KR20200020114A - Cosmetic Composition for Skin Temperature Sensitive Adhesive Sheet and Adhesive Sheet Using the Same - Google Patents

Abstract

The present invention relates to a cosmetic composition for a skin temperature-sensitive adhesive sheet, comprising a cosmetic component, and an adhesive component comprising a curing agent, an organic solvent, and a resin consisting of 50 to 90 wt% of an acrylic monomer having a glass transition temperature of 30 to 40°C, and 10 to 50 wt% of a vinyl acetate monomer; and to an adhesive sheet using the cosmetic composition. The present invention relates to a cosmetic composition comprising a biomedical polymer whose viscosity changes around 30°C, which is the temperature of the skin, to improve adhesion to the skin, and having reduced skin irritation and a percutaneous absorption effect of cosmetic ingredients; and to an adhesive sheet using the cosmetic composition.

Description

Cosmetic composition for temperature sensitive adhesive sheet and adhesive sheet using same. {Cosmetic Composition for Skin Temperature Sensitive Adhesive Sheet and Adhesive Sheet Using the Same}

The present invention relates to a cosmetic composition for a temperature-sensitive adhesive sheet and an adhesive sheet using the same, more specifically, the viscosity changes within about 30 ℃ of the temperature of the skin to improve the adhesion to the skin, the percutaneous absorption effect of the cosmetic component And it relates to a cosmetic composition comprising a biomedical polymer for a temperature-sensitive adhesive sheet with reduced skin irritation and an adhesive sheet using the same.

In general, the pressure-sensitive adhesive composition adhering to the skin often leaks from a nonwoven fabric, which is a support, or the pressure-sensitive adhesive component remains on the skin, thereby causing discomfort to the user. In addition, if the curing of the pressure-sensitive adhesive layer proceeds too much, there is a problem in that the adhesiveness is degraded and the skin damage when leaving the skin or the transdermal absorption performance of the active ingredient deteriorates. Therefore, it is important to optimize the composition and composition of the adhesive for applying to the skin.

In view of these problems, Korean Patent Publication No. 10-0903783 uses an acrylate polymer having a low content of β-hydroxypropionic acid (salt) to stabilize the crosslinking reaction between the carboxyl group in the polymer and aluminum, which is a component of the skin patch. By doing so, it is possible to have stable shape holding force, adhesiveness and transdermal absorption power of chemicals. In addition, the Republic of Korea Patent Publication No. 10-1322971 is a thermoplastic elastomer 2 ~ 35% by weight, hydrophilic polymer compound 25 ~ in order not to be adversely affected by moisture, have good shape retention and skin compliance, and there is no pool remaining when peeling A pressure sensitive adhesive for skin containing 60% by weight, 16 to 40% by weight of an emollient and 0.01 to 4.8% by weight of a bioactive agent is disclosed.

The pressure-sensitive adhesive composition is optimized for adhesiveness and peelability according to the respective applications, there is no proposal yet for the pressure-sensitive adhesive composition to exhibit the adhesive performance when applied to the skin by adjusting the viscosity of the pressure-sensitive adhesive composition.

In addition, as in the Republic of Korea Patent Publication No. 10-1138081, the hot melt adhesive constituting the first layer of the laminated structure of the hot melt adhesive has a fluidity near the softening point temperature than the hot melt adhesive constituting the second layer, so that Although a technique for increasing the impregnation of the fiber aggregate has been disclosed to change the viscosity according to the temperature range, such a pressure-sensitive adhesive composition is applied to improve the adhesion of absorbent articles such as diapers rather than directly contacting the skin. It is just that.

In addition, the Republic of Korea Patent Publication No. 10-2009-0014253, the matrix layer includes a temperature-sensitive polymer and a water-soluble polymer and the separation phase of the cosmetic ingredient and the polymer adhesive phase, the release of the cosmetic ingredient by the temperature-sensitive polymer when attached to the skin However, the prior art has a problem that it is difficult to produce a product due to the lack of time or degree of the effect of temperature sensitivity because the prior art is to separate the polymer for detachable to the skin and to mix the temperature-sensitive polymer to a certain content .

Republic of Korea Patent Publication No. 10-0903783 Republic of Korea Patent Publication No. 10-1322971 Republic of Korea Patent Registration No. 10-1138081 Republic of Korea Patent Publication No. 10-2009-0014253

The present invention has been made in view of the prior art as described above, the viscosity changes around 30 ℃ of the temperature of the skin improves the adhesion to the skin, the transdermal absorption effect of the cosmetic ingredients and the biomedical polymer with reduced skin irritation It aims at providing the cosmetic composition for body temperature-sensitive adhesive sheets using the temperature sensitive pressure-sensitive adhesive composition containing.

In addition, an object thereof is to provide an adhesive sheet using the cosmetic composition.

The cosmetic composition for a temperature-sensitive adhesive sheet of the present invention for solving the above problems consists of a cosmetic component, 50 to 90% by weight acrylic monomer having a glass transition temperature of 30 to 40 ℃ and 10 to 50% by weight of vinyl acetate monomer It consists of an adhesive component containing resin, an organic solvent, and a hardening | curing agent.

At this time, the acrylic monomer is acrylic acid, ethyl acetate, butyl acrylate, butyl methacrylate, hexyl acrylate, hexyl methacrylate, n-octyl acrylate, n-octyl methacrylate, isooctyl acrylate, isooctyl methacrylate Acrylate, 2-ethylhexyl acrylate, 2-ethylhexyl methacrylate, isononyl acrylate, isononyl methacrylate or any combination thereof.

In addition, the organic solvent is characterized in that it does not contain an aromatic compound.

In addition, the pressure-sensitive adhesive sheet according to the present invention is characterized in that the temperature-sensitive pressure-sensitive adhesive sheet comprising a pressure-sensitive adhesive layer formed of the base material and the cosmetic composition for temperature-sensitive pressure-sensitive adhesive sheet according to claim 1 on one side of the base.

In this case, the substrate is selected from polyethylene, polypropylene, polyethylene terephthalate, polybutene, polybutadiene, polymethylpentene, polyvinyl chloride, vinyl chloride copolymer, polyurethane, polystyrene, polycarbonate, fluorocarbon resin, triacetyl cellulose It may consist of any one of a resin film, a nonwoven fabric, a quality paper, a coated paper, a glassine paper, and a laminated paper.

The cosmetic composition for body temperature-sensitive adhesive sheet of the present invention includes a body temperature-sensitive adhesive composition containing a biomedical polymer that changes in viscosity around 30 ° C of the temperature of the skin, thereby improving adhesion to the skin and transdermal absorption of the cosmetic component. The effect and the effect that a skin irritation is reduced are shown.

In addition, by applying the cosmetic composition to the pressure-sensitive adhesive sheet exhibits the effect of providing a temperature-sensitive pressure-sensitive adhesive sheet.

1 is a spectrum showing the results of differential scanning sequence (DSC) analysis of the pressure-sensitive adhesive composition according to Example 1.
2 is a spectrum showing the results of differential scanning sequence (DSC) analysis of the pressure-sensitive adhesive composition according to Comparative Example 1.

Hereinafter, the present invention will be described in more detail. The terms or words used in this specification and claims are not to be construed as being limited to the common or dictionary meanings, and the inventors may appropriately define the concept of terms in order to best describe their invention. It should be interpreted as meanings and concepts corresponding to the technical idea of the present invention based on the principle that the present invention.

The cosmetic composition for a temperature sensitive adhesive sheet according to the present invention constitutes a pressure sensitive adhesive sheet, and more specifically, a pressure sensitive adhesive layer formed on one surface of a substrate of the pressure sensitive adhesive sheet, which is a composition in which a cosmetic component and a pressure sensitive adhesive component are mixed. It is characterized by.

The cosmetic component is a cosmetic composition comprising a variety of components that have an effect on skin care, usually made of any one or more of diluents, softeners, humectants, emulsifiers, surfactants, bioactive substances and purified water contained in the cosmetic composition. Can be.

The diluent is a component that dilutes and uniformly dissolves the cosmetic composition at an appropriate concentration. Water and C1-C4 monohydric alcohol and propylene glycol, polyethylene glycol, polypropylene glycol, propylene glycol, polyethylene glycol, polypropylene glycol, glycerol, butylene glycol Hydrophilic and low molecular weight such as 1,2,4-butanetriol, sorbitol ester, 1,2,6-hexanetriol, ethanol, iso-propanol, sorbitol ester, ethoxylated ether, propoxylated ether Glycols, polyols, and the like. The content of the diluent is preferably 5 to 30 parts by weight.

The softener is a component that acts to smooth the skin, increase the softness and softness of the skin, prevent or remove dry skin, or protect the skin, and is a vegetable oil or hydrogenated vegetable oil, animal fat or oil, alkyl ether Preference is given to using one or more mixtures selected from the group consisting of, carboxylic acid ethers, isocetyl alcohol, castor oil or tocopherol acetate and mixtures thereof. In addition, the softener is preferably used in the range of 3 to 15 parts by weight.

The moisturizing agent is a component that improves the skin's moisturizing properties, such as propylene glycol, dipropylene glycol, butylene glycol, polypropylene glycol, polyethylene glycol, sorbitol, hydroxypropyl sorbitol, erythritol, pentitol ( threitol, pentaerythritol, xylitol, glucitol, mannitol, hexylene glycol, glycerin, sodium hyaluronate, sodium hyaluronate or dimethicone Can be. In addition, the moisturizing agent is preferably used in the range of 10 to 20 parts by weight in view of the moisturizing effect.

The surfactant is a component which serves to disperse and suspend the discontinuous phase in the continuous phase, and the surfactant used in general if the selected agent is chemically and physically compatible with the components of the composition and provides the required properties. Can be used. Preferred surfactants include ester-based oils, isohexatecane, cetanol, stearyl alcohol, oleyl alcohol, lauric acid, myristic acid, palmitic acid or dimethyloctanoic acid, etc., in the range of 1 to about 10 parts by weight. Preference is given to using at.

In addition, the emulsifiers include PEG-10 hydrogenate castor oil, PEG-100 hydrogenate castor oil, mineral oil, sorbitan cisquinolate, propylene glycol dicaprylate, stearic acid, triethanolamine, castor oil, etc. It is preferable to use in the range of 1-10 weight part.

In addition, as a physiologically active substance for skin care, water-soluble vitamins including vitamin B group and vitamin C group, fat soluble vitamins such as vitamin A group such as retinol and palmitate retinol, vitamin D group, vitamin E group and vitamin F group Vitamins and natural but commonly used extracts such as arbutin and ginseng extract. The content of the bioactive substance is suitably in the range of 2 to 10 parts by weight.

In addition, the component that may be additionally added in the preparation of the cosmetic composition may be any one or more of a viscosity modifier, a neutralizer, a chelating agent, astringents, preservatives, decontaminants.

The viscosity modifier is to function to adjust the viscosity of the cosmetic component after emulsification, and commonly used polyglyceryl methacrylate, carboxyl vinyl poly, hydroxyethyl cellulose or carbomer may be used. The content of the viscosity modifier may be adjusted to appropriately reduce the viscosity according to the formulation of the cosmetic ingredient.

The neutralizing agent is added after the addition of the thickening agent to adjust the pH of the product, and may include diethanolamine, triethanolamine, arginine and the like.

The chelating agent acts as a protection against environmental factors that can lead to UV radiation and skin damage causing excessive scale rings or tissue changes in the stratum corneum. Tetraacetic acid, furyldioxime or sodium tetraacetic acid may be used as the chelating agent, and a suitable amount is 0.01 to 1.0 parts by weight.

The astringent acts to temporarily shrink pores, and zinc oxide, zinc sulfate, allantoan, hydroxyaluminum, citric acid, lactic acid, aluminum sulfate, aluminum chloride, zinc stearate, or backwood extract may be used.

The preservative is methyl paraben, ethyl paraben, propyl paraben, butyl paraben, isobutyl paraben, phenoxyethanol and the like are used, it is preferable to use in the range of 0.01 to 1.0 parts by weight.

The decontaminant serves to cleanly remove contaminants remaining on the skin, and sodium tetraacetic acid is used.

The cosmetic component prepared as described above is combined with the pressure-sensitive adhesive component to form a cosmetic composition for a temperature-sensitive adhesive sheet of the present invention, wherein the cosmetic composition includes a biomedical polymer that varies in viscosity around 30 ° C., which is the temperature of the skin. In particular, it is preferable to include a resin composed of 50 to 90% by weight of an acrylic monomer having a glass transition temperature of 30 to 40 ° C and 10 to 50% by weight of a vinyl acetate monomer. Biomedical polymers prepared using such monomers are effective to soften the pressure-sensitive adhesive component when attached to the skin can be improved adhesion performance.

That is, when the acrylic monomer and the vinyl acetate monomer constitute a polymer in a polymerized form, the components and physical properties of the pressure-sensitive adhesive which can be used as the cosmetic composition desired in the present invention can be achieved.

In addition, the cosmetic composition may be obtained by separately preparing the cosmetic component and the pressure-sensitive adhesive component and then blending them.

In general, the pressure-sensitive adhesive composition used in the skin adhesive sheet is a resin obtained by polymerizing an acrylic monomer and a rubber monomer. Toluene is used as an organic solvent and a tackifier is added together with a resin, an organic solvent, and a curing agent. The required adhesion performance is obtained. In this case, the resin composition, the organic solvent, the curing agent, the tackifier, etc. are blended at one time to prepare the pressure-sensitive adhesive composition in a single process, but the polymerization conversion rate is generally 95% or more.

On the other hand, in this invention, in order to satisfy the characteristic calculated | required by the adhesive composition adhering to skin, an adhesive composition is manufactured, without using an aromatic solvent like toluene. To this end, in addition to not using an aromatic solvent, by not using a tackifier containing a large amount of acid, the amount of acid contained in the resin is greatly reduced to solve skin irritation.

In the present invention, when the pressure-sensitive adhesive component is produced, the components such as resin, organic solvent, curing agent, etc. are not manufactured in a single step, but each step of mixing monomers, mixing a polymerization initiator, mixing an organic solvent, mixing a curing agent, and the like. By increasing the conversion rate to 98% or more. For example, when preparing a resin, acrylic acid, which is a functional group, and other acrylic monomers and vinyl acetate monomers may be sequentially added to a reactor, mixed, and then a polymerization initiator is added to obtain high polymerization conversion and crosslinking density without using a tackifier. Can be. In addition, by employing such a process, the content of unreacted monomers is greatly reduced, thereby greatly reducing the harmfulness to the skin, skin irritation, and odor due to the unreacted monomers.

As the acrylic monomer, any one having a glass transition temperature of 30 to 40 ° C. may be used. For example, acrylic acid, ethyl acetate, butyl acrylate, butyl methacrylate, hexyl acrylate, hexyl methacrylate, n- Octyl acrylate, n-octyl methacrylate, isooctyl acrylate, isooctyl methacrylate, 2-ethylhexyl acrylate, 2-ethylhexyl methacrylate, isononyl acrylate, isononyl methacrylate have. Such an acrylic monomer may be used as one component, but a better effect may be obtained by using two or more components in combination. For example, acrylic acid is about 200 times higher in reactivity than a general monomer, and thus, acrylic acid and other monomers may be mixed with each other to increase the degree of polymerization and reduce unreacted monomers. Can be. Therefore, it is preferable that it is a mixture of 2 or more acrylic monomers containing acrylic acid as an acryl-type monomer.

The acrylic monomer may be used in the range of 50 to 90% by weight. If the content of the acrylic monomer outside the above range is too small, the effect of increasing the viscosity in the vicinity of the target 30 ℃ in the present invention can not be obtained, if it is too large it is preferable to use in the above range because there is a problem in peeling performance.

In addition, the vinyl acetate monomer blended with the acrylic monomer is mixed in the range of 10 to 50% by weight, the vinyl acetate monomer has a glass transition temperature of 29 to 30 ℃ and the polymerization of the acrylic monomer to form a copolymer of the present invention To achieve the desired physical properties of the pressure-sensitive adhesive. If the content of the vinyl acetate monomer is too small or too large, it is impossible to obtain the adhesive force and peeling force required in the present invention, and when applied to the adhesive sheet, the adhesive force may be insufficient or may damage the skin when peeling and the active ingredient is transdermal. The problem that the absorption effect is lowered arises.

By adding a polymerization initiator with respect to the acrylic monomer and the vinyl acetate monomer, a polymerization reaction occurs, thereby obtaining a resin for pressure-sensitive adhesive. As the polymerization initiator, any one can be used as long as it can cause the polymerization reaction of the acrylic monomer and the vinyl acetate monomer, and it is preferable to use azobis isobutyronitrile (AIBN), benzoyl peroxide (BPO), or the like. Do.

As described above, an organic solvent and a curing agent may be added to the resin obtained by polymerization of the monomer to obtain a body temperature-sensitive adhesive component of the present invention.

The organic solvent may be made of any one or a combination of ethyl acetate, cyclohexane, n-hexane, acetone, dimethyl carbonate, methanol, ethanol, isopropyl alcohol. The organic solvent may be used in an amount of 10 to 200 parts by weight based on 100 parts by weight of the blend containing the acrylic monomer and the vinyl acetate monomer. If the content of the organic solvent is too small, a problem may occur in the process of forming the pressure-sensitive adhesive layer because the concentration of the pressure-sensitive adhesive resin is high, and if too much, the content of the solid content is reduced because the content of the solid content is reduced.

As the curing agent, any one can be used as long as it can polymerize an acrylic monomer and a vinyl acetate monomer, and for example, any of isocyanate compounds, epoxy resins, melamine resins, urea resins, dialdehydes, and metal chelate compounds. It may consist of one or a combination of these.

The curing agent may be used in an amount of 0.1 to 10 parts by weight based on 100 parts by weight of the blend containing the acrylic monomer and the vinyl acetate monomer. When the content of the hardener is too small, the durability may be lowered because cohesive failure occurs under high temperature and high humidity conditions, and when too much, fluidity may decrease because of compatibility decrease.

When the pressure-sensitive adhesive composition according to the present invention is analyzed by GPC, in the general pressure-sensitive adhesive composition, a main peak appears at a molecular weight of 250,000 to 350,000 and a peak due to a tackifier is observed at about 1,000, but the pressure-sensitive adhesive composition according to the present invention has a molecular weight of 250,000 to 350,000 In addition to the main peak at, additional peaks are observed at 20,000 to 50,000. This means that the resin of the present invention is composed of two kinds of polymers having different molecular weights, and it has been found that the two kinds of polymers cause a viscosity change due to a temperature change near the body temperature.

After preparing a cosmetic composition by mixing the pressure-sensitive adhesive component and the cosmetic component having the above configuration, by forming the pressure-sensitive adhesive layer on one surface of the substrate constituting the pressure-sensitive adhesive sheet, the pressure-sensitive adhesive sheet of the present invention can be obtained. .

The substrate constituting the pressure sensitive adhesive sheet has a releasability, and is polyethylene, polypropylene, polyethylene terephthalate, polybutene, polybutadiene, polymethylpentene, polyvinyl chloride, vinyl chloride copolymer, polyurethane, polystyrene, polycarbonate, fluorine A resin film selected from resin and triacetyl cellulose can be used, and any one of nonwoven fabric, fine paper, coated paper, glassine paper, and laminated paper can also be used.

The pressure-sensitive adhesive layer may be formed by adding an organic solvent and a curing agent to the pressure-sensitive adhesive resin to adjust the viscosity to a suitable level for the coating operation, and then applying and curing the pressure-sensitive adhesive layer on the substrate. In addition, since the cosmetic component is collected in the matrix of the resin constituting the adhesive by curing, the cosmetic component can be eluted and absorbed into the skin only when the viscosity changes in response to body temperature.

The pressure-sensitive adhesive layer may be formed by a method used to manufacture a conventional adhesive sheet such as a bar coating method, a reverse roll coating method, a knife coating method, a roll knife coating method, a gravure coating method, a doctor blade coating method, a slot die coating method, and the like. After applying the pressure-sensitive adhesive, it may be dried and cured to form a pressure-sensitive adhesive layer to finally have a thickness of 10 to 100㎛.

Hereinafter, the present invention will be described in more detail with reference to Examples.

Example 1

To prepare the cosmetic components, 20 parts by weight of ethanol, 8 parts by weight of castor oil, 10 parts by weight of dimethicone, 5 parts by weight of ethylene glycol, 0.5 parts by weight of polyglyceryl methacrylate, 0.2 parts by weight of triethanolamine, and 0.5 parts of zinc stearate Parts, 0.5 part by weight of sodium tetraacetic acid and 20 parts by weight of arbutin were mixed.

19 parts by weight of ethyl acrylate monomer (EAM), 60 parts by weight of 2-ethylhexyl acrylate monomer (2-EHA), 20 parts by weight of vinyl acrylate monomer (VAM), 1 part by weight of acrylic acid to prepare the pressure-sensitive adhesive component, and As a polymerization initiator, 0.5 part by weight of AIBN (Azobis isobutyronitrile) was charged into a four-neck 1 liter glass reactor and polymerized to prepare a pressure-sensitive adhesive resin. Dilute with ethyl acetate, an organic solvent, and add 5 parts by weight of an isocyanate curing agent so that the solid content of the pressure-sensitive adhesive resin is 40%.

The coating liquid of the cosmetic composition was prepared by mixing the prepared cosmetic components and pressure-sensitive adhesive components. Thereafter, the coating solution was coated and dried to a thickness of 25 μm on a release surface of a polyethylene terephthalate (PET) film having a thickness of 25 μm to prepare an adhesive layer. The pressure-sensitive adhesive layer produced by this process was laminated with a corona treated polyethylene terephthalate (PET) film to prepare a single-sided pressure-sensitive adhesive sheet.

Comparative Example 1

Cosmetic ingredients were prepared in the same manner as in Example 1.

For preparing the pressure-sensitive adhesive component, 30 parts by weight of ethyl acrylate monomer (EAM), 30 parts by weight of butyl acrylate monomer (BAM), 35 parts by weight of 2-ethylhexyl acrylate monomer (2-EHA), 1 part by weight of acrylic acid, And 0.5 parts by weight of AIBN (Azobis isobutyronitrile) as a polymerization initiator was added to a four-neck 1 liter glass reactor and polymerized to prepare an adhesive resin. Then, the adhesive composition was diluted with ethyl acetate, an organic solvent, so that the solid content of the adhesive composition was 40%, and 5 parts by weight of an isocyanate curing agent was prepared.

The coating liquid of the cosmetic composition was prepared by mixing the prepared cosmetic components and pressure-sensitive adhesive components. Thereafter, the coating solution was coated and dried to a thickness of 25 μm on a release surface of a polyethylene terephthalate (PET) film having a thickness of 25 μm to prepare an adhesive layer. The pressure-sensitive adhesive layer made of this process was laminated with a corona treated polyethylene terephthalate (PET) film to prepare a single-sided pressure-sensitive adhesive sheet.

Comparative Example 2

Cosmetic ingredients were prepared in the same manner as in Example 1.

For the preparation of the pressure-sensitive adhesive component, 39 parts by weight of ethyl acrylate monomer (EAM), 60 parts by weight of 2-ethylhexyl acrylate monomer (2-EHA), 1 part by weight of acrylic acid, 0.5 weight of Azobis isobutyronitrile (AIBN) as a polymerization initiator The part was put into a 4-neck 1 liter glass reactor and polymerized to prepare an adhesive composition. Then, the adhesive composition was diluted with ethyl acetate, an organic solvent, so that the solid content of the adhesive composition was 40%, and 5 parts by weight of an isocyanate curing agent was prepared.

The coating liquid of the cosmetic composition was prepared by mixing the prepared cosmetic components and pressure-sensitive adhesive components.

Thereafter, the coating solution was coated and dried to a thickness of 25 μm on a release surface of a polyethylene terephthalate (PET) film having a thickness of 25 μm to prepare an adhesive layer. The pressure-sensitive adhesive layer made of this process was laminated with a corona treated polyethylene terephthalate (PET) film to prepare a single-sided pressure-sensitive adhesive sheet.

The prepared adhesive sheet was evaluated for adhesive strength, holding strength, heat resistance and skin irritation according to temperature change.

In order to measure the adhesive force, a pressure-sensitive adhesive sample cut into a size of 25 × 200 mm was mounted on a peel tester, and a 180 ° peel off test was performed at a peel rate of 300 mm / min. In order to measure the change in temperature, the pressure-sensitive adhesive sheet was warmed to room temperature, 30, 35, 40 ° C., and then tested for adhesion.

Holding force was measured according to KST-1028. Prepare two pieces of adhesive sheet with width × length of 25 × 150mm, attach them to SUS 304 steel plate with 25 × 25mm, and prepare specimens by reciprocating and pressing twice at 25mm / sec using 2kg roller. It was. After standing at 23 ± 2 ℃, relative humidity 50 ± 2% for 30 minutes. The specimen was placed in a chamber at 80 ° C. for 1 hour while applying a weight of 1 kg using a weight, and after 1 hour, the distance from the pushed distance or the test plate was measured.

Specimens for the measurement of heat resistance were prepared under the same conditions as the holding force test, the specimen was left in the chamber under a load of 500g using a weight, and heated up by 10 ℃ per 10 minutes in the range of 50 ~ 150 ℃, 150 After reaching the temperature was allowed to stand for 30 minutes. At this time, the temperature dropped while heating up to 150 ℃ was measured, if the temperature does not fall even 150 ℃ left 30 minutes to measure the distance pushed.

Skin irritation was measured in accordance with the Toxicity Test Standards for Drugs, etc. (2015-82, 2015.11.11.) As announced by the Ministry of Food and Drug Safety. Six young, healthy white rabbits (weight 2.0 to 3.0 kg) are used as test animals. 0.5 g of the pressure-sensitive adhesive composition was applied to the skin on the back of the shaved skin at 2.5 x 2.5 cm of rubbed and skin and two places of rub and skin, covered with gauze and fixed with tape. In addition, erythema and crust formation were observed 24 and 72 hours after application. If there was no erythema at all, “×”, and if there was a very mild erythema (only visible to the naked eye), “△”, a clear erythema was observed. “○”, slightly severe erythema is observed, “◎”, severe erythema (redness of blush) and mild crust is observed as “⊙”.

In addition, the initial content was measured in the pressure-sensitive adhesive layer of arbutin used as a bioactive material, and after 24 hours of application, the pressure-sensitive adhesive layer was recovered, and the arbutin content in the pressure-sensitive adhesive layer was measured to calculate a reduction rate of arbutin. The content of arbutin was all measured using a gas chromatograph mass spectrometer (GC / MS). The results are shown in Table 1.

Example 1 Comparative Example 1 Comparative Example 2 Room Temperature Adhesion (gf / in) 1,200 1,000 900 30 ℃ adhesive force (gf / in) 2,000 850 850 35 ℃ Adhesive force (gf / in) 1,900 800 780 40 ℃ Adhesive force (gf / in) 1,700 750 700 Holding force (mm) <1 <1 <1 Heat resistance degree (℃) 150 150 150 Skin irritation × ○ △ Arbutin Reduction > 99% 96.6% 97.5%

Looking at the results of Table 1, the pressure-sensitive adhesive layer of Example 1 was found to increase the adhesive force at room temperature 1,200 gf / in, but the adhesive force at 30 ℃ to 2,000 gf / in 167% to increase the adhesive strength when the adhesive sheet is attached to the skin This increased adhesion and detachment from the skin resulted in a decrease in body temperature.

In addition, the results of differential scanning sequence (DSC) analysis of the pressure-sensitive adhesive composition of Example 1 is the same as that of Figure 1, the peak of the phase change at 34.2 ℃ shows a result consistent with the experimental results of the viscosity change in the temperature range similar to the body temperature Got it.

On the other hand, in Comparative Examples 1 and 2, the adhesive force was rather decreased at 30 to 40 ° C. as compared to the adhesive force at room temperature, so that the characteristic of responding to body temperature did not appear at all. Differential scanning sequence (DSC) analysis results of the pressure-sensitive adhesive composition of Comparative Example 1 is the same as that of Figure 2 in the temperature range of 30 to 40 ℃ no peak is observed according to the phase change there is no change in viscosity in the temperature range similar to the body temperature Could know.

Although the same results were obtained in Example 1 and Comparative Examples 1 and 2 in the holding force and the heat resistance, the body temperature sensitivity was found only in Example 1 to which a resin polymerized with an acrylic monomer and a vinyl acetate monomer was applied. By including the resin which concerns on this invention, the result which shows the characteristic applicable to a temperature sensitive adhesive sheet is suggested.

In addition, as a result of performing the skin stimulation test, in Example 1, no erythema was observed, so that no skin irritation was observed, but in Comparative Examples 1 and 2, erythema was observed, indicating that there was a skin irritation. Therefore, it was confirmed to show a difference in the degree of skin irritation depending on the type of resin applied to the pressure-sensitive adhesive composition.

In addition, as a result of measuring the amount of moisture is transferred to the surface of the pressure-sensitive adhesive layer of the adhesive sheets of Examples 1 and Comparative Examples 1 and 2, in Example 1, after about 90 minutes, the amount of water released was about 25%. In the case of Examples 1 and 2, 16% and 19% showed a slow rate of water formation on the pressure-sensitive adhesive layer surface. From these results, the delivery rate of the cosmetic component was found to be lower than that of Example 1.

In addition, looking at the result of measuring the reduction rate of arbutin, in Example 1, arbutin was reduced by more than 99% after 24 hours, it was estimated that almost all arbutin is supplied to the skin. On the other hand, in Comparative Examples 1 and 2, the reduction rate of albitine was 96.6% and 97.5%, respectively, indicating that the reduction rate of arbutin was lower than that of Example 1. This is because in the case of Example 1 the viscosity is changed around the body temperature, the movement of the bioactive material mixed in the pressure-sensitive adhesive layer is active, but in Comparative Examples 1 and 2 there is no body temperature sensitive effect, so the movement of the bioactive material in the general adhesive sheet This is because it shows a similar behavior to. This is a result suggesting that by applying the cosmetic composition of the present invention to the pressure-sensitive adhesive sheet can be more efficiently absorbed into the skin.

Although the present invention has been described with reference to preferred embodiments as described above, the present invention is not limited to the above-described embodiments, and various modifications may be made by those skilled in the art without departing from the spirit of the present invention. You can change it. Such modifications and variations are intended to be within the scope of the invention and the appended claims.

Claims (5)

Cosmetic ingredients;
A pressure sensitive adhesive component comprising a resin, an organic solvent, and a curing agent comprising 50 to 90% by weight of an acrylic monomer having a glass transition temperature of 30 to 40 ° C and 10 to 50% by weight of a vinyl acetate monomer;
Cosmetic composition for body-sensitive adhesive sheet, characterized in that consisting of.
The method according to claim 1,
The acrylic monomers are acrylic acid, ethyl acetate, butyl acrylate, butyl methacrylate, hexyl acrylate, hexyl methacrylate, n-octyl acrylate, n-octyl methacrylate, isooctyl acrylate and isooctyl methacrylate. , 2-ethylhexyl acrylate, 2-ethylhexyl methacrylate, isononyl acrylate, isononyl methacrylate any one or a combination thereof Cosmetic composition for temperature-sensitive adhesive sheet.
The method according to claim 1,
The organic solvent is a cosmetic composition for a temperature-sensitive adhesive sheet, characterized in that it does not contain an aromatic compound.
Body-sensitive pressure-sensitive adhesive sheet comprising a pressure-sensitive adhesive layer formed of the base material and the cosmetic composition for a temperature-sensitive pressure-sensitive adhesive sheet according to claim 1 on one side of the base.
The method according to claim 4,
The substrate is a resin film selected from polyethylene, polypropylene, polyethylene terephthalate, polybutene, polybutadiene, polymethylpentene, polyvinyl chloride, vinyl chloride copolymer, polyurethane, polystyrene, polycarbonate, fluorocarbon resin, triacetyl cellulose , Nonwoven fabric, good-quality paper, coated paper, glassine paper, laminated paper, any one of the body temperature-sensitive adhesive sheet characterized in that.

Images