea containing mixed herbal extracts
숙취해소에 탁월한 효과가 있고, 저렴한 가격에 제조가 가능하며, 음용 시 거부감 없는 풍미를 나타내는 숙취해소음료를 제조하기 위해 베이스 원료로 상술한 지구자 열수 추출물을 혼합 약재 추출물 중량기준 50% 사용하였다. 지구자는 비교적 저렴한 가격에 입수할 수 있고, 탁월한 숙취해소 및 해갈 효과가 있을 뿐만 아니라, 맛이 좋아 한국인의 입맛에 잘 맞는 숙취해소음료의 제조가 가능하여 이를 베이스 원료로 사용하였다. 상기 지구자 추출물을 베이스 원료로 창출, 진피, 갈화, 감초 추출물를 포함하는 군으로부터 선택된 최소 1종 이상의 추출물을 추가적으로 포함시켜 혼합 약재 추출물을 포함하는 한방차 조성물을 제조하는 실험을 150 회 이상 반복하였다. 맛 및 향을 기준으로, 현저히 쓰거나, 불쾌한 풍미를 나타내는 한방차 조성물은 혼합 약재 추출물 후보군에서 제외하였고, 직관적으로 우수한 풍미를 나타내는 한방차 조성물 5개를 선별하였으며, 구체적인 혼합 약재 추출물의 조성비는 하기 표 1과 같다. 한편, 상기 혼합 약재 추출물을 포함하는 한방차 조성물은 상기 혼합 약재 추출물 및 꿀을 중량기준 1 : 1 내지 2의 비율로 혼합한 이후 끓는 물을 적량 첨가한 후 교반하여 제조하였다.The above-mentioned geothermal hot water extract was used as a base raw material in an amount of 50% by weight of the mixed medicinal herb extract to produce a hangover-reducing beverage that has an excellent effect on relieving a hangover, can be manufactured at an inexpensive price, and exhibits a flavor without rejection when drinking. The earthworm can be obtained at a relatively low price, and has an excellent hangover and hazel effect, and has a good taste, so it is possible to manufacture a hangover and drink that suits the taste of Koreans. The experiment for preparing the herbal tea composition containing the mixed herbal extract was repeated more than 150 times by additionally including at least one or more extracts selected from the group containing the extract of the earthenella as a base raw material, dermis, browning, and licorice extract. Based on taste and aroma, the herbal tea composition exhibiting a remarkably bitter or unpleasant flavor was excluded from the candidate group for mixed herbal extracts, and five herbal tea compositions showing intuitively superior flavor were selected, and the composition ratio of specific herbal extracts is shown in the table below. Same as 1. On the other hand, the herbal tea composition containing the mixed herbal extract was prepared by mixing the mixed herbal extract and honey in a ratio of 1: 1 to 2 by weight and then adding appropriate amounts of boiling water and stirring.
제조예 3 : 혼합 약재 추출물을 포함하는 숙취해소음료 조성물의 제조Preparation Example 3: Preparation of a hangover-free beverage composition comprising a mixed herbal extract
하기 표 2의 조성(중량기준)으로 상기 표 1에서 제조한 실시예 1 내지 실시예 5의 혼합 약재 추출물, 포도당, 구연산(결정), 비타민B12, 스테비오사이드, 허브향(합성착향료) 및 정제수를 혼합하여 하기 실시예 6 내지 실시예 10의 혼합 약재 추출물을 포함하는 숙취해소음료 조성물을 제조하였다.To the composition (by weight) of Table 2, the mixed herbal extracts of Examples 1 to 5 prepared in Table 1, glucose, citric acid (crystal), vitamin B12, stevioside, herbal flavor (synthetic fragrance) and purified water By mixing to prepare a hangover-drinking beverage composition comprising the mixed herbal extracts of Examples 6 to 10 below.
실험예Experimental example
실험예 1 : 관능평가Experimental Example 1: Sensory evaluation
실험예 1-1 : 혼합 약재 추출물을 포함하는 한방차의 관능평가Experimental Example 1-1: Sensory evaluation of herbal tea containing mixed herbal extracts
기호 평가에서는 상기 실시예 1 내지 실시예 5의 방법으로 제조한 혼합 약재 추출물을 포함하는 한방차의 풍미와 후각적 기호를 조사하였으며, 30명을 선정하여 해당 인원을 대상으로 하여 실시하였다. 상기 실시예 1 내지 실시예 5의 방법으로 제조한 혼합 약재 추출물을 포함하는 한방차를 그 대상으로 하여, 시식 후 1에서 10까지 10단계로 제조방법 별 처리구의 기호성을 평가하여 기록하게 하였다. 시식 시에는 상기 실시예 1 내지 실시예 5의 방법으로 제조한 혼합 약재 추출물을 포함하는 한방차 100 mL를 제공하였다. 기호성은 풍미와 후각적 특성 두 가지 요소로 분리하여 시식 및 기록하였다. 비교예로는 칡뿌리 추출물만을 포함하는 한방차 100 mL를 사용하였다.In the evaluation of the taste, the flavor and olfactory taste of the herbal tea containing the mixed herbal extracts prepared by the methods of Examples 1 to 5 were investigated, and 30 persons were selected and conducted for the relevant personnel. The herbal tea containing the mixed herbal extracts prepared by the methods of Examples 1 to 5 was targeted, and the tasteability of each treatment method was evaluated and recorded in 10 steps from 1 to 10 after tasting. At the time of tasting, 100 mL of herbal teas containing the mixed herbal extracts prepared by the methods of Examples 1 to 5 were provided. The palatability was divided into two factors, flavor and olfactory properties, and sampled and recorded. As a comparative example, 100 mL of herbal tea containing only the root extract was used.
실험 결과, 상기 실시예 1 내지 실시예 5의 방법으로 제조한 혼합 약재 추출물을 포함하는 한방차의 기호도는 하기 표 3과 같다. As a result of the experiment, the preferences of the herbal tea containing the mixed herbal extracts prepared by the methods of Examples 1 to 5 are shown in Table 3 below.
정리하자면 본 발명의 실시예 1, 실시예 3, 실시예 2, 실시예 4, 실시예 5 및 비교예의 방법으로 제조한 혼합 약재 추출물을 포함하는 한방차 순으로 풍미가 높게 평가되었으며, 후각적 기호성 측면에서도 상기 풍미 기호성 평가와 동일한 결과가 나왔다. 즉 두 측면의 답변 모두에서 실시예 1에 해당하는 시료가 가장 높은 선호도를 얻어냈으며, 그 수치에 있어서도 비교예와 비교하여 의미 있는 수준의 유의확률을 보였다. 이는 본 발명에서 제시하는 방식과 비율의 제조 방법이 기타 제조 방법에 비하여 뛰어난 효과를 가지고 있음을 입증한다. In summary, the flavors of the present invention were evaluated in the order of herbal tea containing mixed herbal extracts prepared by the methods of Example 1, Example 3, Example 2, Example 4, Example 5 and Comparative Example, and olfactory palatability. In terms of the results, the same results as those of the palatability evaluation were obtained. That is, in both answers, the sample corresponding to Example 1 obtained the highest preference, and the numerical value showed a significant level of probability compared to the comparative example. This proves that the method of manufacturing the method and ratio suggested in the present invention has an excellent effect compared to other manufacturing methods.
위 결과를 바탕으로 판단하였을 때 본 발명에서 제시하는 제조 방법으로 제조한 한방차의 풍미 및 후각적 기호성이 다른 제조 방법에 의한 것에 비하여 월등히 향상되었음을 확인할 수 있었다. Judging from the above results, it was confirmed that the flavor and olfactory palatability of the herbal tea produced by the manufacturing method proposed in the present invention were significantly improved compared to that of other manufacturing methods.
각 항목별 상단칸은 평균값, 하단칸은 그 표준편차The upper column for each item is the average value, and the lower column is the standard deviation.
실험에 1-2 : 혼합 약재 추출물을 포함하는 숙취해소음료 조성물의 관능평가Experiment 1-2: Sensory evaluation of hangover-free beverage composition containing mixed herbal extracts
기호 평가에서는 상기 실시예 6 내지 실시예 10의 방법으로 제조한 숙취해소음료 조성물의 풍미와 후각적 기호를 조사하였으며, 30명을 선정하여 해당 인원을 대상으로 하여 실시하였다. 상기 실시예 6 내지 실시예 10의 방법으로 제조한 숙취해소음료 조성물을 그 대상으로 하여, 시식 후 1에서 10까지 10단계로 제조방법 별 처리구의 기호성을 평가하여 기록하게 하였다. 시식 시에는 상기 실시예 6 내지 실시예 10의 방법으로 제조한 숙취해소음료 조성물 100 mL를 제공하였다. 기호성은 풍미와 후각적 특성 두 가지 요소로 분리하여 시식 및 기록하였다. 비교예로는 약채 추출물로 지구자 추출물만을 포함하는 것을 제외하고는 상기 실시예 6 내지 실시예 10의 방법으로 제조한 숙취해소음료 조성물과 동일한 방법으로 제조한 숙취해소음료 조성물 100 mL를 사용하였다.In the evaluation of the taste, the flavor and olfactory taste of the hangover-reducing beverage composition prepared by the methods of Examples 6 to 10 were investigated, and 30 persons were selected for the relevant personnel. The hangover-reducing beverage compositions prepared by the methods of Examples 6 to 10 were targeted, and after tasting, the tasteability of each treatment method was evaluated and recorded in 10 steps from 1 to 10. At the time of tasting, 100 mL of a hangover-free beverage composition prepared by the method of Examples 6 to 10 was provided. The palatability was divided into two factors, flavor and olfactory properties, and sampled and recorded. As a comparative example, 100 mL of a hangover-relieving beverage composition prepared in the same manner as the hangover-relieving beverage composition prepared by the method of Examples 6 to 10 was used, except that only the extract of the herb was included as the herbal extract.
실험 결과, 상기 실시예 6 내지 실시예 10의 방법으로 제조한 숙취해소음료 조성물의 기호도는 하기 표 4와 같다. As a result of the experiment, the preferences of the hangover cancellation beverage compositions prepared by the methods of Examples 6 to 10 are shown in Table 4 below.
정리하자면 본 발명의 실시예 6, 실시예 8, 실시예 7, 실시예 9, 실시예 10 및 비교예의 방법으로 제조한 숙취해소음료 조성물 순으로 풍미가 높게 평가되었으며, 후각적 기호성 측면에서도 상기 풍미 기호성 평가와 동일한 결과가 나왔다. 즉 두 측면의 답변 모두에서 실시예 6에 해당하는 시료가 가장 높은 선호도를 얻어냈으며, 그 수치에 있어서도 비교예와 비교하여 의미 있는 수준의 유의확률을 보였다. 이는 본 발명에서 제시하는 방식과 비율의 제조 방법이 기타 제조 방법에 비하여 뛰어난 효과를 가지고 있음을 입증한다. In summary, the flavor was evaluated in the order of the hangover anti-drink composition prepared by the method of Example 6, Example 8, Example 7, Example 9, Example 10 and Comparative Example of the present invention, and the flavor was also observed in terms of olfactory palatability. The same result was obtained with palatability evaluation. That is, in both answers, the sample corresponding to Example 6 obtained the highest preference, and the numerical value showed a significant probability of significance compared to the comparative example. This proves that the method of manufacturing the method and ratio suggested in the present invention has an excellent effect compared to other manufacturing methods.
위 결과를 바탕으로 판단하였을 때 본 발명에서 제시하는 제조 방법으로 제조한 한방차의 풍미 및 후각적 기호성이 다른 제조 방법에 의한 것에 비하여 월등히 향상되었음을 확인할 수 있었다. Judging from the above results, it was confirmed that the flavor and olfactory palatability of the herbal tea produced by the manufacturing method proposed in the present invention were significantly improved compared to that of other manufacturing methods.
각 항목별 상단칸은 평균값, 하단칸은 그 표준편차The upper column for each item is the average value, and the lower column is the standard deviation.
실험예 2 : 혈중 알코올 농도 평가Experimental Example 2: Blood alcohol concentration evaluation
실험예 2-1 : 동물실험Experimental Example 2-1: Animal Experiment
본 발명에 따른 상기 실시예 6의 숙취해소용음료 조성물의 알코올 분해 정도를 측정하기 위해 쥐를 이용한 혈중 알코올 농도의 감소 속도를 측정하였다. 이를 위하여 체중 200-250 g의 Sparague-Dawlay(SD)계 수컷 흰쥐 10마리를 5마리씩 두 군으로 나누고 각각 1일간 절식 후 실험 개시 30분전에 하나의 군에는 상기 실시예 6의 숙취해소용음료 조성물 100 mg/kg 생수에 현탁시켜 쥐들에 경구 투여하고, 다른 군에는 생수만을 동일한 양 투여하였다. 30분 후에 순수 에탄올을 증류수에 40 ㎎/ml 의 농도로 희석시켜 1 g/kg의 농도로 각군의 실험쥐들에게 경구 투여하였다. 이와 같이 알코올을 투여한 쥐들을 2시간 후에 폐로부터 0.7 ml의 혈액을 채취한 후 4℃에서 5000 rpm으로 10 분간 원심 분리하여 혈청을 분리하였다. 분리된 혈장액을 디지털 에탄올 농도계(Atago PET-109, Japan)를 이용해 혈액 내 알코올 농도를 측정하였으며, 그 결과를 하기 표 5에 나타내었다. 하기 표 5에서 확인할 수 있는 바와 같이 상기 실시예 6의 숙취해소용음료 조성물을 투여한 쥐들의 경우 알코올 농도가 현저하게 떨어짐을 확인할 수 있었다.In order to measure the degree of alcohol decomposition of the beverage composition for relieving hangover of Example 6 according to the present invention, the rate of decrease in the concentration of alcohol in the blood using rats was measured. To this end, 10 male rats of Sparague-Dawlay (SD) based body weight of 200-250 g were divided into two groups of five, each fasted for 1 day, and 30 minutes before the start of the experiment, one group had a hangover relieving beverage composition of Example 6 above. It was suspended in 100 mg / kg bottled water and administered orally to mice, and the other group was administered the same amount of bottled water only. After 30 minutes, pure ethanol was diluted in distilled water to a concentration of 40 mg / ml and orally administered to each group of mice at a concentration of 1 g / kg. As described above, 0.7 ml of blood was collected from the lungs after 2 hours of alcohol-administered rats and centrifuged at 5000 rpm for 10 minutes at 4 ° C to separate serum. The separated plasma was measured for alcohol concentration in blood using a digital ethanol concentration meter (Atago PET-109, Japan), and the results are shown in Table 5 below. As can be seen in Table 5 below, it was confirmed that the alcohol concentration of the mice to which the beverage composition for hangover relieving of Example 6 was administered was significantly lowered.
실험예 2-2 : 임상실험Experimental Example 2-2: Clinical Trial
개인에 따라 알콜 분해 능력이 다른 점을 감안하여, 개인별로 일주일 간격으로 각 알코올과 함께 각 조성물을 섭취하고 음주측정을 하는 방법으로 실험을 실시하였다. 30대 중반에서 40대 초반의 중년 남성 10명을 대상으로 하였으며, 이들의 평균 음주회수는 1주일 2회, 평균음주량은 소주(1병 360 mL) 2병이었다. 실험은 매주 수요일 실시하였으며 실험 전 2일(월, 화)간은 금주하도록 하였다. 기본 시료(대조구)로는 소주(360 ml, 19.5%)1병과 두부 154 g, 오이25 g, 김치 40 g을 30분에 걸쳐 섭취하도록 하였으며, 시식이 완료된 시점부터 음주측정기(센텍코리아, AL1102)를 사용하여 30분 간격으로 혈중 알코올 농도(%BAC)를 측정하고 그 결과를 하기 표 6에 나타냈다. 상기 실시예 6의 숙취해소용음료 조성물 100 mL는 상기 기본 시료의 섭취를 시작한 후 10분 후에 음용하였으며, 시료 이외의 음식이나 음료는 금지하고 음주 측정동안 행동도 자제하도록 하였다. 비교예로는 시판 숙취해소음료인 컨*션 100 mL를 음용시킨 후 음주측정을 실시하였다.Considering that the ability to decompose alcohol differs depending on the individual, the experiment was conducted by ingesting each composition with each alcohol at a weekly interval for each individual and measuring alcohol consumption. Ten middle-aged males in their mid 30s to early 40s were enrolled, and their average alcohol intake was twice a week, and the average alcoholic beverage was 2 bottles of soju (1 bottle 360 mL). The experiment was conducted every Wednesday, and it was to be absent for two days before the experiment (Mon, Tue). As a basic sample (control), a bottle of soju (360 ml, 19.5%) and 154 g of tofu, 25 g of cucumber, and 40 g of kimchi were ingested over 30 minutes. Blood alcohol concentration (% BAC) at 30-minute intervals was measured and the results are shown in Table 6 below. 100 mL of the hangover-releasing beverage composition of Example 6 was ingested 10 minutes after the intake of the basic sample was started, and food or beverages other than the sample were prohibited and action was also restrained during drinking measurement. As a comparative example, after drinking 100 mL of a commercial hangover-reducing beverage, a drinking test was performed.
상기 표 6에서 확인할 수 있는 바와 같이 상기 실시예 6의 숙취해소용음료 조성물은 초기 알코올 분해능력 뿐만 아니라, 지속적인 알코올 분해능력 또한 대조구 및 비교예와 비교하여 우수함을 알 수 있었다.As can be seen from Table 6, it was found that the beverage composition for releasing hangovers of Example 6 was superior to the initial alcohol decomposition ability as well as the continuous alcohol decomposition ability compared to the control and comparative examples.
Claims (8)
(a) 상기 조성물 총 중량을 기준으로 지구자 추출물, 상기 지구자 추출물 100 중량부를 기준으로 50 중량부 내지 100 중량부의 소화제 조성물, 20 중량부 내지 30 중량부의 단백질분해효소 조성물 및 1 중량부 내지 5 중량부의 비타민을 포함하는 혼합물 5-20 중량%;
(b) 감미료(甘味料) 및 조미료(調味料) 5-20 중량%; 및
(c) 잔량의 정제수.
Beverage composition for hangover remedies, including earthworms, including:
(a) Based on the total weight of the composition, the terrestrial extract, 50 parts by weight to 100 parts by weight of the digestive agent composition, 20 parts by weight to 30 parts by weight of the protease composition and 1 part by weight to 5 parts by weight of the earth extract 5-20% by weight of a mixture comprising parts by weight of vitamins;
(b) 5-20% by weight of sweeteners and seasonings; And
(c) Remaining purified water.
상기 추출물의 추출용매는 물, 에탄올, 메탄올, 메틸렌클로라이드, 에틸아세테이트, 부탄올, 헥산, 부틸렌글리콜, 클로로포름 및 이들의 혼합물을 포함하는 군으로부터 선택된 것을 특징으로 하는 조성물.
According to claim 1,
The extraction solvent of the extract is water, ethanol, methanol, methylene chloride, ethyl acetate, butanol, hexane, butylene glycol, chloroform, and a composition selected from the group comprising a mixture thereof.
상기 추출물의 추출용매는 물인 것을 특징으로 하는 조성물.
According to claim 2,
The extraction solvent of the extract is characterized in that the water composition.
상기 소화제 조성물은 창출 열수 추출물 및 진피 열수 추출물의 혼합물인 것을 특징으로 하는 조성물.
According to claim 1,
The extinguishing agent composition is a composition characterized in that the mixture of the generated hot water extract and dermal hot water extract.
상기 단백질분해효소 조성물은 갈화 열수 추출물 및 감초 열수 추출물의 혼합물인 것을 특징으로 하는 조성물.
According to claim 1,
The protease composition is a composition characterized in that the mixture of hot water extract and licorice hot water extract.
상기 비타민은 비타민B12인 것을 특징으로 하는 조성물.
According to claim 1,
The vitamin is a composition characterized in that vitamin B12.
상기 조성물은 5-10 중량%의 포도당을 추가적으로 포함하는 것을 특징으로 하는 조성물.
According to claim 1,
The composition is characterized in that it further comprises 5-10% by weight of glucose.
상기 감미료 및 조미료는 액상과당, 구연산, 비타민C, 스테비오사이드 및 합성착향료를 포함하는 군으로부터 선택되는 것을 특징으로 하는 조성물.
According to claim 1,
The sweetener and seasoning is a composition characterized in that it is selected from the group comprising liquid fructose, citric acid, vitamin C, stevioside and synthetic flavoring agents.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020180114745A KR20200035569A (en) | 2018-09-27 | 2018-09-27 | Beverage Composition Comprising Hovenia dulcis Thunberg Fruit for Treating Hangover |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020180114745A KR20200035569A (en) | 2018-09-27 | 2018-09-27 | Beverage Composition Comprising Hovenia dulcis Thunberg Fruit for Treating Hangover |
Publications (1)
Publication Number | Publication Date |
---|---|
KR20200035569A true KR20200035569A (en) | 2020-04-06 |
Family
ID=70282191
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020180114745A KR20200035569A (en) | 2018-09-27 | 2018-09-27 | Beverage Composition Comprising Hovenia dulcis Thunberg Fruit for Treating Hangover |
Country Status (1)
Country | Link |
---|---|
KR (1) | KR20200035569A (en) |
-
2018
- 2018-09-27 KR KR1020180114745A patent/KR20200035569A/en unknown
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TWI500391B (en) | Composition for reliving and preventing hangover and beverage comprising composition | |
JP4589212B2 (en) | Proanthocyanidin-containing food and process for producing the same | |
KR101301094B1 (en) | Composition for relieving hangover or improving liver function | |
KR101687982B1 (en) | Composition for improving sexual functionality having effects of increasing of the number of sperm and protection of environmental hormone and manufacturing method thereof | |
KR101784870B1 (en) | A beverage composition for relieving hangover and thereof manufacturing method | |
KR101324431B1 (en) | Composition effective for removing hangover | |
KR101588378B1 (en) | Method for manufacturing hangover curing agent and hangover curing agent manufactured by the same | |
KR101461165B1 (en) | Hangover curing agent | |
KR101524373B1 (en) | Beverage Composition for Treating Hangover | |
CN107557254B (en) | Litchi rose wine, preparation method and application of litchi rose wine in qi and blood tonifying and oxidation resistance | |
KR20200062856A (en) | Chocolate Comprising Hovenia dulcis Thunberg Fruit for Treating Hangover | |
KR20180019845A (en) | Composition for Treating Hangover Comprising Extract of Protaetia Orientalis Larva and Hovenia Dulcis Fruit | |
JP2007518418A (en) | Natural tea effective in eliminating drunkenness and restoring liver function and method for producing the same | |
CN105613848A (en) | Sober-up liver-protection health-care tea and preparation method thereof | |
KR100638491B1 (en) | Compounds for relief of alcoholic hangover and drug containing the compounds | |
KR20200035569A (en) | Beverage Composition Comprising Hovenia dulcis Thunberg Fruit for Treating Hangover | |
KR20200062879A (en) | Candy Comprising Hovenia dulcis Thunberg Fruit for Treating Hangover | |
JPH08317781A (en) | Black tea-blended beet tea beverage and its production | |
KR20200121000A (en) | Flavor Improvement Method for Composition for Preventing Alcoholic Dementia | |
KR20200120997A (en) | Chocolate Chip for Preventing Alcoholic Dementia | |
KR20200120856A (en) | Ice Cream for Preventing Alcoholic Dementia | |
KR20200120998A (en) | Syrup Composition for Preventing Alcoholic Dementia | |
KR20200120999A (en) | Syrup Composition for Preventing Alcoholic Dementia | |
CN107279643A (en) | One kind tree grape sugar-free beverage and preparation method thereof | |
KR20210023085A (en) | Concentrate Composition for Preventing Alcoholic Dementia |